Details of the Target

General Information of Target

Target ID LDTP10164
Target Name Endosome-associated-trafficking regulator 1 (ENTR1)
Gene Name ENTR1
Gene ID 10807
Synonyms
SDCCAG3; Endosome-associated-trafficking regulator 1; Antigen NY-CO-3; Serologically defined colon cancer antigen 3
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MADAAPQLGKRKRELDVEEAHAASTEEKEAGVGNGTCAPVRLPFSGFRLQKVLRESARDK
IIFLHGKVNEASGDGDGEDAVVILEKTPFQVEQVAQLLTGSPELQLQFSNDIYSTYHLFP
PRQLNDVKTTVVYPATEKHLQKYLRQDLRLIRETGDDYRNITLPHLESQSLSIQWVYNIL
DKKAEADRIVFENPDPSDGFVLIPDLKWNQQQLDDLYLIAICHRRGIRSLRDLTPEHLPL
LRNILHQGQEAILQRYRMKGDHLRVYLHYLPSYYHLHVHFTALGFEAPGSGVERAHLLAE
VIENLECDPRHYQQRTLTFALRADDPLLKLLQEAQQS
Target Bioclass
Other
Family
ENTR1 family
Subcellular location
Cytoplasm
Function
Endosome-associated protein that plays a role in membrane receptor sorting, cytokinesis and ciliogenesis. Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1. Involved in the regulation of cytokinesis; the function may involve PTPN13 and GIT1. Plays a role in the formation of cilia. Involved in cargo protein localization, such as PKD2, at primary cilia. Involved in the presentation of the tumor necrosis factor (TNF) receptor TNFRSF1A on the cell surface, and hence in the modulation of the TNF-induced apoptosis.
Uniprot ID
Q96C92
Ensemble ID
ENST00000298537.11
HGNC ID
HGNC:10667

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 7 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C33(1.09); C39(1.09)  LDD0078  [1]
IA-alkyne
 Probe Info  		N.A.  LDD0165  [2]
TFBX
 Probe Info  		N.A.  LDD0027  [3]
IPM
 Probe Info  		N.A.  LDD0005  [4]
VSF
 Probe Info  		N.A.  LDD0007  [4]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [5]
AOyne
 Probe Info  		15.00  LDD0443  [6]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C371(1.21)  LDD0812  [1]
 LDCM0215  AC10 PaTu 8988t C371(1.95)  LDD1094  [1]
 LDCM0226  AC11 PaTu 8988t C371(1.31)  LDD1105  [1]
 LDCM0230  AC113 HEK-293T C371(1.03)  LDD0828  [1]
 LDCM0231  AC114 HEK-293T C371(0.95)  LDD0829  [1]
 LDCM0232  AC115 HEK-293T C371(1.08)  LDD0830  [1]
 LDCM0233  AC116 HEK-293T C371(1.70)  LDD0831  [1]
 LDCM0234  AC117 HEK-293T C371(1.05)  LDD0832  [1]
 LDCM0235  AC118 HEK-293T C371(1.30)  LDD0833  [1]
 LDCM0236  AC119 HEK-293T C371(1.26)  LDD0834  [1]
 LDCM0237  AC12 PaTu 8988t C371(1.86)  LDD1116  [1]
 LDCM0238  AC120 HEK-293T C371(1.30)  LDD0836  [1]
 LDCM0239  AC121 HEK-293T C371(1.76)  LDD0837  [1]
 LDCM0240  AC122 HEK-293T C371(1.68)  LDD0838  [1]
 LDCM0241  AC123 HEK-293T C371(1.29)  LDD0839  [1]
 LDCM0242  AC124 HEK-293T C371(1.03)  LDD0840  [1]
 LDCM0243  AC125 HEK-293T C371(1.38)  LDD0841  [1]
 LDCM0244  AC126 HEK-293T C371(2.94)  LDD0842  [1]
 LDCM0245  AC127 HEK-293T C371(2.05)  LDD0843  [1]
 LDCM0259  AC14 PaTu 8988t C371(0.89)  LDD1138  [1]
 LDCM0270  AC15 PaTu 8988t C371(1.28)  LDD1149  [1]
 LDCM0276  AC17 HEK-293T C371(1.17); C208(1.36)  LDD1515  [7]
 LDCM0277  AC18 HEK-293T C371(1.14); C208(0.92)  LDD1516  [7]
 LDCM0278  AC19 HEK-293T C371(1.35)  LDD1517  [7]
 LDCM0279  AC2 HEK-293T C371(1.29)  LDD0877  [1]
 LDCM0280  AC20 HEK-293T C371(1.05)  LDD1519  [7]
 LDCM0281  AC21 HEK-293T C371(1.06)  LDD1520  [7]
 LDCM0282  AC22 HEK-293T C371(1.04); C208(1.00)  LDD1521  [7]
 LDCM0283  AC23 HEK-293T C371(1.15); C208(1.12)  LDD1522  [7]
 LDCM0284  AC24 HEK-293T C371(1.00)  LDD1523  [7]
 LDCM0285  AC25 HEK-293T C371(1.05); C208(1.16)  LDD1524  [7]
 LDCM0286  AC26 HEK-293T C371(1.09); C208(0.93)  LDD1525  [7]
 LDCM0287  AC27 HEK-293T C371(1.04)  LDD1526  [7]
 LDCM0288  AC28 HEK-293T C371(1.01)  LDD1527  [7]
 LDCM0289  AC29 HEK-293T C371(1.06)  LDD1528  [7]
 LDCM0290  AC3 HEK-293T C371(1.07)  LDD0888  [1]
 LDCM0291  AC30 HEK-293T C371(1.18); C208(1.13)  LDD1530  [7]
 LDCM0292  AC31 HEK-293T C371(1.17); C208(1.03)  LDD1531  [7]
 LDCM0293  AC32 HEK-293T C371(1.03)  LDD1532  [7]
 LDCM0294  AC33 HEK-293T C371(1.12); C208(1.08)  LDD1533  [7]
 LDCM0295  AC34 HEK-293T C371(1.14); C208(1.21)  LDD1534  [7]
 LDCM0296  AC35 HEK-293T C371(1.05)  LDD1535  [7]
 LDCM0297  AC36 HEK-293T C371(0.99)  LDD1536  [7]
 LDCM0298  AC37 HEK-293T C371(1.03)  LDD1537  [7]
 LDCM0299  AC38 HEK-293T C371(1.20); C208(1.02)  LDD1538  [7]
 LDCM0300  AC39 HEK-293T C371(1.13); C208(1.09)  LDD1539  [7]
 LDCM0301  AC4 HEK-293T C371(1.10)  LDD0899  [1]
 LDCM0302  AC40 HEK-293T C371(1.07)  LDD1541  [7]
 LDCM0303  AC41 HEK-293T C371(1.20); C208(1.07)  LDD1542  [7]
 LDCM0304  AC42 HEK-293T C371(1.17); C208(1.03)  LDD1543  [7]
 LDCM0305  AC43 HEK-293T C371(1.02)  LDD1544  [7]
 LDCM0306  AC44 HEK-293T C371(1.16)  LDD1545  [7]
 LDCM0307  AC45 HEK-293T C371(1.08)  LDD1546  [7]
 LDCM0308  AC46 HEK-293T C371(1.21)  LDD0906  [1]
 LDCM0309  AC47 HEK-293T C371(0.92)  LDD0907  [1]
 LDCM0310  AC48 HEK-293T C371(0.63)  LDD0908  [1]
 LDCM0311  AC49 HEK-293T C371(0.85)  LDD0909  [1]
 LDCM0312  AC5 HEK-293T C371(1.18)  LDD0910  [1]
 LDCM0313  AC50 HEK-293T C371(1.02)  LDD0911  [1]
 LDCM0314  AC51 HEK-293T C371(0.96)  LDD0912  [1]
 LDCM0315  AC52 HEK-293T C371(1.12)  LDD0913  [1]
 LDCM0316  AC53 HEK-293T C371(0.93)  LDD0914  [1]
 LDCM0317  AC54 HEK-293T C371(1.01)  LDD0915  [1]
 LDCM0318  AC55 HEK-293T C371(1.04)  LDD0916  [1]
 LDCM0319  AC56 HEK-293T C371(1.14)  LDD0917  [1]
 LDCM0320  AC57 HEK-293T C371(1.11); C208(1.19)  LDD1559  [7]
 LDCM0321  AC58 HEK-293T C371(1.05); C208(0.89)  LDD1560  [7]
 LDCM0322  AC59 HEK-293T C371(1.06)  LDD1561  [7]
 LDCM0323  AC6 PaTu 8988t C371(1.37)  LDD1202  [1]
 LDCM0324  AC60 HEK-293T C371(1.06)  LDD1563  [7]
 LDCM0325  AC61 HEK-293T C371(0.97)  LDD1564  [7]
 LDCM0326  AC62 HEK-293T C371(1.03); C208(1.20)  LDD1565  [7]
 LDCM0327  AC63 HEK-293T C371(1.14); C208(1.21)  LDD1566  [7]
 LDCM0328  AC64 HEK-293T C371(1.02)  LDD1567  [7]
 LDCM0332  AC68 HEK-293T C371(1.23)  LDD0930  [1]
 LDCM0333  AC69 HEK-293T C371(1.47)  LDD0931  [1]
 LDCM0334  AC7 PaTu 8988t C371(1.39)  LDD1213  [1]
 LDCM0335  AC70 HEK-293T C371(1.30)  LDD0933  [1]
 LDCM0336  AC71 HEK-293T C371(1.32)  LDD0934  [1]
 LDCM0337  AC72 HEK-293T C371(1.59)  LDD0935  [1]
 LDCM0338  AC73 HEK-293T C371(1.59)  LDD0936  [1]
 LDCM0339  AC74 HEK-293T C371(1.54)  LDD0937  [1]
 LDCM0340  AC75 HEK-293T C371(1.51)  LDD0938  [1]
 LDCM0341  AC76 HEK-293T C371(1.21)  LDD0939  [1]
 LDCM0342  AC77 HEK-293T C371(1.37)  LDD0940  [1]
 LDCM0343  AC78 HEK-293T C371(1.73)  LDD0941  [1]
 LDCM0344  AC79 HEK-293T C371(1.54)  LDD0942  [1]
 LDCM0345  AC8 PaTu 8988t C371(1.27)  LDD1224  [1]
 LDCM0346  AC80 HEK-293T C371(1.40)  LDD0944  [1]
 LDCM0347  AC81 HEK-293T C371(1.57)  LDD0945  [1]
 LDCM0348  AC82 HEK-293T C371(1.75)  LDD0946  [1]
 LDCM0248  AKOS034007472 PaTu 8988t C371(1.25)  LDD1127  [1]
 LDCM0356  AKOS034007680 PaTu 8988t C371(1.53)  LDD1235  [1]
 LDCM0275  AKOS034007705 PaTu 8988t C371(1.25)  LDD1154  [1]
 LDCM0020  ARS-1620 HCC44 C33(1.09); C39(1.09)  LDD0078  [1]
 LDCM0367  CL1 PaTu 8988t C371(0.84)  LDD1246  [1]
 LDCM0368  CL10 PaTu 8988t C371(1.07)  LDD1247  [1]
 LDCM0369  CL100 HEK-293T C371(1.77)  LDD0967  [1]
 LDCM0370  CL101 PaTu 8988t C371(1.17)  LDD1249  [1]
 LDCM0371  CL102 PaTu 8988t C371(1.19)  LDD1250  [1]
 LDCM0372  CL103 PaTu 8988t C371(1.33)  LDD1251  [1]
 LDCM0373  CL104 PaTu 8988t C371(0.95)  LDD1252  [1]
 LDCM0374  CL105 HEK-293T C371(0.97)  LDD1578  [7]
 LDCM0375  CL106 HEK-293T C371(1.08); C208(1.06)  LDD1579  [7]
 LDCM0376  CL107 HEK-293T C371(1.05)  LDD1580  [7]
 LDCM0377  CL108 HEK-293T C371(1.06); C208(0.99)  LDD1581  [7]
 LDCM0378  CL109 HEK-293T C371(0.99)  LDD1582  [7]
 LDCM0379  CL11 PaTu 8988t C371(0.80)  LDD1258  [1]
 LDCM0380  CL110 HEK-293T C371(1.12); C208(1.00)  LDD1584  [7]
 LDCM0381  CL111 HEK-293T C371(1.09)  LDD1585  [7]
 LDCM0382  CL112 HEK-293T C371(1.13); C208(1.12)  LDD1586  [7]
 LDCM0383  CL113 HEK-293T C371(1.06)  LDD1587  [7]
 LDCM0384  CL114 HEK-293T C371(1.08); C208(1.19)  LDD1588  [7]
 LDCM0385  CL115 HEK-293T C371(1.22)  LDD1589  [7]
 LDCM0386  CL116 HEK-293T C371(0.97); C208(1.06)  LDD1590  [7]
 LDCM0387  CL117 HEK-293T C371(1.03)  LDD1591  [7]
 LDCM0388  CL118 HEK-293T C371(1.25); C208(1.00)  LDD1592  [7]
 LDCM0389  CL119 HEK-293T C371(1.02)  LDD1593  [7]
 LDCM0390  CL12 PaTu 8988t C371(1.09)  LDD1269  [1]
 LDCM0391  CL120 HEK-293T C371(1.02); C208(1.08)  LDD1595  [7]
 LDCM0392  CL121 HEK-293T C371(1.05)  LDD0990  [1]
 LDCM0393  CL122 HEK-293T C371(0.84)  LDD0991  [1]
 LDCM0394  CL123 HEK-293T C371(0.87)  LDD0992  [1]
 LDCM0395  CL124 HEK-293T C371(1.13)  LDD0993  [1]
 LDCM0396  CL125 HEK-293T C371(1.06)  LDD1600  [7]
 LDCM0397  CL126 HEK-293T C371(1.01); C208(1.10)  LDD1601  [7]
 LDCM0398  CL127 HEK-293T C371(1.04)  LDD1602  [7]
 LDCM0399  CL128 HEK-293T C371(0.94); C208(1.02)  LDD1603  [7]
 LDCM0400  CL13 PaTu 8988t C371(1.14)  LDD1279  [1]
 LDCM0401  CL14 PaTu 8988t C371(1.08)  LDD1280  [1]
 LDCM0402  CL15 PaTu 8988t C371(1.07)  LDD1281  [1]
 LDCM0403  CL16 HEK-293T C371(0.88)  LDD1001  [1]
 LDCM0404  CL17 HEK-293T C371(0.99)  LDD1002  [1]
 LDCM0405  CL18 HEK-293T C371(0.92)  LDD1003  [1]
 LDCM0406  CL19 HEK-293T C371(1.02)  LDD1004  [1]
 LDCM0407  CL2 PaTu 8988t C371(1.02)  LDD1286  [1]
 LDCM0408  CL20 HEK-293T C371(1.05)  LDD1006  [1]
 LDCM0409  CL21 HEK-293T C371(1.21)  LDD1007  [1]
 LDCM0410  CL22 HEK-293T C371(1.01)  LDD1008  [1]
 LDCM0411  CL23 HEK-293T C371(0.93)  LDD1009  [1]
 LDCM0412  CL24 HEK-293T C371(0.78)  LDD1010  [1]
 LDCM0413  CL25 HEK-293T C371(0.89)  LDD1011  [1]
 LDCM0414  CL26 HEK-293T C371(1.09)  LDD1012  [1]
 LDCM0415  CL27 HEK-293T C371(0.92)  LDD1013  [1]
 LDCM0416  CL28 HEK-293T C371(0.98)  LDD1014  [1]
 LDCM0417  CL29 HEK-293T C371(1.00)  LDD1015  [1]
 LDCM0418  CL3 PaTu 8988t C371(1.35)  LDD1297  [1]
 LDCM0419  CL30 HEK-293T C371(1.09)  LDD1017  [1]
 LDCM0420  CL31 PaTu 8988t C371(1.30)  LDD1299  [1]
 LDCM0421  CL32 PaTu 8988t C371(1.77)  LDD1300  [1]
 LDCM0422  CL33 PaTu 8988t C371(1.09)  LDD1301  [1]
 LDCM0423  CL34 PaTu 8988t C371(2.03)  LDD1302  [1]
 LDCM0424  CL35 PaTu 8988t C371(1.21)  LDD1303  [1]
 LDCM0425  CL36 PaTu 8988t C371(1.50)  LDD1304  [1]
 LDCM0426  CL37 PaTu 8988t C371(1.69)  LDD1305  [1]
 LDCM0428  CL39 PaTu 8988t C371(2.45)  LDD1307  [1]
 LDCM0429  CL4 PaTu 8988t C371(1.07)  LDD1308  [1]
 LDCM0430  CL40 PaTu 8988t C371(1.33)  LDD1309  [1]
 LDCM0431  CL41 PaTu 8988t C371(1.25)  LDD1310  [1]
 LDCM0432  CL42 PaTu 8988t C371(2.13)  LDD1311  [1]
 LDCM0433  CL43 PaTu 8988t C371(2.52)  LDD1312  [1]
 LDCM0434  CL44 PaTu 8988t C371(1.22)  LDD1313  [1]
 LDCM0435  CL45 PaTu 8988t C371(1.27)  LDD1314  [1]
 LDCM0436  CL46 HEK-293T C371(1.17)  LDD1034  [1]
 LDCM0437  CL47 HEK-293T C371(0.99)  LDD1035  [1]
 LDCM0438  CL48 HEK-293T C371(0.91)  LDD1036  [1]
 LDCM0439  CL49 HEK-293T C371(1.18)  LDD1037  [1]
 LDCM0440  CL5 PaTu 8988t C371(1.10)  LDD1319  [1]
 LDCM0441  CL50 HEK-293T C371(1.82)  LDD1039  [1]
 LDCM0442  CL51 HEK-293T C371(1.32)  LDD1040  [1]
 LDCM0443  CL52 HEK-293T C371(0.82)  LDD1041  [1]
 LDCM0444  CL53 HEK-293T C371(0.97)  LDD1042  [1]
 LDCM0445  CL54 HEK-293T C371(1.15)  LDD1043  [1]
 LDCM0446  CL55 HEK-293T C371(0.98)  LDD1044  [1]
 LDCM0447  CL56 HEK-293T C371(0.98)  LDD1045  [1]
 LDCM0448  CL57 HEK-293T C371(1.10)  LDD1046  [1]
 LDCM0449  CL58 HEK-293T C371(1.15)  LDD1047  [1]
 LDCM0450  CL59 HEK-293T C371(1.13)  LDD1048  [1]
 LDCM0451  CL6 PaTu 8988t C371(1.05)  LDD1330  [1]
 LDCM0452  CL60 HEK-293T C371(1.05)  LDD1050  [1]
 LDCM0453  CL61 PaTu 8988t C371(1.06)  LDD1332  [1]
 LDCM0454  CL62 PaTu 8988t C371(0.84)  LDD1333  [1]
 LDCM0455  CL63 PaTu 8988t C371(0.95)  LDD1334  [1]
 LDCM0456  CL64 PaTu 8988t C371(1.10)  LDD1335  [1]
 LDCM0457  CL65 PaTu 8988t C371(1.09)  LDD1336  [1]
 LDCM0458  CL66 PaTu 8988t C371(1.12)  LDD1337  [1]
 LDCM0459  CL67 PaTu 8988t C371(1.65)  LDD1338  [1]
 LDCM0460  CL68 PaTu 8988t C371(1.38)  LDD1339  [1]
 LDCM0461  CL69 PaTu 8988t C371(1.21)  LDD1340  [1]
 LDCM0462  CL7 PaTu 8988t C371(1.04)  LDD1341  [1]
 LDCM0463  CL70 PaTu 8988t C371(1.35)  LDD1342  [1]
 LDCM0464  CL71 PaTu 8988t C371(0.94)  LDD1343  [1]
 LDCM0465  CL72 PaTu 8988t C371(0.81)  LDD1344  [1]
 LDCM0466  CL73 PaTu 8988t C371(1.32)  LDD1345  [1]
 LDCM0467  CL74 PaTu 8988t C371(1.03)  LDD1346  [1]
 LDCM0469  CL76 HEK-293T C371(1.05); C208(1.38)  LDD1672  [7]
 LDCM0470  CL77 HEK-293T C371(1.18); C208(1.23)  LDD1673  [7]
 LDCM0471  CL78 HEK-293T C371(1.13); C208(1.02)  LDD1674  [7]
 LDCM0472  CL79 HEK-293T C371(1.18)  LDD1675  [7]
 LDCM0473  CL8 PaTu 8988t C371(1.15)  LDD1352  [1]
 LDCM0474  CL80 HEK-293T C371(1.08)  LDD1677  [7]
 LDCM0475  CL81 HEK-293T C371(1.15)  LDD1678  [7]
 LDCM0476  CL82 HEK-293T C371(1.11); C208(1.13)  LDD1679  [7]
 LDCM0477  CL83 HEK-293T C371(1.13); C208(1.06)  LDD1680  [7]
 LDCM0478  CL84 HEK-293T C371(1.05)  LDD1681  [7]
 LDCM0479  CL85 HEK-293T C371(0.95)  LDD1682  [7]
 LDCM0480  CL86 HEK-293T C371(1.03); C208(1.17)  LDD1683  [7]
 LDCM0481  CL87 HEK-293T C371(0.93)  LDD1684  [7]
 LDCM0482  CL88 HEK-293T C371(0.93); C208(0.96)  LDD1685  [7]
 LDCM0483  CL89 HEK-293T C371(1.17); C208(1.13)  LDD1686  [7]
 LDCM0484  CL9 PaTu 8988t C371(1.04)  LDD1363  [1]
 LDCM0485  CL90 HEK-293T C371(1.55); C208(1.03)  LDD1688  [7]
 LDCM0486  CL91 HEK-293T C371(1.02)  LDD1084  [1]
 LDCM0487  CL92 HEK-293T C371(1.07)  LDD1085  [1]
 LDCM0488  CL93 HEK-293T C371(1.11)  LDD1086  [1]
 LDCM0489  CL94 HEK-293T C371(1.40)  LDD1087  [1]
 LDCM0490  CL95 HEK-293T C371(2.22)  LDD1088  [1]
 LDCM0491  CL96 HEK-293T C371(1.22)  LDD1089  [1]
 LDCM0492  CL97 HEK-293T C371(1.07)  LDD1090  [1]
 LDCM0493  CL98 HEK-293T C371(1.32)  LDD1091  [1]
 LDCM0494  CL99 HEK-293T C371(1.19)  LDD1092  [1]
 LDCM0495  E2913 HEK-293T C371(0.94)  LDD1698  [7]
 LDCM0468  Fragment33 PaTu 8988t C371(1.19)  LDD1347  [1]
 LDCM0427  Fragment51 PaTu 8988t C371(1.73)  LDD1306  [1]
 LDCM0022  KB02 HEK-293T C371(0.94)  LDD1492  [7]
 LDCM0023  KB03 HEK-293T C371(1.03)  LDD1497  [7]
 LDCM0024  KB05 G361 C371(3.52)  LDD3311  [8]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Probable ATP-dependent RNA helicase DDX6 (DDX6) DEAD box helicase family P26196
Transporter and channel
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
AP-1 complex subunit mu-1 (AP1M1) Adaptor complexes medium subunit family Q9BXS5
Syntenin-1 (SDCBP) . O00560

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
2 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
3 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
4 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
5 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
6 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
7 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
8 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840