General Information of Experiment

Probe Name FBP2  Probe Info 
Probe concentration 100 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
LFQ
Competitor Name Tranylcypromine  Competitor Info 
Competitor Concentration 1 mM
In Vivo Experiment Model Model Type Cell lysate
Derived Tissue Cervix uteri
Disease Model Endocervical adenocarcinoma [ICD-11:2C77]
Model Name Human endocervical adenocarcinoma cell lysate (HeLa)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 4 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP02217  Procathepsin L (CTSL) 19.8
 LDTP03109  Amine oxidase [flavin-containing] A (MAOA) 9.2
 LDTP03560  Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) 2.8
 LDTP02074  Aldehyde dehydrogenase, mitochondrial (ALDH2) 2.3
Transporter and channel
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP04663  Bax inhibitor 1 (TMBIM6) 2.9
Other
Click to Show/Hide to Show 4 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP11033  A-kinase anchor protein 9 (AKAP9) 19.7
 LDTP12978  ORM1-like protein 1 (ORMDL1) 3.6
 LDTP17517  Armadillo repeat-containing X-linked protein 2 (ARMCX2) 3.2
 LDTP09196  Biorientation of chromosomes in cell division protein 1-like 1 (BOD1L1) 2.8

References

1 Tranylcypromine specificity for monoamine oxidase is limited by promiscuous protein labelling and lysosomal trapping. RSC Chem Biol. 2020 Aug 12;1(4):209-213. doi: 10.1039/d0cb00048e. eCollection 2020 Oct 1.
Mass spectrometry data entry: PXD018580