Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name EN  Probe Info 
Probe concentration 5 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
SILAC
Competitor Name Entinostat  Competitor Info 
Competitor Concentration 50 uM
In Vivo Experiment Model Model Type Cell lysate
Derived Tissue Liver
Disease Model Hepatoblastoma [ICD-11:DB91]
Model Name Human hepatoblastoma cell lysate (Hep-G2)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 6 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP05676  Chromodomain-helicase-DNA-binding protein 3 (CHD3) 3.3
 LDTP12586  Phenylalanine--tRNA ligase beta subunit (FARSB) 2.1
 LDTP05950  Cullin-4B (CUL4B) 2.0
 LDTP04689  Adenosine kinase (ADK) 1.8
 LDTP02548  Uridine 5'-monophosphate synthase (UMPS) 1.6
 LDTP04273  DNA primase large subunit (PRIM2) 1.5
Transporter and channel
Click to Show/Hide to Show 4 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP12090  Sideroflexin-1 (SFXN1) 2.2
 LDTP03664  Kinesin-1 heavy chain (KIF5B) 1.6
 LDTP00810  Exportin-T (XPOT) 1.6
 LDTP02612  Nucleoprotein TPR (TPR) 1.5
Transcription factor
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP09932  SWI/SNF complex subunit SMARCC1 (SMARCC1) 1.6
Other
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03719  Serpin B6 (SERPINB6) 2.5
 LDTP01021  Perilipin-3 (PLIN3) 1.7
 LDTP08922  Cleavage and polyadenylation specificity factor subunit 7 (CPSF7) 1.5

References

1 Expanding the "minimalist" small molecule tagging approach to different bioactive compounds. Org Biomol Chem. 2019 Mar 13;17(11):3010-3017. doi: 10.1039/c8ob03175d.