Details of the Target

General Information of Target

Target ID LDTP10369
Target Name Protein lin-37 homolog (LIN37)
Gene Name LIN37
Gene ID 55957
Synonyms
Protein lin-37 homolog; Antolefinin
3D Structure
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2D Sequence (FASTA)
Download
3D Structure (PDB)
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Sequence
MSGCDAREGDCCSRRCGAQDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAP
SGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKA
AVMATLLFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHA
MNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENG
IV
Target Bioclass
Other
Uniprot ID
Q96GY3
Ensemble ID
ENST00000301159.14
HGNC ID
HGNC:33234

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 10 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C176(2.98)  LDD3343  [1]
AHL-Pu-1
 Probe Info  		C28(3.02)  LDD0168  [2]
4-Iodoacetamidophenylacetylene
 Probe Info  		C28(0.00); C56(0.00)  LDD0038  [3]
IA-alkyne
 Probe Info  		C56(0.00); C28(0.00)  LDD0036  [3]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [3]
JW-RF-010
 Probe Info  		N.A.  LDD0026  [4]
NAIA_4
 Probe Info  		C28(0.00); C176(0.00)  LDD2226  [5]
IPM
 Probe Info  		N.A.  LDD0005  [6]
Phosphinate-6
 Probe Info  		C56(0.00); C28(0.00)  LDD0018  [7]
NAIA_5
 Probe Info  		N.A.  LDD2223  [5]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA HEK-293T C28(3.02)  LDD0168  [2]
 LDCM0026  4SU-RNA+native RNA HEK-293T C28(4.06)  LDD0169  [2]
 LDCM0214  AC1 HEK-293T C176(1.36); C28(1.02)  LDD1507  [8]
 LDCM0215  AC10 HEK-293T C28(1.37); C56(1.01)  LDD1508  [8]
 LDCM0226  AC11 HEK-293T C176(1.01); C28(1.13)  LDD1509  [8]
 LDCM0230  AC113 HEK-293T C56(1.19)  LDD0828  [9]
 LDCM0231  AC114 HEK-293T C56(0.94)  LDD0829  [9]
 LDCM0232  AC115 HEK-293T C56(1.08)  LDD0830  [9]
 LDCM0233  AC116 HEK-293T C56(0.98)  LDD0831  [9]
 LDCM0234  AC117 HEK-293T C56(1.22)  LDD0832  [9]
 LDCM0235  AC118 HEK-293T C56(1.01)  LDD0833  [9]
 LDCM0236  AC119 HEK-293T C56(1.09)  LDD0834  [9]
 LDCM0237  AC12 HEK-293T C176(1.09); C28(1.03)  LDD1510  [8]
 LDCM0238  AC120 HEK-293T C56(1.15)  LDD0836  [9]
 LDCM0239  AC121 HEK-293T C56(1.09)  LDD0837  [9]
 LDCM0240  AC122 HEK-293T C56(1.20)  LDD0838  [9]
 LDCM0241  AC123 HEK-293T C56(1.21)  LDD0839  [9]
 LDCM0242  AC124 HEK-293T C56(1.14)  LDD0840  [9]
 LDCM0243  AC125 HEK-293T C56(1.11)  LDD0841  [9]
 LDCM0244  AC126 HEK-293T C56(1.29)  LDD0842  [9]
 LDCM0245  AC127 HEK-293T C56(1.51)  LDD0843  [9]
 LDCM0259  AC14 HEK-293T C28(1.09)  LDD1512  [8]
 LDCM0270  AC15 HEK-293T C28(0.96)  LDD1513  [8]
 LDCM0276  AC17 HEK-293T C176(1.11); C28(0.97)  LDD1515  [8]
 LDCM0277  AC18 HEK-293T C28(1.05); C56(1.07)  LDD1516  [8]
 LDCM0278  AC19 HEK-293T C176(0.98); C28(1.50)  LDD1517  [8]
 LDCM0279  AC2 HEK-293T C28(1.08); C56(1.08)  LDD1518  [8]
 LDCM0280  AC20 HEK-293T C176(0.94); C28(1.03)  LDD1519  [8]
 LDCM0281  AC21 HEK-293T C28(0.99)  LDD1520  [8]
 LDCM0282  AC22 HEK-293T C28(0.98)  LDD1521  [8]
 LDCM0283  AC23 HEK-293T C28(0.97)  LDD1522  [8]
 LDCM0284  AC24 HEK-293T C176(0.73); C28(0.94); C56(0.88)  LDD1523  [8]
 LDCM0285  AC25 HEK-293T C56(0.97)  LDD0883  [9]
 LDCM0286  AC26 HEK-293T C56(0.98)  LDD0884  [9]
 LDCM0287  AC27 HEK-293T C56(1.00)  LDD0885  [9]
 LDCM0288  AC28 HEK-293T C56(0.69)  LDD0886  [9]
 LDCM0289  AC29 HEK-293T C56(0.90)  LDD0887  [9]
 LDCM0290  AC3 HEK-293T C176(0.94); C28(1.22)  LDD1529  [8]
 LDCM0291  AC30 HEK-293T C56(1.02)  LDD0889  [9]
 LDCM0292  AC31 HEK-293T C56(0.94)  LDD0890  [9]
 LDCM0293  AC32 HEK-293T C56(1.08)  LDD0891  [9]
 LDCM0294  AC33 HEK-293T C56(1.01)  LDD0892  [9]
 LDCM0295  AC34 HEK-293T C56(0.90)  LDD0893  [9]
 LDCM0296  AC35 HEK-293T C56(0.88)  LDD0894  [9]
 LDCM0297  AC36 HEK-293T C56(0.87)  LDD0895  [9]
 LDCM0298  AC37 HEK-293T C56(1.00)  LDD0896  [9]
 LDCM0299  AC38 HEK-293T C56(0.87)  LDD0897  [9]
 LDCM0300  AC39 HEK-293T C56(0.97)  LDD0898  [9]
 LDCM0301  AC4 HEK-293T C176(1.08); C28(1.01)  LDD1540  [8]
 LDCM0302  AC40 HEK-293T C56(0.82)  LDD0900  [9]
 LDCM0303  AC41 HEK-293T C56(0.85)  LDD0901  [9]
 LDCM0304  AC42 HEK-293T C56(0.93)  LDD0902  [9]
 LDCM0305  AC43 HEK-293T C56(1.07)  LDD0903  [9]
 LDCM0306  AC44 HEK-293T C56(1.09)  LDD0904  [9]
 LDCM0307  AC45 HEK-293T C56(0.99)  LDD0905  [9]
 LDCM0308  AC46 HEK-293T C56(1.02)  LDD0906  [9]
 LDCM0309  AC47 HEK-293T C56(1.06)  LDD0907  [9]
 LDCM0310  AC48 HEK-293T C56(1.10)  LDD0908  [9]
 LDCM0311  AC49 HEK-293T C56(1.09)  LDD0909  [9]
 LDCM0312  AC5 HEK-293T C28(1.04)  LDD1551  [8]
 LDCM0313  AC50 HEK-293T C56(0.92)  LDD0911  [9]
 LDCM0314  AC51 HEK-293T C56(0.96)  LDD0912  [9]
 LDCM0315  AC52 HEK-293T C56(0.86)  LDD0913  [9]
 LDCM0316  AC53 HEK-293T C56(0.94)  LDD0914  [9]
 LDCM0317  AC54 HEK-293T C56(1.09)  LDD0915  [9]
 LDCM0318  AC55 HEK-293T C56(0.99)  LDD0916  [9]
 LDCM0319  AC56 HEK-293T C56(1.01)  LDD0917  [9]
 LDCM0320  AC57 HEK-293T C56(0.94)  LDD0918  [9]
 LDCM0321  AC58 HEK-293T C56(0.96)  LDD0919  [9]
 LDCM0322  AC59 HEK-293T C56(0.78)  LDD0920  [9]
 LDCM0323  AC6 HEK-293T C28(1.07)  LDD1562  [8]
 LDCM0324  AC60 HEK-293T C56(0.77)  LDD0922  [9]
 LDCM0325  AC61 HEK-293T C56(0.81)  LDD0923  [9]
 LDCM0326  AC62 HEK-293T C56(0.77)  LDD0924  [9]
 LDCM0327  AC63 HEK-293T C56(0.67)  LDD0925  [9]
 LDCM0328  AC64 HEK-293T C56(0.81)  LDD0926  [9]
 LDCM0329  AC65 HEK-293T C56(0.76)  LDD0927  [9]
 LDCM0330  AC66 HEK-293T C56(0.78)  LDD0928  [9]
 LDCM0331  AC67 HEK-293T C56(0.75)  LDD0929  [9]
 LDCM0334  AC7 HEK-293T C28(0.96)  LDD1568  [8]
 LDCM0345  AC8 HEK-293T C176(0.83); C28(0.98); C56(0.91)  LDD1569  [8]
 LDCM0349  AC83 HEK-293T C56(0.99)  LDD0947  [9]
 LDCM0350  AC84 HEK-293T C56(1.01)  LDD0948  [9]
 LDCM0351  AC85 HEK-293T C56(1.08)  LDD0949  [9]
 LDCM0352  AC86 HEK-293T C56(0.98)  LDD0950  [9]
 LDCM0353  AC87 HEK-293T C56(1.04)  LDD0951  [9]
 LDCM0354  AC88 HEK-293T C56(0.97)  LDD0952  [9]
 LDCM0355  AC89 HEK-293T C56(0.95)  LDD0953  [9]
 LDCM0357  AC90 HEK-293T C56(0.94)  LDD0955  [9]
 LDCM0358  AC91 HEK-293T C56(0.98)  LDD0956  [9]
 LDCM0359  AC92 HEK-293T C56(1.00)  LDD0957  [9]
 LDCM0360  AC93 HEK-293T C56(0.87)  LDD0958  [9]
 LDCM0361  AC94 HEK-293T C56(0.97)  LDD0959  [9]
 LDCM0362  AC95 HEK-293T C56(1.06)  LDD0960  [9]
 LDCM0363  AC96 HEK-293T C56(1.04)  LDD0961  [9]
 LDCM0364  AC97 HEK-293T C56(1.26)  LDD0962  [9]
 LDCM0248  AKOS034007472 HEK-293T C28(1.01)  LDD1511  [8]
 LDCM0356  AKOS034007680 HEK-293T C176(1.06); C28(0.95)  LDD1570  [8]
 LDCM0275  AKOS034007705 HEK-293T C176(1.09); C28(0.97); C56(0.93)  LDD1514  [8]
 LDCM0020  ARS-1620 HCC44 C56(1.05)  LDD2171  [9]
 LDCM0368  CL10 HEK-293T C28(0.85)  LDD1572  [8]
 LDCM0369  CL100 HEK-293T C176(1.02); C119(0.96)  LDD1573  [8]
 LDCM0371  CL102 HEK-293T C176(1.01); C28(0.96)  LDD1575  [8]
 LDCM0372  CL103 HEK-293T C176(1.14); C28(1.14)  LDD1576  [8]
 LDCM0373  CL104 HEK-293T C176(0.99); C119(0.92)  LDD1577  [8]
 LDCM0375  CL106 HEK-293T C176(1.07); C28(0.81)  LDD1579  [8]
 LDCM0376  CL107 HEK-293T C176(1.02); C28(1.07)  LDD1580  [8]
 LDCM0377  CL108 HEK-293T C176(1.06); C119(0.79)  LDD1581  [8]
 LDCM0379  CL11 HEK-293T C28(1.02)  LDD1583  [8]
 LDCM0380  CL110 HEK-293T C176(1.00); C28(2.28)  LDD1584  [8]
 LDCM0381  CL111 HEK-293T C176(1.08); C28(1.02)  LDD1585  [8]
 LDCM0382  CL112 HEK-293T C56(0.88)  LDD0980  [9]
 LDCM0383  CL113 HEK-293T C56(1.04)  LDD0981  [9]
 LDCM0384  CL114 HEK-293T C56(1.11)  LDD0982  [9]
 LDCM0385  CL115 HEK-293T C56(0.95)  LDD0983  [9]
 LDCM0386  CL116 HEK-293T C56(1.06)  LDD0984  [9]
 LDCM0387  CL117 HEK-293T C56(0.98)  LDD0985  [9]
 LDCM0388  CL118 HEK-293T C56(0.91)  LDD0986  [9]
 LDCM0389  CL119 HEK-293T C56(0.91)  LDD0987  [9]
 LDCM0390  CL12 HEK-293T C176(0.93); C28(0.71); C56(0.85)  LDD1594  [8]
 LDCM0391  CL120 HEK-293T C56(0.99)  LDD0989  [9]
 LDCM0392  CL121 HEK-293T C56(1.00)  LDD0990  [9]
 LDCM0393  CL122 HEK-293T C56(0.97)  LDD0991  [9]
 LDCM0394  CL123 HEK-293T C56(1.05)  LDD0992  [9]
 LDCM0395  CL124 HEK-293T C56(0.99)  LDD0993  [9]
 LDCM0396  CL125 HEK-293T C56(0.99)  LDD0994  [9]
 LDCM0397  CL126 HEK-293T C56(1.03)  LDD0995  [9]
 LDCM0398  CL127 HEK-293T C56(1.08)  LDD0996  [9]
 LDCM0399  CL128 HEK-293T C56(1.08)  LDD0997  [9]
 LDCM0401  CL14 HEK-293T C176(1.24); C28(0.77)  LDD1605  [8]
 LDCM0402  CL15 HEK-293T C176(1.02); C28(1.08)  LDD1606  [8]
 LDCM0403  CL16 HEK-293T C56(0.95)  LDD1001  [9]
 LDCM0404  CL17 HEK-293T C56(0.88)  LDD1002  [9]
 LDCM0405  CL18 HEK-293T C56(0.87)  LDD1003  [9]
 LDCM0406  CL19 HEK-293T C56(1.10)  LDD1004  [9]
 LDCM0407  CL2 HEK-293T C176(1.33); C28(0.86)  LDD1611  [8]
 LDCM0408  CL20 HEK-293T C56(0.75)  LDD1006  [9]
 LDCM0409  CL21 HEK-293T C56(0.75)  LDD1007  [9]
 LDCM0410  CL22 HEK-293T C56(0.83)  LDD1008  [9]
 LDCM0411  CL23 HEK-293T C56(0.82)  LDD1009  [9]
 LDCM0412  CL24 HEK-293T C56(0.70)  LDD1010  [9]
 LDCM0413  CL25 HEK-293T C56(1.02)  LDD1011  [9]
 LDCM0414  CL26 HEK-293T C56(0.76)  LDD1012  [9]
 LDCM0415  CL27 HEK-293T C56(1.10)  LDD1013  [9]
 LDCM0416  CL28 HEK-293T C56(0.94)  LDD1014  [9]
 LDCM0417  CL29 HEK-293T C56(0.73)  LDD1015  [9]
 LDCM0418  CL3 HEK-293T C176(1.24); C28(0.98)  LDD1622  [8]
 LDCM0419  CL30 HEK-293T C56(1.04)  LDD1017  [9]
 LDCM0420  CL31 HEK-293T C56(0.72)  LDD1018  [9]
 LDCM0421  CL32 HEK-293T C56(0.83)  LDD1019  [9]
 LDCM0422  CL33 HEK-293T C56(0.84)  LDD1020  [9]
 LDCM0423  CL34 HEK-293T C56(0.97)  LDD1021  [9]
 LDCM0424  CL35 HEK-293T C56(0.82)  LDD1022  [9]
 LDCM0425  CL36 HEK-293T C56(0.93)  LDD1023  [9]
 LDCM0426  CL37 HEK-293T C56(0.84)  LDD1024  [9]
 LDCM0428  CL39 HEK-293T C56(0.91)  LDD1026  [9]
 LDCM0429  CL4 HEK-293T C176(1.02); C119(0.91)  LDD1633  [8]
 LDCM0430  CL40 HEK-293T C56(0.76)  LDD1028  [9]
 LDCM0431  CL41 HEK-293T C56(0.79)  LDD1029  [9]
 LDCM0432  CL42 HEK-293T C56(0.98)  LDD1030  [9]
 LDCM0433  CL43 HEK-293T C56(0.91)  LDD1031  [9]
 LDCM0434  CL44 HEK-293T C56(0.84)  LDD1032  [9]
 LDCM0435  CL45 HEK-293T C56(0.85)  LDD1033  [9]
 LDCM0436  CL46 HEK-293T C56(0.72)  LDD1034  [9]
 LDCM0437  CL47 HEK-293T C56(0.84)  LDD1035  [9]
 LDCM0438  CL48 HEK-293T C56(0.81)  LDD1036  [9]
 LDCM0439  CL49 HEK-293T C56(0.93)  LDD1037  [9]
 LDCM0440  CL5 HEK-293T C176(1.33); C28(0.97)  LDD1644  [8]
 LDCM0441  CL50 HEK-293T C56(1.07)  LDD1039  [9]
 LDCM0442  CL51 HEK-293T C56(0.96)  LDD1040  [9]
 LDCM0443  CL52 HEK-293T C56(0.99)  LDD1041  [9]
 LDCM0444  CL53 HEK-293T C56(1.10)  LDD1042  [9]
 LDCM0445  CL54 HEK-293T C56(0.93)  LDD1043  [9]
 LDCM0446  CL55 HEK-293T C56(0.93)  LDD1044  [9]
 LDCM0447  CL56 HEK-293T C56(0.98)  LDD1045  [9]
 LDCM0448  CL57 HEK-293T C56(1.12)  LDD1046  [9]
 LDCM0449  CL58 HEK-293T C56(1.06)  LDD1047  [9]
 LDCM0450  CL59 HEK-293T C56(0.93)  LDD1048  [9]
 LDCM0451  CL6 HEK-293T C28(0.97); C56(1.05)  LDD1654  [8]
 LDCM0452  CL60 HEK-293T C56(1.02)  LDD1050  [9]
 LDCM0454  CL62 HEK-293T C176(1.10); C28(1.11)  LDD1657  [8]
 LDCM0455  CL63 HEK-293T C176(1.10); C28(1.02)  LDD1658  [8]
 LDCM0456  CL64 HEK-293T C176(0.96); C119(0.95)  LDD1659  [8]
 LDCM0457  CL65 HEK-293T C176(1.19); C28(1.02)  LDD1660  [8]
 LDCM0458  CL66 HEK-293T C28(1.18); C56(1.19)  LDD1661  [8]
 LDCM0459  CL67 HEK-293T C176(0.99); C28(0.95)  LDD1662  [8]
 LDCM0460  CL68 HEK-293T C176(1.14); C28(0.91)  LDD1663  [8]
 LDCM0461  CL69 HEK-293T C28(1.01)  LDD1664  [8]
 LDCM0462  CL7 HEK-293T C176(1.06); C28(0.99)  LDD1665  [8]
 LDCM0463  CL70 HEK-293T C28(0.93)  LDD1666  [8]
 LDCM0464  CL71 HEK-293T C28(0.97)  LDD1667  [8]
 LDCM0465  CL72 HEK-293T C176(1.36); C28(0.81); C56(0.90)  LDD1668  [8]
 LDCM0467  CL74 HEK-293T C176(1.12); C28(0.91)  LDD1670  [8]
 LDCM0469  CL76 HEK-293T C176(1.02); C119(0.89)  LDD1672  [8]
 LDCM0470  CL77 HEK-293T C176(1.12); C28(1.05)  LDD1673  [8]
 LDCM0471  CL78 HEK-293T C28(1.26); C56(1.08)  LDD1674  [8]
 LDCM0472  CL79 HEK-293T C176(0.99); C28(1.02)  LDD1675  [8]
 LDCM0473  CL8 HEK-293T C176(1.15); C28(0.87)  LDD1676  [8]
 LDCM0474  CL80 HEK-293T C176(1.03); C28(0.88)  LDD1677  [8]
 LDCM0475  CL81 HEK-293T C28(1.00)  LDD1678  [8]
 LDCM0476  CL82 HEK-293T C28(0.94)  LDD1679  [8]
 LDCM0477  CL83 HEK-293T C28(1.02)  LDD1680  [8]
 LDCM0478  CL84 HEK-293T C176(1.30); C28(0.93); C56(0.83)  LDD1681  [8]
 LDCM0480  CL86 HEK-293T C176(1.05); C28(0.66)  LDD1683  [8]
 LDCM0481  CL87 HEK-293T C176(1.06); C28(1.03)  LDD1684  [8]
 LDCM0482  CL88 HEK-293T C176(0.92); C119(0.97)  LDD1685  [8]
 LDCM0483  CL89 HEK-293T C176(1.29); C28(0.92)  LDD1686  [8]
 LDCM0484  CL9 HEK-293T C28(0.98)  LDD1687  [8]
 LDCM0485  CL90 HEK-293T C28(1.06); C56(1.05)  LDD1688  [8]
 LDCM0486  CL91 HEK-293T C176(0.81); C28(1.02)  LDD1689  [8]
 LDCM0487  CL92 HEK-293T C176(1.11); C28(0.86)  LDD1690  [8]
 LDCM0488  CL93 HEK-293T C28(0.89)  LDD1691  [8]
 LDCM0489  CL94 HEK-293T C28(1.02)  LDD1692  [8]
 LDCM0490  CL95 HEK-293T C28(0.86)  LDD1693  [8]
 LDCM0491  CL96 HEK-293T C176(0.93); C28(0.92); C56(0.86)  LDD1694  [8]
 LDCM0493  CL98 HEK-293T C176(1.04); C28(0.86)  LDD1696  [8]
 LDCM0494  CL99 HEK-293T C176(1.03); C28(1.02)  LDD1697  [8]
 LDCM0495  E2913 HEK-293T C176(1.09); C28(1.02)  LDD1698  [8]
 LDCM0468  Fragment33 HEK-293T C176(1.02); C28(0.98)  LDD1671  [8]
 LDCM0427  Fragment51 HEK-293T C56(0.85)  LDD1025  [9]
 LDCM0022  KB02 HEK-293T C56(0.97); C176(0.98); C119(1.17); C28(0.97)  LDD1492  [8]
 LDCM0023  KB03 HEK-293T C56(1.06); C176(1.07); C119(1.04); C28(0.99)  LDD1497  [8]
 LDCM0024  KB05 NCI-H1299 C176(2.98)  LDD3343  [1]
 LDCM0021  THZ1 HCT 116 C56(1.05)  LDD2173  [9]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Kinesin-like protein KIFC3 (KIFC3) Kinesin family Q9BVG8
Tripartite motif-containing protein 54 (TRIM54) . Q9BYV2
Transcription factor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Zinc finger protein 76 (ZNF76) Krueppel C2H2-type zinc-finger protein family P36508
Other
Click To Hide/Show 12 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cyclin-D1-binding protein 1 (CCNDBP1) CCNDBP1 family O95273
Cerebellar degeneration-related protein 2 (CDR2) CDR2 family Q01850
Keratin, type I cuticular Ha1 (KRT31) Intermediate filament family Q15323
Keratin, type I cytoskeletal 40 (KRT40) Intermediate filament family Q6A162
Leucine zipper putative tumor suppressor 2 (LZTS2) LZTS2 family Q9BRK4
Paraneoplastic antigen Ma1 (PNMA1) PNMA family Q8ND90
Testis-expressed protein 11 (TEX11) SPO22 family Q8IYF3
Tuftelin-interacting protein 11 (TFIP11) TFP11/STIP family Q9UBB9
Centrosomal protein of 70 kDa (CEP70) . Q8NHQ1
Melanoma-associated antigen 6 (MAGEA6) . P43360
Proline-serine-threonine phosphatase-interacting protein 1 (PSTPIP1) . O43586
TNF receptor-associated factor 1 (TRAF1) . Q13077

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
2 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
3 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
4 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
5 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
6 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
7 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
8 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
9 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.