General Information of Experiment

Probe Name C132  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 6 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP12013  dCTP pyrophosphatase 1 (DCTPP1) 30.3
 LDTP15422  Prostaglandin reductase 3 (PTGR3) 17.6
 LDTP04211  Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) 12.6
 LDTP01333  Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) 9.1
 LDTP12628  Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) 8.2
 LDTP04051  Nicotinamide phosphoribosyltransferase (NAMPT) 5.4
Transporter and channel
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP00865  Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) 6.4
Other
Click to Show/Hide to Show 5 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP14486  Clustered mitochondria protein homolog (CLUH) 11.6
 LDTP15623  Neuferricin (CYB5D2) 6.4
 LDTP13755  Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) 6.1
 LDTP01075  Protein CutA (CUTA) 5.0
 LDTP08689  Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) 4.9

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587