Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name	Kambe_26			Probe Info
Probe concentration	10 uM
Criteria	Quantification: Probe vs (Probe+Competitor)
Quantitative Method	SILAC
Competitor Name	kambe_cp70			Competitor Info
Competitor Concentration	20 uM
*In Vivo* Experiment Model**	Model Type		Living cell
	Derived Tissue		Prostate
	Disease Model	Prostate carcinoma [ICD-11:2C82]
	Model Name	Human prostate carcinoma cells (PC-3)

Interaction Altas of This Experiment [1]

Enzyme

Click to Show/Hide to Show 4 Protein Related to This Bioclass

Target ID	Target Name	Binding Ratio
LDTP08979	Prostaglandin reductase 2 (PTGR2)	4.9
LDTP03912	Trifunctional enzyme subunit alpha, mitochondrial (HADHA)	2.7
LDTP03223	Small ribosomal subunit protein uS3 (RPS3)	2.1
LDTP12163	Calcyclin-binding protein (CACYBP)	2.0

Transporter and channel

Click to Show/Hide to Show 1 Protein Related to This Bioclass

Target ID	Target Name					Binding Ratio
LDTP04071	Voltage-dependent anion-selective channel protein 2 (VDAC2)					2.1

Other

Click to Show/Hide to Show 3 Protein Related to This Bioclass

Target ID	Target Name	Binding Ratio
LDTP01316	Breast cancer anti-estrogen resistance protein 3 (BCAR3)	20.0
LDTP13630	Neudesin (NENF)	2.1
LDTP09851	Protein TFG (TFG)	2.0

References

1	Mapping the protein interaction landscape for fully functionalized small-molecule probes in human cells. J Am Chem Soc. 2014 Jul 30;136(30):10777-82. doi: 10.1021/ja505517t. Epub 2014 Jul 21.