Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C319  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 7 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP15422  Prostaglandin reductase 3 (PTGR3) 10.2
 LDTP12013  dCTP pyrophosphatase 1 (DCTPP1) 9.4
 LDTP09799  DCN1-like protein 4 (DCUN1D4) 6.5
 LDTP04211  Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) 6.5
 LDTP10032  7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) 6.4
 LDTP05396  Histone-lysine N-methyltransferase 2A (KMT2A) 5.1
 LDTP01333  Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) 4.9
Other
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP01075  Protein CutA (CUTA) 14.3
 LDTP09297  Large ribosomal subunit protein mL64 (GADD45GIP1) 6.2

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587