General Information of Experiment

Probe Name Kambe_22  Probe Info 
Probe concentration 10 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
SILAC
Competitor Name kambe_cp71  Competitor Info 
Competitor Concentration 20 uM
In Vivo Experiment Model Model Type Living cell
Derived Tissue Prostate
Disease Model Prostate carcinoma [ICD-11:2C82]
Model Name Human prostate carcinoma cells (PC-3)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 10 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP08979  Prostaglandin reductase 2 (PTGR2) 13.3
 LDTP04051  Nicotinamide phosphoribosyltransferase (NAMPT) 5.8
 LDTP06227  Prostaglandin reductase 1 (PTGR1) 5.2
 LDTP12013  dCTP pyrophosphatase 1 (DCTPP1) 4.3
 LDTP04247  Protein farnesyltransferase subunit beta (FNTB) 3.5
 LDTP03511  Flavin reductase (NADPH) (BLVRB) 3.1
 LDTP10318  Ubiquitin thioesterase OTUB1 (OTUB1) 2.5
 LDTP00343  Pyridoxal kinase (PDXK) 2.3
 LDTP02693  Acylamino-acid-releasing enzyme (APEH) 2.3
 LDTP12190  NmrA-like family domain-containing protein 1 (NMRAL1) 2.3
Other
Click to Show/Hide to Show 5 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03030  Annexin A7 (ANXA7) 3.5
 LDTP03520  Phosphatidylethanolamine-binding protein 1 (PEBP1) 2.9
 LDTP02125  Keratin, type II cytoskeletal 8 (KRT8) 2.3
 LDTP04544  F-actin-capping protein subunit alpha-1 (CAPZA1) 2.2
 LDTP01075  Protein CutA (CUTA) 2.1

References

1 Mapping the protein interaction landscape for fully functionalized small-molecule probes in human cells. J Am Chem Soc. 2014 Jul 30;136(30):10777-82. doi: 10.1021/ja505517t. Epub 2014 Jul 21.