Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | Photonaproxen | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | 250 uM | |||||
| Criteria | Qualitation: Labeling site identification | |||||
| Quantitative Method |
Isotope tag
|
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| Experiment Method |
SIM-PAL
|
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| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Chronic myeloid leukemia [ICD-11:2A20] | |||||
| Model Name | Human chronic myeloid leukemia cells (K562) | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Sites | ||||
|---|---|---|---|---|---|---|
| LDTP02072 | Arginase-1 (ARG1) | S94 | ||||
| LDTP02150 | ATP synthase subunit beta, mitochondrial (ATP5F1B) | Y395 | ||||
| LDTP02150 | ATP synthase subunit beta, mitochondrial (ATP5F1B) | D402 | ||||
| LDTP02222 | Bifunctional glutamate/proline--tRNA ligase (EPRS1) | I850 | ||||
| LDTP02222 | Bifunctional glutamate/proline--tRNA ligase (EPRS1) | K1499 | ||||
| LDTP02198 | Cathepsin D (CTSD) | E324 | ||||
| LDTP00701 | D-3-phosphoglycerate dehydrogenase (PHGDH) | N368 | ||||
| LDTP00701 | D-3-phosphoglycerate dehydrogenase (PHGDH) | C369 | ||||
| LDTP00273 | Dynamin-1-like protein (DNM1L) | L424 | ||||
| LDTP02333 | Glutathione S-transferase P (GSTP1) | P197 | ||||
| LDTP02333 | Glutathione S-transferase P (GSTP1) | E198 | ||||
| LDTP00601 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (OGT) | E386 | ||||
Transporter and channel
| Target ID | Target Name | Binding Sites | ||||
|---|---|---|---|---|---|---|
| LDTP02058 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (RPN2) | T613 | ||||
| LDTP02262 | Heat shock protein HSP 90-beta (HSP90AB1) | G689 | ||||
| LDTP02262 | Heat shock protein HSP 90-beta (HSP90AB1) | D691 | ||||
| LDTP00196 | Unconventional myosin-Ic (MYO1C) | L255 | ||||
Transcription factor
| Target ID | Target Name | Binding Sites | ||||
|---|---|---|---|---|---|---|
| LDTP14411 | Nascent polypeptide-associated complex subunit alpha, muscle-specific form (NACA) | I1991 | ||||
| LDTP14411 | Nascent polypeptide-associated complex subunit alpha, muscle-specific form (NACA) | L1994 | ||||
Other
| Target ID | Target Name | Binding Sites | ||||
|---|---|---|---|---|---|---|
| LDTP02053 | Heat shock protein beta-1 (HSPB1) | G53 | ||||
| LDTP01920 | Hemoglobin subunit zeta (HBZ) | T27 | ||||
| LDTP01920 | Hemoglobin subunit zeta (HBZ) | E28 | ||||
| LDTP01920 | Hemoglobin subunit zeta (HBZ) | E31 | ||||
| LDTP01054 | Histone H2B type 1-K (H2BC12) | D69 | ||||
| LDTP01054 | Histone H2B type 1-K (H2BC12) | F71 | ||||
| LDTP01054 | Histone H2B type 1-K (H2BC12) | E72 | ||||
| LDTP01054 | Histone H2B type 1-K (H2BC12) | R73 | ||||
| LDTP02125 | Keratin, type II cytoskeletal 8 (KRT8) | L214 | ||||
| LDTP02125 | Keratin, type II cytoskeletal 8 (KRT8) | E220 | ||||
| LDTP02125 | Keratin, type II cytoskeletal 8 (KRT8) | L356 | ||||
| LDTP02164 | Nucleophosmin (NPM1) | V33 | ||||
| LDTP02164 | Nucleophosmin (NPM1) | D34 | ||||
| LDTP02164 | Nucleophosmin (NPM1) | E39 | ||||
| LDTP02164 | Nucleophosmin (NPM1) | E93 | ||||