General Information of Target

Target ID LDTP03996
Target Name Leukemia inhibitory factor receptor (LIFR)
Gene Name LIFR
Gene ID 3977
Synonyms
Leukemia inhibitory factor receptor; LIF receptor; LIF-R; CD antigen CD118
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MMDIYVCLKRPSWMVDNKRMRTASNFQWLLSTFILLYLMNQVNSQKKGAPHDLKCVTNNL
QVWNCSWKAPSGTGRGTDYEVCIENRSRSCYQLEKTSIKIPALSHGDYEITINSLHDFGS
STSKFTLNEQNVSLIPDTPEILNLSADFSTSTLYLKWNDRGSVFPHRSNVIWEIKVLRKE
SMELVKLVTHNTTLNGKDTLHHWSWASDMPLECAIHFVEIRCYIDNLHFSGLEEWSDWSP
VKNISWIPDSQTKVFPQDKVILVGSDITFCCVSQEKVLSALIGHTNCPLIHLDGENVAIK
IRNISVSASSGTNVVFTTEDNIFGTVIFAGYPPDTPQQLNCETHDLKEIICSWNPGRVTA
LVGPRATSYTLVESFSGKYVRLKRAEAPTNESYQLLFQMLPNQEIYNFTLNAHNPLGRSQ
STILVNITEKVYPHTPTSFKVKDINSTAVKLSWHLPGNFAKINFLCEIEIKKSNSVQEQR
NVTIKGVENSSYLVALDKLNPYTLYTFRIRCSTETFWKWSKWSNKKQHLTTEASPSKGPD
TWREWSSDGKNLIIYWKPLPINEANGKILSYNVSCSSDEETQSLSEIPDPQHKAEIRLDK
NDYIISVVAKNSVGSSPPSKIASMEIPNDDLKIEQVVGMGKGILLTWHYDPNMTCDYVIK
WCNSSRSEPCLMDWRKVPSNSTETVIESDEFRPGIRYNFFLYGCRNQGYQLLRSMIGYIE
ELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGYLFYFGKGERDTSKMRVLESGR
SDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGVGPEKSMYVVTKENSVGLIIAI
LIPVAVAVIVGVVTSILCYRKREWIKETFYPDIPNPENCKALQFQKSVCEGSSALKTLEM
NPCTPNNVEVLETRSAFPKIEDTEIISPVAERPEDRSDAEPENHVVVSYCPPIIEEEIPN
PAADEAGGTAQVIYIDVQSMYQPQAKPEEEQENDPVGGAGYKPQMHLPINSTVEDIAAEE
DLDKTAGYRPQANVNTWNLVSPDSPRSIDSNSEIVSFGSPCSINSRQFLIPPKDEDSPKS
NGGGWSFTNFFQNKPND
Target Type
Clinical trial
Target Bioclass
Cytokine and receptor
Family
Type I cytokine receptor family, Type 2 subfamily
Subcellular location
Secreted; Cell membrane
Function Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells.
TTD ID
T96894
Uniprot ID
P42702
DrugMap ID
TTID542
Ensemble ID
ENST00000263409.8
HGNC ID
HGNC:6597

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
22RV1 Deletion: p.L756Ter .
42MGBA SNV: p.V910F .
A2058 SNV: p.D922G .
CAL27 SNV: p.R75C .
COLO678 SNV: p.G1084R .
GB1 SNV: p.P415S .
HCT15 SNV: p.H528Y .
HEC1 SNV: p.K276T .
HEC1B SNV: p.K276T .
HT115 SNV: p.T854A .
LN229 SNV: p.P1060A .
LNCaP clone FGC SNV: p.S239N .
MFE296 Deletion: p.K526NfsTer4 .
MOLT4 SNV: p.A985T .
RL952 SNV: p.V380I .
SKMEL24 SNV: p.G356E .
SNU869 SNV: p.S1059N .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info 
C90(1.99)  LDD3368  [1]
IPM
 Probe Info 
C903(0.00); C1061(0.00); C889(0.00)  LDD0147  [2]
TFBX
 Probe Info 
N.A.  LDD0148  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C655(1.19); C287(0.99)  LDD1507  [3]
 LDCM0226  AC11 HEK-293T C655(0.85); C287(1.14); C903(1.02)  LDD1509  [3]
 LDCM0237  AC12 HEK-293T C655(1.24); C287(1.08); C903(0.99)  LDD1510  [3]
 LDCM0259  AC14 HEK-293T C655(1.13); C287(0.96); C903(0.94)  LDD1512  [3]
 LDCM0270  AC15 HEK-293T C655(0.81); C287(1.03); C903(0.85); C889(0.93)  LDD1513  [3]
 LDCM0276  AC17 HEK-293T C655(1.27); C287(1.00)  LDD1515  [3]
 LDCM0278  AC19 HEK-293T C655(1.36); C287(1.00); C903(1.49)  LDD1517  [3]
 LDCM0280  AC20 HEK-293T C655(1.24); C287(0.99); C903(0.92)  LDD1519  [3]
 LDCM0281  AC21 HEK-293T C287(1.02)  LDD1520  [3]
 LDCM0282  AC22 HEK-293T C655(1.22); C287(0.96); C903(0.89)  LDD1521  [3]
 LDCM0283  AC23 HEK-293T C655(0.77); C287(0.94); C903(1.00); C889(0.98)  LDD1522  [3]
 LDCM0284  AC24 HEK-293T C287(1.13); C82(0.93); C1061(1.10)  LDD1523  [3]
 LDCM0285  AC25 HEK-293T C655(1.24); C287(1.09)  LDD1524  [3]
 LDCM0287  AC27 HEK-293T C655(0.69); C287(1.13); C903(0.92)  LDD1526  [3]
 LDCM0288  AC28 HEK-293T C655(1.26); C287(1.05); C903(0.90)  LDD1527  [3]
 LDCM0289  AC29 HEK-293T C287(1.18)  LDD1528  [3]
 LDCM0290  AC3 HEK-293T C655(1.25); C287(0.98); C903(1.09)  LDD1529  [3]
 LDCM0291  AC30 HEK-293T C655(1.11); C287(1.00); C903(1.04)  LDD1530  [3]
 LDCM0292  AC31 HEK-293T C655(0.89); C287(1.08); C903(0.99); C889(0.91)  LDD1531  [3]
 LDCM0293  AC32 HEK-293T C287(1.15); C82(1.14); C1061(0.85)  LDD1532  [3]
 LDCM0294  AC33 HEK-293T C655(1.47); C287(1.00)  LDD1533  [3]
 LDCM0296  AC35 HEK-293T C655(0.69); C287(0.84); C903(0.95)  LDD1535  [3]
 LDCM0297  AC36 HEK-293T C655(1.40); C287(1.01); C903(1.05)  LDD1536  [3]
 LDCM0298  AC37 HEK-293T C287(1.06)  LDD1537  [3]
 LDCM0299  AC38 HEK-293T C655(1.09); C287(0.97); C903(0.90)  LDD1538  [3]
 LDCM0300  AC39 HEK-293T C655(1.07); C287(0.97); C903(0.97); C889(0.93)  LDD1539  [3]
 LDCM0301  AC4 HEK-293T C655(1.04); C287(1.00); C903(1.01)  LDD1540  [3]
 LDCM0302  AC40 HEK-293T C287(1.12); C82(0.86); C1061(1.01)  LDD1541  [3]
 LDCM0303  AC41 HEK-293T C655(1.10); C287(1.10)  LDD1542  [3]
 LDCM0305  AC43 HEK-293T C655(1.38); C287(0.84); C903(0.97)  LDD1544  [3]
 LDCM0306  AC44 HEK-293T C655(0.87); C287(1.02); C903(1.05)  LDD1545  [3]
 LDCM0307  AC45 HEK-293T C287(1.06)  LDD1546  [3]
 LDCM0308  AC46 HEK-293T C655(1.09); C287(0.92); C903(1.15)  LDD1547  [3]
 LDCM0309  AC47 HEK-293T C655(0.88); C287(1.07); C903(0.89); C889(0.95)  LDD1548  [3]
 LDCM0310  AC48 HEK-293T C287(1.10); C82(1.04); C1061(1.16)  LDD1549  [3]
 LDCM0311  AC49 HEK-293T C655(1.26); C287(0.95)  LDD1550  [3]
 LDCM0312  AC5 HEK-293T C287(1.20)  LDD1551  [3]
 LDCM0314  AC51 HEK-293T C655(0.75); C287(0.99); C903(0.91)  LDD1553  [3]
 LDCM0315  AC52 HEK-293T C655(0.87); C287(0.98); C903(0.93)  LDD1554  [3]
 LDCM0316  AC53 HEK-293T C287(1.18)  LDD1555  [3]
 LDCM0317  AC54 HEK-293T C655(1.10); C287(0.95); C903(1.04)  LDD1556  [3]
 LDCM0318  AC55 HEK-293T C655(0.58); C287(0.94); C903(0.96); C889(0.91)  LDD1557  [3]
 LDCM0319  AC56 HEK-293T C287(1.13); C82(1.25); C1061(0.96)  LDD1558  [3]
 LDCM0320  AC57 HEK-293T C655(1.58); C287(1.09)  LDD1559  [3]
 LDCM0322  AC59 HEK-293T C655(0.76); C287(1.03); C903(0.91)  LDD1561  [3]
 LDCM0323  AC6 HEK-293T C655(0.98); C287(0.97); C903(0.95)  LDD1562  [3]
 LDCM0324  AC60 HEK-293T C655(0.86); C287(1.10); C903(1.10)  LDD1563  [3]
 LDCM0325  AC61 HEK-293T C287(1.14)  LDD1564  [3]
 LDCM0326  AC62 HEK-293T C655(1.18); C287(0.97); C903(0.88)  LDD1565  [3]
 LDCM0327  AC63 HEK-293T C655(1.08); C287(1.03); C903(1.14); C889(0.94)  LDD1566  [3]
 LDCM0328  AC64 HEK-293T C287(1.14); C82(0.84); C1061(1.09)  LDD1567  [3]
 LDCM0334  AC7 HEK-293T C655(0.63); C287(1.08); C903(0.99); C889(0.89)  LDD1568  [3]
 LDCM0345  AC8 HEK-293T C287(1.23); C82(1.01); C1061(0.98)  LDD1569  [3]
 LDCM0248  AKOS034007472 HEK-293T C287(1.10)  LDD1511  [3]
 LDCM0356  AKOS034007680 HEK-293T C655(1.21); C287(1.18)  LDD1570  [3]
 LDCM0275  AKOS034007705 HEK-293T C287(1.29); C82(0.90); C1061(1.05)  LDD1514  [3]
 LDCM0367  CL1 HEK-293T C879(1.23); C287(1.27)  LDD1571  [3]
 LDCM0368  CL10 HEK-293T C655(1.24); C287(1.83); C903(1.15)  LDD1572  [3]
 LDCM0369  CL100 HEK-293T C287(1.40)  LDD1573  [3]
 LDCM0370  CL101 HEK-293T C879(1.18); C287(1.05)  LDD1574  [3]
 LDCM0371  CL102 HEK-293T C903(0.73)  LDD1575  [3]
 LDCM0372  CL103 HEK-293T C903(1.07)  LDD1576  [3]
 LDCM0373  CL104 HEK-293T C287(1.20)  LDD1577  [3]
 LDCM0374  CL105 HEK-293T C879(1.12); C287(1.03)  LDD1578  [3]
 LDCM0375  CL106 HEK-293T C903(0.91)  LDD1579  [3]
 LDCM0376  CL107 HEK-293T C903(1.09)  LDD1580  [3]
 LDCM0377  CL108 HEK-293T C287(1.02)  LDD1581  [3]
 LDCM0378  CL109 HEK-293T C879(1.09); C287(1.13)  LDD1582  [3]
 LDCM0379  CL11 HEK-293T C655(1.08); C287(1.50); C903(0.88); C889(0.91)  LDD1583  [3]
 LDCM0380  CL110 HEK-293T C903(0.80)  LDD1584  [3]
 LDCM0381  CL111 HEK-293T C903(1.22)  LDD1585  [3]
 LDCM0382  CL112 HEK-293T C287(1.21)  LDD1586  [3]
 LDCM0383  CL113 HEK-293T C879(1.04); C287(0.99)  LDD1587  [3]
 LDCM0384  CL114 HEK-293T C903(0.89)  LDD1588  [3]
 LDCM0385  CL115 HEK-293T C903(1.07)  LDD1589  [3]
 LDCM0386  CL116 HEK-293T C287(1.17)  LDD1590  [3]
 LDCM0387  CL117 HEK-293T C879(1.05); C287(1.00)  LDD1591  [3]
 LDCM0388  CL118 HEK-293T C903(0.96)  LDD1592  [3]
 LDCM0389  CL119 HEK-293T C903(0.73)  LDD1593  [3]
 LDCM0390  CL12 HEK-293T C287(1.61); C82(0.90); C1061(1.09)  LDD1594  [3]
 LDCM0391  CL120 HEK-293T C287(1.12)  LDD1595  [3]
 LDCM0392  CL121 HEK-293T C879(1.04); C287(1.09)  LDD1596  [3]
 LDCM0393  CL122 HEK-293T C903(0.94)  LDD1597  [3]
 LDCM0394  CL123 HEK-293T C903(0.81)  LDD1598  [3]
 LDCM0395  CL124 HEK-293T C287(1.21)  LDD1599  [3]
 LDCM0396  CL125 HEK-293T C879(1.23); C287(1.15)  LDD1600  [3]
 LDCM0397  CL126 HEK-293T C903(0.88)  LDD1601  [3]
 LDCM0398  CL127 HEK-293T C903(1.00)  LDD1602  [3]
 LDCM0399  CL128 HEK-293T C287(1.16)  LDD1603  [3]
 LDCM0400  CL13 HEK-293T C879(1.21); C287(1.07)  LDD1604  [3]
 LDCM0401  CL14 HEK-293T C903(0.95)  LDD1605  [3]
 LDCM0402  CL15 HEK-293T C903(1.06)  LDD1606  [3]
 LDCM0403  CL16 HEK-293T C287(1.17)  LDD1607  [3]
 LDCM0404  CL17 HEK-293T C655(1.15); C287(1.78)  LDD1608  [3]
 LDCM0406  CL19 HEK-293T C655(0.64); C287(1.19); C903(1.10)  LDD1610  [3]
 LDCM0407  CL2 HEK-293T C903(0.82)  LDD1611  [3]
 LDCM0408  CL20 HEK-293T C655(1.08); C287(1.30); C903(1.18)  LDD1612  [3]
 LDCM0409  CL21 HEK-293T C287(1.74)  LDD1613  [3]
 LDCM0410  CL22 HEK-293T C655(1.25); C287(1.15); C903(1.08)  LDD1614  [3]
 LDCM0411  CL23 HEK-293T C655(0.77); C287(1.14); C903(1.11); C889(0.82)  LDD1615  [3]
 LDCM0412  CL24 HEK-293T C287(1.70); C82(1.00); C1061(0.92)  LDD1616  [3]
 LDCM0413  CL25 HEK-293T C879(1.23); C287(1.31)  LDD1617  [3]
 LDCM0414  CL26 HEK-293T C903(1.01)  LDD1618  [3]
 LDCM0415  CL27 HEK-293T C903(1.01)  LDD1619  [3]
 LDCM0416  CL28 HEK-293T C287(1.45)  LDD1620  [3]
 LDCM0417  CL29 HEK-293T C655(0.98); C287(1.06)  LDD1621  [3]
 LDCM0418  CL3 HEK-293T C903(1.07)  LDD1622  [3]
 LDCM0420  CL31 HEK-293T C655(0.78); C287(1.12); C903(1.05)  LDD1624  [3]
 LDCM0421  CL32 HEK-293T C655(1.78); C287(1.10); C903(1.09)  LDD1625  [3]
 LDCM0422  CL33 HEK-293T C287(1.81)  LDD1626  [3]
 LDCM0423  CL34 HEK-293T C655(1.13); C287(1.41); C903(1.06)  LDD1627  [3]
 LDCM0424  CL35 HEK-293T C655(0.74); C287(1.26); C903(0.87); C889(0.86)  LDD1628  [3]
 LDCM0425  CL36 HEK-293T C287(1.49); C82(1.08); C1061(0.85)  LDD1629  [3]
 LDCM0426  CL37 HEK-293T C879(1.07); C287(1.08)  LDD1630  [3]
 LDCM0428  CL39 HEK-293T C903(0.86)  LDD1632  [3]
 LDCM0429  CL4 HEK-293T C287(0.55)  LDD1633  [3]
 LDCM0430  CL40 HEK-293T C287(1.07)  LDD1634  [3]
 LDCM0431  CL41 HEK-293T C655(1.41); C287(1.20)  LDD1635  [3]
 LDCM0433  CL43 HEK-293T C655(0.71); C287(0.89); C903(0.95)  LDD1637  [3]
 LDCM0434  CL44 HEK-293T C655(1.58); C287(1.26); C903(0.98)  LDD1638  [3]
 LDCM0435  CL45 HEK-293T C287(1.48)  LDD1639  [3]
 LDCM0436  CL46 HEK-293T C655(1.00); C287(1.37); C903(1.03)  LDD1640  [3]
 LDCM0437  CL47 HEK-293T C655(0.84); C287(1.31); C903(0.90); C889(0.86)  LDD1641  [3]
 LDCM0438  CL48 HEK-293T C287(1.48); C82(1.25); C1061(1.08)  LDD1642  [3]
 LDCM0439  CL49 HEK-293T C879(1.17); C287(0.99)  LDD1643  [3]
 LDCM0440  CL5 HEK-293T C655(1.51); C287(1.10)  LDD1644  [3]
 LDCM0441  CL50 HEK-293T C903(0.80)  LDD1645  [3]
 LDCM0443  CL52 HEK-293T C287(1.13)  LDD1646  [3]
 LDCM0444  CL53 HEK-293T C655(1.37); C287(1.44)  LDD1647  [3]
 LDCM0446  CL55 HEK-293T C655(0.71); C287(1.22); C903(1.12)  LDD1649  [3]
 LDCM0447  CL56 HEK-293T C655(1.24); C287(1.24); C903(1.09)  LDD1650  [3]
 LDCM0448  CL57 HEK-293T C287(1.71)  LDD1651  [3]
 LDCM0449  CL58 HEK-293T C655(1.39); C287(1.18); C903(1.09)  LDD1652  [3]
 LDCM0450  CL59 HEK-293T C655(0.96); C287(1.26); C903(0.95); C889(0.85)  LDD1653  [3]
 LDCM0452  CL60 HEK-293T C287(1.47); C82(1.04); C1061(0.91)  LDD1655  [3]
 LDCM0453  CL61 HEK-293T C879(1.16); C287(0.98)  LDD1656  [3]
 LDCM0454  CL62 HEK-293T C903(0.90)  LDD1657  [3]
 LDCM0455  CL63 HEK-293T C903(1.07)  LDD1658  [3]
 LDCM0456  CL64 HEK-293T C287(1.47)  LDD1659  [3]
 LDCM0457  CL65 HEK-293T C655(1.40); C287(1.05)  LDD1660  [3]
 LDCM0459  CL67 HEK-293T C655(0.61); C287(1.40); C903(0.93)  LDD1662  [3]
 LDCM0460  CL68 HEK-293T C655(1.17); C287(1.21); C903(1.04)  LDD1663  [3]
 LDCM0461  CL69 HEK-293T C287(1.40)  LDD1664  [3]
 LDCM0462  CL7 HEK-293T C655(0.86); C287(0.95); C903(1.17)  LDD1665  [3]
 LDCM0463  CL70 HEK-293T C655(1.11); C287(1.07); C903(1.13)  LDD1666  [3]
 LDCM0464  CL71 HEK-293T C655(0.63); C287(1.23); C903(1.11); C889(0.90)  LDD1667  [3]
 LDCM0465  CL72 HEK-293T C287(1.36); C82(0.82); C1061(0.89)  LDD1668  [3]
 LDCM0466  CL73 HEK-293T C879(1.09); C287(1.15)  LDD1669  [3]
 LDCM0467  CL74 HEK-293T C903(0.94)  LDD1670  [3]
 LDCM0469  CL76 HEK-293T C287(1.12)  LDD1672  [3]
 LDCM0470  CL77 HEK-293T C655(1.43); C287(1.35)  LDD1673  [3]
 LDCM0472  CL79 HEK-293T C655(0.87); C287(0.76); C903(0.91)  LDD1675  [3]
 LDCM0473  CL8 HEK-293T C655(1.02); C287(1.70); C903(1.02)  LDD1676  [3]
 LDCM0474  CL80 HEK-293T C655(1.34); C287(1.18); C903(1.06)  LDD1677  [3]
 LDCM0475  CL81 HEK-293T C287(1.19)  LDD1678  [3]
 LDCM0476  CL82 HEK-293T C655(1.03); C287(1.09); C903(1.14)  LDD1679  [3]
 LDCM0477  CL83 HEK-293T C655(0.86); C287(1.09); C903(0.87); C889(0.91)  LDD1680  [3]
 LDCM0478  CL84 HEK-293T C287(1.62); C82(1.10); C1061(1.05)  LDD1681  [3]
 LDCM0479  CL85 HEK-293T C879(1.10); C287(1.07)  LDD1682  [3]
 LDCM0480  CL86 HEK-293T C903(0.81)  LDD1683  [3]
 LDCM0481  CL87 HEK-293T C903(0.84)  LDD1684  [3]
 LDCM0482  CL88 HEK-293T C287(1.10)  LDD1685  [3]
 LDCM0483  CL89 HEK-293T C655(1.32); C287(1.05)  LDD1686  [3]
 LDCM0484  CL9 HEK-293T C287(1.34)  LDD1687  [3]
 LDCM0486  CL91 HEK-293T C655(0.68); C287(1.00); C903(1.04)  LDD1689  [3]
 LDCM0487  CL92 HEK-293T C655(1.00); C287(1.13); C903(1.03)  LDD1690  [3]
 LDCM0488  CL93 HEK-293T C287(1.49)  LDD1691  [3]
 LDCM0489  CL94 HEK-293T C655(1.26); C287(1.09); C903(1.02)  LDD1692  [3]
 LDCM0490  CL95 HEK-293T C655(0.88); C287(1.48); C903(1.02); C889(1.46)  LDD1693  [3]
 LDCM0491  CL96 HEK-293T C287(1.55); C82(1.07); C1061(1.33)  LDD1694  [3]
 LDCM0492  CL97 HEK-293T C879(1.14); C287(1.21)  LDD1695  [3]
 LDCM0493  CL98 HEK-293T C903(0.91)  LDD1696  [3]
 LDCM0494  CL99 HEK-293T C903(1.06)  LDD1697  [3]
 LDCM0495  E2913 HEK-293T C903(0.64)  LDD1698  [3]
 LDCM0468  Fragment33 HEK-293T C903(1.05)  LDD1671  [3]
 LDCM0427  Fragment51 HEK-293T C903(0.88)  LDD1631  [3]
 LDCM0022  KB02 AU565 C90(2.15)  LDD2265  [1]
 LDCM0023  KB03 AU565 C90(2.01)  LDD2682  [1]
 LDCM0024  KB05 OAW-28 C90(1.99)  LDD3368  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Sortilin (SORT1) VPS10-related sortilin family Q99523
Cytokine and receptor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Ciliary neurotrophic factor (CNTF) CNTF family P26441

The Drug(s) Related To This Target

Phase 2
Click To Hide/Show 1 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Emfilermin . D0L1FN

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
2 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
3 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402