Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C152  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP01328  CAAX prenyl protease 1 homolog (ZMPSTE24) 21.1
 LDTP02254  ATP-dependent translocase ABCB1 (ABCB1) 9.6
 LDTP07831  Transmembrane protein with metallophosphoesterase domain (TMPPE) 8.3
Transporter and channel
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP00262  Acetyl-coenzyme A transporter 1 (SLC33A1) 13.4
 LDTP10958  Sigma non-opioid intracellular receptor 1 (SIGMAR1) 7.4
 LDTP06945  Sigma intracellular receptor 2 (TMEM97) 5.7

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587