Details of the Target

General Information of Target

Target ID LDTP11502
Target Name Transcription regulator protein BACH2 (BACH2)
Gene Name BACH2
Gene ID 60468
Synonyms
Transcription regulator protein BACH2; BTB and CNC homolog 2
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSLRRHIGNPEYLMKRIPQNPRYQHIKSRLDTGNSMTKYTEKLEEIKKNYRYKKDELFKR
LKVTTFAQLIIQVASLSDQTLEVTAEEIQRLEDNDSAASDPDAETTARTNGKGNPGEQSP
SPEQFINNAGAGDSSRSTLQSVISGVGELDLDKGPVKKAEPHTKDKPYPDCPFLLLDVRD
RDSYQQCHIVGAYSYPIATLSRTMNPYSNDILEYKNAHGKIIILYDDDERLASQAATTMC
ERGFENLFMLSGGLKVLAQKFPEGLITGSLPASCQQALPPGSARKRSSPKGPPLPAENKW
RFTPEDLKKIEYYLEEEQGPADHPSRLNQANSSGRESKVPGARSAQNLPGGGPASHSNPR
SLSSGHLQGKPWK
Target Bioclass
Transcription factor
Family
BZIP family, CNC subfamily
Subcellular location
Cytoplasm
Function
Transcriptional regulator that acts as a repressor or activator. Binds to Maf recognition elements (MARE). Plays an important role in coordinating transcription activation and repression by MAFK. Induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1. Positively regulates the nuclear import of actin. Is a key regulator of adaptive immunity, crucial for the maintenance of regulatory T-cell function and B-cell maturation.
Uniprot ID
Q9BYV9
Ensemble ID
ENST00000257749.9
HGNC ID
HGNC:14078
ChEMBL ID
CHEMBL5069364

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C370(3.71)  LDD3339  [1]
IA-alkyne
 Probe Info  		C670, C676(8.11); C370(20.00); C340(10.10); C238(5.07)  LDD1704  [2]
NAIA_4
 Probe Info  		N.A.  LDD2226  [3]
IPM
 Probe Info  		C370(0.00); C328(0.00)  LDD2156  [4]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0215  AC10 HEK-293T C370(0.92)  LDD1508  [5]
 LDCM0226  AC11 HEK-293T C370(0.95)  LDD1509  [5]
 LDCM0237  AC12 HEK-293T C370(0.99)  LDD1510  [5]
 LDCM0259  AC14 HEK-293T C370(1.02)  LDD1512  [5]
 LDCM0270  AC15 HEK-293T C370(0.97)  LDD1513  [5]
 LDCM0277  AC18 HEK-293T C370(0.99)  LDD1516  [5]
 LDCM0278  AC19 HEK-293T C370(0.92)  LDD1517  [5]
 LDCM0279  AC2 HEK-293T C370(1.02)  LDD1518  [5]
 LDCM0280  AC20 HEK-293T C370(0.98)  LDD1519  [5]
 LDCM0281  AC21 HEK-293T C370(0.88); C420(0.96)  LDD1520  [5]
 LDCM0282  AC22 HEK-293T C370(1.00)  LDD1521  [5]
 LDCM0283  AC23 HEK-293T C370(1.02)  LDD1522  [5]
 LDCM0284  AC24 HEK-293T C370(1.06)  LDD1523  [5]
 LDCM0286  AC26 HEK-293T C370(1.02)  LDD1525  [5]
 LDCM0287  AC27 HEK-293T C370(1.01)  LDD1526  [5]
 LDCM0288  AC28 HEK-293T C370(0.99)  LDD1527  [5]
 LDCM0289  AC29 HEK-293T C370(0.96); C420(0.93)  LDD1528  [5]
 LDCM0290  AC3 HEK-293T C370(1.04)  LDD1529  [5]
 LDCM0291  AC30 HEK-293T C370(1.15)  LDD1530  [5]
 LDCM0292  AC31 HEK-293T C370(1.00)  LDD1531  [5]
 LDCM0293  AC32 HEK-293T C370(1.00)  LDD1532  [5]
 LDCM0295  AC34 HEK-293T C370(1.01)  LDD1534  [5]
 LDCM0296  AC35 HEK-293T C370(0.97)  LDD1535  [5]
 LDCM0297  AC36 HEK-293T C370(1.10)  LDD1536  [5]
 LDCM0298  AC37 HEK-293T C370(1.02); C420(0.90)  LDD1537  [5]
 LDCM0299  AC38 HEK-293T C370(0.98)  LDD1538  [5]
 LDCM0300  AC39 HEK-293T C370(0.99)  LDD1539  [5]
 LDCM0301  AC4 HEK-293T C370(1.02)  LDD1540  [5]
 LDCM0302  AC40 HEK-293T C370(0.91)  LDD1541  [5]
 LDCM0304  AC42 HEK-293T C370(1.03)  LDD1543  [5]
 LDCM0305  AC43 HEK-293T C370(0.96)  LDD1544  [5]
 LDCM0306  AC44 HEK-293T C370(0.94)  LDD1545  [5]
 LDCM0307  AC45 HEK-293T C370(1.05); C420(1.00)  LDD1546  [5]
 LDCM0308  AC46 HEK-293T C370(0.97)  LDD1547  [5]
 LDCM0309  AC47 HEK-293T C370(1.05)  LDD1548  [5]
 LDCM0310  AC48 HEK-293T C370(0.93)  LDD1549  [5]
 LDCM0312  AC5 HEK-293T C370(0.98); C420(1.10)  LDD1551  [5]
 LDCM0313  AC50 HEK-293T C370(1.03)  LDD1552  [5]
 LDCM0314  AC51 HEK-293T C370(1.10)  LDD1553  [5]
 LDCM0315  AC52 HEK-293T C370(1.05)  LDD1554  [5]
 LDCM0316  AC53 HEK-293T C370(1.08); C420(1.03)  LDD1555  [5]
 LDCM0317  AC54 HEK-293T C370(1.08)  LDD1556  [5]
 LDCM0318  AC55 HEK-293T C370(0.98)  LDD1557  [5]
 LDCM0319  AC56 HEK-293T C370(0.95)  LDD1558  [5]
 LDCM0321  AC58 HEK-293T C370(0.93)  LDD1560  [5]
 LDCM0322  AC59 HEK-293T C370(1.08)  LDD1561  [5]
 LDCM0323  AC6 HEK-293T C370(1.16)  LDD1562  [5]
 LDCM0324  AC60 HEK-293T C370(1.09)  LDD1563  [5]
 LDCM0325  AC61 HEK-293T C370(1.03); C420(0.92)  LDD1564  [5]
 LDCM0326  AC62 HEK-293T C370(1.10)  LDD1565  [5]
 LDCM0327  AC63 HEK-293T C370(1.00)  LDD1566  [5]
 LDCM0328  AC64 HEK-293T C370(0.97)  LDD1567  [5]
 LDCM0334  AC7 HEK-293T C370(0.99)  LDD1568  [5]
 LDCM0345  AC8 HEK-293T C370(0.88)  LDD1569  [5]
 LDCM0248  AKOS034007472 HEK-293T C370(1.01); C420(0.88)  LDD1511  [5]
 LDCM0275  AKOS034007705 HEK-293T C370(0.84)  LDD1514  [5]
 LDCM0367  CL1 HEK-293T C370(0.97)  LDD1571  [5]
 LDCM0368  CL10 HEK-293T C370(1.31)  LDD1572  [5]
 LDCM0369  CL100 HEK-293T C370(1.07); C238(0.99)  LDD1573  [5]
 LDCM0370  CL101 HEK-293T C370(0.94)  LDD1574  [5]
 LDCM0371  CL102 HEK-293T C370(1.11); C238(1.07)  LDD1575  [5]
 LDCM0372  CL103 HEK-293T C238(1.03)  LDD1576  [5]
 LDCM0373  CL104 HEK-293T C370(1.22); C238(0.97)  LDD1577  [5]
 LDCM0374  CL105 HEK-293T C370(1.00)  LDD1578  [5]
 LDCM0375  CL106 HEK-293T C370(0.94); C238(1.02)  LDD1579  [5]
 LDCM0376  CL107 HEK-293T C238(0.82)  LDD1580  [5]
 LDCM0377  CL108 HEK-293T C370(1.12); C238(0.97)  LDD1581  [5]
 LDCM0378  CL109 HEK-293T C370(0.92)  LDD1582  [5]
 LDCM0379  CL11 HEK-293T C370(1.17)  LDD1583  [5]
 LDCM0380  CL110 HEK-293T C370(1.00); C238(0.86)  LDD1584  [5]
 LDCM0381  CL111 HEK-293T C238(0.94)  LDD1585  [5]
 LDCM0382  CL112 HEK-293T C370(1.14); C238(1.05)  LDD1586  [5]
 LDCM0383  CL113 HEK-293T C370(1.06)  LDD1587  [5]
 LDCM0384  CL114 HEK-293T C370(1.09); C238(0.91)  LDD1588  [5]
 LDCM0385  CL115 HEK-293T C238(0.94)  LDD1589  [5]
 LDCM0386  CL116 HEK-293T C370(1.08); C238(0.96)  LDD1590  [5]
 LDCM0387  CL117 HEK-293T C370(1.08)  LDD1591  [5]
 LDCM0388  CL118 HEK-293T C370(1.15); C238(1.16)  LDD1592  [5]
 LDCM0389  CL119 HEK-293T C238(0.98)  LDD1593  [5]
 LDCM0390  CL12 HEK-293T C370(0.96)  LDD1594  [5]
 LDCM0391  CL120 HEK-293T C370(0.99); C238(0.96)  LDD1595  [5]
 LDCM0392  CL121 HEK-293T C370(1.09)  LDD1596  [5]
 LDCM0393  CL122 HEK-293T C370(1.06); C238(1.00)  LDD1597  [5]
 LDCM0394  CL123 HEK-293T C238(0.92)  LDD1598  [5]
 LDCM0395  CL124 HEK-293T C370(1.08); C238(0.85)  LDD1599  [5]
 LDCM0396  CL125 HEK-293T C370(0.95)  LDD1600  [5]
 LDCM0397  CL126 HEK-293T C370(1.17); C238(1.09)  LDD1601  [5]
 LDCM0398  CL127 HEK-293T C238(0.76)  LDD1602  [5]
 LDCM0399  CL128 HEK-293T C370(1.09); C238(0.92)  LDD1603  [5]
 LDCM0400  CL13 HEK-293T C370(1.01)  LDD1604  [5]
 LDCM0401  CL14 HEK-293T C370(1.08); C238(1.00)  LDD1605  [5]
 LDCM0402  CL15 HEK-293T C238(1.20)  LDD1606  [5]
 LDCM0403  CL16 HEK-293T C370(1.19); C238(0.77)  LDD1607  [5]
 LDCM0405  CL18 HEK-293T C370(1.06)  LDD1609  [5]
 LDCM0406  CL19 HEK-293T C370(0.97)  LDD1610  [5]
 LDCM0407  CL2 HEK-293T C370(1.12); C238(1.02)  LDD1611  [5]
 LDCM0408  CL20 HEK-293T C370(0.99)  LDD1612  [5]
 LDCM0409  CL21 HEK-293T C370(1.29); C420(1.08)  LDD1613  [5]
 LDCM0410  CL22 HEK-293T C370(1.04)  LDD1614  [5]
 LDCM0411  CL23 HEK-293T C370(1.00)  LDD1615  [5]
 LDCM0412  CL24 HEK-293T C370(1.07)  LDD1616  [5]
 LDCM0413  CL25 HEK-293T C370(0.98)  LDD1617  [5]
 LDCM0414  CL26 HEK-293T C370(1.04); C238(1.04)  LDD1618  [5]
 LDCM0415  CL27 HEK-293T C238(0.85)  LDD1619  [5]
 LDCM0416  CL28 HEK-293T C370(1.17); C238(0.89)  LDD1620  [5]
 LDCM0418  CL3 HEK-293T C238(1.00)  LDD1622  [5]
 LDCM0419  CL30 HEK-293T C370(1.04)  LDD1623  [5]
 LDCM0420  CL31 HEK-293T C370(1.11)  LDD1624  [5]
 LDCM0421  CL32 HEK-293T C370(1.06)  LDD1625  [5]
 LDCM0422  CL33 HEK-293T C370(1.19); C420(1.03)  LDD1626  [5]
 LDCM0423  CL34 HEK-293T C370(1.12)  LDD1627  [5]
 LDCM0424  CL35 HEK-293T C370(0.96)  LDD1628  [5]
 LDCM0425  CL36 HEK-293T C370(0.90)  LDD1629  [5]
 LDCM0426  CL37 HEK-293T C370(0.91)  LDD1630  [5]
 LDCM0428  CL39 HEK-293T C238(0.86)  LDD1632  [5]
 LDCM0429  CL4 HEK-293T C370(1.05); C238(0.93)  LDD1633  [5]
 LDCM0430  CL40 HEK-293T C370(0.97); C238(0.96)  LDD1634  [5]
 LDCM0432  CL42 HEK-293T C370(1.01)  LDD1636  [5]
 LDCM0433  CL43 HEK-293T C370(0.97)  LDD1637  [5]
 LDCM0434  CL44 HEK-293T C370(1.18)  LDD1638  [5]
 LDCM0435  CL45 HEK-293T C370(1.06); C420(0.93)  LDD1639  [5]
 LDCM0436  CL46 HEK-293T C370(1.28)  LDD1640  [5]
 LDCM0437  CL47 HEK-293T C370(1.16)  LDD1641  [5]
 LDCM0438  CL48 HEK-293T C370(0.96)  LDD1642  [5]
 LDCM0439  CL49 HEK-293T C370(1.01)  LDD1643  [5]
 LDCM0441  CL50 HEK-293T C370(1.15); C238(1.04)  LDD1645  [5]
 LDCM0443  CL52 HEK-293T C370(1.18); C238(0.89)  LDD1646  [5]
 LDCM0445  CL54 HEK-293T C370(1.03)  LDD1648  [5]
 LDCM0446  CL55 HEK-293T C370(1.10)  LDD1649  [5]
 LDCM0447  CL56 HEK-293T C370(1.11)  LDD1650  [5]
 LDCM0448  CL57 HEK-293T C370(1.42); C420(1.06)  LDD1651  [5]
 LDCM0449  CL58 HEK-293T C370(1.15)  LDD1652  [5]
 LDCM0450  CL59 HEK-293T C370(1.19)  LDD1653  [5]
 LDCM0451  CL6 HEK-293T C370(1.02)  LDD1654  [5]
 LDCM0452  CL60 HEK-293T C370(0.97)  LDD1655  [5]
 LDCM0453  CL61 HEK-293T C370(0.97)  LDD1656  [5]
 LDCM0454  CL62 HEK-293T C370(1.08); C238(0.99)  LDD1657  [5]
 LDCM0455  CL63 HEK-293T C238(1.10)  LDD1658  [5]
 LDCM0456  CL64 HEK-293T C370(1.13); C238(0.98)  LDD1659  [5]
 LDCM0458  CL66 HEK-293T C370(1.02)  LDD1661  [5]
 LDCM0459  CL67 HEK-293T C370(1.11)  LDD1662  [5]
 LDCM0460  CL68 HEK-293T C370(1.15)  LDD1663  [5]
 LDCM0461  CL69 HEK-293T C370(1.07); C420(0.95)  LDD1664  [5]
 LDCM0462  CL7 HEK-293T C370(0.94)  LDD1665  [5]
 LDCM0463  CL70 HEK-293T C370(1.05)  LDD1666  [5]
 LDCM0464  CL71 HEK-293T C370(1.06)  LDD1667  [5]
 LDCM0465  CL72 HEK-293T C370(0.99)  LDD1668  [5]
 LDCM0466  CL73 HEK-293T C370(0.92)  LDD1669  [5]
 LDCM0467  CL74 HEK-293T C370(1.09); C238(0.97)  LDD1670  [5]
 LDCM0469  CL76 HEK-293T C370(0.99); C238(1.09)  LDD1672  [5]
 LDCM0471  CL78 HEK-293T C370(1.09)  LDD1674  [5]
 LDCM0472  CL79 HEK-293T C370(1.05)  LDD1675  [5]
 LDCM0473  CL8 HEK-293T C370(1.18)  LDD1676  [5]
 LDCM0474  CL80 HEK-293T C370(0.99)  LDD1677  [5]
 LDCM0475  CL81 HEK-293T C370(1.18); C420(1.02)  LDD1678  [5]
 LDCM0476  CL82 HEK-293T C370(1.09)  LDD1679  [5]
 LDCM0477  CL83 HEK-293T C370(1.13)  LDD1680  [5]
 LDCM0478  CL84 HEK-293T C370(0.97)  LDD1681  [5]
 LDCM0479  CL85 HEK-293T C370(1.10)  LDD1682  [5]
 LDCM0480  CL86 HEK-293T C370(1.12); C238(0.89)  LDD1683  [5]
 LDCM0481  CL87 HEK-293T C238(0.81)  LDD1684  [5]
 LDCM0482  CL88 HEK-293T C370(1.04); C238(0.82)  LDD1685  [5]
 LDCM0484  CL9 HEK-293T C370(1.08); C420(0.97)  LDD1687  [5]
 LDCM0485  CL90 HEK-293T C370(1.16)  LDD1688  [5]
 LDCM0486  CL91 HEK-293T C370(1.37)  LDD1689  [5]
 LDCM0487  CL92 HEK-293T C370(1.14)  LDD1690  [5]
 LDCM0488  CL93 HEK-293T C370(1.29); C420(0.97)  LDD1691  [5]
 LDCM0489  CL94 HEK-293T C370(1.27)  LDD1692  [5]
 LDCM0490  CL95 HEK-293T C370(1.27)  LDD1693  [5]
 LDCM0491  CL96 HEK-293T C370(0.95)  LDD1694  [5]
 LDCM0492  CL97 HEK-293T C370(1.13)  LDD1695  [5]
 LDCM0493  CL98 HEK-293T C370(1.13); C238(1.14)  LDD1696  [5]
 LDCM0494  CL99 HEK-293T C238(1.03)  LDD1697  [5]
 LDCM0495  E2913 HEK-293T C238(0.89)  LDD1698  [5]
 LDCM0625  F8 Ramos C238(0.43); C328(0.57)  LDD2187  [6]
 LDCM0572  Fragment10 Ramos C238(2.12); C328(2.32)  LDD2189  [6]
 LDCM0573  Fragment11 Ramos C238(5.71)  LDD2190  [6]
 LDCM0574  Fragment12 Ramos C238(1.04); C328(1.26)  LDD2191  [6]
 LDCM0575  Fragment13 Ramos C238(0.95); C328(1.00)  LDD2192  [6]
 LDCM0576  Fragment14 Ramos C238(0.46); C328(0.29)  LDD2193  [6]
 LDCM0579  Fragment20 Ramos C238(1.21); C328(1.44)  LDD2194  [6]
 LDCM0580  Fragment21 Ramos C238(1.10); C328(1.22)  LDD2195  [6]
 LDCM0582  Fragment23 Ramos C238(1.41); C328(1.86)  LDD2196  [6]
 LDCM0578  Fragment27 Ramos C238(0.97); C328(1.20)  LDD2197  [6]
 LDCM0586  Fragment28 Ramos C238(0.73); C328(0.78)  LDD2198  [6]
 LDCM0588  Fragment30 Ramos C238(1.14); C328(1.70)  LDD2199  [6]
 LDCM0589  Fragment31 Ramos C238(1.32); C328(1.26)  LDD2200  [6]
 LDCM0590  Fragment32 Ramos C238(1.56); C328(4.03)  LDD2201  [6]
 LDCM0468  Fragment33 HEK-293T C238(0.94)  LDD1671  [5]
 LDCM0596  Fragment38 Ramos C238(1.06); C328(1.46)  LDD2203  [6]
 LDCM0566  Fragment4 Ramos C238(0.57); C328(0.93)  LDD2184  [6]
 LDCM0427  Fragment51 HEK-293T C370(1.05); C238(1.19)  LDD1631  [5]
 LDCM0610  Fragment52 Ramos C238(1.21); C328(1.50)  LDD2204  [6]
 LDCM0614  Fragment56 Ramos C238(1.20); C328(1.24)  LDD2205  [6]
 LDCM0569  Fragment7 Ramos C238(1.04); C328(2.68)  LDD2186  [6]
 LDCM0571  Fragment9 Ramos C238(2.05); C328(3.16)  LDD2188  [6]
 LDCM0022  KB02 T cell-activated C670, C676(8.11); C370(20.00); C340(10.10); C238(5.07)  LDD1704  [2]
 LDCM0023  KB03 Ramos C238(1.00); C328(1.10)  LDD2183  [6]
 LDCM0024  KB05 NALM-6 C370(3.71)  LDD3339  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 9 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
26S proteasome regulatory subunit 8 (PSMC5) AAA ATPase family P62195
Histone-lysine N-methyltransferase SMYD1 (SMYD1) Class V-like SAM-binding methyltransferase superfamily Q8NB12
Phenylalanine--tRNA ligase, mitochondrial (FARS2) Class-II aminoacyl-tRNA synthetase family O95363
Ribonuclease P protein subunit p25 (RPP25) Histone-like Alba family Q9BUL9
Histone acetyltransferase KAT5 (KAT5) MYST (SAS/MOZ) family Q92993
Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 (ENPP7) Nucleotide pyrophosphatase/phosphodiesterase family Q6UWV6
Cathepsin Z (CTSZ) Peptidase C1 family Q9UBR2
TNF receptor-associated factor 4 (TRAF4) TNF receptor-associated factor family Q9BUZ4
Tripartite motif-containing protein 42 (TRIM42) TRIM/RBCC family Q8IWZ5
Transporter and channel
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
AP-1 complex subunit mu-1 (AP1M1) Adaptor complexes medium subunit family Q9BXS5
Nuclear RNA export factor 1 (NXF1) NXF family Q9UBU9
Large neutral amino acids transporter small subunit 3 (SLC43A1) SLC43A transporter (TC 2.A.1.44) family O75387
Sodium channel modifier 1 (SCNM1) . Q9BWG6
Transcription factor
Click To Hide/Show 13 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Basic leucine zipper transcriptional factor ATF-like 3 (BATF3) BZIP family Q9NR55
Fos-related antigen 2 (FOSL2) BZIP family P15408
Transcription factor MafF (MAFF) BZIP family Q9ULX9
Transcription factor MafG (MAFG) BZIP family O15525
Transcription factor MafK (MAFK) BZIP family O60675
Zinc finger and BTB domain-containing protein 24 (ZBTB24) Krueppel C2H2-type zinc-finger protein family O43167
Zinc finger protein 124 (ZNF124) Krueppel C2H2-type zinc-finger protein family Q15973
Zinc finger protein 438 (ZNF438) Krueppel C2H2-type zinc-finger protein family Q7Z4V0
Zinc finger protein 774 (ZNF774) Krueppel C2H2-type zinc-finger protein family Q6NX45
Zinc finger protein 792 (ZNF792) Krueppel C2H2-type zinc-finger protein family Q3KQV3
Teashirt homolog 2 (TSHZ2) Teashirt C2H2-type zinc-finger protein family Q9NRE2
High mobility group protein 20A (HMG20A) . Q9NP66
Zinc finger and BTB domain-containing protein 34 (ZBTB34) . Q8NCN2
Other
Click To Hide/Show 15 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Centromere protein P (CENPP) CENP-P/CTF19 family Q6IPU0
Cilia- and flagella-associated protein 58 (CFAP58) CFAP58 family Q5T655
CWF19-like protein 2 (CWF19L2) CWF19 family Q2TBE0
Protein FAM161A (FAM161A) FAM161 family Q3B820
Inhibitory synaptic factor 2A (INSYN2A) INSYN2 family Q6ZSG2
Transcription elongation factor A protein 2 (TCEA2) TFS-II family Q15560
Tubby-related protein 3 (TULP3) TUB family O75386
Large ribosomal subunit protein uL6 (RPL9; RPL9P7; RPL9P8; RPL9P9) Universal ribosomal protein uL6 family P32969
Ankyrin repeat domain-containing protein 55 (ANKRD55) . Q3KP44
Bromo adjacent homology domain-containing 1 protein (BAHD1) . Q8TBE0
Chromobox protein homolog 8 (CBX8) . Q9HC52
Coiled-coil domain-containing protein 185 (CCDC185) . Q8N715
Elongin-A (ELOA) . Q14241
Leucine zipper protein 4 (LUZP4) . Q9P127
Microspherule protein 1 (MCRS1) . Q96EZ8

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
2 An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells. Cell. 2020 Aug 20;182(4):1009-1026.e29. doi: 10.1016/j.cell.2020.07.001. Epub 2020 Jul 29.
3 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
4 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
5 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
6 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578