Details of the Target

General Information of Target

Target ID LDTP10704
Target Name Protein FAM193B (FAM193B)
Gene Name FAM193B
Synonyms
IRIZIO; KIAA1931; Protein FAM193B
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MAANVGDQRSTDWSSQYSMVAGAGRENGMETPMHENPEWEKARQALASISKSGAAGGSAK
SSSNGPVASAQYVSQAEASALQQQQYYQWYQQYNYAYPYSYYYPMSMYQSYGSPSQYGMA
GSYGSATPQQPSAPQHQGTLNQPPVPGMDESMSYQAPPQQLPSAQPPQPSNPPHGAHTLN
SGPQPGTAPATQHSQAGPATGQAYGPHTYTEPAKPKKGQQLWNRMKPAPGTGGLKFNIQK
RPFAVTTQSFGSNAEGQHSGFGPQPNPEKVQNHSGSSARGNLSGKPDDWPQDMKEYVERC
FTACESEEDKDRTEKLLKEVLQARLQDGSAYTIDWSREPLPGLTREPVAESPKKKRWEAA
SSLHPPRGAGSATRGGGAPSQRGTPGAGGAGRARGNSFTKFGNRNVFMKDNSSSSSTDSR
SRSSSRSPTRHFRRSDSHSDSDSSYSGNECHPVGRRNPPPKGRGGRGAHMDRGRGRAQRG
KRHDLAPTKRSRKKMAALECEDPERELKKQKRAARFQHGHSRRLRLEPLVLQMSSLESSG
ADPDWQELQIVGTCPDITKHYLRLTCAPDPSTVRPVAVLKKSLCMVKCHWKEKQDYAFAC
EQMKSIRQDLTVQGIRTEFTVEVYETHARIALEKGDHEEFNQCQTQLKSLYAENLPGNVG
EFTAYRILYYIFTKNSGDITTELAYLTRELKADPCVAHALALRTAWALGNYHRFFRLYCH
APCMSGYLVDKFADRERKVALKAMIKTFRPALPVSYLQAELAFEGEAACRAFLEPLGLAY
TGPDNSSIDCRLSLAQLSAF
Target Bioclass
Other
Family
FAM193 family
Subcellular location
Cytoplasm
Uniprot ID
Q96PV7
Ensemble ID
ENST00000514747.6
HGNC ID
HGNC:25524

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 8 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C130(1.62); C133(1.62)  LDD0080  [1]
CY-1
 Probe Info  		E839(0.00); Q838(0.00)  LDD0246  [2]
IA-alkyne
 Probe Info  		C766(0.00); C400(0.00)  LDD0165  [3]
NAIA_4
 Probe Info  		N.A.  LDD2226  [4]
ENE
 Probe Info  		N.A.  LDD0006  [5]
IPM
 Probe Info  		N.A.  LDD0147  [6]
Phosphinate-6
 Probe Info  		C766(0.00); C700(0.00)  LDD0018  [7]
NAIA_5
 Probe Info  		N.A.  LDD2223  [4]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C766(0.98)  LDD1507  [8]
 LDCM0215  AC10 HEK-293T C375(1.63); C381(1.63)  LDD0813  [1]
 LDCM0226  AC11 HEK-293T C375(1.32); C381(1.32)  LDD0824  [1]
 LDCM0230  AC113 HEK-293T C375(1.39); C381(1.39)  LDD0828  [1]
 LDCM0231  AC114 HEK-293T C375(1.00); C381(1.00)  LDD0829  [1]
 LDCM0232  AC115 HEK-293T C375(1.01); C381(1.01)  LDD0830  [1]
 LDCM0233  AC116 HEK-293T C375(0.93); C381(0.93)  LDD0831  [1]
 LDCM0234  AC117 HEK-293T C375(1.15); C381(1.15)  LDD0832  [1]
 LDCM0235  AC118 HEK-293T C375(0.89); C381(0.89)  LDD0833  [1]
 LDCM0236  AC119 HEK-293T C375(1.11); C381(1.11)  LDD0834  [1]
 LDCM0237  AC12 HEK-293T C375(1.53); C381(1.53)  LDD0835  [1]
 LDCM0238  AC120 HEK-293T C375(3.52); C381(3.52)  LDD0836  [1]
 LDCM0239  AC121 HEK-293T C375(1.46); C381(1.46)  LDD0837  [1]
 LDCM0240  AC122 HEK-293T C375(1.11); C381(1.11)  LDD0838  [1]
 LDCM0241  AC123 HEK-293T C375(1.11); C381(1.11)  LDD0839  [1]
 LDCM0242  AC124 HEK-293T C375(1.45); C381(1.45)  LDD0840  [1]
 LDCM0243  AC125 HEK-293T C375(1.43); C381(1.43)  LDD0841  [1]
 LDCM0244  AC126 HEK-293T C375(1.55); C381(1.55)  LDD0842  [1]
 LDCM0245  AC127 HEK-293T C375(1.36); C381(1.36)  LDD0843  [1]
 LDCM0259  AC14 HEK-293T C375(1.63); C381(1.63)  LDD0857  [1]
 LDCM0263  AC143 HEK-293T C375(0.81); C381(0.81)  LDD0861  [1]
 LDCM0264  AC144 HEK-293T C375(0.92); C381(0.92)  LDD0862  [1]
 LDCM0265  AC145 HEK-293T C375(1.10); C381(1.10)  LDD0863  [1]
 LDCM0266  AC146 HEK-293T C375(1.04); C381(1.04)  LDD0864  [1]
 LDCM0267  AC147 HEK-293T C375(0.70); C381(0.70)  LDD0865  [1]
 LDCM0268  AC148 HEK-293T C375(0.94); C381(0.94)  LDD0866  [1]
 LDCM0269  AC149 HEK-293T C375(1.36); C381(1.36)  LDD0867  [1]
 LDCM0270  AC15 HEK-293T C375(1.47); C381(1.47)  LDD0868  [1]
 LDCM0271  AC150 HEK-293T C375(0.89); C381(0.89)  LDD0869  [1]
 LDCM0272  AC151 HEK-293T C375(1.19); C381(1.19)  LDD0870  [1]
 LDCM0273  AC152 HEK-293T C375(0.93); C381(0.93)  LDD0871  [1]
 LDCM0274  AC153 HEK-293T C375(0.96); C381(0.96)  LDD0872  [1]
 LDCM0621  AC154 HEK-293T C375(0.82); C381(0.82)  LDD2162  [1]
 LDCM0622  AC155 HEK-293T C375(1.30); C381(1.30)  LDD2163  [1]
 LDCM0623  AC156 HEK-293T C375(1.08); C381(1.08)  LDD2164  [1]
 LDCM0624  AC157 HEK-293T C375(0.83); C381(0.83)  LDD2165  [1]
 LDCM0276  AC17 HEK-293T C766(1.07)  LDD1515  [8]
 LDCM0277  AC18 HEK-293T C766(0.93); C873(0.97)  LDD1516  [8]
 LDCM0278  AC19 HEK-293T C766(1.40); C873(1.14)  LDD1517  [8]
 LDCM0279  AC2 HEK-293T C766(0.95); C873(0.99)  LDD1518  [8]
 LDCM0280  AC20 HEK-293T C766(1.08); C873(0.97)  LDD1519  [8]
 LDCM0281  AC21 HEK-293T C766(1.04); C873(0.96)  LDD1520  [8]
 LDCM0282  AC22 HEK-293T C766(1.01); C873(0.99)  LDD1521  [8]
 LDCM0283  AC23 HEK-293T C766(1.04); C873(0.93)  LDD1522  [8]
 LDCM0284  AC24 HEK-293T C766(0.94); C873(0.90)  LDD1523  [8]
 LDCM0285  AC25 HEK-293T C375(0.81); C381(0.59)  LDD0883  [1]
 LDCM0286  AC26 HEK-293T C375(0.67); C381(0.79)  LDD0884  [1]
 LDCM0287  AC27 HEK-293T C375(0.67); C381(0.82)  LDD0885  [1]
 LDCM0288  AC28 HEK-293T C375(0.85); C381(0.63)  LDD0886  [1]
 LDCM0289  AC29 HEK-293T C375(0.71); C381(0.72)  LDD0887  [1]
 LDCM0290  AC3 HEK-293T C766(1.00); C873(0.99)  LDD1529  [8]
 LDCM0291  AC30 HEK-293T C375(0.74); C381(0.63)  LDD0889  [1]
 LDCM0292  AC31 HEK-293T C375(0.71); C381(0.62)  LDD0890  [1]
 LDCM0293  AC32 HEK-293T C375(0.77); C381(0.81)  LDD0891  [1]
 LDCM0294  AC33 HEK-293T C375(0.86); C381(0.78)  LDD0892  [1]
 LDCM0295  AC34 HEK-293T C375(0.81); C381(0.70)  LDD0893  [1]
 LDCM0296  AC35 HEK-293T C375(1.47); C381(1.47)  LDD0894  [1]
 LDCM0297  AC36 HEK-293T C375(0.56); C381(0.56)  LDD0895  [1]
 LDCM0298  AC37 HEK-293T C375(0.81); C381(0.81)  LDD0896  [1]
 LDCM0299  AC38 HEK-293T C375(1.00); C381(1.00)  LDD0897  [1]
 LDCM0300  AC39 HEK-293T C375(1.15); C381(1.15)  LDD0898  [1]
 LDCM0301  AC4 HEK-293T C766(1.01); C873(0.97)  LDD1540  [8]
 LDCM0302  AC40 HEK-293T C375(1.13); C381(1.13)  LDD0900  [1]
 LDCM0303  AC41 HEK-293T C375(0.90); C381(0.90)  LDD0901  [1]
 LDCM0304  AC42 HEK-293T C375(0.90); C381(0.90)  LDD0902  [1]
 LDCM0305  AC43 HEK-293T C375(1.05); C381(1.05)  LDD0903  [1]
 LDCM0306  AC44 HEK-293T C375(0.85); C381(0.85)  LDD0904  [1]
 LDCM0307  AC45 HEK-293T C375(0.94); C381(0.94)  LDD0905  [1]
 LDCM0308  AC46 HEK-293T C766(0.89); C873(0.98)  LDD1547  [8]
 LDCM0309  AC47 HEK-293T C766(1.02); C873(0.97)  LDD1548  [8]
 LDCM0310  AC48 HEK-293T C766(0.90); C873(0.94)  LDD1549  [8]
 LDCM0311  AC49 HEK-293T C766(1.06)  LDD1550  [8]
 LDCM0312  AC5 HEK-293T C766(1.00); C873(0.95)  LDD1551  [8]
 LDCM0313  AC50 HEK-293T C766(0.93); C873(0.90)  LDD1552  [8]
 LDCM0314  AC51 HEK-293T C766(1.03); C873(1.03)  LDD1553  [8]
 LDCM0315  AC52 HEK-293T C766(1.18); C873(0.94)  LDD1554  [8]
 LDCM0316  AC53 HEK-293T C766(1.05); C873(0.95)  LDD1555  [8]
 LDCM0317  AC54 HEK-293T C766(0.91); C873(1.03)  LDD1556  [8]
 LDCM0318  AC55 HEK-293T C766(1.04); C873(0.98)  LDD1557  [8]
 LDCM0319  AC56 HEK-293T C766(1.05); C873(0.95)  LDD1558  [8]
 LDCM0320  AC57 HEK-293T C375(1.05); C381(1.05)  LDD0918  [1]
 LDCM0321  AC58 HEK-293T C375(1.14); C381(1.14)  LDD0919  [1]
 LDCM0322  AC59 HEK-293T C375(1.00); C381(1.00)  LDD0920  [1]
 LDCM0323  AC6 HEK-293T C375(1.10); C381(1.10)  LDD0921  [1]
 LDCM0324  AC60 HEK-293T C375(1.16); C381(1.16)  LDD0922  [1]
 LDCM0325  AC61 HEK-293T C375(0.92); C381(0.92)  LDD0923  [1]
 LDCM0326  AC62 HEK-293T C375(0.82); C381(0.82)  LDD0924  [1]
 LDCM0327  AC63 HEK-293T C375(1.06); C381(1.06)  LDD0925  [1]
 LDCM0328  AC64 HEK-293T C375(0.98); C381(0.98)  LDD0926  [1]
 LDCM0329  AC65 HEK-293T C375(1.19); C381(1.19)  LDD0927  [1]
 LDCM0330  AC66 HEK-293T C375(0.93); C381(0.93)  LDD0928  [1]
 LDCM0331  AC67 HEK-293T C375(1.13); C381(1.13)  LDD0929  [1]
 LDCM0332  AC68 HEK-293T C375(0.97); C381(0.97)  LDD0930  [1]
 LDCM0333  AC69 HEK-293T C375(1.10); C381(1.10)  LDD0931  [1]
 LDCM0334  AC7 HEK-293T C375(0.96); C381(0.96)  LDD0932  [1]
 LDCM0335  AC70 HEK-293T C375(0.98); C381(0.98)  LDD0933  [1]
 LDCM0336  AC71 HEK-293T C375(1.07); C381(1.07)  LDD0934  [1]
 LDCM0337  AC72 HEK-293T C375(1.08); C381(1.08)  LDD0935  [1]
 LDCM0338  AC73 HEK-293T C375(1.12); C381(1.12)  LDD0936  [1]
 LDCM0339  AC74 HEK-293T C375(0.97); C381(0.97)  LDD0937  [1]
 LDCM0340  AC75 HEK-293T C375(1.02); C381(1.02)  LDD0938  [1]
 LDCM0341  AC76 HEK-293T C375(0.87); C381(0.87)  LDD0939  [1]
 LDCM0342  AC77 HEK-293T C375(1.02); C381(1.02)  LDD0940  [1]
 LDCM0343  AC78 HEK-293T C375(1.24); C381(1.24)  LDD0941  [1]
 LDCM0344  AC79 HEK-293T C375(1.24); C381(1.24)  LDD0942  [1]
 LDCM0345  AC8 HEK-293T C375(0.91); C381(0.91)  LDD0943  [1]
 LDCM0346  AC80 HEK-293T C375(1.11); C381(1.11)  LDD0944  [1]
 LDCM0347  AC81 HEK-293T C375(1.09); C381(1.09)  LDD0945  [1]
 LDCM0348  AC82 HEK-293T C375(1.18); C381(1.18)  LDD0946  [1]
 LDCM0349  AC83 HEK-293T C375(1.08); C381(1.28)  LDD0947  [1]
 LDCM0350  AC84 HEK-293T C375(0.85); C381(1.04)  LDD0948  [1]
 LDCM0351  AC85 HEK-293T C375(1.09); C381(1.03)  LDD0949  [1]
 LDCM0352  AC86 HEK-293T C375(1.74); C381(1.22)  LDD0950  [1]
 LDCM0353  AC87 HEK-293T C375(1.13); C381(1.00)  LDD0951  [1]
 LDCM0354  AC88 HEK-293T C375(1.15); C381(1.19)  LDD0952  [1]
 LDCM0355  AC89 HEK-293T C375(1.45); C381(1.12)  LDD0953  [1]
 LDCM0357  AC90 HEK-293T C375(1.29); C381(1.19)  LDD0955  [1]
 LDCM0358  AC91 HEK-293T C375(1.01); C381(1.29)  LDD0956  [1]
 LDCM0359  AC92 HEK-293T C375(1.00); C381(1.01)  LDD0957  [1]
 LDCM0360  AC93 HEK-293T C375(1.00); C381(1.03)  LDD0958  [1]
 LDCM0361  AC94 HEK-293T C375(1.19); C381(1.02)  LDD0959  [1]
 LDCM0362  AC95 HEK-293T C375(0.86); C381(1.30)  LDD0960  [1]
 LDCM0363  AC96 HEK-293T C375(1.47); C381(1.31)  LDD0961  [1]
 LDCM0364  AC97 HEK-293T C375(0.95); C381(1.23)  LDD0962  [1]
 LDCM0248  AKOS034007472 HEK-293T C375(1.38); C381(1.38)  LDD0846  [1]
 LDCM0356  AKOS034007680 HEK-293T C375(1.30); C381(1.30)  LDD0954  [1]
 LDCM0275  AKOS034007705 HEK-293T C375(1.88); C381(1.88)  LDD0873  [1]
 LDCM0020  ARS-1620 HCC44 C130(1.20); C133(1.20)  LDD2171  [1]
 LDCM0632  CL-Sc Hep-G2 C400(0.90)  LDD2227  [4]
 LDCM0367  CL1 HEK-293T C766(0.98); C400(0.97)  LDD1571  [8]
 LDCM0368  CL10 HEK-293T C766(0.97); C873(1.15)  LDD1572  [8]
 LDCM0369  CL100 HEK-293T C766(1.08)  LDD1573  [8]
 LDCM0370  CL101 HEK-293T C375(0.95); C381(0.95)  LDD0968  [1]
 LDCM0371  CL102 HEK-293T C375(1.16); C381(1.16)  LDD0969  [1]
 LDCM0372  CL103 HEK-293T C375(1.76); C381(1.76)  LDD0970  [1]
 LDCM0373  CL104 HEK-293T C375(0.92); C381(0.92)  LDD0971  [1]
 LDCM0374  CL105 HEK-293T C766(0.98); C400(0.99)  LDD1578  [8]
 LDCM0375  CL106 HEK-293T C766(0.99); C873(1.06)  LDD1579  [8]
 LDCM0376  CL107 HEK-293T C766(0.94); C873(0.83); C573(0.91)  LDD1580  [8]
 LDCM0377  CL108 HEK-293T C766(1.00)  LDD1581  [8]
 LDCM0378  CL109 HEK-293T C766(1.02); C400(0.96)  LDD1582  [8]
 LDCM0379  CL11 HEK-293T C766(1.02); C873(1.02)  LDD1583  [8]
 LDCM0380  CL110 HEK-293T C766(0.97); C873(0.95)  LDD1584  [8]
 LDCM0381  CL111 HEK-293T C766(0.92); C873(0.84); C573(0.94)  LDD1585  [8]
 LDCM0382  CL112 HEK-293T C375(0.62); C381(0.65)  LDD0980  [1]
 LDCM0383  CL113 HEK-293T C375(0.67); C381(0.66)  LDD0981  [1]
 LDCM0384  CL114 HEK-293T C375(0.62); C381(0.52)  LDD0982  [1]
 LDCM0385  CL115 HEK-293T C375(0.81); C381(0.78)  LDD0983  [1]
 LDCM0386  CL116 HEK-293T C375(0.72); C381(0.55)  LDD0984  [1]
 LDCM0387  CL117 HEK-293T C375(1.27); C381(1.27)  LDD0985  [1]
 LDCM0388  CL118 HEK-293T C375(0.73); C381(0.73)  LDD0986  [1]
 LDCM0389  CL119 HEK-293T C375(0.72); C381(0.72)  LDD0987  [1]
 LDCM0390  CL12 HEK-293T C766(0.95); C873(0.69)  LDD1594  [8]
 LDCM0391  CL120 HEK-293T C375(0.73); C381(0.73)  LDD0989  [1]
 LDCM0392  CL121 HEK-293T C766(1.08); C400(0.82)  LDD1596  [8]
 LDCM0393  CL122 HEK-293T C766(0.94); C873(0.96)  LDD1597  [8]
 LDCM0394  CL123 HEK-293T C766(0.85); C873(0.85); C573(0.95)  LDD1598  [8]
 LDCM0395  CL124 HEK-293T C766(1.01)  LDD1599  [8]
 LDCM0396  CL125 HEK-293T C375(1.38); C381(1.38)  LDD0994  [1]
 LDCM0397  CL126 HEK-293T C375(1.11); C381(1.11)  LDD0995  [1]
 LDCM0398  CL127 HEK-293T C375(1.14); C381(1.14)  LDD0996  [1]
 LDCM0399  CL128 HEK-293T C375(1.20); C381(1.20)  LDD0997  [1]
 LDCM0400  CL13 HEK-293T C766(1.10); C400(0.96)  LDD1604  [8]
 LDCM0401  CL14 HEK-293T C766(0.96); C873(0.93)  LDD1605  [8]
 LDCM0402  CL15 HEK-293T C766(0.85); C873(0.79); C573(1.13)  LDD1606  [8]
 LDCM0403  CL16 HEK-293T C766(1.03)  LDD1607  [8]
 LDCM0404  CL17 HEK-293T C766(0.95)  LDD1608  [8]
 LDCM0405  CL18 HEK-293T C766(1.03); C873(0.75)  LDD1609  [8]
 LDCM0406  CL19 HEK-293T C766(1.00); C873(0.84)  LDD1610  [8]
 LDCM0407  CL2 HEK-293T C766(0.93); C873(0.95)  LDD1611  [8]
 LDCM0408  CL20 HEK-293T C766(1.16); C873(0.89)  LDD1612  [8]
 LDCM0409  CL21 HEK-293T C766(0.93); C873(0.71)  LDD1613  [8]
 LDCM0410  CL22 HEK-293T C766(1.04); C873(1.04)  LDD1614  [8]
 LDCM0411  CL23 HEK-293T C766(1.11); C873(1.08)  LDD1615  [8]
 LDCM0412  CL24 HEK-293T C766(0.86); C873(0.68)  LDD1616  [8]
 LDCM0413  CL25 HEK-293T C766(0.94); C400(0.91)  LDD1617  [8]
 LDCM0414  CL26 HEK-293T C766(0.99); C873(1.04)  LDD1618  [8]
 LDCM0415  CL27 HEK-293T C766(0.93); C873(0.92); C573(0.92)  LDD1619  [8]
 LDCM0416  CL28 HEK-293T C766(0.99)  LDD1620  [8]
 LDCM0417  CL29 HEK-293T C766(0.97)  LDD1621  [8]
 LDCM0418  CL3 HEK-293T C766(0.88); C873(0.90); C573(0.95)  LDD1622  [8]
 LDCM0419  CL30 HEK-293T C766(1.00); C873(0.88)  LDD1623  [8]
 LDCM0420  CL31 HEK-293T C375(1.09); C381(1.09)  LDD1018  [1]
 LDCM0421  CL32 HEK-293T C375(0.75); C381(0.75)  LDD1019  [1]
 LDCM0422  CL33 HEK-293T C375(0.96); C381(0.96)  LDD1020  [1]
 LDCM0423  CL34 HEK-293T C375(0.82); C381(0.82)  LDD1021  [1]
 LDCM0424  CL35 HEK-293T C375(0.96); C381(0.96)  LDD1022  [1]
 LDCM0425  CL36 HEK-293T C375(0.73); C381(0.73)  LDD1023  [1]
 LDCM0426  CL37 HEK-293T C375(1.09); C381(1.09)  LDD1024  [1]
 LDCM0428  CL39 HEK-293T C375(0.74); C381(0.74)  LDD1026  [1]
 LDCM0429  CL4 HEK-293T C766(0.88)  LDD1633  [8]
 LDCM0430  CL40 HEK-293T C375(0.78); C381(0.78)  LDD1028  [1]
 LDCM0431  CL41 HEK-293T C375(0.86); C381(0.86)  LDD1029  [1]
 LDCM0432  CL42 HEK-293T C375(1.04); C381(1.04)  LDD1030  [1]
 LDCM0433  CL43 HEK-293T C375(0.72); C381(0.72)  LDD1031  [1]
 LDCM0434  CL44 HEK-293T C375(0.97); C381(0.97)  LDD1032  [1]
 LDCM0435  CL45 HEK-293T C375(0.64); C381(0.64)  LDD1033  [1]
 LDCM0436  CL46 HEK-293T C766(1.00); C873(0.95)  LDD1640  [8]
 LDCM0437  CL47 HEK-293T C766(1.01); C873(0.99)  LDD1641  [8]
 LDCM0438  CL48 HEK-293T C766(0.93); C873(0.74)  LDD1642  [8]
 LDCM0439  CL49 HEK-293T C766(1.04); C400(0.81)  LDD1643  [8]
 LDCM0440  CL5 HEK-293T C766(0.94)  LDD1644  [8]
 LDCM0441  CL50 HEK-293T C766(0.92); C873(0.93)  LDD1645  [8]
 LDCM0443  CL52 HEK-293T C766(1.11)  LDD1646  [8]
 LDCM0444  CL53 HEK-293T C766(1.00)  LDD1647  [8]
 LDCM0445  CL54 HEK-293T C766(0.91); C873(0.78)  LDD1648  [8]
 LDCM0446  CL55 HEK-293T C766(0.97); C873(0.91)  LDD1649  [8]
 LDCM0447  CL56 HEK-293T C766(1.04); C873(0.84)  LDD1650  [8]
 LDCM0448  CL57 HEK-293T C766(1.09); C873(0.96)  LDD1651  [8]
 LDCM0449  CL58 HEK-293T C766(0.85); C873(0.96)  LDD1652  [8]
 LDCM0450  CL59 HEK-293T C766(0.94); C873(1.04)  LDD1653  [8]
 LDCM0451  CL6 HEK-293T C766(0.92); C873(0.87)  LDD1654  [8]
 LDCM0452  CL60 HEK-293T C766(1.02); C873(0.74)  LDD1655  [8]
 LDCM0453  CL61 HEK-293T C766(1.01); C400(0.81)  LDD1656  [8]
 LDCM0454  CL62 HEK-293T C766(0.97); C873(0.95)  LDD1657  [8]
 LDCM0455  CL63 HEK-293T C766(0.96); C873(0.89); C573(0.98)  LDD1658  [8]
 LDCM0456  CL64 HEK-293T C766(0.95)  LDD1659  [8]
 LDCM0457  CL65 HEK-293T C766(1.00)  LDD1660  [8]
 LDCM0458  CL66 HEK-293T C766(0.96); C873(0.95)  LDD1661  [8]
 LDCM0459  CL67 HEK-293T C766(1.00); C873(0.89)  LDD1662  [8]
 LDCM0460  CL68 HEK-293T C766(1.10); C873(0.77)  LDD1663  [8]
 LDCM0461  CL69 HEK-293T C766(0.95); C873(0.77)  LDD1664  [8]
 LDCM0462  CL7 HEK-293T C766(1.01); C873(0.84)  LDD1665  [8]
 LDCM0463  CL70 HEK-293T C766(1.01); C873(1.04)  LDD1666  [8]
 LDCM0464  CL71 HEK-293T C766(0.94); C873(1.04)  LDD1667  [8]
 LDCM0465  CL72 HEK-293T C766(0.95); C873(0.72)  LDD1668  [8]
 LDCM0466  CL73 HEK-293T C766(0.99); C400(0.79)  LDD1669  [8]
 LDCM0467  CL74 HEK-293T C766(0.94); C873(0.97)  LDD1670  [8]
 LDCM0469  CL76 HEK-293T C375(1.20); C381(1.20)  LDD1067  [1]
 LDCM0470  CL77 HEK-293T C375(1.58); C381(1.58)  LDD1068  [1]
 LDCM0471  CL78 HEK-293T C375(1.26); C381(1.26)  LDD1069  [1]
 LDCM0472  CL79 HEK-293T C375(1.09); C381(1.09)  LDD1070  [1]
 LDCM0473  CL8 HEK-293T C766(1.06); C873(0.91)  LDD1676  [8]
 LDCM0474  CL80 HEK-293T C375(1.48); C381(1.48)  LDD1072  [1]
 LDCM0475  CL81 HEK-293T C375(1.18); C381(1.18)  LDD1073  [1]
 LDCM0476  CL82 HEK-293T C375(1.38); C381(1.38)  LDD1074  [1]
 LDCM0477  CL83 HEK-293T C375(1.33); C381(1.33)  LDD1075  [1]
 LDCM0478  CL84 HEK-293T C375(1.49); C381(1.49)  LDD1076  [1]
 LDCM0479  CL85 HEK-293T C375(1.43); C381(1.43)  LDD1077  [1]
 LDCM0480  CL86 HEK-293T C375(1.46); C381(1.46)  LDD1078  [1]
 LDCM0481  CL87 HEK-293T C375(1.20); C381(1.20)  LDD1079  [1]
 LDCM0482  CL88 HEK-293T C375(1.84); C381(1.84)  LDD1080  [1]
 LDCM0483  CL89 HEK-293T C375(1.64); C381(1.64)  LDD1081  [1]
 LDCM0484  CL9 HEK-293T C766(1.00); C873(0.74)  LDD1687  [8]
 LDCM0485  CL90 HEK-293T C375(1.58); C381(1.58)  LDD1083  [1]
 LDCM0486  CL91 HEK-293T C766(1.01); C873(1.03)  LDD1689  [8]
 LDCM0487  CL92 HEK-293T C766(1.17); C873(0.84)  LDD1690  [8]
 LDCM0488  CL93 HEK-293T C766(0.92); C873(0.89)  LDD1691  [8]
 LDCM0489  CL94 HEK-293T C766(1.05); C873(0.94)  LDD1692  [8]
 LDCM0490  CL95 HEK-293T C766(1.03); C873(1.06)  LDD1693  [8]
 LDCM0491  CL96 HEK-293T C766(1.01); C873(1.19)  LDD1694  [8]
 LDCM0492  CL97 HEK-293T C766(1.09); C400(1.00)  LDD1695  [8]
 LDCM0493  CL98 HEK-293T C766(0.88); C873(0.96)  LDD1696  [8]
 LDCM0494  CL99 HEK-293T C766(0.92); C873(0.94); C573(0.92)  LDD1697  [8]
 LDCM0495  E2913 HEK-293T C766(0.95); C873(0.84); C573(0.82)  LDD1698  [8]
 LDCM0468  Fragment33 HEK-293T C766(0.96); C873(0.82); C573(0.94)  LDD1671  [8]
 LDCM0427  Fragment51 HEK-293T C375(0.73); C381(0.73)  LDD1025  [1]
 LDCM0022  KB02 HCT 116 C130(1.62); C133(1.62)  LDD0080  [1]
 LDCM0023  KB03 HCT 116 C130(2.23); C133(2.23)  LDD0081  [1]
 LDCM0024  KB05 HCT 116 C130(1.91); C133(1.91)  LDD0082  [1]
 LDCM0021  THZ1 HCT 116 C130(1.20); C133(1.20)  LDD2173  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
E3 ubiquitin-protein ligase TRIM23 (TRIM23) Arf family P36406
Zinc finger protein RFP (TRIM27) TRIM/RBCC family P14373
Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Sperm protein associated with the nucleus on the X chromosome N2 (SPANXN2) SPAN-X family Q5MJ10
Other
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
CCR4-NOT transcription complex subunit 11 (CNOT11) CNOT11 family Q9UKZ1
Golgin subfamily A member 2 (GOLGA2) GOLGA2 family Q08379

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
2 Cyclopropenone, Cyclopropeniminium Ion, and Cyclopropenethione as Novel Electrophilic Warheads for Potential Target Discovery of Triple-Negative Breast Cancer. J Med Chem. 2023 Feb 23;66(4):2851-2864. doi: 10.1021/acs.jmedchem.2c01889. Epub 2023 Feb 10.
3 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
4 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
5 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
6 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
7 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
8 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402