Details of the Target
General Information of Target
Target ID | LDTP12044 | |||||
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Target Name | 5' exonuclease Apollo (DCLRE1B) | |||||
Gene Name | DCLRE1B | |||||
Gene ID | 64858 | |||||
Synonyms |
SNM1B; 5' exonuclease Apollo; EC 3.1.-.-; Beta-lactamase DCLRE1B; EC 3.5.2.6; DNA cross-link repair 1B protein; SNM1 homolog B; SNMIB; hSNM1B |
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3D Structure | ||||||
Sequence |
MALEVGDMEDGQLSDSDSDMTVAPSDRPLQLPKVLGGDSAMRAFQNTATACAPVSHYRAV
ESVDSSEESFSDSDDDSCLWKRKRQKCFNPPPKPEPFQFGQSSQKPPVAGGKKINNIWGA VLQEQNQDAVATELGILGMEGTIDRSRQSETYNYLLAKKLRKESQEHTKDLDKELDEYMH GGKKMGSKEEENGQGHLKRKRPVKDRLGNRPEMNYKGRYEITAEDSQEKVADEISFRLQE PKKDLIARVVRIIGNKKAIELLMETAEVEQNGGLFIMNGSRRRTPGGVFLNLLKNTPSIS EEQIKDIFYIENQKEYENKKAARKRRTQVLGKKMKQAIKSLNFQEDDDTSRETFASDTNE ALASLDESQEGHAEAKLEAEEAIEVDHSHDLDIF |
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Target Bioclass |
Enzyme
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Family |
DNA repair metallo-beta-lactamase (DRMBL) family
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Subcellular location |
Chromosome, telomere
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Function |
5'-3' exonuclease that plays a central role in telomere maintenance and protection during S-phase. Participates in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair, thereby ensuring that telomeres do not fuse. Plays a key role in telomeric loop (T loop) formation by being recruited by TERF2 at the leading end telomeres and by processing leading-end telomeres immediately after their replication via its exonuclease activity: generates 3' single-stranded overhang at the leading end telomeres avoiding blunt leading-end telomeres that are vulnerable to end-joining reactions and expose the telomere end in a manner that activates the DNA repair pathways. Together with TERF2, required to protect telomeres from replicative damage during replication by controlling the amount of DNA topoisomerase (TOP1, TOP2A and TOP2B) needed for telomere replication during fork passage and prevent aberrant telomere topology. Also involved in response to DNA damage: plays a role in response to DNA interstrand cross-links (ICLs) by facilitating double-strand break formation. In case of spindle stress, involved in prophase checkpoint. Possesses beta-lactamase activity, catalyzing the hydrolysis of penicillin G and nitrocefin. Exhibits no activity towards other beta-lactam antibiotic classes including cephalosporins (cefotaxime) and carbapenems (imipenem).
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Uniprot ID | ||||||
Ensemble ID | ||||||
HGNC ID | ||||||
ChEMBL ID |
Probe(s) Labeling This Target
ABPP Probe
Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
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DBIA Probe Info |
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C416(1.02); C238(1.14) | LDD1507 | [1] | |
NAIA_5 Probe Info |
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N.A. | LDD2225 | [2] | |
IPM Probe Info |
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N.A. | LDD2156 | [3] | |
TFBX Probe Info |
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N.A. | LDD0148 | [4] |
Competitor(s) Related to This Target
Competitor ID | Name | Cell line | Binding Site(Ratio) | Interaction ID | Ref |
---|---|---|---|---|---|
LDCM0214 | AC1 | HEK-293T | C416(1.02); C238(1.14) | LDD1507 | [1] |
LDCM0215 | AC10 | HEK-293T | C416(1.00) | LDD1508 | [1] |
LDCM0226 | AC11 | HEK-293T | C416(1.05) | LDD1509 | [1] |
LDCM0237 | AC12 | HEK-293T | C416(0.98); C238(1.07); C292(1.03) | LDD1510 | [1] |
LDCM0259 | AC14 | HEK-293T | C416(0.97) | LDD1512 | [1] |
LDCM0270 | AC15 | HEK-293T | C416(0.97); C238(1.11); C292(1.06) | LDD1513 | [1] |
LDCM0276 | AC17 | HEK-293T | C416(0.97); C238(1.02) | LDD1515 | [1] |
LDCM0277 | AC18 | HEK-293T | C416(0.99) | LDD1516 | [1] |
LDCM0278 | AC19 | HEK-293T | C416(1.09) | LDD1517 | [1] |
LDCM0279 | AC2 | HEK-293T | C416(1.01) | LDD1518 | [1] |
LDCM0280 | AC20 | HEK-293T | C416(0.92); C238(1.27); C292(1.20) | LDD1519 | [1] |
LDCM0281 | AC21 | HEK-293T | C416(1.04); C149(1.06); C238(0.99) | LDD1520 | [1] |
LDCM0282 | AC22 | HEK-293T | C416(1.09) | LDD1521 | [1] |
LDCM0283 | AC23 | HEK-293T | C416(1.02); C238(1.05); C292(1.16) | LDD1522 | [1] |
LDCM0284 | AC24 | HEK-293T | C416(0.99) | LDD1523 | [1] |
LDCM0285 | AC25 | HEK-293T | C416(0.99); C238(1.07) | LDD1524 | [1] |
LDCM0286 | AC26 | HEK-293T | C416(0.98) | LDD1525 | [1] |
LDCM0287 | AC27 | HEK-293T | C416(1.11) | LDD1526 | [1] |
LDCM0288 | AC28 | HEK-293T | C416(0.82); C238(1.19); C292(1.20) | LDD1527 | [1] |
LDCM0289 | AC29 | HEK-293T | C416(0.89); C149(0.98); C238(1.02) | LDD1528 | [1] |
LDCM0290 | AC3 | HEK-293T | C416(0.98) | LDD1529 | [1] |
LDCM0291 | AC30 | HEK-293T | C416(0.92) | LDD1530 | [1] |
LDCM0292 | AC31 | HEK-293T | C416(1.08); C238(1.14); C292(1.27) | LDD1531 | [1] |
LDCM0293 | AC32 | HEK-293T | C416(1.02) | LDD1532 | [1] |
LDCM0294 | AC33 | HEK-293T | C416(1.12); C238(1.03) | LDD1533 | [1] |
LDCM0295 | AC34 | HEK-293T | C416(1.00) | LDD1534 | [1] |
LDCM0296 | AC35 | HEK-293T | C416(0.95) | LDD1535 | [1] |
LDCM0297 | AC36 | HEK-293T | C416(0.94); C238(1.24); C292(1.02) | LDD1536 | [1] |
LDCM0298 | AC37 | HEK-293T | C416(1.01); C149(1.03); C238(1.02) | LDD1537 | [1] |
LDCM0299 | AC38 | HEK-293T | C416(1.02) | LDD1538 | [1] |
LDCM0300 | AC39 | HEK-293T | C416(0.87); C238(0.99); C292(1.14) | LDD1539 | [1] |
LDCM0301 | AC4 | HEK-293T | C416(1.02); C238(1.10); C292(0.99) | LDD1540 | [1] |
LDCM0302 | AC40 | HEK-293T | C416(1.04) | LDD1541 | [1] |
LDCM0303 | AC41 | HEK-293T | C416(0.99); C238(1.45) | LDD1542 | [1] |
LDCM0304 | AC42 | HEK-293T | C416(1.07) | LDD1543 | [1] |
LDCM0305 | AC43 | HEK-293T | C416(0.90) | LDD1544 | [1] |
LDCM0306 | AC44 | HEK-293T | C416(0.95); C238(1.18); C292(1.00) | LDD1545 | [1] |
LDCM0307 | AC45 | HEK-293T | C416(0.87); C149(1.11); C238(1.08) | LDD1546 | [1] |
LDCM0308 | AC46 | HEK-293T | C416(0.91) | LDD1547 | [1] |
LDCM0309 | AC47 | HEK-293T | C416(0.91); C238(1.07); C292(1.20) | LDD1548 | [1] |
LDCM0310 | AC48 | HEK-293T | C416(1.05) | LDD1549 | [1] |
LDCM0311 | AC49 | HEK-293T | C416(1.12); C238(1.02) | LDD1550 | [1] |
LDCM0312 | AC5 | HEK-293T | C416(0.88); C149(1.04); C238(1.13) | LDD1551 | [1] |
LDCM0313 | AC50 | HEK-293T | C416(1.09) | LDD1552 | [1] |
LDCM0314 | AC51 | HEK-293T | C416(0.91) | LDD1553 | [1] |
LDCM0315 | AC52 | HEK-293T | C416(0.99); C238(1.11); C292(1.05) | LDD1554 | [1] |
LDCM0316 | AC53 | HEK-293T | C416(0.91); C149(0.98); C238(1.07) | LDD1555 | [1] |
LDCM0317 | AC54 | HEK-293T | C416(1.10) | LDD1556 | [1] |
LDCM0318 | AC55 | HEK-293T | C416(0.96); C238(1.06); C292(1.03) | LDD1557 | [1] |
LDCM0319 | AC56 | HEK-293T | C416(1.01) | LDD1558 | [1] |
LDCM0320 | AC57 | HEK-293T | C416(0.94); C238(1.09) | LDD1559 | [1] |
LDCM0321 | AC58 | HEK-293T | C416(0.91) | LDD1560 | [1] |
LDCM0322 | AC59 | HEK-293T | C416(0.99) | LDD1561 | [1] |
LDCM0323 | AC6 | HEK-293T | C416(1.06) | LDD1562 | [1] |
LDCM0324 | AC60 | HEK-293T | C416(0.94); C238(1.23); C292(1.04) | LDD1563 | [1] |
LDCM0325 | AC61 | HEK-293T | C416(0.84); C149(1.01); C238(0.96) | LDD1564 | [1] |
LDCM0326 | AC62 | HEK-293T | C416(1.01) | LDD1565 | [1] |
LDCM0327 | AC63 | HEK-293T | C416(0.96); C238(1.15); C292(1.16) | LDD1566 | [1] |
LDCM0328 | AC64 | HEK-293T | C416(1.01) | LDD1567 | [1] |
LDCM0334 | AC7 | HEK-293T | C416(0.87); C238(1.08); C292(1.25) | LDD1568 | [1] |
LDCM0345 | AC8 | HEK-293T | C416(1.01) | LDD1569 | [1] |
LDCM0248 | AKOS034007472 | HEK-293T | C416(0.97); C149(1.08); C238(1.05) | LDD1511 | [1] |
LDCM0356 | AKOS034007680 | HEK-293T | C416(1.16); C238(1.03) | LDD1570 | [1] |
LDCM0275 | AKOS034007705 | HEK-293T | C416(0.99) | LDD1514 | [1] |
LDCM0632 | CL-Sc | Hep-G2 | C292(0.58) | LDD2227 | [2] |
LDCM0367 | CL1 | HEK-293T | C416(1.01); C149(1.02) | LDD1571 | [1] |
LDCM0368 | CL10 | HEK-293T | C416(1.10) | LDD1572 | [1] |
LDCM0369 | CL100 | HEK-293T | C416(0.82); C149(0.90); C292(0.82) | LDD1573 | [1] |
LDCM0370 | CL101 | HEK-293T | C416(0.90); C149(0.98) | LDD1574 | [1] |
LDCM0371 | CL102 | HEK-293T | C416(1.05); C149(1.16) | LDD1575 | [1] |
LDCM0372 | CL103 | HEK-293T | C416(1.08); C149(0.87); C238(0.99) | LDD1576 | [1] |
LDCM0373 | CL104 | HEK-293T | C416(0.82); C149(1.08); C292(1.03) | LDD1577 | [1] |
LDCM0374 | CL105 | HEK-293T | C416(1.03); C149(0.95) | LDD1578 | [1] |
LDCM0375 | CL106 | HEK-293T | C416(1.07); C149(1.06) | LDD1579 | [1] |
LDCM0376 | CL107 | HEK-293T | C416(1.12); C149(1.05); C238(0.96) | LDD1580 | [1] |
LDCM0377 | CL108 | HEK-293T | C416(0.87); C149(0.90); C292(0.88) | LDD1581 | [1] |
LDCM0378 | CL109 | HEK-293T | C416(0.91); C149(1.00) | LDD1582 | [1] |
LDCM0379 | CL11 | HEK-293T | C416(0.97); C238(1.21); C292(0.88) | LDD1583 | [1] |
LDCM0380 | CL110 | HEK-293T | C416(1.05); C149(1.23) | LDD1584 | [1] |
LDCM0381 | CL111 | HEK-293T | C416(1.13); C149(0.95); C238(1.03) | LDD1585 | [1] |
LDCM0382 | CL112 | HEK-293T | C416(1.05); C149(1.01); C292(1.04) | LDD1586 | [1] |
LDCM0383 | CL113 | HEK-293T | C416(1.03); C149(1.08) | LDD1587 | [1] |
LDCM0384 | CL114 | HEK-293T | C416(1.10); C149(1.12) | LDD1588 | [1] |
LDCM0385 | CL115 | HEK-293T | C416(1.15); C149(1.00); C238(1.02) | LDD1589 | [1] |
LDCM0386 | CL116 | HEK-293T | C416(0.85); C149(0.83); C292(0.96) | LDD1590 | [1] |
LDCM0387 | CL117 | HEK-293T | C416(1.05); C149(0.88) | LDD1591 | [1] |
LDCM0388 | CL118 | HEK-293T | C416(0.97); C149(1.15) | LDD1592 | [1] |
LDCM0389 | CL119 | HEK-293T | C416(1.17); C149(0.93); C238(1.09) | LDD1593 | [1] |
LDCM0390 | CL12 | HEK-293T | C416(1.09) | LDD1594 | [1] |
LDCM0391 | CL120 | HEK-293T | C416(0.85); C149(0.97); C292(0.95) | LDD1595 | [1] |
LDCM0392 | CL121 | HEK-293T | C416(1.11); C149(0.94) | LDD1596 | [1] |
LDCM0393 | CL122 | HEK-293T | C416(0.98); C149(1.07) | LDD1597 | [1] |
LDCM0394 | CL123 | HEK-293T | C416(1.05); C149(0.92); C238(1.25) | LDD1598 | [1] |
LDCM0395 | CL124 | HEK-293T | C416(0.87); C149(1.15); C292(0.90) | LDD1599 | [1] |
LDCM0396 | CL125 | HEK-293T | C416(0.95); C149(0.94) | LDD1600 | [1] |
LDCM0397 | CL126 | HEK-293T | C416(0.99); C149(1.23) | LDD1601 | [1] |
LDCM0398 | CL127 | HEK-293T | C416(1.10); C149(1.04); C238(1.08) | LDD1602 | [1] |
LDCM0399 | CL128 | HEK-293T | C416(0.82); C149(0.98); C292(0.95) | LDD1603 | [1] |
LDCM0400 | CL13 | HEK-293T | C416(1.02); C149(0.96) | LDD1604 | [1] |
LDCM0401 | CL14 | HEK-293T | C416(0.95); C149(1.04) | LDD1605 | [1] |
LDCM0402 | CL15 | HEK-293T | C416(1.30); C149(0.95); C238(1.14) | LDD1606 | [1] |
LDCM0403 | CL16 | HEK-293T | C416(0.82); C149(0.93); C292(1.15) | LDD1607 | [1] |
LDCM0404 | CL17 | HEK-293T | C416(1.14); C238(1.16) | LDD1608 | [1] |
LDCM0405 | CL18 | HEK-293T | C416(1.09) | LDD1609 | [1] |
LDCM0406 | CL19 | HEK-293T | C416(0.98) | LDD1610 | [1] |
LDCM0407 | CL2 | HEK-293T | C416(1.06); C149(1.05) | LDD1611 | [1] |
LDCM0408 | CL20 | HEK-293T | C416(1.06); C238(1.36); C292(1.63) | LDD1612 | [1] |
LDCM0409 | CL21 | HEK-293T | C416(0.90); C149(1.36); C238(1.04) | LDD1613 | [1] |
LDCM0410 | CL22 | HEK-293T | C416(1.19) | LDD1614 | [1] |
LDCM0411 | CL23 | HEK-293T | C416(0.95); C238(1.26); C292(0.81) | LDD1615 | [1] |
LDCM0412 | CL24 | HEK-293T | C416(1.10) | LDD1616 | [1] |
LDCM0413 | CL25 | HEK-293T | C416(0.90); C149(0.52) | LDD1617 | [1] |
LDCM0414 | CL26 | HEK-293T | C416(0.92); C149(1.04) | LDD1618 | [1] |
LDCM0415 | CL27 | HEK-293T | C416(1.05); C149(0.96); C238(1.09) | LDD1619 | [1] |
LDCM0416 | CL28 | HEK-293T | C416(0.85); C149(1.08); C292(0.96) | LDD1620 | [1] |
LDCM0417 | CL29 | HEK-293T | C416(0.95); C238(1.09) | LDD1621 | [1] |
LDCM0418 | CL3 | HEK-293T | C416(1.11); C149(0.89); C238(1.11) | LDD1622 | [1] |
LDCM0419 | CL30 | HEK-293T | C416(1.01) | LDD1623 | [1] |
LDCM0420 | CL31 | HEK-293T | C416(0.96) | LDD1624 | [1] |
LDCM0421 | CL32 | HEK-293T | C416(0.99); C238(1.14); C292(1.44) | LDD1625 | [1] |
LDCM0422 | CL33 | HEK-293T | C416(1.22); C149(1.33); C238(1.10) | LDD1626 | [1] |
LDCM0423 | CL34 | HEK-293T | C416(1.13) | LDD1627 | [1] |
LDCM0424 | CL35 | HEK-293T | C416(1.01); C238(1.27); C292(0.75) | LDD1628 | [1] |
LDCM0425 | CL36 | HEK-293T | C416(1.09) | LDD1629 | [1] |
LDCM0426 | CL37 | HEK-293T | C416(1.08); C149(0.96) | LDD1630 | [1] |
LDCM0428 | CL39 | HEK-293T | C416(1.16); C149(0.76); C238(1.05) | LDD1632 | [1] |
LDCM0429 | CL4 | HEK-293T | C416(0.83); C149(1.00); C292(1.05) | LDD1633 | [1] |
LDCM0430 | CL40 | HEK-293T | C416(0.96); C149(0.99); C292(1.11) | LDD1634 | [1] |
LDCM0431 | CL41 | HEK-293T | C416(1.03); C238(1.25) | LDD1635 | [1] |
LDCM0432 | CL42 | HEK-293T | C416(1.00) | LDD1636 | [1] |
LDCM0433 | CL43 | HEK-293T | C416(1.04) | LDD1637 | [1] |
LDCM0434 | CL44 | HEK-293T | C416(0.97); C238(1.18); C292(1.31) | LDD1638 | [1] |
LDCM0435 | CL45 | HEK-293T | C416(1.34); C149(1.16); C238(1.20) | LDD1639 | [1] |
LDCM0436 | CL46 | HEK-293T | C416(1.06) | LDD1640 | [1] |
LDCM0437 | CL47 | HEK-293T | C416(1.10); C238(1.11); C292(0.76) | LDD1641 | [1] |
LDCM0438 | CL48 | HEK-293T | C416(1.23) | LDD1642 | [1] |
LDCM0439 | CL49 | HEK-293T | C416(0.90); C149(1.11) | LDD1643 | [1] |
LDCM0440 | CL5 | HEK-293T | C416(0.98); C238(1.24) | LDD1644 | [1] |
LDCM0441 | CL50 | HEK-293T | C416(0.91); C149(1.06) | LDD1645 | [1] |
LDCM0443 | CL52 | HEK-293T | C416(0.75); C149(0.97); C292(1.02) | LDD1646 | [1] |
LDCM0444 | CL53 | HEK-293T | C416(0.99); C238(1.24) | LDD1647 | [1] |
LDCM0445 | CL54 | HEK-293T | C416(1.03) | LDD1648 | [1] |
LDCM0446 | CL55 | HEK-293T | C416(1.01) | LDD1649 | [1] |
LDCM0447 | CL56 | HEK-293T | C416(0.96); C238(1.19); C292(1.12) | LDD1650 | [1] |
LDCM0448 | CL57 | HEK-293T | C416(0.85); C149(1.09); C238(1.08) | LDD1651 | [1] |
LDCM0449 | CL58 | HEK-293T | C416(1.19) | LDD1652 | [1] |
LDCM0450 | CL59 | HEK-293T | C416(0.93); C238(1.27); C292(0.83) | LDD1653 | [1] |
LDCM0451 | CL6 | HEK-293T | C416(1.09) | LDD1654 | [1] |
LDCM0452 | CL60 | HEK-293T | C416(1.02) | LDD1655 | [1] |
LDCM0453 | CL61 | HEK-293T | C416(0.91); C149(1.02) | LDD1656 | [1] |
LDCM0454 | CL62 | HEK-293T | C416(0.99); C149(0.93) | LDD1657 | [1] |
LDCM0455 | CL63 | HEK-293T | C416(0.95); C149(1.06); C238(1.06) | LDD1658 | [1] |
LDCM0456 | CL64 | HEK-293T | C416(0.91); C149(1.00); C292(0.96) | LDD1659 | [1] |
LDCM0457 | CL65 | HEK-293T | C416(1.10); C238(1.46) | LDD1660 | [1] |
LDCM0458 | CL66 | HEK-293T | C416(1.01) | LDD1661 | [1] |
LDCM0459 | CL67 | HEK-293T | C416(0.91) | LDD1662 | [1] |
LDCM0460 | CL68 | HEK-293T | C416(0.92); C238(1.18); C292(1.43) | LDD1663 | [1] |
LDCM0461 | CL69 | HEK-293T | C416(0.90); C149(1.01); C238(1.10) | LDD1664 | [1] |
LDCM0462 | CL7 | HEK-293T | C416(0.96) | LDD1665 | [1] |
LDCM0463 | CL70 | HEK-293T | C416(1.10) | LDD1666 | [1] |
LDCM0464 | CL71 | HEK-293T | C416(0.97); C238(1.19); C292(0.81) | LDD1667 | [1] |
LDCM0465 | CL72 | HEK-293T | C416(1.09) | LDD1668 | [1] |
LDCM0466 | CL73 | HEK-293T | C416(1.02); C149(1.09) | LDD1669 | [1] |
LDCM0467 | CL74 | HEK-293T | C416(1.05); C149(1.04) | LDD1670 | [1] |
LDCM0469 | CL76 | HEK-293T | C416(0.95); C149(0.91); C292(0.94) | LDD1672 | [1] |
LDCM0470 | CL77 | HEK-293T | C416(0.97); C238(1.13) | LDD1673 | [1] |
LDCM0471 | CL78 | HEK-293T | C416(0.94) | LDD1674 | [1] |
LDCM0472 | CL79 | HEK-293T | C416(0.97) | LDD1675 | [1] |
LDCM0473 | CL8 | HEK-293T | C416(1.10); C238(1.17); C292(1.51) | LDD1676 | [1] |
LDCM0474 | CL80 | HEK-293T | C416(0.92); C238(1.13); C292(1.51) | LDD1677 | [1] |
LDCM0475 | CL81 | HEK-293T | C416(1.01); C149(1.06); C238(1.36) | LDD1678 | [1] |
LDCM0476 | CL82 | HEK-293T | C416(1.02) | LDD1679 | [1] |
LDCM0477 | CL83 | HEK-293T | C416(0.91); C238(1.21); C292(0.90) | LDD1680 | [1] |
LDCM0478 | CL84 | HEK-293T | C416(1.09) | LDD1681 | [1] |
LDCM0479 | CL85 | HEK-293T | C416(0.81); C149(0.89) | LDD1682 | [1] |
LDCM0480 | CL86 | HEK-293T | C416(0.96); C149(1.17) | LDD1683 | [1] |
LDCM0481 | CL87 | HEK-293T | C416(1.34); C149(0.92); C238(1.00) | LDD1684 | [1] |
LDCM0482 | CL88 | HEK-293T | C416(0.70); C149(0.99); C292(0.95) | LDD1685 | [1] |
LDCM0483 | CL89 | HEK-293T | C416(0.92); C238(1.22) | LDD1686 | [1] |
LDCM0484 | CL9 | HEK-293T | C416(0.86); C149(1.09); C238(1.14) | LDD1687 | [1] |
LDCM0485 | CL90 | HEK-293T | C416(1.11) | LDD1688 | [1] |
LDCM0486 | CL91 | HEK-293T | C416(0.92) | LDD1689 | [1] |
LDCM0487 | CL92 | HEK-293T | C416(1.03); C238(1.25); C292(1.18) | LDD1690 | [1] |
LDCM0488 | CL93 | HEK-293T | C416(0.97); C149(1.18); C238(1.07) | LDD1691 | [1] |
LDCM0489 | CL94 | HEK-293T | C416(1.00) | LDD1692 | [1] |
LDCM0490 | CL95 | HEK-293T | C416(1.35); C238(1.15); C292(0.90) | LDD1693 | [1] |
LDCM0491 | CL96 | HEK-293T | C416(1.09) | LDD1694 | [1] |
LDCM0492 | CL97 | HEK-293T | C416(1.03); C149(1.07) | LDD1695 | [1] |
LDCM0493 | CL98 | HEK-293T | C416(0.91); C149(1.00) | LDD1696 | [1] |
LDCM0494 | CL99 | HEK-293T | C416(1.01); C149(0.98); C238(1.04) | LDD1697 | [1] |
LDCM0495 | E2913 | HEK-293T | C416(1.08); C149(0.99); C238(0.99) | LDD1698 | [1] |
LDCM0468 | Fragment33 | HEK-293T | C416(0.90); C149(0.95); C238(1.02) | LDD1671 | [1] |
LDCM0427 | Fragment51 | HEK-293T | C416(1.07); C149(1.08) | LDD1631 | [1] |
The Interaction Atlas With This Target
The Protein(s) Related To This Target
Enzyme
Protein name | Family | Uniprot ID | |||
---|---|---|---|---|---|
Protein NDRG1 (NDRG1) | NDRG family | Q92597 | |||
Tyrosyl-DNA phosphodiesterase 1 (TDP1) | Tyrosyl-DNA phosphodiesterase family | Q9NUW8 | |||
Ataxin-3 (ATXN3) | . | P54252 |
Transporter and channel
Protein name | Family | Uniprot ID | |||
---|---|---|---|---|---|
Apolipoprotein E (APOE) | Apolipoprotein A1/A4/E family | P02649 | |||
Huntingtin (HTT) | Huntingtin family | P42858 | |||
Wolframin (WFS1) | . | O76024 |
Other
Protein name | Family | Uniprot ID | |||
---|---|---|---|---|---|
Sprouty-related, EVH1 domain-containing protein 1 (SPRED1) | . | Q7Z699 | |||
Telomeric repeat-binding factor 2 (TERF2) | . | Q15554 |
References