Details of the Target

General Information of Target

Target ID LDTP09784
Target Name Phosphatidate phosphatase LPIN2 (LPIN2)
Gene Name LPIN2
Gene ID 9663
Synonyms
KIAA0249; Phosphatidate phosphatase LPIN2; EC 3.1.3.4; Lipin-2
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MVDKNIYIIQGEINIVVGAIKRNARWSTHTPLDEERDPLLHSFGHLKEVLNSITELSEIE
PNVFLRPFLEVIRSEDTTGPITGLALTSVNKFLSYALIDPTHEGTAEGMENMADAVTHAR
FVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKS
AEHTLVDMVQLLFTRLPQFKEEPKNYVGTNMKKLKMRAGGMSDSSKWKKQKRSPRPPRHM
TKVTPGSELPTPNGTTLSSNLTGGMPFIDVPTPISSASSEAASAVVSPSTDSGLEFSSQT
TSKEDLTDLEQPGSPGYSTATEPGSSELGVPEQPDLQQEGTHVEKSQSASVESIPEVLEE
CTSPADHSDSASVHDMDYVNPRGVRFTQSSQKEGTALVPYGLPCIRELFRFLISLTNPHD
RHNSEVMIHMGLHLLTVALESAPVAQCQTLLGLIKDEMCRHLFQLLSIERLNLYAASLRV
CFLLFESMREHLKFQMEMYIKKLMEIITVENPKMPYEMKEMALEAIVQLWRIPSFVTELY
INYDCDYYCSNLFEELTKLLSKNAFPVSGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNS
LTQQEKKETARPSCEIVDGTREASNTERTASDGKAVGMASDIPGLHLPGGGRLPPEHGKS
GCSDLEEAVDSGADKKFARKPPRFSCLLPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQ
FLQEKGLLTIPMDNTEVAQWLRENPRLDKKMIGEFVSDRKNIDLLESFVSTFSFQGLRLD
EALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGSPFANSDACFSLAYAVIMLNTDQHN
HNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTGLVRENYV
WNVLLHRGATPEGIFLRVPTASYDLDLFTMTWGPTIAALSYVFDKSLEETIIQKAISGFR
KCAMISAHYGLSDVFDNLIISLCKFTALSSESIENLPSVFGSNPKAHIAAKTVFHLAHRH
GDILREGWKNIMEAMLQLFRAQLLPKAMIEVEDFVDPNGKISLQREETPSNRGESTVLSF
VSWLTLSGPEQSSVRGPSTENQEAKRVALECIKQCDPEKMITESKFLQLESLQELMKALV
SVTPDEETYDEEDAAFCLEMLLRIVLENRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERA
VVGLLRLAIRLLRREEISAQVLLSLRILLLMKPSVLSRVSHQVAYGLHELLKTNAANIHS
GDDWATLFTLLECIGSGVKPPAALQATARADAPDAGAQSDSELPSYHQNDVSLDRGYTSD
SEVYTDHGRPGKIHRSATDADVVNSGWLVVGKDDVDNSKPGPSRPGPSPLINQYSLTVGL
DLGPHDTKSLLKCVESLSFIVRDAAHITPDNFELCVKTLRIFVEASLNGGCKSQEKRGKS
HKYDSKGNRFKKKSKEGSMLRRPRTSSQHASRGGQSDDDEDEGVPASYHTVSLQVSQDLL
DLMHTLHTRAASIYSSWAEEQRHLETGGQKIEADSRTLWAHCWCPLLQGIACLCCDARRQ
VRMQALTYLQRALLVHDLQKLDALEWESCFNKVLFPLLTKLLENISPADVGGMEETRMRA
STLLSKVFLQHLSPLLSLSTFAALWLTILDFMDKYMHAGSSDLLSEAIPESLKNMLLVMD
TAEIFHSADARGGGPSALWEITWERIDCFLPHLRDELFKQTVIQDPMPMEPQGQKPLASA
HLTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSPTPDG
PPPLAQPPLILQPLASPLQVGVPPMTLPIILNPALIEATSPVPLLATPRPTDPIPTSEVN
Target Bioclass
Enzyme
Family
Lipin family
Subcellular location
Nucleus
Function
Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Plays important roles in controlling the metabolism of fatty acids at different levels. Acts also as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism.
Uniprot ID
Q92539
Ensemble ID
ENST00000261596.9
HGNC ID
HGNC:14450

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
DBIA
 Probe Info  		C874(1.22); C881(1.22)  LDD0078  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C733(1.36)  LDD0812  [2]
 LDCM0215  AC10 PaTu 8988t C672(0.73)  LDD1094  [2]
 LDCM0216  AC100 PaTu 8988t C874(0.84); C881(1.44)  LDD1095  [2]
 LDCM0217  AC101 PaTu 8988t C874(0.84); C881(1.52)  LDD1096  [2]
 LDCM0218  AC102 PaTu 8988t C874(0.87); C881(1.36)  LDD1097  [2]
 LDCM0219  AC103 PaTu 8988t C874(1.29); C881(1.39)  LDD1098  [2]
 LDCM0220  AC104 PaTu 8988t C874(0.93); C881(1.05)  LDD1099  [2]
 LDCM0221  AC105 PaTu 8988t C874(0.70); C881(0.99)  LDD1100  [2]
 LDCM0222  AC106 PaTu 8988t C874(1.03); C881(1.02)  LDD1101  [2]
 LDCM0223  AC107 PaTu 8988t C874(1.25); C881(1.44)  LDD1102  [2]
 LDCM0224  AC108 PaTu 8988t C874(1.41); C881(1.41)  LDD1103  [2]
 LDCM0225  AC109 PaTu 8988t C874(1.14); C881(1.36)  LDD1104  [2]
 LDCM0226  AC11 PaTu 8988t C672(0.88)  LDD1105  [2]
 LDCM0227  AC110 PaTu 8988t C874(1.52); C881(2.33)  LDD1106  [2]
 LDCM0228  AC111 PaTu 8988t C874(1.32); C881(1.46)  LDD1107  [2]
 LDCM0229  AC112 PaTu 8988t C874(1.11); C881(1.64)  LDD1108  [2]
 LDCM0230  AC113 HEK-293T C881(0.97)  LDD0828  [2]
 LDCM0231  AC114 HEK-293T C881(0.90)  LDD0829  [2]
 LDCM0232  AC115 HEK-293T C881(0.78)  LDD0830  [2]
 LDCM0233  AC116 HEK-293T C881(0.88)  LDD0831  [2]
 LDCM0234  AC117 HEK-293T C881(1.35)  LDD0832  [2]
 LDCM0235  AC118 HEK-293T C881(1.02)  LDD0833  [2]
 LDCM0236  AC119 HEK-293T C881(1.08)  LDD0834  [2]
 LDCM0237  AC12 PaTu 8988t C672(0.83)  LDD1116  [2]
 LDCM0238  AC120 HEK-293T C881(1.24)  LDD0836  [2]
 LDCM0239  AC121 HEK-293T C881(1.14)  LDD0837  [2]
 LDCM0240  AC122 HEK-293T C881(1.51)  LDD0838  [2]
 LDCM0241  AC123 HEK-293T C881(1.28)  LDD0839  [2]
 LDCM0242  AC124 HEK-293T C881(1.42)  LDD0840  [2]
 LDCM0243  AC125 HEK-293T C881(1.03)  LDD0841  [2]
 LDCM0244  AC126 HEK-293T C881(1.32)  LDD0842  [2]
 LDCM0245  AC127 HEK-293T C881(1.19)  LDD0843  [2]
 LDCM0246  AC128 HEK-293T C733(1.17)  LDD0844  [2]
 LDCM0247  AC129 HEK-293T C733(1.31)  LDD0845  [2]
 LDCM0249  AC130 HEK-293T C733(1.33)  LDD0847  [2]
 LDCM0250  AC131 HEK-293T C733(1.37)  LDD0848  [2]
 LDCM0251  AC132 HEK-293T C733(1.25)  LDD0849  [2]
 LDCM0252  AC133 HEK-293T C733(1.18)  LDD0850  [2]
 LDCM0253  AC134 HEK-293T C733(1.38)  LDD0851  [2]
 LDCM0254  AC135 HEK-293T C733(1.30)  LDD0852  [2]
 LDCM0255  AC136 HEK-293T C733(1.16)  LDD0853  [2]
 LDCM0256  AC137 HEK-293T C733(1.21)  LDD0854  [2]
 LDCM0257  AC138 HEK-293T C733(1.40)  LDD0855  [2]
 LDCM0258  AC139 HEK-293T C733(1.30)  LDD0856  [2]
 LDCM0259  AC14 PaTu 8988t C672(1.05)  LDD1138  [2]
 LDCM0260  AC140 HEK-293T C733(1.20)  LDD0858  [2]
 LDCM0261  AC141 HEK-293T C733(1.12)  LDD0859  [2]
 LDCM0262  AC142 HEK-293T C733(1.23)  LDD0860  [2]
 LDCM0270  AC15 PaTu 8988t C672(0.77)  LDD1149  [2]
 LDCM0276  AC17 PaTu 8988t C672(0.80)  LDD1155  [2]
 LDCM0277  AC18 PaTu 8988t C672(0.77)  LDD1156  [2]
 LDCM0278  AC19 PaTu 8988t C672(1.09)  LDD1157  [2]
 LDCM0279  AC2 HEK-293T C733(1.13)  LDD0877  [2]
 LDCM0280  AC20 PaTu 8988t C672(0.74)  LDD1159  [2]
 LDCM0281  AC21 PaTu 8988t C672(0.84)  LDD1160  [2]
 LDCM0282  AC22 PaTu 8988t C672(0.88)  LDD1161  [2]
 LDCM0283  AC23 PaTu 8988t C672(0.74)  LDD1162  [2]
 LDCM0284  AC24 PaTu 8988t C672(0.60)  LDD1163  [2]
 LDCM0285  AC25 HEK-293T C733(1.20)  LDD0883  [2]
 LDCM0286  AC26 HEK-293T C733(1.32)  LDD0884  [2]
 LDCM0287  AC27 HEK-293T C733(1.16)  LDD0885  [2]
 LDCM0288  AC28 HEK-293T C733(1.22)  LDD0886  [2]
 LDCM0289  AC29 HEK-293T C733(1.10)  LDD0887  [2]
 LDCM0290  AC3 HEK-293T C733(0.98)  LDD0888  [2]
 LDCM0291  AC30 HEK-293T C733(1.42)  LDD0889  [2]
 LDCM0292  AC31 HEK-293T C733(1.26)  LDD0890  [2]
 LDCM0293  AC32 HEK-293T C733(1.03)  LDD0891  [2]
 LDCM0294  AC33 HEK-293T C733(1.20)  LDD0892  [2]
 LDCM0295  AC34 HEK-293T C733(1.26)  LDD0893  [2]
 LDCM0296  AC35 PaTu 8988t C672(0.85)  LDD1175  [2]
 LDCM0297  AC36 PaTu 8988t C672(0.85)  LDD1176  [2]
 LDCM0298  AC37 PaTu 8988t C672(0.86)  LDD1177  [2]
 LDCM0299  AC38 PaTu 8988t C672(0.84)  LDD1178  [2]
 LDCM0300  AC39 PaTu 8988t C672(0.83)  LDD1179  [2]
 LDCM0301  AC4 HEK-293T C733(1.10)  LDD0899  [2]
 LDCM0302  AC40 PaTu 8988t C672(0.79)  LDD1181  [2]
 LDCM0303  AC41 PaTu 8988t C672(0.85)  LDD1182  [2]
 LDCM0304  AC42 PaTu 8988t C672(0.92)  LDD1183  [2]
 LDCM0305  AC43 PaTu 8988t C672(0.87)  LDD1184  [2]
 LDCM0306  AC44 PaTu 8988t C672(0.89)  LDD1185  [2]
 LDCM0307  AC45 PaTu 8988t C672(0.90)  LDD1186  [2]
 LDCM0308  AC46 HEK-293T C733(1.06); C322(1.10)  LDD1547  [3]
 LDCM0311  AC49 HEK-293T C790(1.02)  LDD1550  [3]
 LDCM0312  AC5 HEK-293T C733(1.16)  LDD0910  [2]
 LDCM0313  AC50 HEK-293T C733(0.99)  LDD1552  [3]
 LDCM0317  AC54 HEK-293T C733(1.07); C322(1.11)  LDD1556  [3]
 LDCM0320  AC57 HEK-293T C790(0.91)  LDD1559  [3]
 LDCM0321  AC58 HEK-293T C733(1.27)  LDD1560  [3]
 LDCM0323  AC6 PaTu 8988t C672(0.94)  LDD1202  [2]
 LDCM0326  AC62 HEK-293T C733(1.24); C322(1.12)  LDD1565  [3]
 LDCM0332  AC68 HEK-293T C881(1.39)  LDD0930  [2]
 LDCM0333  AC69 HEK-293T C881(1.03)  LDD0931  [2]
 LDCM0334  AC7 PaTu 8988t C672(1.06)  LDD1213  [2]
 LDCM0335  AC70 HEK-293T C881(0.78)  LDD0933  [2]
 LDCM0336  AC71 HEK-293T C881(0.94)  LDD0934  [2]
 LDCM0337  AC72 HEK-293T C881(1.07)  LDD0935  [2]
 LDCM0338  AC73 HEK-293T C881(0.75)  LDD0936  [2]
 LDCM0339  AC74 HEK-293T C881(0.87)  LDD0937  [2]
 LDCM0340  AC75 HEK-293T C881(0.78)  LDD0938  [2]
 LDCM0341  AC76 HEK-293T C881(1.19)  LDD0939  [2]
 LDCM0342  AC77 HEK-293T C881(0.91)  LDD0940  [2]
 LDCM0343  AC78 HEK-293T C881(1.34)  LDD0941  [2]
 LDCM0344  AC79 HEK-293T C881(1.41)  LDD0942  [2]
 LDCM0345  AC8 PaTu 8988t C672(0.95)  LDD1224  [2]
 LDCM0346  AC80 HEK-293T C881(1.13)  LDD0944  [2]
 LDCM0347  AC81 HEK-293T C881(1.56)  LDD0945  [2]
 LDCM0348  AC82 HEK-293T C881(0.92)  LDD0946  [2]
 LDCM0349  AC83 HEK-293T C733(0.95)  LDD0947  [2]
 LDCM0350  AC84 HEK-293T C733(0.91)  LDD0948  [2]
 LDCM0351  AC85 HEK-293T C733(0.99)  LDD0949  [2]
 LDCM0352  AC86 HEK-293T C733(0.87)  LDD0950  [2]
 LDCM0353  AC87 HEK-293T C733(0.87)  LDD0951  [2]
 LDCM0354  AC88 HEK-293T C733(0.93)  LDD0952  [2]
 LDCM0355  AC89 HEK-293T C733(0.81)  LDD0953  [2]
 LDCM0357  AC90 HEK-293T C733(0.91)  LDD0955  [2]
 LDCM0358  AC91 HEK-293T C733(0.97)  LDD0956  [2]
 LDCM0359  AC92 HEK-293T C733(1.05)  LDD0957  [2]
 LDCM0360  AC93 HEK-293T C733(0.97)  LDD0958  [2]
 LDCM0361  AC94 HEK-293T C733(0.93)  LDD0959  [2]
 LDCM0362  AC95 HEK-293T C733(1.09)  LDD0960  [2]
 LDCM0363  AC96 HEK-293T C733(0.93)  LDD0961  [2]
 LDCM0364  AC97 HEK-293T C733(0.99)  LDD0962  [2]
 LDCM0365  AC98 PaTu 8988t C874(0.75); C881(1.26)  LDD1244  [2]
 LDCM0366  AC99 PaTu 8988t C874(1.24); C881(1.12)  LDD1245  [2]
 LDCM0248  AKOS034007472 PaTu 8988t C672(0.93)  LDD1127  [2]
 LDCM0356  AKOS034007680 PaTu 8988t C672(0.88)  LDD1235  [2]
 LDCM0275  AKOS034007705 PaTu 8988t C672(0.80)  LDD1154  [2]
 LDCM0020  ARS-1620 HCC44 C874(1.22); C881(1.22)  LDD0078  [2]
 LDCM0367  CL1 PaTu 8988t C874(0.96); C881(0.96)  LDD1246  [2]
 LDCM0368  CL10 PaTu 8988t C874(0.80); C881(0.80)  LDD1247  [2]
 LDCM0369  CL100 HEK-293T C733(1.03)  LDD0967  [2]
 LDCM0370  CL101 PaTu 8988t C672(0.95)  LDD1249  [2]
 LDCM0371  CL102 PaTu 8988t C672(0.93)  LDD1250  [2]
 LDCM0372  CL103 PaTu 8988t C672(0.95)  LDD1251  [2]
 LDCM0373  CL104 PaTu 8988t C672(0.99)  LDD1252  [2]
 LDCM0374  CL105 PaTu 8988t C672(0.78)  LDD1253  [2]
 LDCM0375  CL106 PaTu 8988t C672(0.83)  LDD1254  [2]
 LDCM0376  CL107 PaTu 8988t C672(0.78)  LDD1255  [2]
 LDCM0377  CL108 PaTu 8988t C672(0.84)  LDD1256  [2]
 LDCM0378  CL109 PaTu 8988t C672(0.88)  LDD1257  [2]
 LDCM0379  CL11 PaTu 8988t C874(0.68); C881(0.68)  LDD1258  [2]
 LDCM0380  CL110 PaTu 8988t C672(0.75)  LDD1259  [2]
 LDCM0381  CL111 PaTu 8988t C672(0.76)  LDD1260  [2]
 LDCM0382  CL112 HEK-293T C733(1.18)  LDD0980  [2]
 LDCM0383  CL113 HEK-293T C733(1.15)  LDD0981  [2]
 LDCM0384  CL114 HEK-293T C733(1.07)  LDD0982  [2]
 LDCM0385  CL115 HEK-293T C733(1.14)  LDD0983  [2]
 LDCM0386  CL116 HEK-293T C733(1.57)  LDD0984  [2]
 LDCM0387  CL117 PaTu 8988t C672(0.84)  LDD1266  [2]
 LDCM0388  CL118 PaTu 8988t C672(0.90)  LDD1267  [2]
 LDCM0389  CL119 PaTu 8988t C672(0.82)  LDD1268  [2]
 LDCM0390  CL12 PaTu 8988t C874(1.25); C881(1.25)  LDD1269  [2]
 LDCM0391  CL120 PaTu 8988t C672(0.83)  LDD1270  [2]
 LDCM0392  CL121 HEK-293T C733(0.93); C790(0.99)  LDD1596  [3]
 LDCM0393  CL122 HEK-293T C733(0.90); C790(1.08)  LDD1597  [3]
 LDCM0396  CL125 HEK-293T C733(1.11); C790(0.96)  LDD1600  [3]
 LDCM0397  CL126 HEK-293T C733(1.05); C790(1.07)  LDD1601  [3]
 LDCM0400  CL13 PaTu 8988t C874(0.87); C881(0.87)  LDD1279  [2]
 LDCM0401  CL14 PaTu 8988t C874(1.81); C881(1.81)  LDD1280  [2]
 LDCM0402  CL15 PaTu 8988t C874(1.34); C881(1.34)  LDD1281  [2]
 LDCM0403  CL16 HEK-293T C881(0.93)  LDD1001  [2]
 LDCM0404  CL17 HEK-293T C881(0.96)  LDD1002  [2]
 LDCM0405  CL18 HEK-293T C881(0.89)  LDD1003  [2]
 LDCM0406  CL19 HEK-293T C881(1.03)  LDD1004  [2]
 LDCM0407  CL2 PaTu 8988t C874(1.08); C881(1.08)  LDD1286  [2]
 LDCM0408  CL20 HEK-293T C881(1.14)  LDD1006  [2]
 LDCM0409  CL21 HEK-293T C881(1.32)  LDD1007  [2]
 LDCM0410  CL22 HEK-293T C881(1.18)  LDD1008  [2]
 LDCM0411  CL23 HEK-293T C881(1.02)  LDD1009  [2]
 LDCM0412  CL24 HEK-293T C881(1.50)  LDD1010  [2]
 LDCM0413  CL25 HEK-293T C881(1.07)  LDD1011  [2]
 LDCM0414  CL26 HEK-293T C881(1.05)  LDD1012  [2]
 LDCM0415  CL27 HEK-293T C881(0.97)  LDD1013  [2]
 LDCM0416  CL28 HEK-293T C881(1.11)  LDD1014  [2]
 LDCM0417  CL29 HEK-293T C881(1.27)  LDD1015  [2]
 LDCM0418  CL3 PaTu 8988t C874(0.69); C881(0.69)  LDD1297  [2]
 LDCM0419  CL30 HEK-293T C881(1.15)  LDD1017  [2]
 LDCM0420  CL31 PaTu 8988t C874(0.59); C881(0.59)  LDD1299  [2]
 LDCM0421  CL32 PaTu 8988t C874(0.43); C881(0.43)  LDD1300  [2]
 LDCM0422  CL33 PaTu 8988t C874(0.79); C881(0.79)  LDD1301  [2]
 LDCM0423  CL34 PaTu 8988t C874(0.50); C881(0.50)  LDD1302  [2]
 LDCM0424  CL35 PaTu 8988t C874(0.67); C881(0.67)  LDD1303  [2]
 LDCM0425  CL36 PaTu 8988t C874(0.66); C881(0.66)  LDD1304  [2]
 LDCM0426  CL37 PaTu 8988t C874(0.38); C881(0.38)  LDD1305  [2]
 LDCM0428  CL39 PaTu 8988t C874(0.55); C881(0.55)  LDD1307  [2]
 LDCM0429  CL4 PaTu 8988t C874(0.84); C881(0.84)  LDD1308  [2]
 LDCM0430  CL40 PaTu 8988t C874(0.86); C881(0.86)  LDD1309  [2]
 LDCM0431  CL41 PaTu 8988t C874(0.55); C881(0.55)  LDD1310  [2]
 LDCM0432  CL42 PaTu 8988t C874(0.64); C881(0.64)  LDD1311  [2]
 LDCM0433  CL43 PaTu 8988t C874(0.47); C881(0.47)  LDD1312  [2]
 LDCM0434  CL44 PaTu 8988t C874(0.49); C881(0.49)  LDD1313  [2]
 LDCM0435  CL45 PaTu 8988t C874(0.65); C881(0.65)  LDD1314  [2]
 LDCM0436  CL46 HEK-293T C733(1.10); C322(0.61)  LDD1640  [3]
 LDCM0439  CL49 HEK-293T C733(1.13); C790(1.12)  LDD1643  [3]
 LDCM0440  CL5 PaTu 8988t C874(0.92); C881(0.92)  LDD1319  [2]
 LDCM0441  CL50 HEK-293T C733(0.81); C790(1.19)  LDD1645  [3]
 LDCM0444  CL53 HEK-293T C790(1.06)  LDD1647  [3]
 LDCM0445  CL54 HEK-293T C733(1.35)  LDD1648  [3]
 LDCM0449  CL58 HEK-293T C733(1.71); C322(0.69)  LDD1652  [3]
 LDCM0451  CL6 PaTu 8988t C874(1.42); C881(1.42)  LDD1330  [2]
 LDCM0453  CL61 HEK-293T C881(0.58)  LDD1051  [2]
 LDCM0454  CL62 HEK-293T C881(0.68)  LDD1052  [2]
 LDCM0455  CL63 HEK-293T C881(0.71)  LDD1053  [2]
 LDCM0456  CL64 HEK-293T C881(0.56)  LDD1054  [2]
 LDCM0457  CL65 HEK-293T C881(0.77)  LDD1055  [2]
 LDCM0458  CL66 HEK-293T C881(0.64)  LDD1056  [2]
 LDCM0459  CL67 HEK-293T C881(0.90)  LDD1057  [2]
 LDCM0460  CL68 HEK-293T C881(0.83)  LDD1058  [2]
 LDCM0461  CL69 HEK-293T C881(0.77)  LDD1059  [2]
 LDCM0462  CL7 PaTu 8988t C874(1.16); C881(1.16)  LDD1341  [2]
 LDCM0463  CL70 HEK-293T C881(0.78)  LDD1061  [2]
 LDCM0464  CL71 HEK-293T C881(0.66)  LDD1062  [2]
 LDCM0465  CL72 HEK-293T C881(0.82)  LDD1063  [2]
 LDCM0466  CL73 HEK-293T C881(0.57)  LDD1064  [2]
 LDCM0467  CL74 HEK-293T C881(0.64)  LDD1065  [2]
 LDCM0469  CL76 PaTu 8988t C672(1.13)  LDD1348  [2]
 LDCM0470  CL77 PaTu 8988t C672(0.89)  LDD1349  [2]
 LDCM0471  CL78 PaTu 8988t C672(1.04)  LDD1350  [2]
 LDCM0472  CL79 PaTu 8988t C672(1.08)  LDD1351  [2]
 LDCM0473  CL8 PaTu 8988t C874(0.68); C881(0.68)  LDD1352  [2]
 LDCM0474  CL80 PaTu 8988t C672(1.02)  LDD1353  [2]
 LDCM0475  CL81 PaTu 8988t C672(0.94)  LDD1354  [2]
 LDCM0476  CL82 PaTu 8988t C672(0.89)  LDD1355  [2]
 LDCM0477  CL83 PaTu 8988t C672(0.93)  LDD1356  [2]
 LDCM0478  CL84 PaTu 8988t C672(1.39)  LDD1357  [2]
 LDCM0479  CL85 PaTu 8988t C672(1.22)  LDD1358  [2]
 LDCM0480  CL86 PaTu 8988t C672(1.12)  LDD1359  [2]
 LDCM0481  CL87 PaTu 8988t C672(0.97)  LDD1360  [2]
 LDCM0482  CL88 PaTu 8988t C672(1.13)  LDD1361  [2]
 LDCM0483  CL89 PaTu 8988t C672(0.98)  LDD1362  [2]
 LDCM0484  CL9 PaTu 8988t C874(1.24); C881(1.24)  LDD1363  [2]
 LDCM0485  CL90 PaTu 8988t C672(0.91)  LDD1364  [2]
 LDCM0486  CL91 HEK-293T C733(1.40)  LDD1084  [2]
 LDCM0487  CL92 HEK-293T C733(0.68)  LDD1085  [2]
 LDCM0488  CL93 HEK-293T C733(1.09)  LDD1086  [2]
 LDCM0489  CL94 HEK-293T C733(0.91)  LDD1087  [2]
 LDCM0490  CL95 HEK-293T C733(0.81)  LDD1088  [2]
 LDCM0491  CL96 HEK-293T C733(1.08)  LDD1089  [2]
 LDCM0492  CL97 HEK-293T C733(1.18)  LDD1090  [2]
 LDCM0493  CL98 HEK-293T C733(0.87)  LDD1091  [2]
 LDCM0494  CL99 HEK-293T C733(0.86)  LDD1092  [2]
 LDCM0468  Fragment33 HEK-293T C881(0.76)  LDD1066  [2]
 LDCM0427  Fragment51 PaTu 8988t C874(0.76); C881(0.76)  LDD1306  [2]
 LDCM0022  KB02 22RV1 C807(2.71)  LDD2243  [4]
 LDCM0023  KB03 22RV1 C807(4.49)  LDD2660  [4]
 LDCM0024  KB05 COLO792 C807(4.09)  LDD3310  [4]
 LDCM0021  THZ1 HCT 116 C874(1.10); C881(1.10)  LDD2173  [2]

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
4 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840