Details of the Target

General Information of Target

Target ID LDTP00816
Target Name Protein sprouty homolog 1 (SPRY1)
Gene Name SPRY1
Gene ID 10252
Synonyms
Protein sprouty homolog 1; Spry-1
3D Structure
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2D Sequence (FASTA)
Download
3D Structure (PDB)
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Sequence
MDPQNQHGSGSSLVVIQQPSLDSRQRLDYEREIQPTAILSLDQIKAIRGSNEYTEGPSVV
KRPAPRTAPRQEKHERTHEIIPINVNNNYEHRHTSHLGHAVLPSNARGPILSRSTSTGSA
ASSGSNSSASSEQGLLGRSPPTRPVPGHRSERAIRTQPKQLIVDDLKGSLKEDLTQHKFI
CEQCGKCKCGECTAPRTLPSCLACNRQCLCSAESMVEYGTCMCLVKGIFYHCSNDDEGDS
YSDNPCSCSQSHCCSRYLCMGAMSLFLPCLLCYPPAKGCLKLCRRCYDWIHRPGCRCKNS
NTVYCKLESCPSRGQGKPS
Target Type
Literature-reported
Target Bioclass
Other
Family
Sprouty family
Subcellular location
Cytoplasm
Function
Inhibits fibroblast growth factor (FGF)-induced retinal lens fiber differentiation, probably by inhibiting FGF-mediated phosphorylation of ERK1/2. Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells.
TTD ID
T76540
Uniprot ID
O43609
DrugMap ID
TT0PSN6
Ensemble ID
ENST00000339241.1
HGNC ID
HGNC:11269

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
AHL-Pu-1
 Probe Info  		C310(2.82)  LDD0171  [1]
DBIA
 Probe Info  		C305(2.28); C181(1.16); C184(1.16)  LDD0080  [2]
W1
 Probe Info  		N.A.  LDD0236  [3]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0026  4SU-RNA+native RNA DM93 C310(2.82)  LDD0171  [1]
 LDCM0214  AC1 HEK-293T C305(1.18); C184(0.96)  LDD1507  [4]
 LDCM0215  AC10 HEK-293T C305(1.13); C184(0.99)  LDD1508  [4]
 LDCM0226  AC11 HEK-293T C305(1.02); C184(0.88)  LDD1509  [4]
 LDCM0237  AC12 HEK-293T C305(1.06); C181(1.00); C184(1.01)  LDD1510  [4]
 LDCM0259  AC14 HEK-293T C305(1.04); C184(1.12)  LDD1512  [4]
 LDCM0270  AC15 HEK-293T C305(1.07); C184(1.05)  LDD1513  [4]
 LDCM0276  AC17 HEK-293T C305(1.14); C184(0.95)  LDD1515  [4]
 LDCM0277  AC18 HEK-293T C305(1.04); C184(0.97)  LDD1516  [4]
 LDCM0278  AC19 HEK-293T C305(2.15); C184(0.68)  LDD1517  [4]
 LDCM0279  AC2 HEK-293T C305(1.07); C184(0.92)  LDD1518  [4]
 LDCM0280  AC20 HEK-293T C305(1.03); C181(1.04); C184(1.00)  LDD1519  [4]
 LDCM0281  AC21 HEK-293T C305(1.03); C184(0.99)  LDD1520  [4]
 LDCM0282  AC22 HEK-293T C305(0.98); C184(0.98)  LDD1521  [4]
 LDCM0283  AC23 HEK-293T C305(1.10); C184(1.04)  LDD1522  [4]
 LDCM0284  AC24 HEK-293T C305(1.03); C184(1.00)  LDD1523  [4]
 LDCM0285  AC25 HEK-293T C305(1.12); C184(1.03)  LDD1524  [4]
 LDCM0286  AC26 HEK-293T C305(1.05); C184(0.96)  LDD1525  [4]
 LDCM0287  AC27 HEK-293T C305(1.05); C184(0.90)  LDD1526  [4]
 LDCM0288  AC28 HEK-293T C305(1.04); C181(1.01); C184(1.03)  LDD1527  [4]
 LDCM0289  AC29 HEK-293T C305(1.03); C184(0.83)  LDD1528  [4]
 LDCM0290  AC3 HEK-293T C305(1.06); C184(0.97)  LDD1529  [4]
 LDCM0291  AC30 HEK-293T C305(1.03); C184(1.12)  LDD1530  [4]
 LDCM0292  AC31 HEK-293T C305(1.02); C184(1.12)  LDD1531  [4]
 LDCM0293  AC32 HEK-293T C305(1.02); C184(1.16)  LDD1532  [4]
 LDCM0294  AC33 HEK-293T C305(1.06); C184(1.01)  LDD1533  [4]
 LDCM0295  AC34 HEK-293T C305(1.16); C184(0.98)  LDD1534  [4]
 LDCM0296  AC35 HEK-293T C305(1.10); C184(0.96)  LDD1535  [4]
 LDCM0297  AC36 HEK-293T C305(1.06); C181(0.99); C184(0.88)  LDD1536  [4]
 LDCM0298  AC37 HEK-293T C305(1.02); C184(0.91)  LDD1537  [4]
 LDCM0299  AC38 HEK-293T C305(1.03); C184(0.96)  LDD1538  [4]
 LDCM0300  AC39 HEK-293T C305(1.10); C184(1.01)  LDD1539  [4]
 LDCM0301  AC4 HEK-293T C305(1.14); C181(0.97); C184(1.09)  LDD1540  [4]
 LDCM0302  AC40 HEK-293T C305(1.11); C184(0.91)  LDD1541  [4]
 LDCM0303  AC41 HEK-293T C305(1.08); C184(0.88)  LDD1542  [4]
 LDCM0304  AC42 HEK-293T C305(1.11); C184(1.00)  LDD1543  [4]
 LDCM0305  AC43 HEK-293T C305(1.03); C184(0.96)  LDD1544  [4]
 LDCM0306  AC44 HEK-293T C305(1.11); C181(1.09); C184(1.03)  LDD1545  [4]
 LDCM0307  AC45 HEK-293T C305(1.04); C184(0.93)  LDD1546  [4]
 LDCM0308  AC46 HEK-293T C305(1.09); C184(1.09)  LDD1547  [4]
 LDCM0309  AC47 HEK-293T C305(1.16); C184(0.99)  LDD1548  [4]
 LDCM0310  AC48 HEK-293T C305(1.04); C184(0.86)  LDD1549  [4]
 LDCM0311  AC49 HEK-293T C305(1.10); C184(0.99)  LDD1550  [4]
 LDCM0312  AC5 HEK-293T C305(1.03); C184(0.93)  LDD1551  [4]
 LDCM0313  AC50 HEK-293T C305(1.16); C184(0.98)  LDD1552  [4]
 LDCM0314  AC51 HEK-293T C305(1.05); C184(1.03)  LDD1553  [4]
 LDCM0315  AC52 HEK-293T C305(1.06); C181(0.98); C184(1.15)  LDD1554  [4]
 LDCM0316  AC53 HEK-293T C305(1.03); C184(0.94)  LDD1555  [4]
 LDCM0317  AC54 HEK-293T C305(1.07); C184(1.05)  LDD1556  [4]
 LDCM0318  AC55 HEK-293T C305(1.07); C184(1.04)  LDD1557  [4]
 LDCM0319  AC56 HEK-293T C305(1.12); C184(0.91)  LDD1558  [4]
 LDCM0320  AC57 HEK-293T C305(1.09); C184(1.06)  LDD1559  [4]
 LDCM0321  AC58 HEK-293T C305(1.14); C184(0.90)  LDD1560  [4]
 LDCM0322  AC59 HEK-293T C305(1.00); C184(1.05)  LDD1561  [4]
 LDCM0323  AC6 HEK-293T C305(1.09); C184(1.04)  LDD1562  [4]
 LDCM0324  AC60 HEK-293T C305(1.00); C181(0.96); C184(1.03)  LDD1563  [4]
 LDCM0325  AC61 HEK-293T C305(1.01); C184(1.08)  LDD1564  [4]
 LDCM0326  AC62 HEK-293T C305(1.04); C184(0.98)  LDD1565  [4]
 LDCM0327  AC63 HEK-293T C305(1.07); C184(1.04)  LDD1566  [4]
 LDCM0328  AC64 HEK-293T C305(1.11); C184(0.97)  LDD1567  [4]
 LDCM0334  AC7 HEK-293T C305(1.04); C184(1.02)  LDD1568  [4]
 LDCM0345  AC8 HEK-293T C305(1.09); C184(0.96)  LDD1569  [4]
 LDCM0248  AKOS034007472 HEK-293T C305(1.03); C184(0.77)  LDD1511  [4]
 LDCM0356  AKOS034007680 HEK-293T C305(1.03); C184(0.91)  LDD1570  [4]
 LDCM0275  AKOS034007705 HEK-293T C305(1.06); C184(1.00)  LDD1514  [4]
 LDCM0367  CL1 HEK-293T C184(0.98)  LDD1571  [4]
 LDCM0368  CL10 HEK-293T C305(1.06); C184(1.13)  LDD1572  [4]
 LDCM0369  CL100 HEK-293T C305(1.13); C184(1.00)  LDD1573  [4]
 LDCM0370  CL101 HEK-293T C184(1.09)  LDD1574  [4]
 LDCM0371  CL102 HEK-293T C305(1.00); C184(1.00)  LDD1575  [4]
 LDCM0372  CL103 HEK-293T C305(1.10); C184(0.90)  LDD1576  [4]
 LDCM0373  CL104 HEK-293T C305(1.08); C184(0.95)  LDD1577  [4]
 LDCM0374  CL105 HEK-293T C184(0.87)  LDD1578  [4]
 LDCM0375  CL106 HEK-293T C305(1.02); C184(0.90)  LDD1579  [4]
 LDCM0376  CL107 HEK-293T C305(1.11); C184(0.95)  LDD1580  [4]
 LDCM0377  CL108 HEK-293T C305(1.01); C184(0.98)  LDD1581  [4]
 LDCM0378  CL109 HEK-293T C184(0.98)  LDD1582  [4]
 LDCM0379  CL11 HEK-293T C305(1.08); C184(1.03)  LDD1583  [4]
 LDCM0380  CL110 HEK-293T C305(0.98); C184(0.98)  LDD1584  [4]
 LDCM0381  CL111 HEK-293T C305(1.12); C184(0.97)  LDD1585  [4]
 LDCM0382  CL112 HEK-293T C305(1.05); C184(0.84)  LDD1586  [4]
 LDCM0383  CL113 HEK-293T C184(1.00)  LDD1587  [4]
 LDCM0384  CL114 HEK-293T C305(1.02); C184(0.95)  LDD1588  [4]
 LDCM0385  CL115 HEK-293T C305(1.12); C184(0.94)  LDD1589  [4]
 LDCM0386  CL116 HEK-293T C305(1.07); C184(1.04)  LDD1590  [4]
 LDCM0387  CL117 HEK-293T C184(1.11)  LDD1591  [4]
 LDCM0388  CL118 HEK-293T C305(1.15); C184(0.89)  LDD1592  [4]
 LDCM0389  CL119 HEK-293T C305(1.18); C184(0.92)  LDD1593  [4]
 LDCM0390  CL12 HEK-293T C305(1.08); C184(0.92)  LDD1594  [4]
 LDCM0391  CL120 HEK-293T C305(1.12); C184(1.07)  LDD1595  [4]
 LDCM0392  CL121 HEK-293T C184(1.03)  LDD1596  [4]
 LDCM0393  CL122 HEK-293T C305(1.06); C184(1.13)  LDD1597  [4]
 LDCM0394  CL123 HEK-293T C305(1.08); C184(0.82)  LDD1598  [4]
 LDCM0395  CL124 HEK-293T C305(1.15); C184(0.96)  LDD1599  [4]
 LDCM0396  CL125 HEK-293T C184(0.95)  LDD1600  [4]
 LDCM0397  CL126 HEK-293T C305(1.03); C184(0.99)  LDD1601  [4]
 LDCM0398  CL127 HEK-293T C305(1.03); C184(0.87)  LDD1602  [4]
 LDCM0399  CL128 HEK-293T C305(1.08); C184(0.94)  LDD1603  [4]
 LDCM0400  CL13 HEK-293T C184(1.05)  LDD1604  [4]
 LDCM0401  CL14 HEK-293T C305(1.03); C184(1.03)  LDD1605  [4]
 LDCM0402  CL15 HEK-293T C305(1.21); C184(0.85)  LDD1606  [4]
 LDCM0403  CL16 HEK-293T C305(1.06); C184(1.15)  LDD1607  [4]
 LDCM0404  CL17 HEK-293T C305(0.94); C184(0.78)  LDD1608  [4]
 LDCM0405  CL18 HEK-293T C305(1.07); C184(1.05)  LDD1609  [4]
 LDCM0406  CL19 HEK-293T C305(1.03); C184(1.16)  LDD1610  [4]
 LDCM0407  CL2 HEK-293T C305(1.02); C184(1.04)  LDD1611  [4]
 LDCM0408  CL20 HEK-293T C305(1.06); C181(1.11); C184(0.94)  LDD1612  [4]
 LDCM0409  CL21 HEK-293T C305(1.09); C184(1.00)  LDD1613  [4]
 LDCM0410  CL22 HEK-293T C305(1.14); C184(1.28)  LDD1614  [4]
 LDCM0411  CL23 HEK-293T C305(1.13); C184(1.07)  LDD1615  [4]
 LDCM0412  CL24 HEK-293T C305(1.07); C184(0.78)  LDD1616  [4]
 LDCM0413  CL25 HEK-293T C184(0.97)  LDD1617  [4]
 LDCM0414  CL26 HEK-293T C305(0.95); C184(0.96)  LDD1618  [4]
 LDCM0415  CL27 HEK-293T C305(1.11); C184(0.89)  LDD1619  [4]
 LDCM0416  CL28 HEK-293T C305(0.99); C184(0.99)  LDD1620  [4]
 LDCM0417  CL29 HEK-293T C305(1.15); C184(0.86)  LDD1621  [4]
 LDCM0418  CL3 HEK-293T C305(1.06); C184(1.02)  LDD1622  [4]
 LDCM0419  CL30 HEK-293T C305(1.03); C184(0.98)  LDD1623  [4]
 LDCM0420  CL31 HEK-293T C305(1.07); C184(1.00)  LDD1624  [4]
 LDCM0421  CL32 HEK-293T C305(1.01); C181(0.98); C184(0.98)  LDD1625  [4]
 LDCM0422  CL33 HEK-293T C305(1.04); C184(0.93)  LDD1626  [4]
 LDCM0423  CL34 HEK-293T C305(0.95); C184(1.05)  LDD1627  [4]
 LDCM0424  CL35 HEK-293T C305(0.96); C184(1.08)  LDD1628  [4]
 LDCM0425  CL36 HEK-293T C305(0.90); C184(0.93)  LDD1629  [4]
 LDCM0426  CL37 HEK-293T C184(0.97)  LDD1630  [4]
 LDCM0428  CL39 HEK-293T C305(0.98); C184(0.94)  LDD1632  [4]
 LDCM0429  CL4 HEK-293T C305(1.02); C184(1.02)  LDD1633  [4]
 LDCM0430  CL40 HEK-293T C305(0.99); C184(0.95)  LDD1634  [4]
 LDCM0431  CL41 HEK-293T C305(1.03); C184(0.93)  LDD1635  [4]
 LDCM0432  CL42 HEK-293T C305(1.00); C184(0.92)  LDD1636  [4]
 LDCM0433  CL43 HEK-293T C305(0.99); C184(0.90)  LDD1637  [4]
 LDCM0434  CL44 HEK-293T C305(1.09); C181(0.94); C184(0.89)  LDD1638  [4]
 LDCM0435  CL45 HEK-293T C305(1.04); C184(0.83)  LDD1639  [4]
 LDCM0436  CL46 HEK-293T C305(1.04); C184(1.15)  LDD1640  [4]
 LDCM0437  CL47 HEK-293T C305(0.94); C184(1.03)  LDD1641  [4]
 LDCM0438  CL48 HEK-293T C305(1.01); C184(1.18)  LDD1642  [4]
 LDCM0439  CL49 HEK-293T C184(0.95)  LDD1643  [4]
 LDCM0440  CL5 HEK-293T C305(1.02); C184(0.91)  LDD1644  [4]
 LDCM0441  CL50 HEK-293T C305(0.94); C184(1.02)  LDD1645  [4]
 LDCM0443  CL52 HEK-293T C305(1.07); C184(0.89)  LDD1646  [4]
 LDCM0444  CL53 HEK-293T C305(1.06); C184(0.89)  LDD1647  [4]
 LDCM0445  CL54 HEK-293T C305(1.08); C184(0.94)  LDD1648  [4]
 LDCM0446  CL55 HEK-293T C305(1.03); C184(0.99)  LDD1649  [4]
 LDCM0447  CL56 HEK-293T C305(0.94); C181(0.94); C184(1.01)  LDD1650  [4]
 LDCM0448  CL57 HEK-293T C305(1.11); C184(0.88)  LDD1651  [4]
 LDCM0449  CL58 HEK-293T C305(0.97); C184(1.14)  LDD1652  [4]
 LDCM0450  CL59 HEK-293T C305(1.09); C184(0.99)  LDD1653  [4]
 LDCM0451  CL6 HEK-293T C305(1.12); C184(1.04)  LDD1654  [4]
 LDCM0452  CL60 HEK-293T C305(1.10); C184(0.86)  LDD1655  [4]
 LDCM0453  CL61 HEK-293T C184(1.33)  LDD1656  [4]
 LDCM0454  CL62 HEK-293T C305(0.99); C184(0.93)  LDD1657  [4]
 LDCM0455  CL63 HEK-293T C305(1.17); C184(0.90)  LDD1658  [4]
 LDCM0456  CL64 HEK-293T C305(1.01); C184(1.00)  LDD1659  [4]
 LDCM0457  CL65 HEK-293T C305(1.06); C184(0.92)  LDD1660  [4]
 LDCM0458  CL66 HEK-293T C305(1.09); C184(1.04)  LDD1661  [4]
 LDCM0459  CL67 HEK-293T C305(1.00); C184(1.01)  LDD1662  [4]
 LDCM0460  CL68 HEK-293T C305(1.03); C181(1.03); C184(1.04)  LDD1663  [4]
 LDCM0461  CL69 HEK-293T C305(1.05); C184(0.89)  LDD1664  [4]
 LDCM0462  CL7 HEK-293T C305(1.00); C184(1.07)  LDD1665  [4]
 LDCM0463  CL70 HEK-293T C305(1.07); C184(1.12)  LDD1666  [4]
 LDCM0464  CL71 HEK-293T C305(1.13); C184(1.06)  LDD1667  [4]
 LDCM0465  CL72 HEK-293T C305(0.92); C184(0.89)  LDD1668  [4]
 LDCM0466  CL73 HEK-293T C184(0.91)  LDD1669  [4]
 LDCM0467  CL74 HEK-293T C305(1.02); C184(1.03)  LDD1670  [4]
 LDCM0469  CL76 HEK-293T C305(1.00); C184(0.95)  LDD1672  [4]
 LDCM0470  CL77 HEK-293T C305(1.04); C184(0.94)  LDD1673  [4]
 LDCM0471  CL78 HEK-293T C305(1.08); C184(1.00)  LDD1674  [4]
 LDCM0472  CL79 HEK-293T C305(1.06); C184(0.95)  LDD1675  [4]
 LDCM0473  CL8 HEK-293T C305(1.17); C181(0.78); C184(0.82)  LDD1676  [4]
 LDCM0474  CL80 HEK-293T C305(1.07); C181(1.00); C184(1.17)  LDD1677  [4]
 LDCM0475  CL81 HEK-293T C305(1.04); C184(0.82)  LDD1678  [4]
 LDCM0476  CL82 HEK-293T C305(1.03); C184(1.10)  LDD1679  [4]
 LDCM0477  CL83 HEK-293T C305(1.11); C184(0.99)  LDD1680  [4]
 LDCM0478  CL84 HEK-293T C305(0.93); C184(0.78)  LDD1681  [4]
 LDCM0479  CL85 HEK-293T C184(0.92)  LDD1682  [4]
 LDCM0480  CL86 HEK-293T C305(0.99); C184(0.92)  LDD1683  [4]
 LDCM0481  CL87 HEK-293T C305(1.06); C184(0.87)  LDD1684  [4]
 LDCM0482  CL88 HEK-293T C305(1.03); C184(0.89)  LDD1685  [4]
 LDCM0483  CL89 HEK-293T C305(1.02); C184(0.85)  LDD1686  [4]
 LDCM0484  CL9 HEK-293T C305(1.01); C184(0.87)  LDD1687  [4]
 LDCM0485  CL90 HEK-293T C305(1.09); C184(0.86)  LDD1688  [4]
 LDCM0486  CL91 HEK-293T C305(0.99); C184(1.09)  LDD1689  [4]
 LDCM0487  CL92 HEK-293T C305(0.99); C181(1.00); C184(0.98)  LDD1690  [4]
 LDCM0488  CL93 HEK-293T C305(1.01); C184(0.98)  LDD1691  [4]
 LDCM0489  CL94 HEK-293T C305(1.05); C184(1.07)  LDD1692  [4]
 LDCM0490  CL95 HEK-293T C305(0.98); C184(1.04)  LDD1693  [4]
 LDCM0491  CL96 HEK-293T C305(0.93); C184(0.91)  LDD1694  [4]
 LDCM0492  CL97 HEK-293T C184(1.06)  LDD1695  [4]
 LDCM0493  CL98 HEK-293T C305(1.02); C184(0.93)  LDD1696  [4]
 LDCM0494  CL99 HEK-293T C305(1.10); C184(0.94)  LDD1697  [4]
 LDCM0495  E2913 HEK-293T C305(1.16); C184(0.88)  LDD1698  [4]
 LDCM0468  Fragment33 HEK-293T C305(1.12); C184(0.90)  LDD1671  [4]
 LDCM0427  Fragment51 HEK-293T C305(1.02); C184(1.03)  LDD1631  [4]
 LDCM0022  KB02 HCT 116 C305(2.28); C181(1.16); C184(1.16)  LDD0080  [2]
 LDCM0023  KB03 HCT 116 C305(2.84); C181(1.43); C184(1.43)  LDD0081  [2]
 LDCM0024  KB05 HCT 116 C305(3.79); C181(0.80); C184(0.80)  LDD0082  [2]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 6 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
5'-AMP-activated protein kinase subunit beta-2 (PRKAB2) 5'-AMP-activated protein kinase beta subunit family O43741
DNA-directed RNA polymerases I and III subunit RPAC1 (POLR1C) Archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family O15160
Phenylalanine--tRNA ligase, mitochondrial (FARS2) Class-II aminoacyl-tRNA synthetase family O95363
Nucleotidyltransferase MB21D2 (MB21D2) Mab-21 family Q8IYB1
5'-AMP-activated protein kinase catalytic subunit alpha-2 (PRKAA2) CAMK Ser/Thr protein kinase family P54646
Protein-glutamine gamma-glutamyltransferase Z (TGM7) Transglutaminase family Q96PF1
Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
MyoD family inhibitor (MDFI) MDFI family Q99750
Transcription factor
Click To Hide/Show 8 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Homeobox protein Hox-A1 (HOXA1) Antp homeobox family P49639
Transcription factor AP-2-delta (TFAP2D) AP-2 family Q7Z6R9
Zinc finger protein 23 (ZNF23) Krueppel C2H2-type zinc-finger protein family P17027
Zinc finger protein 417 (ZNF417) Krueppel C2H2-type zinc-finger protein family Q8TAU3
Zinc finger protein 441 (ZNF441) Krueppel C2H2-type zinc-finger protein family Q8N8Z8
Zinc finger protein 837 (ZNF837) Krueppel C2H2-type zinc-finger protein family Q96EG3
Homeobox protein OTX1 (OTX1) Paired homeobox family P32242
Homeobox protein MOX-2 (MEOX2) . P50222
Other
Click To Hide/Show 45 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cerebellar degeneration-related protein 2-like (CDR2L) CDR2 family Q86X02
Chordin (CHRD) Chordin family Q9H2X0
Cysteine-rich tail protein 1 (CYSRT1) CYSRT1 family A8MQ03
Protein HEXIM2 (HEXIM2) HEXIM family Q96MH2
Protein INCA1 (INCA1) INCA family Q0VD86
Keratin, type I cuticular Ha1 (KRT31) Intermediate filament family Q15323
Keratin-associated protein 1-1 (KRTAP1-1) KRTAP type 1 family Q07627
Keratin-associated protein 1-3 (KRTAP1-3) KRTAP type 1 family Q8IUG1
Keratin-associated protein 10-11 (KRTAP10-11) KRTAP type 10 family P60412
Keratin-associated protein 10-5 (KRTAP10-5) KRTAP type 10 family P60370
Keratin-associated protein 10-7 (KRTAP10-7) KRTAP type 10 family P60409
Keratin-associated protein 10-8 (KRTAP10-8) KRTAP type 10 family P60410
Keratin-associated protein 10-9 (KRTAP10-9) KRTAP type 10 family P60411
Keratin-associated protein 12-2 (KRTAP12-2) KRTAP type 12 family P59991
Keratin-associated protein 12-3 (KRTAP12-3) KRTAP type 12 family P60328
Keratin-associated protein 3-2 (KRTAP3-2) KRTAP type 3 family Q9BYR7
Keratin-associated protein 4-12 (KRTAP4-12) KRTAP type 4 family Q9BQ66
Keratin-associated protein 4-2 (KRTAP4-2) KRTAP type 4 family Q9BYR5
Keratin-associated protein 5-9 (KRTAP5-9) KRTAP type 5 family P26371
Keratin-associated protein 9-2 (KRTAP9-2) KRTAP type 9 family Q9BYQ4
Keratin-associated protein 9-3 (KRTAP9-3) KRTAP type 9 family Q9BYQ3
Late cornified envelope protein 1A (LCE1A) LCE family Q5T7P2
Late cornified envelope protein 1B (LCE1B) LCE family Q5T7P3
Late cornified envelope protein 1C (LCE1C) LCE family Q5T751
Late cornified envelope protein 1D (LCE1D) LCE family Q5T752
Late cornified envelope protein 1F (LCE1F) LCE family Q5T754
Late cornified envelope protein 2A (LCE2A) LCE family Q5TA79
Late cornified envelope protein 2C (LCE2C) LCE family Q5TA81
Late cornified envelope protein 2D (LCE2D) LCE family Q5TA82
Late cornified envelope protein 3A (LCE3A) LCE family Q5TA76
Late cornified envelope protein 3C (LCE3C) LCE family Q5T5A8
Late cornified envelope protein 3D (LCE3D) LCE family Q9BYE3
Late cornified envelope protein 4A (LCE4A) LCE family Q5TA78
Late cornified envelope protein 5A (LCE5A) LCE family Q5TCM9
Zinc finger protein 330 (ZNF330) NOA36 family Q9Y3S2
Notch homolog 2 N-terminal-like protein A (NOTCH2NLA) NOTCH family Q7Z3S9
Notch homolog 2 N-terminal-like protein C (NOTCH2NLC) NOTCH family P0DPK4
Keratin-associated protein 11-1 (KRTAP11-1) PMG family Q8IUC1
Protein sprouty homolog 2 (SPRY2) Sprouty family O43597
Brorin (VWC2) . Q2TAL6
Four and a half LIM domains protein 5 (FHL5) . Q5TD97
Gem-associated protein 4 (GEMIN4) . P57678
Heat shock factor 2-binding protein (HSF2BP) . O75031
Keratinocyte proline-rich protein (KPRP) . Q5T749
Sperm mitochondrial-associated cysteine-rich protein (SMCP) . P49901

References

1 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
4 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402