Details of the Target

General Information of Target

Target ID LDTP08576
Target Name Bardet-Biedl syndrome 7 protein (BBS7)
Gene Name BBS7
Gene ID 55212
Synonyms
BBS2L1; Bardet-Biedl syndrome 7 protein; BBS2-like protein 1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MDLILNRMDYLQVGVTSQKTMKLIPASRHRATQKVVIGDHDGVVMCFGMKKGEAAAVFKT
LPGPKIARLELGGVINTPQEKIFIAAASEIRGFTKRGKQFLSFETNLTESIKAMHISGSD
LFLSASYIYNHYCDCKDQHYYLSGDKINDVICLPVERLSRITPVLACQDRVLRVLQGSDV
MYAVEVPGPPTVLALHNGNGGDSGEDLLFGTSDGKLALIQITTSKPVRKWEIQNEKKRGG
ILCIDSFDIVGDGVKDLLVGRDDGMVEVYSFDNANEPVLRFDQMLSESVTSIQGGCVGKD
SYDEIVVSTYSGWVTGLTTEPIHKESGPGEELKINQEMQNKISSLRNELEHLQYKVLQER
ENYQQSSQSSKAKSAVPSFGINDKFTLNKDDASYSLILEVQTAIDNVLIQSDVPIDLLDV
DKNSAVVSFSSCDSESNDNFLLATYRCQADTTRLELKIRSIEGQYGTLQAYVTPRIQPKT
CQVRQYHIKPLSLHQRTHFIDHDRPMNTLTLTGQFSFAEVHSWVVFCLPEVPEKPPAGEC
VTFYFQNTFLDTQLESTYRKGEGVFKSDNISTISILKDVLSKEATKRKINLNISYEINEV
SVKHTLKLIHPKLEYQLLLAKKVQLIDALKELQIHEGNTNFLIPEYHCILEEADHLQEEY
KKQPAHLERLYGMITDLFIDKFKFKGTNVKTKVPLLLEILDSYDQNALISFFDAA
Target Bioclass
Transporter and channel
Subcellular location
Cell projection, cilium membrane
Function
The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization.
Uniprot ID
Q8IWZ6
Ensemble ID
ENST00000264499.9
HGNC ID
HGNC:18758

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
HCT15 SNV: p.G513D .
IM95 SNV: p.T542I .
SKMEL2 SNV: p.D248N .
SW480 SNV: p.Q514L .
SW756 SNV: p.Q401H .
TF1 SNV: p.S434C .
WM115 SNV: p.V36F .
WM2664 SNV: p.V36F .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 5 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C243(0.90)  LDD1507  [1]
ATP probe
 Probe Info  		N.A.  LDD0199  [2]
IA-alkyne
 Probe Info  		N.A.  LDD0165  [3]
IPM
 Probe Info  		C152(0.00); C167(0.00); C243(0.00)  LDD2156  [4]
AOyne
 Probe Info  		14.20  LDD0443  [5]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C243(0.90)  LDD1507  [1]
 LDCM0215  AC10 HEK-293T C243(1.12); C648(0.92)  LDD1508  [1]
 LDCM0226  AC11 HEK-293T C243(0.95); C648(0.93)  LDD1509  [1]
 LDCM0237  AC12 HEK-293T C243(1.13); C648(0.92)  LDD1510  [1]
 LDCM0259  AC14 HEK-293T C243(0.97); C648(0.89)  LDD1512  [1]
 LDCM0270  AC15 HEK-293T C243(0.93); C648(0.98)  LDD1513  [1]
 LDCM0276  AC17 HEK-293T C243(0.95)  LDD1515  [1]
 LDCM0277  AC18 HEK-293T C243(1.00); C648(1.01)  LDD1516  [1]
 LDCM0278  AC19 HEK-293T C243(0.92); C648(0.84)  LDD1517  [1]
 LDCM0279  AC2 HEK-293T C243(1.04); C648(0.95)  LDD1518  [1]
 LDCM0280  AC20 HEK-293T C243(1.08); C648(0.94)  LDD1519  [1]
 LDCM0281  AC21 HEK-293T C243(0.98)  LDD1520  [1]
 LDCM0282  AC22 HEK-293T C243(0.85); C648(1.12)  LDD1521  [1]
 LDCM0283  AC23 HEK-293T C243(1.13); C648(1.01)  LDD1522  [1]
 LDCM0284  AC24 HEK-293T C243(1.11)  LDD1523  [1]
 LDCM0285  AC25 HEK-293T C243(1.03)  LDD1524  [1]
 LDCM0286  AC26 HEK-293T C243(1.14); C648(0.92)  LDD1525  [1]
 LDCM0287  AC27 HEK-293T C243(0.80); C648(0.98)  LDD1526  [1]
 LDCM0288  AC28 HEK-293T C243(1.03); C648(1.10)  LDD1527  [1]
 LDCM0289  AC29 HEK-293T C243(0.95)  LDD1528  [1]
 LDCM0290  AC3 HEK-293T C243(0.92); C648(0.88)  LDD1529  [1]
 LDCM0291  AC30 HEK-293T C243(0.91); C648(0.85)  LDD1530  [1]
 LDCM0292  AC31 HEK-293T C243(0.91); C648(1.02)  LDD1531  [1]
 LDCM0293  AC32 HEK-293T C243(0.90)  LDD1532  [1]
 LDCM0294  AC33 HEK-293T C243(0.98)  LDD1533  [1]
 LDCM0295  AC34 HEK-293T C243(1.08); C648(0.92)  LDD1534  [1]
 LDCM0296  AC35 HEK-293T C243(1.11); C648(0.84)  LDD1535  [1]
 LDCM0297  AC36 HEK-293T C243(1.05); C648(1.01)  LDD1536  [1]
 LDCM0298  AC37 HEK-293T C243(1.01)  LDD1537  [1]
 LDCM0299  AC38 HEK-293T C243(0.95); C648(0.97)  LDD1538  [1]
 LDCM0300  AC39 HEK-293T C243(0.99); C648(1.00)  LDD1539  [1]
 LDCM0301  AC4 HEK-293T C243(0.86); C648(0.96)  LDD1540  [1]
 LDCM0302  AC40 HEK-293T C243(1.05)  LDD1541  [1]
 LDCM0303  AC41 HEK-293T C243(0.96)  LDD1542  [1]
 LDCM0304  AC42 HEK-293T C243(1.05); C648(0.92)  LDD1543  [1]
 LDCM0305  AC43 HEK-293T C243(0.94); C648(0.86)  LDD1544  [1]
 LDCM0306  AC44 HEK-293T C243(1.11); C648(1.05)  LDD1545  [1]
 LDCM0307  AC45 HEK-293T C243(1.02)  LDD1546  [1]
 LDCM0308  AC46 HEK-293T C243(1.02); C648(0.95)  LDD1547  [1]
 LDCM0309  AC47 HEK-293T C243(1.06); C648(1.08)  LDD1548  [1]
 LDCM0310  AC48 HEK-293T C243(1.03)  LDD1549  [1]
 LDCM0311  AC49 HEK-293T C243(0.97)  LDD1550  [1]
 LDCM0312  AC5 HEK-293T C243(0.95)  LDD1551  [1]
 LDCM0313  AC50 HEK-293T C243(1.01); C648(0.96)  LDD1552  [1]
 LDCM0314  AC51 HEK-293T C243(0.85); C648(0.89)  LDD1553  [1]
 LDCM0315  AC52 HEK-293T C243(1.08); C648(0.95)  LDD1554  [1]
 LDCM0316  AC53 HEK-293T C243(0.94)  LDD1555  [1]
 LDCM0317  AC54 HEK-293T C243(0.87); C648(1.00)  LDD1556  [1]
 LDCM0318  AC55 HEK-293T C243(0.93); C648(1.04)  LDD1557  [1]
 LDCM0319  AC56 HEK-293T C243(0.94)  LDD1558  [1]
 LDCM0320  AC57 HEK-293T C243(0.97)  LDD1559  [1]
 LDCM0321  AC58 HEK-293T C243(1.00); C648(1.08)  LDD1560  [1]
 LDCM0322  AC59 HEK-293T C243(1.12); C648(0.79)  LDD1561  [1]
 LDCM0323  AC6 HEK-293T C243(0.98); C648(0.82)  LDD1562  [1]
 LDCM0324  AC60 HEK-293T C243(1.12); C648(0.84)  LDD1563  [1]
 LDCM0325  AC61 HEK-293T C243(1.02)  LDD1564  [1]
 LDCM0326  AC62 HEK-293T C243(0.96); C648(0.91)  LDD1565  [1]
 LDCM0327  AC63 HEK-293T C243(1.37); C648(1.04)  LDD1566  [1]
 LDCM0328  AC64 HEK-293T C243(0.93)  LDD1567  [1]
 LDCM0334  AC7 HEK-293T C243(0.93); C648(0.93)  LDD1568  [1]
 LDCM0345  AC8 HEK-293T C243(0.88)  LDD1569  [1]
 LDCM0248  AKOS034007472 HEK-293T C243(0.95)  LDD1511  [1]
 LDCM0356  AKOS034007680 HEK-293T C243(1.10)  LDD1570  [1]
 LDCM0275  AKOS034007705 HEK-293T C243(0.97)  LDD1514  [1]
 LDCM0367  CL1 HEK-293T C243(0.56)  LDD1571  [1]
 LDCM0368  CL10 HEK-293T C243(1.12); C648(0.95)  LDD1572  [1]
 LDCM0369  CL100 HEK-293T C243(1.01)  LDD1573  [1]
 LDCM0370  CL101 HEK-293T C243(1.01)  LDD1574  [1]
 LDCM0371  CL102 HEK-293T C243(1.08); C648(1.08)  LDD1575  [1]
 LDCM0372  CL103 HEK-293T C243(1.02)  LDD1576  [1]
 LDCM0373  CL104 HEK-293T C243(0.98)  LDD1577  [1]
 LDCM0374  CL105 HEK-293T C243(0.85)  LDD1578  [1]
 LDCM0375  CL106 HEK-293T C243(1.21); C648(1.37)  LDD1579  [1]
 LDCM0376  CL107 HEK-293T C243(0.90)  LDD1580  [1]
 LDCM0377  CL108 HEK-293T C243(0.90)  LDD1581  [1]
 LDCM0378  CL109 HEK-293T C243(0.84)  LDD1582  [1]
 LDCM0379  CL11 HEK-293T C243(0.99); C648(1.22)  LDD1583  [1]
 LDCM0380  CL110 HEK-293T C243(1.14); C648(1.16)  LDD1584  [1]
 LDCM0381  CL111 HEK-293T C243(0.95)  LDD1585  [1]
 LDCM0382  CL112 HEK-293T C243(0.91)  LDD1586  [1]
 LDCM0383  CL113 HEK-293T C243(0.92)  LDD1587  [1]
 LDCM0384  CL114 HEK-293T C243(1.10); C648(0.92)  LDD1588  [1]
 LDCM0385  CL115 HEK-293T C243(1.07)  LDD1589  [1]
 LDCM0386  CL116 HEK-293T C243(0.97)  LDD1590  [1]
 LDCM0387  CL117 HEK-293T C243(1.16)  LDD1591  [1]
 LDCM0388  CL118 HEK-293T C243(0.98); C648(1.11)  LDD1592  [1]
 LDCM0389  CL119 HEK-293T C243(1.08)  LDD1593  [1]
 LDCM0390  CL12 HEK-293T C243(1.10)  LDD1594  [1]
 LDCM0391  CL120 HEK-293T C243(1.19)  LDD1595  [1]
 LDCM0392  CL121 HEK-293T C243(0.96)  LDD1596  [1]
 LDCM0393  CL122 HEK-293T C243(0.92); C648(1.41)  LDD1597  [1]
 LDCM0394  CL123 HEK-293T C243(0.89)  LDD1598  [1]
 LDCM0395  CL124 HEK-293T C243(0.93)  LDD1599  [1]
 LDCM0396  CL125 HEK-293T C243(0.99)  LDD1600  [1]
 LDCM0397  CL126 HEK-293T C243(1.29); C648(1.16)  LDD1601  [1]
 LDCM0398  CL127 HEK-293T C243(1.06)  LDD1602  [1]
 LDCM0399  CL128 HEK-293T C243(1.09)  LDD1603  [1]
 LDCM0400  CL13 HEK-293T C243(1.05)  LDD1604  [1]
 LDCM0401  CL14 HEK-293T C243(1.31); C648(0.94)  LDD1605  [1]
 LDCM0402  CL15 HEK-293T C243(1.08)  LDD1606  [1]
 LDCM0403  CL16 HEK-293T C243(0.97)  LDD1607  [1]
 LDCM0404  CL17 HEK-293T C243(1.06)  LDD1608  [1]
 LDCM0405  CL18 HEK-293T C243(1.23); C648(0.98)  LDD1609  [1]
 LDCM0406  CL19 HEK-293T C243(1.29); C648(0.92)  LDD1610  [1]
 LDCM0407  CL2 HEK-293T C243(1.45); C648(1.12)  LDD1611  [1]
 LDCM0408  CL20 HEK-293T C243(1.22); C648(1.23)  LDD1612  [1]
 LDCM0409  CL21 HEK-293T C243(1.17)  LDD1613  [1]
 LDCM0410  CL22 HEK-293T C243(1.05); C648(1.33)  LDD1614  [1]
 LDCM0411  CL23 HEK-293T C243(1.51); C648(1.41)  LDD1615  [1]
 LDCM0412  CL24 HEK-293T C243(1.29)  LDD1616  [1]
 LDCM0413  CL25 HEK-293T C243(0.76)  LDD1617  [1]
 LDCM0414  CL26 HEK-293T C243(1.24); C648(0.90)  LDD1618  [1]
 LDCM0415  CL27 HEK-293T C243(0.91)  LDD1619  [1]
 LDCM0416  CL28 HEK-293T C243(0.94)  LDD1620  [1]
 LDCM0417  CL29 HEK-293T C243(0.95)  LDD1621  [1]
 LDCM0418  CL3 HEK-293T C243(1.06)  LDD1622  [1]
 LDCM0419  CL30 HEK-293T C243(1.05); C648(0.95)  LDD1623  [1]
 LDCM0420  CL31 HEK-293T C243(1.06); C648(0.90)  LDD1624  [1]
 LDCM0421  CL32 HEK-293T C243(1.26); C648(1.11)  LDD1625  [1]
 LDCM0422  CL33 HEK-293T C243(0.34)  LDD1626  [1]
 LDCM0423  CL34 HEK-293T C243(1.18); C648(1.31)  LDD1627  [1]
 LDCM0424  CL35 HEK-293T C243(1.28); C648(1.33)  LDD1628  [1]
 LDCM0425  CL36 HEK-293T C243(0.95)  LDD1629  [1]
 LDCM0426  CL37 HEK-293T C243(0.89)  LDD1630  [1]
 LDCM0428  CL39 HEK-293T C243(0.96)  LDD1632  [1]
 LDCM0429  CL4 HEK-293T C243(0.95)  LDD1633  [1]
 LDCM0430  CL40 HEK-293T C243(1.04)  LDD1634  [1]
 LDCM0431  CL41 HEK-293T C243(0.98)  LDD1635  [1]
 LDCM0432  CL42 HEK-293T C243(1.14); C648(0.94)  LDD1636  [1]
 LDCM0433  CL43 HEK-293T C243(1.17); C648(0.95)  LDD1637  [1]
 LDCM0434  CL44 HEK-293T C243(1.03); C648(1.07)  LDD1638  [1]
 LDCM0435  CL45 HEK-293T C243(0.36)  LDD1639  [1]
 LDCM0436  CL46 HEK-293T C243(1.62); C648(1.32)  LDD1640  [1]
 LDCM0437  CL47 HEK-293T C243(1.17); C648(1.47)  LDD1641  [1]
 LDCM0438  CL48 HEK-293T C243(1.05)  LDD1642  [1]
 LDCM0439  CL49 HEK-293T C243(0.96)  LDD1643  [1]
 LDCM0440  CL5 HEK-293T C243(1.27)  LDD1644  [1]
 LDCM0441  CL50 HEK-293T C243(1.19); C648(1.11)  LDD1645  [1]
 LDCM0443  CL52 HEK-293T C243(1.06)  LDD1646  [1]
 LDCM0444  CL53 HEK-293T C243(0.94)  LDD1647  [1]
 LDCM0445  CL54 HEK-293T C243(1.07); C648(1.39)  LDD1648  [1]
 LDCM0446  CL55 HEK-293T C243(1.14); C648(0.92)  LDD1649  [1]
 LDCM0447  CL56 HEK-293T C243(1.21); C648(1.04)  LDD1650  [1]
 LDCM0448  CL57 HEK-293T C243(1.12)  LDD1651  [1]
 LDCM0449  CL58 HEK-293T C243(1.21); C648(1.29)  LDD1652  [1]
 LDCM0450  CL59 HEK-293T C243(1.31); C648(1.31)  LDD1653  [1]
 LDCM0451  CL6 HEK-293T C243(0.99); C648(0.99)  LDD1654  [1]
 LDCM0452  CL60 HEK-293T C243(1.06)  LDD1655  [1]
 LDCM0453  CL61 HEK-293T C243(0.85)  LDD1656  [1]
 LDCM0454  CL62 HEK-293T C243(1.15); C648(1.20)  LDD1657  [1]
 LDCM0455  CL63 HEK-293T C243(1.05)  LDD1658  [1]
 LDCM0456  CL64 HEK-293T C243(0.94)  LDD1659  [1]
 LDCM0457  CL65 HEK-293T C243(1.00)  LDD1660  [1]
 LDCM0458  CL66 HEK-293T C243(1.11); C648(0.99)  LDD1661  [1]
 LDCM0459  CL67 HEK-293T C243(1.00); C648(0.86)  LDD1662  [1]
 LDCM0460  CL68 HEK-293T C243(1.13); C648(1.10)  LDD1663  [1]
 LDCM0461  CL69 HEK-293T C243(0.97)  LDD1664  [1]
 LDCM0462  CL7 HEK-293T C243(1.14); C648(0.93)  LDD1665  [1]
 LDCM0463  CL70 HEK-293T C243(0.85); C648(1.02)  LDD1666  [1]
 LDCM0464  CL71 HEK-293T C243(1.59); C648(1.28)  LDD1667  [1]
 LDCM0465  CL72 HEK-293T C243(1.06)  LDD1668  [1]
 LDCM0466  CL73 HEK-293T C243(0.92)  LDD1669  [1]
 LDCM0467  CL74 HEK-293T C243(1.06); C648(0.98)  LDD1670  [1]
 LDCM0469  CL76 HEK-293T C243(1.05)  LDD1672  [1]
 LDCM0470  CL77 HEK-293T C243(1.02)  LDD1673  [1]
 LDCM0471  CL78 HEK-293T C243(1.12); C648(1.18)  LDD1674  [1]
 LDCM0472  CL79 HEK-293T C243(1.42); C648(0.86)  LDD1675  [1]
 LDCM0473  CL8 HEK-293T C243(1.07); C648(0.95)  LDD1676  [1]
 LDCM0474  CL80 HEK-293T C243(1.17); C648(1.19)  LDD1677  [1]
 LDCM0475  CL81 HEK-293T C243(1.19)  LDD1678  [1]
 LDCM0476  CL82 HEK-293T C243(1.12); C648(1.14)  LDD1679  [1]
 LDCM0477  CL83 HEK-293T C243(1.49); C648(1.42)  LDD1680  [1]
 LDCM0478  CL84 HEK-293T C243(1.27)  LDD1681  [1]
 LDCM0479  CL85 HEK-293T C243(0.75)  LDD1682  [1]
 LDCM0480  CL86 HEK-293T C243(1.29); C648(0.81)  LDD1683  [1]
 LDCM0481  CL87 HEK-293T C243(1.07)  LDD1684  [1]
 LDCM0482  CL88 HEK-293T C243(0.98)  LDD1685  [1]
 LDCM0483  CL89 HEK-293T C243(0.99)  LDD1686  [1]
 LDCM0484  CL9 HEK-293T C243(1.07)  LDD1687  [1]
 LDCM0485  CL90 HEK-293T C243(1.16); C648(1.08)  LDD1688  [1]
 LDCM0486  CL91 HEK-293T C243(1.04); C648(0.83)  LDD1689  [1]
 LDCM0487  CL92 HEK-293T C243(1.05); C648(0.97)  LDD1690  [1]
 LDCM0488  CL93 HEK-293T C243(0.88)  LDD1691  [1]
 LDCM0489  CL94 HEK-293T C243(1.17); C648(1.06)  LDD1692  [1]
 LDCM0490  CL95 HEK-293T C243(1.18); C648(1.16)  LDD1693  [1]
 LDCM0491  CL96 HEK-293T C243(0.93)  LDD1694  [1]
 LDCM0492  CL97 HEK-293T C243(1.05)  LDD1695  [1]
 LDCM0493  CL98 HEK-293T C243(1.16); C648(1.00)  LDD1696  [1]
 LDCM0494  CL99 HEK-293T C243(1.01)  LDD1697  [1]
 LDCM0495  E2913 HEK-293T C243(1.06)  LDD1698  [1]
 LDCM0468  Fragment33 HEK-293T C243(1.07)  LDD1671  [1]
 LDCM0427  Fragment51 HEK-293T C243(1.05); C648(1.07)  LDD1631  [1]
 LDCM0022  KB02 MGG123 C167(2.42)  LDD2469  [6]
 LDCM0023  KB03 MGG123 C167(5.35)  LDD2886  [6]
 LDCM0024  KB05 MGG123 C167(3.48)  LDD3303  [6]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Fructose-bisphosphate aldolase B (ALDOB) Class I fructose-bisphosphate aldolase family P05062
Transporter and channel
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Bardet-Biedl syndrome 1 protein (BBS1) . Q8NFJ9
Bardet-Biedl syndrome 2 protein (BBS2) . Q9BXC9
Transcription factor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Transcription factor Jun (JUN) BZIP family P05412
Other
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Bardet-Biedl syndrome 10 protein (BBS10) TCP-1 chaperonin family Q8TAM1
T-complex protein 1 subunit beta (CCT2) TCP-1 chaperonin family P78371
Bardet-Biedl syndrome 12 protein (BBS12) TCP-1 chaperonin family Q6ZW61
IQ calmodulin-binding motif-containing protein 1 (IQCB1) . Q15051

References

1 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
2 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
3 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
4 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
5 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
6 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840