Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C381  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10032  7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) 29.2
 LDTP15422  Prostaglandin reductase 3 (PTGR3) 7.2
 LDTP04211  Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) 4.9
Transporter and channel
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10958  Sigma non-opioid intracellular receptor 1 (SIGMAR1) 6.1
Other
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP01075  Protein CutA (CUTA) 5.9
 LDTP15623  Neuferricin (CYB5D2) 5.8
 LDTP16099  p53 and DNA damage-regulated protein 1 (PDRG1) 5.7

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587