Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name Nap-2  Probe Info 
Probe concentration Probe: 10uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
In Vivo Experiment Model Model Type Living cell
Derived Tissue Breast
Disease Model Invasive breast carcinoma [ICD-11:2C60]
Model Name Human invasive breast carcinoma cells (MCF-7)
Note Negative probe:CC(C)(C)C1=CC=C(C=C1)C(=O)NCCN2C(=O)C3=C4C(=C(C=C3)SC5=CC=C(C=C5)Br)C=CC=C4C2=O

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 5 Protein Related to This Bioclass
Target ID Target Name
 LDTP04999  Actin, aortic smooth muscle (ACTA2)
 LDTP02159  Alpha-enolase (ENO1)
 LDTP04878  Eukaryotic initiation factor 4A-I (EIF4A1)
 LDTP15029  Putative elongation factor 1-alpha-like 3 (EEF1A1P5)
 LDTP07907  Tubulin alpha-1A chain (TUBA1A)
Transporter and channel
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name
 LDTP02815  Desmoplakin (DSP)
 LDTP03107  Filamin-A (FLNA)
 LDTP06549  Hsp90 co-chaperone Cdc37 (CDC37)
Other
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name
 LDTP02756  Junction plakoglobin (JUP)
 LDTP02656  Ribonuclease inhibitor (RNH1)

References

1 Proteome-Wide Identification of On- and Off-Targets of Bcl-2 Inhibitors in Native Biological Systems by Using Affinity-Based Probes (AfBPs). Chembiochem. 2018 Nov 2;19(21):2312-2320. doi: 10.1002/cbic.201800380. Epub 2018 Oct 18.