Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name Kambe_55  Probe Info 
Probe concentration 10 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
SILAC
Competitor Name Kambe_cp3  Competitor Info 
Competitor Concentration 10 uM
In Vivo Experiment Model Model Type Living cell
Derived Tissue Prostate
Disease Model Prostate carcinoma [ICD-11:2C82]
Model Name Human prostate carcinoma cells (PC-3)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP12013  dCTP pyrophosphatase 1 (DCTPP1) 12.9
 LDTP06645  Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) 6.9
Other
Click to Show/Hide to Show 5 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP13630  Neudesin (NENF) 3.2
 LDTP05076  Tubulin beta-4B chain (TUBB4B) 3.1
 LDTP11233  Tubulin beta-6 chain (TUBB6) 3.1
 LDTP05904  Tubulin beta-3 chain (TUBB3) 3.1
 LDTP11277  Tubulin beta-2B chain (TUBB2B) 3.0

References

1 Mapping the protein interaction landscape for fully functionalized small-molecule probes in human cells. J Am Chem Soc. 2014 Jul 30;136(30):10777-82. doi: 10.1021/ja505517t. Epub 2014 Jul 21.