Details of the Target

General Information of Target

Target ID LDTP11827
Target Name Translation initiation factor IF-3, mitochondrial (MTIF3)
Gene Name MTIF3
Gene ID 219402
Synonyms
Translation initiation factor IF-3, mitochondrial; IF-3(Mt); IF-3Mt; IF3(mt); IF3mt
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MPKNSKVVKRELDDDVTESVKDLLSNEDAADDAFKTSELIVDGQEEKDTDVEEGSEVEDE
RPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLELS
VGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPWD
QCPLVKNASHTFVEPECEQSSATTYYWYREALNISSSISESGGLNWKMTICLLAAWVMVC
LAMIKGIQSSGKIIYFSSLFPYVVLICFLIRAFLLNGSIDGIRHMFTPKLEIMLEPKVWR
EAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATLVVFAVLGFKA
NVINEKCITQNSETIMKFLKMGNISQDIIPHHINLSTVTAEDYHLVYDIIQKVKEEEFPA
LHLNSCKIEEELNKAVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLVNLGLGSMFGTIE
GIVTPIVDTFKVRKEILTVICCLLAFCIGLIFVQRSGNYFVTMFDDYSATLPLLIVVILE
NIAVCFVYGIDKFMEDLKDMLGFAPSRYYYYMWKYISPLMLLSLLIASVVNMGLSPPGYN
AWIEDKASEEFLSYPTWGLVVCVSLVVFAILPVPVVFIVRRFNLIDDSSGNLASVTYKRG
RVLKEPVNLEGDDTSLIHGKIPSEMPSPNFGKNIYRKQSGSPTLDTAPNGRYGIGYLMAD
IMPDMPESDL
Target Bioclass
Other
Family
IF-3 family
Subcellular location
Mitochondrion
Function
IF-3 binds to the 28S ribosomal subunit and shifts the equilibrium between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins.
Uniprot ID
Q9H2K0
Ensemble ID
ENST00000381116.5
HGNC ID
HGNC:29788

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 5 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IPM
 Probe Info  		N.A.  LDD0241  [1]
DBIA
 Probe Info  		C238(3.25)  LDD3311  [2]
ATP probe
 Probe Info  		N.A.  LDD0199  [3]
IA-alkyne
 Probe Info  		N.A.  LDD0032  [4]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [5]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C238(0.94)  LDD1507  [6]
 LDCM0215  AC10 HEK-293T C238(1.02)  LDD1508  [6]
 LDCM0226  AC11 HEK-293T C238(0.94)  LDD1509  [6]
 LDCM0237  AC12 HEK-293T C238(0.99)  LDD1510  [6]
 LDCM0259  AC14 HEK-293T C238(1.02)  LDD1512  [6]
 LDCM0270  AC15 HEK-293T C238(0.99)  LDD1513  [6]
 LDCM0276  AC17 HEK-293T C238(1.03)  LDD1515  [6]
 LDCM0277  AC18 HEK-293T C238(0.97)  LDD1516  [6]
 LDCM0278  AC19 HEK-293T C238(0.90)  LDD1517  [6]
 LDCM0279  AC2 HEK-293T C238(1.02)  LDD1518  [6]
 LDCM0280  AC20 HEK-293T C238(1.06)  LDD1519  [6]
 LDCM0282  AC22 HEK-293T C238(1.02)  LDD1521  [6]
 LDCM0283  AC23 HEK-293T C238(0.98)  LDD1522  [6]
 LDCM0284  AC24 HEK-293T C238(1.02)  LDD1523  [6]
 LDCM0285  AC25 HEK-293T C238(1.01)  LDD1524  [6]
 LDCM0286  AC26 HEK-293T C238(0.94)  LDD1525  [6]
 LDCM0287  AC27 HEK-293T C238(0.94)  LDD1526  [6]
 LDCM0288  AC28 HEK-293T C238(0.99)  LDD1527  [6]
 LDCM0290  AC3 HEK-293T C238(0.99)  LDD1529  [6]
 LDCM0291  AC30 HEK-293T C238(1.03)  LDD1530  [6]
 LDCM0292  AC31 HEK-293T C238(0.98)  LDD1531  [6]
 LDCM0293  AC32 HEK-293T C238(0.92)  LDD1532  [6]
 LDCM0294  AC33 HEK-293T C238(0.99)  LDD1533  [6]
 LDCM0295  AC34 HEK-293T C238(1.09)  LDD1534  [6]
 LDCM0296  AC35 HEK-293T C238(0.96)  LDD1535  [6]
 LDCM0297  AC36 HEK-293T C238(1.03)  LDD1536  [6]
 LDCM0299  AC38 HEK-293T C238(1.03)  LDD1538  [6]
 LDCM0300  AC39 HEK-293T C238(0.94)  LDD1539  [6]
 LDCM0301  AC4 HEK-293T C238(0.97)  LDD1540  [6]
 LDCM0302  AC40 HEK-293T C238(1.04)  LDD1541  [6]
 LDCM0303  AC41 HEK-293T C238(1.03)  LDD1542  [6]
 LDCM0304  AC42 HEK-293T C238(0.95)  LDD1543  [6]
 LDCM0305  AC43 HEK-293T C238(0.96)  LDD1544  [6]
 LDCM0306  AC44 HEK-293T C238(1.00)  LDD1545  [6]
 LDCM0308  AC46 HEK-293T C238(1.06)  LDD1547  [6]
 LDCM0309  AC47 HEK-293T C238(1.00)  LDD1548  [6]
 LDCM0310  AC48 HEK-293T C238(0.99)  LDD1549  [6]
 LDCM0311  AC49 HEK-293T C238(1.00)  LDD1550  [6]
 LDCM0313  AC50 HEK-293T C238(1.03)  LDD1552  [6]
 LDCM0314  AC51 HEK-293T C238(0.92)  LDD1553  [6]
 LDCM0315  AC52 HEK-293T C238(1.01)  LDD1554  [6]
 LDCM0317  AC54 HEK-293T C238(1.06)  LDD1556  [6]
 LDCM0318  AC55 HEK-293T C238(1.03)  LDD1557  [6]
 LDCM0319  AC56 HEK-293T C238(1.03)  LDD1558  [6]
 LDCM0320  AC57 HEK-293T C238(0.99)  LDD1559  [6]
 LDCM0321  AC58 HEK-293T C238(1.00)  LDD1560  [6]
 LDCM0322  AC59 HEK-293T C238(0.93)  LDD1561  [6]
 LDCM0323  AC6 HEK-293T C238(0.94)  LDD1562  [6]
 LDCM0324  AC60 HEK-293T C238(0.93)  LDD1563  [6]
 LDCM0326  AC62 HEK-293T C238(1.03)  LDD1565  [6]
 LDCM0327  AC63 HEK-293T C238(0.97)  LDD1566  [6]
 LDCM0328  AC64 HEK-293T C238(1.08)  LDD1567  [6]
 LDCM0334  AC7 HEK-293T C238(0.99)  LDD1568  [6]
 LDCM0345  AC8 HEK-293T C238(0.98)  LDD1569  [6]
 LDCM0356  AKOS034007680 HEK-293T C238(0.87)  LDD1570  [6]
 LDCM0275  AKOS034007705 HEK-293T C238(0.97)  LDD1514  [6]
 LDCM0367  CL1 HEK-293T C238(0.97)  LDD1571  [6]
 LDCM0368  CL10 HEK-293T C238(0.97)  LDD1572  [6]
 LDCM0369  CL100 HEK-293T C238(0.94)  LDD1573  [6]
 LDCM0370  CL101 HEK-293T C238(0.77)  LDD1574  [6]
 LDCM0371  CL102 HEK-293T C238(0.93)  LDD1575  [6]
 LDCM0372  CL103 HEK-293T C238(1.10)  LDD1576  [6]
 LDCM0373  CL104 HEK-293T C238(1.03)  LDD1577  [6]
 LDCM0374  CL105 HEK-293T C238(0.97)  LDD1578  [6]
 LDCM0375  CL106 HEK-293T C238(0.90)  LDD1579  [6]
 LDCM0376  CL107 HEK-293T C238(1.10)  LDD1580  [6]
 LDCM0377  CL108 HEK-293T C238(1.01)  LDD1581  [6]
 LDCM0378  CL109 HEK-293T C238(0.95)  LDD1582  [6]
 LDCM0379  CL11 HEK-293T C238(0.96)  LDD1583  [6]
 LDCM0380  CL110 HEK-293T C238(0.92)  LDD1584  [6]
 LDCM0381  CL111 HEK-293T C238(1.03)  LDD1585  [6]
 LDCM0382  CL112 HEK-293T C238(0.98)  LDD1586  [6]
 LDCM0383  CL113 HEK-293T C238(1.01)  LDD1587  [6]
 LDCM0384  CL114 HEK-293T C238(1.00)  LDD1588  [6]
 LDCM0385  CL115 HEK-293T C238(1.10)  LDD1589  [6]
 LDCM0386  CL116 HEK-293T C238(1.01)  LDD1590  [6]
 LDCM0387  CL117 HEK-293T C238(1.02)  LDD1591  [6]
 LDCM0388  CL118 HEK-293T C238(0.99)  LDD1592  [6]
 LDCM0389  CL119 HEK-293T C238(1.15)  LDD1593  [6]
 LDCM0390  CL12 HEK-293T C238(0.98)  LDD1594  [6]
 LDCM0391  CL120 HEK-293T C238(1.03)  LDD1595  [6]
 LDCM0392  CL121 HEK-293T C238(0.82)  LDD1596  [6]
 LDCM0393  CL122 HEK-293T C238(0.95)  LDD1597  [6]
 LDCM0394  CL123 HEK-293T C238(1.02)  LDD1598  [6]
 LDCM0395  CL124 HEK-293T C238(1.05)  LDD1599  [6]
 LDCM0396  CL125 HEK-293T C238(1.05)  LDD1600  [6]
 LDCM0397  CL126 HEK-293T C238(0.93)  LDD1601  [6]
 LDCM0398  CL127 HEK-293T C238(1.08)  LDD1602  [6]
 LDCM0399  CL128 HEK-293T C238(0.98)  LDD1603  [6]
 LDCM0400  CL13 HEK-293T C238(1.04)  LDD1604  [6]
 LDCM0401  CL14 HEK-293T C238(0.95)  LDD1605  [6]
 LDCM0402  CL15 HEK-293T C238(1.03)  LDD1606  [6]
 LDCM0403  CL16 HEK-293T C238(1.00)  LDD1607  [6]
 LDCM0404  CL17 HEK-293T C238(0.88)  LDD1608  [6]
 LDCM0405  CL18 HEK-293T C238(1.05)  LDD1609  [6]
 LDCM0406  CL19 HEK-293T C238(0.90)  LDD1610  [6]
 LDCM0407  CL2 HEK-293T C238(0.86)  LDD1611  [6]
 LDCM0408  CL20 HEK-293T C238(0.93)  LDD1612  [6]
 LDCM0410  CL22 HEK-293T C238(1.00)  LDD1614  [6]
 LDCM0411  CL23 HEK-293T C238(0.92)  LDD1615  [6]
 LDCM0412  CL24 HEK-293T C238(0.96)  LDD1616  [6]
 LDCM0413  CL25 HEK-293T C238(0.93)  LDD1617  [6]
 LDCM0414  CL26 HEK-293T C238(0.97)  LDD1618  [6]
 LDCM0415  CL27 HEK-293T C238(1.09)  LDD1619  [6]
 LDCM0416  CL28 HEK-293T C238(1.02)  LDD1620  [6]
 LDCM0417  CL29 HEK-293T C238(0.98)  LDD1621  [6]
 LDCM0418  CL3 HEK-293T C238(0.96)  LDD1622  [6]
 LDCM0419  CL30 HEK-293T C238(1.03)  LDD1623  [6]
 LDCM0420  CL31 HEK-293T C238(0.91)  LDD1624  [6]
 LDCM0421  CL32 HEK-293T C238(0.94)  LDD1625  [6]
 LDCM0423  CL34 HEK-293T C238(1.02)  LDD1627  [6]
 LDCM0424  CL35 HEK-293T C238(1.08)  LDD1628  [6]
 LDCM0425  CL36 HEK-293T C238(1.02)  LDD1629  [6]
 LDCM0426  CL37 HEK-293T C238(0.92)  LDD1630  [6]
 LDCM0428  CL39 HEK-293T C238(1.06)  LDD1632  [6]
 LDCM0429  CL4 HEK-293T C238(0.83)  LDD1633  [6]
 LDCM0430  CL40 HEK-293T C238(1.02)  LDD1634  [6]
 LDCM0431  CL41 HEK-293T C238(0.97)  LDD1635  [6]
 LDCM0432  CL42 HEK-293T C238(1.09)  LDD1636  [6]
 LDCM0433  CL43 HEK-293T C238(1.10)  LDD1637  [6]
 LDCM0434  CL44 HEK-293T C238(1.13)  LDD1638  [6]
 LDCM0436  CL46 HEK-293T C238(1.06)  LDD1640  [6]
 LDCM0437  CL47 HEK-293T C238(1.07)  LDD1641  [6]
 LDCM0438  CL48 HEK-293T C238(0.99)  LDD1642  [6]
 LDCM0439  CL49 HEK-293T C238(1.04)  LDD1643  [6]
 LDCM0440  CL5 HEK-293T C238(1.00)  LDD1644  [6]
 LDCM0441  CL50 HEK-293T C238(1.07)  LDD1645  [6]
 LDCM0443  CL52 HEK-293T C238(0.96)  LDD1646  [6]
 LDCM0444  CL53 HEK-293T C238(0.97)  LDD1647  [6]
 LDCM0445  CL54 HEK-293T C238(1.04)  LDD1648  [6]
 LDCM0446  CL55 HEK-293T C238(0.97)  LDD1649  [6]
 LDCM0447  CL56 HEK-293T C238(1.11)  LDD1650  [6]
 LDCM0449  CL58 HEK-293T C238(1.07)  LDD1652  [6]
 LDCM0450  CL59 HEK-293T C238(1.09)  LDD1653  [6]
 LDCM0451  CL6 HEK-293T C238(0.84)  LDD1654  [6]
 LDCM0452  CL60 HEK-293T C238(1.12)  LDD1655  [6]
 LDCM0453  CL61 HEK-293T C238(0.97)  LDD1656  [6]
 LDCM0454  CL62 HEK-293T C238(1.06)  LDD1657  [6]
 LDCM0455  CL63 HEK-293T C238(1.07)  LDD1658  [6]
 LDCM0456  CL64 HEK-293T C238(0.96)  LDD1659  [6]
 LDCM0457  CL65 HEK-293T C238(0.95)  LDD1660  [6]
 LDCM0458  CL66 HEK-293T C238(0.98)  LDD1661  [6]
 LDCM0459  CL67 HEK-293T C238(1.01)  LDD1662  [6]
 LDCM0460  CL68 HEK-293T C238(1.07)  LDD1663  [6]
 LDCM0462  CL7 HEK-293T C238(0.89)  LDD1665  [6]
 LDCM0463  CL70 HEK-293T C238(1.13)  LDD1666  [6]
 LDCM0464  CL71 HEK-293T C238(0.96)  LDD1667  [6]
 LDCM0465  CL72 HEK-293T C238(1.01)  LDD1668  [6]
 LDCM0466  CL73 HEK-293T C238(1.05)  LDD1669  [6]
 LDCM0467  CL74 HEK-293T C238(1.05)  LDD1670  [6]
 LDCM0469  CL76 HEK-293T C238(0.97)  LDD1672  [6]
 LDCM0470  CL77 HEK-293T C238(0.92)  LDD1673  [6]
 LDCM0471  CL78 HEK-293T C238(1.11)  LDD1674  [6]
 LDCM0472  CL79 HEK-293T C238(1.08)  LDD1675  [6]
 LDCM0473  CL8 HEK-293T C238(0.95)  LDD1676  [6]
 LDCM0474  CL80 HEK-293T C238(1.04)  LDD1677  [6]
 LDCM0476  CL82 HEK-293T C238(1.22)  LDD1679  [6]
 LDCM0477  CL83 HEK-293T C238(1.05)  LDD1680  [6]
 LDCM0478  CL84 HEK-293T C238(1.08)  LDD1681  [6]
 LDCM0479  CL85 HEK-293T C238(0.92)  LDD1682  [6]
 LDCM0480  CL86 HEK-293T C238(0.97)  LDD1683  [6]
 LDCM0481  CL87 HEK-293T C238(1.06)  LDD1684  [6]
 LDCM0482  CL88 HEK-293T C238(0.99)  LDD1685  [6]
 LDCM0483  CL89 HEK-293T C238(0.98)  LDD1686  [6]
 LDCM0485  CL90 HEK-293T C238(0.87)  LDD1688  [6]
 LDCM0486  CL91 HEK-293T C238(0.96)  LDD1689  [6]
 LDCM0487  CL92 HEK-293T C238(0.98)  LDD1690  [6]
 LDCM0489  CL94 HEK-293T C238(1.06)  LDD1692  [6]
 LDCM0490  CL95 HEK-293T C238(0.92)  LDD1693  [6]
 LDCM0491  CL96 HEK-293T C238(1.02)  LDD1694  [6]
 LDCM0492  CL97 HEK-293T C238(0.89)  LDD1695  [6]
 LDCM0493  CL98 HEK-293T C238(0.85)  LDD1696  [6]
 LDCM0494  CL99 HEK-293T C238(1.07)  LDD1697  [6]
 LDCM0495  E2913 HEK-293T C238(1.11)  LDD1698  [6]
 LDCM0468  Fragment33 HEK-293T C238(1.12)  LDD1671  [6]
 LDCM0427  Fragment51 HEK-293T C238(0.91)  LDD1631  [6]
 LDCM0022  KB02 A101D C238(1.32)  LDD2250  [2]
 LDCM0023  KB03 A101D C238(1.48)  LDD2667  [2]
 LDCM0024  KB05 G361 C238(3.25)  LDD3311  [2]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 10 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
N-acetyltransferase 8 (NAT8) Camello family Q9UHE5
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (CDIPT) CDP-alcohol phosphatidyltransferase class-I family O14735
Phosphatidate cytidylyltransferase 2 (CDS2) CDS family O95674
Cytochrome P450 4F2 (CYP4F2) Cytochrome P450 family P78329
Palmitoyltransferase ZDHHC15 (ZDHHC15) DHHC palmitoyltransferase family Q96MV8
Stearoyl-CoA desaturase (SCD) Fatty acid desaturase type 1 family O00767
Glutathione S-transferase 3, mitochondrial (MGST3) MAPEG family O14880
Atypical kinase COQ8A, mitochondrial (COQ8A) ADCK protein kinase family Q8NI60
E3 ubiquitin-protein ligase SIAH1 (SIAH1) SINA (Seven in absentia) family Q8IUQ4
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) VKOR family Q8N0U8
Transporter and channel
Click To Hide/Show 19 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Bcl-2-like protein 1 (BCL2L1) Bcl-2 family Q07817
Statherin (STATH) Histatin/statherin family P02808
Lysosomal-associated transmembrane protein 4B (LAPTM4B) LAPTM4/LAPTM5 transporter family Q86VI4
Low-density lipoprotein receptor (LDLR) LDLR family P01130
LHFPL tetraspan subfamily member 5 protein (LHFPL5) LHFP family Q8TAF8
B-lymphocyte antigen CD20 (MS4A1) MS4A family P11836
Cardiac phospholamban (PLN) Phospholamban family P26678
Sorting nexin-2 (SNX2) Sorting nexin family O60749
Sperm protein associated with the nucleus on the X chromosome N2 (SPANXN2) SPAN-X family Q5MJ10
Syntaxin-3 (STX3) Syntaxin family Q13277
Syntaxin-6 (STX6) Syntaxin family O43752
Tetraspanin-33 (TSPAN33) Tetraspanin (TM4SF) family Q86UF1
BOS complex subunit TMEM147 (TMEM147) TMEM147 family Q9BVK8
Transmembrane protein 176A (TMEM176A) TMEM176 family Q96HP8
Transmembrane protein 218 (TMEM218) TMEM218 family A2RU14
Transmembrane protein 242 (TMEM242) TMEM242 family Q9NWH2
Sigma intracellular receptor 2 (TMEM97) TMEM97/sigma-2 receptor family Q5BJF2
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF (STRIT1) . P0DN84
Voltage-gated monoatomic cation channel TMEM109 (TMEM109) . Q9BVC6
Transcription factor
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Heat shock transcription factor, X-linked (HSFX1; HSFX2) HSF family Q9UBD0
Zinc finger protein 202 (ZNF202) . O95125
Cytokine and receptor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
C-X-C motif chemokine 9 (CXCL9) Intercrine alpha (chemokine CxC) family Q07325
Other
Click To Hide/Show 29 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
BPI fold-containing family A member 1 (BPIFA1) Plunc family Q9NP55
Apolipoprotein D (APOD) Lipocalin family P05090
Cortexin-3 (CTXN3) Cortexin family Q4LDR2
Cytochrome b-245 chaperone 1 (CYBC1) CYBC1 family Q9BQA9
Fetuin-B (FETUB) Fetuin family Q9UGM5
Integrin beta-2 (ITGB2) Integrin beta chain family P05107
Protein jagunal homolog 1 (JAGN1) Jagunal family Q8N5M9
MORF4 family-associated protein 1 (MRFAP1) MORF4 family-associated protein family Q9Y605
ORM1-like protein 3 (ORMDL3) ORM family Q8N138
Claudin domain-containing protein 2 (CLDND2) PMP-22/EMP/MP20 family Q8NHS1
Stress-associated endoplasmic reticulum protein 1 (SERP1) RAMP4 family Q9Y6X1
Stress-associated endoplasmic reticulum protein 2 (SERP2) RAMP4 family Q8N6R1
Protein reprimo (RPRM) Reprimo family Q9NS64
Selenoprotein K (SELENOK) Selenoprotein K family Q9Y6D0
Vesicle-associated membrane protein 4 (VAMP4) Synaptobrevin family O75379
Bone morphogenetic protein 10 (BMP10) TGF-beta family O95393
Transmembrane protein 11, mitochondrial (TMEM11) TMEM11 family P17152
Transmembrane protein 243 (TMEM243) TMEM243 family Q9BU79
Protein unc-50 homolog (UNC50) Unc-50 family Q53HI1
Protein YIPF6 (YIPF6) YIP1 family Q96EC8
Calcium-binding protein 7 (CABP7) . Q86V35
Cell growth regulator with RING finger domain protein 1 (CGRRF1) . Q99675
Protein TMED8 (TMED8) . Q6PL24
Serine-rich and transmembrane domain-containing protein 1 (SERTM1) . A2A2V5
StAR-related lipid transfer protein 4 (STARD4) . Q96DR4
Thrombomodulin (THBD) . P07204
Thrombospondin type-1 domain-containing protein 7B (THSD7B) . Q9C0I4
Transmembrane protein 254 (TMEM254) . Q8TBM7
Transmembrane protein 42 (TMEM42) . Q69YG0

References

1 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
2 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
3 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
4 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
5 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
6 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402