Details of the Target

General Information of Target

Target ID LDTP05117
Target Name Solute carrier family 35 member B1 (SLC35B1)
Gene Name SLC35B1
Gene ID 10237
Synonyms
UGTREL1; Solute carrier family 35 member B1; ATP/ADP exchanger ER; AXER; Endoplasmic reticulum ATP/ADP translocase; UDP-galactose transporter-related protein 1; UGTrel1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MASSSSLVPDRLRLPLCFLGVFVCYFYYGILQEKITRGKYGEGAKQETFTFALTLVFIQC
VINAVFAKILIQFFDTARVDRTRSWLYAACSISYLGAMVSSNSALQFVNYPTQVLGKSCK
PIPVMLLGVTLLKKKYPLAKYLCVLLIVAGVALFMYKPKKVVGIEEHTVGYGELLLLLSL
TLDGLTGVSQDHMRAHYQTGSNHMMLNINLWSTLLLGMGILFTGELWEFLSFAERYPAII
YNILLFGLTSALGQSFIFMTVVYFGPLTCSIITTTRKFFTILASVILFANPISPMQWVGT
VLVFLGLGLDAKFGKGAKKTSH
Target Bioclass
Transporter and channel
Family
Nucleotide-sugar transporter family, SLC35B subfamily
Subcellular location
Endoplasmic reticulum membrane
Function
ATP:ADP antiporter that catalyzes the exchange of ATP and ADP across the endoplasmic reticulum (ER) membrane. Imports ATP from the cytosol to the ER lumen and exports ADP in the opposite direction. Regulates ER energy metabolism and protein biogenesis. Appears to be part of a calcium-dependent ER to cytosol low energy response axis, where calcium efflux from ER to the cytosol triggers ATP import into the ER lumen to maintain sufficient ATP supply. Provides ATP to ER chaperone HSPA5 that drives protein folding and trafficking in the ER. Can transport dATP, UTP or UDP in exchange for ATP, but the physiological relevance of this process remains to be established.; [Isoform 1]: ATP:ADP antiporter.; [Isoform 2]: ATP:ADP antiporter.
Uniprot ID
P78383
Ensemble ID
ENST00000240333.12
HGNC ID
HGNC:20798

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
HT SNV: p.L153P .
HUPT3 SNV: p.G265S .
MDAMB453 SNV: p.T300S .
TGBC1TKB SNV: p.A139T .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 5 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C156(4.85)  LDD3440  [1]
IA-alkyne
 Probe Info  		N.A.  LDD0036  [2]
IPM
 Probe Info  		N.A.  LDD2156  [3]
TFBX
 Probe Info  		N.A.  LDD0148  [4]
NAIA_5
 Probe Info  		N.A.  LDD2223  [5]
PAL-AfBPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
OEA-DA
 Probe Info  		17.85  LDD0046  [6]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C119(1.02)  LDD1507  [7]
 LDCM0215  AC10 HEK-293T C119(0.93)  LDD1508  [7]
 LDCM0226  AC11 HEK-293T C119(0.91)  LDD1509  [7]
 LDCM0237  AC12 HEK-293T C119(1.03)  LDD1510  [7]
 LDCM0259  AC14 HEK-293T C119(0.99)  LDD1512  [7]
 LDCM0270  AC15 HEK-293T C119(0.95)  LDD1513  [7]
 LDCM0276  AC17 HEK-293T C119(0.95)  LDD1515  [7]
 LDCM0277  AC18 HEK-293T C119(0.92)  LDD1516  [7]
 LDCM0278  AC19 HEK-293T C119(0.75)  LDD1517  [7]
 LDCM0279  AC2 HEK-293T C119(0.95)  LDD1518  [7]
 LDCM0280  AC20 HEK-293T C119(0.93)  LDD1519  [7]
 LDCM0281  AC21 HEK-293T C119(0.94)  LDD1520  [7]
 LDCM0282  AC22 HEK-293T C119(0.97)  LDD1521  [7]
 LDCM0283  AC23 HEK-293T C119(1.18)  LDD1522  [7]
 LDCM0284  AC24 HEK-293T C119(1.02)  LDD1523  [7]
 LDCM0285  AC25 HEK-293T C119(0.96)  LDD1524  [7]
 LDCM0286  AC26 HEK-293T C119(0.93)  LDD1525  [7]
 LDCM0287  AC27 HEK-293T C119(0.89)  LDD1526  [7]
 LDCM0288  AC28 HEK-293T C119(0.95)  LDD1527  [7]
 LDCM0289  AC29 HEK-293T C119(0.91)  LDD1528  [7]
 LDCM0290  AC3 HEK-293T C119(0.86)  LDD1529  [7]
 LDCM0291  AC30 HEK-293T C119(0.97)  LDD1530  [7]
 LDCM0292  AC31 HEK-293T C119(0.93)  LDD1531  [7]
 LDCM0293  AC32 HEK-293T C119(1.06)  LDD1532  [7]
 LDCM0294  AC33 HEK-293T C119(0.93)  LDD1533  [7]
 LDCM0295  AC34 HEK-293T C119(0.96)  LDD1534  [7]
 LDCM0296  AC35 HEK-293T C119(0.85)  LDD1535  [7]
 LDCM0297  AC36 HEK-293T C119(0.98)  LDD1536  [7]
 LDCM0298  AC37 HEK-293T C119(0.94)  LDD1537  [7]
 LDCM0299  AC38 HEK-293T C119(0.94)  LDD1538  [7]
 LDCM0300  AC39 HEK-293T C119(0.93)  LDD1539  [7]
 LDCM0301  AC4 HEK-293T C119(0.99)  LDD1540  [7]
 LDCM0302  AC40 HEK-293T C119(0.97)  LDD1541  [7]
 LDCM0303  AC41 HEK-293T C119(0.97)  LDD1542  [7]
 LDCM0304  AC42 HEK-293T C119(0.89)  LDD1543  [7]
 LDCM0305  AC43 HEK-293T C119(0.81)  LDD1544  [7]
 LDCM0306  AC44 HEK-293T C119(1.01)  LDD1545  [7]
 LDCM0307  AC45 HEK-293T C119(0.93)  LDD1546  [7]
 LDCM0308  AC46 HEK-293T C119(0.92)  LDD1547  [7]
 LDCM0309  AC47 HEK-293T C119(0.91)  LDD1548  [7]
 LDCM0310  AC48 HEK-293T C119(1.06)  LDD1549  [7]
 LDCM0311  AC49 HEK-293T C119(0.94)  LDD1550  [7]
 LDCM0312  AC5 HEK-293T C119(0.97)  LDD1551  [7]
 LDCM0313  AC50 HEK-293T C119(0.94)  LDD1552  [7]
 LDCM0314  AC51 HEK-293T C119(0.87)  LDD1553  [7]
 LDCM0315  AC52 HEK-293T C119(0.97)  LDD1554  [7]
 LDCM0316  AC53 HEK-293T C119(0.93)  LDD1555  [7]
 LDCM0317  AC54 HEK-293T C119(1.00)  LDD1556  [7]
 LDCM0318  AC55 HEK-293T C119(0.88)  LDD1557  [7]
 LDCM0319  AC56 HEK-293T C119(0.95)  LDD1558  [7]
 LDCM0320  AC57 HEK-293T C119(0.98)  LDD1559  [7]
 LDCM0321  AC58 HEK-293T C119(1.09)  LDD1560  [7]
 LDCM0322  AC59 HEK-293T C119(0.86)  LDD1561  [7]
 LDCM0323  AC6 HEK-293T C119(1.02)  LDD1562  [7]
 LDCM0324  AC60 HEK-293T C119(1.00)  LDD1563  [7]
 LDCM0325  AC61 HEK-293T C119(1.00)  LDD1564  [7]
 LDCM0326  AC62 HEK-293T C119(1.05)  LDD1565  [7]
 LDCM0327  AC63 HEK-293T C119(1.03)  LDD1566  [7]
 LDCM0328  AC64 HEK-293T C119(1.05)  LDD1567  [7]
 LDCM0334  AC7 HEK-293T C119(1.02)  LDD1568  [7]
 LDCM0345  AC8 HEK-293T C119(1.01)  LDD1569  [7]
 LDCM0248  AKOS034007472 HEK-293T C119(0.88)  LDD1511  [7]
 LDCM0356  AKOS034007680 HEK-293T C119(0.98)  LDD1570  [7]
 LDCM0275  AKOS034007705 HEK-293T C119(1.00)  LDD1514  [7]
 LDCM0367  CL1 HEK-293T C119(1.02)  LDD1571  [7]
 LDCM0368  CL10 HEK-293T C119(1.89)  LDD1572  [7]
 LDCM0369  CL100 HEK-293T C119(0.99)  LDD1573  [7]
 LDCM0370  CL101 HEK-293T C119(1.02)  LDD1574  [7]
 LDCM0371  CL102 HEK-293T C119(0.96)  LDD1575  [7]
 LDCM0372  CL103 HEK-293T C119(1.08)  LDD1576  [7]
 LDCM0373  CL104 HEK-293T C119(0.98)  LDD1577  [7]
 LDCM0374  CL105 HEK-293T C119(0.91)  LDD1578  [7]
 LDCM0375  CL106 HEK-293T C119(1.02)  LDD1579  [7]
 LDCM0376  CL107 HEK-293T C119(1.03)  LDD1580  [7]
 LDCM0377  CL108 HEK-293T C119(0.94)  LDD1581  [7]
 LDCM0378  CL109 HEK-293T C119(1.03)  LDD1582  [7]
 LDCM0379  CL11 HEK-293T C119(1.04)  LDD1583  [7]
 LDCM0380  CL110 HEK-293T C119(1.05)  LDD1584  [7]
 LDCM0381  CL111 HEK-293T C119(1.02)  LDD1585  [7]
 LDCM0382  CL112 HEK-293T C119(0.91)  LDD1586  [7]
 LDCM0383  CL113 HEK-293T C119(0.94)  LDD1587  [7]
 LDCM0384  CL114 HEK-293T C119(0.98)  LDD1588  [7]
 LDCM0385  CL115 HEK-293T C119(0.99)  LDD1589  [7]
 LDCM0386  CL116 HEK-293T C119(1.00)  LDD1590  [7]
 LDCM0387  CL117 HEK-293T C119(0.92)  LDD1591  [7]
 LDCM0388  CL118 HEK-293T C119(0.98)  LDD1592  [7]
 LDCM0389  CL119 HEK-293T C119(1.03)  LDD1593  [7]
 LDCM0390  CL12 HEK-293T C119(1.13)  LDD1594  [7]
 LDCM0391  CL120 HEK-293T C119(0.93)  LDD1595  [7]
 LDCM0392  CL121 HEK-293T C119(1.00)  LDD1596  [7]
 LDCM0393  CL122 HEK-293T C119(0.92)  LDD1597  [7]
 LDCM0394  CL123 HEK-293T C119(1.09)  LDD1598  [7]
 LDCM0395  CL124 HEK-293T C119(1.00)  LDD1599  [7]
 LDCM0396  CL125 HEK-293T C119(1.09)  LDD1600  [7]
 LDCM0397  CL126 HEK-293T C119(1.03)  LDD1601  [7]
 LDCM0398  CL127 HEK-293T C119(1.10)  LDD1602  [7]
 LDCM0399  CL128 HEK-293T C119(1.02)  LDD1603  [7]
 LDCM0400  CL13 HEK-293T C119(1.10)  LDD1604  [7]
 LDCM0401  CL14 HEK-293T C119(1.07)  LDD1605  [7]
 LDCM0402  CL15 HEK-293T C119(1.05)  LDD1606  [7]
 LDCM0403  CL16 HEK-293T C119(1.05)  LDD1607  [7]
 LDCM0404  CL17 HEK-293T C119(1.03)  LDD1608  [7]
 LDCM0405  CL18 HEK-293T C119(0.97)  LDD1609  [7]
 LDCM0406  CL19 HEK-293T C119(0.91)  LDD1610  [7]
 LDCM0407  CL2 HEK-293T C119(1.05)  LDD1611  [7]
 LDCM0408  CL20 HEK-293T C119(1.03)  LDD1612  [7]
 LDCM0409  CL21 HEK-293T C119(0.96)  LDD1613  [7]
 LDCM0410  CL22 HEK-293T C119(1.05)  LDD1614  [7]
 LDCM0411  CL23 HEK-293T C119(0.97)  LDD1615  [7]
 LDCM0412  CL24 HEK-293T C119(1.04)  LDD1616  [7]
 LDCM0413  CL25 HEK-293T C119(1.28)  LDD1617  [7]
 LDCM0414  CL26 HEK-293T C119(1.10)  LDD1618  [7]
 LDCM0415  CL27 HEK-293T C119(1.11)  LDD1619  [7]
 LDCM0416  CL28 HEK-293T C119(0.95)  LDD1620  [7]
 LDCM0417  CL29 HEK-293T C119(1.11)  LDD1621  [7]
 LDCM0418  CL3 HEK-293T C119(1.15)  LDD1622  [7]
 LDCM0419  CL30 HEK-293T C119(0.96)  LDD1623  [7]
 LDCM0420  CL31 HEK-293T C119(0.82)  LDD1624  [7]
 LDCM0421  CL32 HEK-293T C119(1.01)  LDD1625  [7]
 LDCM0422  CL33 HEK-293T C119(1.18)  LDD1626  [7]
 LDCM0423  CL34 HEK-293T C119(0.98)  LDD1627  [7]
 LDCM0424  CL35 HEK-293T C119(0.97)  LDD1628  [7]
 LDCM0425  CL36 HEK-293T C119(0.96)  LDD1629  [7]
 LDCM0426  CL37 HEK-293T C119(1.15)  LDD1630  [7]
 LDCM0428  CL39 HEK-293T C119(0.97)  LDD1632  [7]
 LDCM0429  CL4 HEK-293T C119(1.10)  LDD1633  [7]
 LDCM0430  CL40 HEK-293T C119(0.98)  LDD1634  [7]
 LDCM0431  CL41 HEK-293T C119(1.01)  LDD1635  [7]
 LDCM0432  CL42 HEK-293T C119(0.94)  LDD1636  [7]
 LDCM0433  CL43 HEK-293T C119(0.85)  LDD1637  [7]
 LDCM0434  CL44 HEK-293T C119(0.91)  LDD1638  [7]
 LDCM0435  CL45 HEK-293T C119(1.42)  LDD1639  [7]
 LDCM0436  CL46 HEK-293T C119(0.87)  LDD1640  [7]
 LDCM0437  CL47 HEK-293T C119(0.86)  LDD1641  [7]
 LDCM0438  CL48 HEK-293T C119(1.01)  LDD1642  [7]
 LDCM0439  CL49 HEK-293T C119(1.16)  LDD1643  [7]
 LDCM0440  CL5 HEK-293T C119(1.10)  LDD1644  [7]
 LDCM0441  CL50 HEK-293T C119(1.09)  LDD1645  [7]
 LDCM0443  CL52 HEK-293T C119(0.94)  LDD1646  [7]
 LDCM0444  CL53 HEK-293T C119(1.05)  LDD1647  [7]
 LDCM0445  CL54 HEK-293T C119(1.09)  LDD1648  [7]
 LDCM0446  CL55 HEK-293T C119(0.84)  LDD1649  [7]
 LDCM0447  CL56 HEK-293T C119(0.94)  LDD1650  [7]
 LDCM0448  CL57 HEK-293T C119(0.77)  LDD1651  [7]
 LDCM0449  CL58 HEK-293T C119(0.97)  LDD1652  [7]
 LDCM0450  CL59 HEK-293T C119(1.03)  LDD1653  [7]
 LDCM0451  CL6 HEK-293T C119(0.96)  LDD1654  [7]
 LDCM0452  CL60 HEK-293T C119(0.97)  LDD1655  [7]
 LDCM0453  CL61 HEK-293T C119(1.16)  LDD1656  [7]
 LDCM0454  CL62 HEK-293T C119(1.02)  LDD1657  [7]
 LDCM0455  CL63 HEK-293T C119(1.03)  LDD1658  [7]
 LDCM0456  CL64 HEK-293T C119(1.01)  LDD1659  [7]
 LDCM0457  CL65 HEK-293T C119(0.94)  LDD1660  [7]
 LDCM0458  CL66 HEK-293T C119(0.86)  LDD1661  [7]
 LDCM0459  CL67 HEK-293T C119(0.83)  LDD1662  [7]
 LDCM0460  CL68 HEK-293T C119(0.95)  LDD1663  [7]
 LDCM0461  CL69 HEK-293T C119(0.88)  LDD1664  [7]
 LDCM0462  CL7 HEK-293T C119(0.90)  LDD1665  [7]
 LDCM0463  CL70 HEK-293T C119(0.95)  LDD1666  [7]
 LDCM0464  CL71 HEK-293T C119(0.94)  LDD1667  [7]
 LDCM0465  CL72 HEK-293T C119(1.03)  LDD1668  [7]
 LDCM0466  CL73 HEK-293T C119(1.07)  LDD1669  [7]
 LDCM0467  CL74 HEK-293T C119(1.06)  LDD1670  [7]
 LDCM0469  CL76 HEK-293T C119(0.99)  LDD1672  [7]
 LDCM0470  CL77 HEK-293T C119(1.00)  LDD1673  [7]
 LDCM0471  CL78 HEK-293T C119(0.97)  LDD1674  [7]
 LDCM0472  CL79 HEK-293T C119(0.87)  LDD1675  [7]
 LDCM0473  CL8 HEK-293T C119(1.97)  LDD1676  [7]
 LDCM0474  CL80 HEK-293T C119(0.98)  LDD1677  [7]
 LDCM0475  CL81 HEK-293T C119(0.94)  LDD1678  [7]
 LDCM0476  CL82 HEK-293T C119(0.91)  LDD1679  [7]
 LDCM0477  CL83 HEK-293T C119(0.80)  LDD1680  [7]
 LDCM0478  CL84 HEK-293T C119(0.97)  LDD1681  [7]
 LDCM0479  CL85 HEK-293T C119(1.29)  LDD1682  [7]
 LDCM0480  CL86 HEK-293T C119(1.25)  LDD1683  [7]
 LDCM0481  CL87 HEK-293T C119(1.05)  LDD1684  [7]
 LDCM0482  CL88 HEK-293T C119(1.10)  LDD1685  [7]
 LDCM0483  CL89 HEK-293T C119(1.07)  LDD1686  [7]
 LDCM0484  CL9 HEK-293T C119(1.03)  LDD1687  [7]
 LDCM0485  CL90 HEK-293T C119(1.36)  LDD1688  [7]
 LDCM0486  CL91 HEK-293T C119(0.89)  LDD1689  [7]
 LDCM0487  CL92 HEK-293T C119(0.99)  LDD1690  [7]
 LDCM0488  CL93 HEK-293T C119(0.85)  LDD1691  [7]
 LDCM0489  CL94 HEK-293T C119(1.04)  LDD1692  [7]
 LDCM0490  CL95 HEK-293T C119(1.34)  LDD1693  [7]
 LDCM0491  CL96 HEK-293T C119(1.20)  LDD1694  [7]
 LDCM0492  CL97 HEK-293T C119(1.14)  LDD1695  [7]
 LDCM0493  CL98 HEK-293T C119(1.04)  LDD1696  [7]
 LDCM0494  CL99 HEK-293T C119(1.12)  LDD1697  [7]
 LDCM0495  E2913 HEK-293T C119(1.04)  LDD1698  [7]
 LDCM0625  F8 Ramos C119(1.01)  LDD2187  [8]
 LDCM0582  Fragment23 Ramos C119(2.02)  LDD2196  [8]
 LDCM0578  Fragment27 Ramos C119(0.76)  LDD2197  [8]
 LDCM0586  Fragment28 Ramos C119(0.96)  LDD2198  [8]
 LDCM0588  Fragment30 Ramos C119(0.58)  LDD2199  [8]
 LDCM0468  Fragment33 HEK-293T C119(1.01)  LDD1671  [7]
 LDCM0566  Fragment4 Ramos C119(12.38)  LDD2184  [8]
 LDCM0427  Fragment51 HEK-293T C119(1.07)  LDD1631  [7]
 LDCM0569  Fragment7 Ramos C119(2.88)  LDD2186  [8]
 LDCM0022  KB02 HEK-293T C119(1.02)  LDD1492  [7]
 LDCM0023  KB03 HEK-293T C119(1.04)  LDD1497  [7]
 LDCM0024  KB05 SNU-245 C156(4.85)  LDD3440  [1]
 LDCM0627  NUDT7-COV-1 HEK-293T C119(1.27)  LDD2206  [9]
 LDCM0628  OTUB2-COV-1 HEK-293T C119(0.32)  LDD2207  [9]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Tyrosine-protein phosphatase non-receptor type 5 (PTPN5) Protein-tyrosine phosphatase family P54829
ADP-ribosylation factor-like protein 13B (ARL13B) Arf family Q3SXY8
Peptidyl-prolyl cis-trans isomerase FKBP8 (FKBP8) . Q14318
Transporter and channel
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Aquaporin-6 (AQP6) MIP/aquaporin (TC 1.A.8) family Q13520
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3) NIP3 family Q12983
Vesicle-associated membrane protein-associated protein A (VAPA) VAMP-associated protein (VAP) (TC 9.B.17) family Q9P0L0
Transcription factor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cyclic AMP-responsive element-binding protein 3-like protein 1 (CREB3L1) BZIP family Q96BA8
GPCR
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Probable G-protein coupled receptor 152 (GPR152) G-protein coupled receptor 1 family Q8TDT2
Frizzled-5 (FZD5) G-protein coupled receptor Fz/Smo family Q13467
Immunoglobulin
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
B-cell antigen receptor complex-associated protein alpha chain (CD79A) . P11912
V-type immunoglobulin domain-containing suppressor of T-cell activation (VSIR) . Q9H7M9
Other
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Coiled-coil domain-containing protein 107 (CCDC107) . Q8WV48
PDZK1-interacting protein 1 (PDZK1IP1) . Q13113

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
2 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
3 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
4 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
5 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
6 Mapping Protein Targets of Bioactive Small Molecules Using Lipid-Based Chemical Proteomics. ACS Chem Biol. 2017 Oct 20;12(10):2671-2681. doi: 10.1021/acschembio.7b00581. Epub 2017 Sep 20.
Mass spectrometry data entry: PXD007570
7 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
8 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
9 Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening. J Am Chem Soc. 2019 Jun 5;141(22):8951-8968. doi: 10.1021/jacs.9b02822. Epub 2019 May 22.