Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name FBP2  Probe Info 
Probe concentration 100 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
LFQ
Competitor Name Tranylcypromine  Competitor Info 
Competitor Concentration 1 mM
In Vivo Experiment Model Model Type Living cell
Derived Tissue Adrenal
Disease Model Bone marrow neuroblastoma [ICD11: 2A00]
Model Name Human neuroblastoma cells (SH-SY5Y)

Interaction Altas of This Experiment [1]

Enzyme
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Target ID Target Name Binding Ratio
 LDTP02198  Cathepsin D (CTSD) 2.4
Immunoglobulin
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Target ID Target Name Binding Ratio
 LDTP05973  CD166 antigen (ALCAM) 2.3
Other
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Target ID Target Name Binding Ratio
 LDTP13985  Small ribosomal subunit protein mS23 (MRPS23) 3.5

References

1 Tranylcypromine specificity for monoamine oxidase is limited by promiscuous protein labelling and lysosomal trapping. RSC Chem Biol. 2020 Aug 12;1(4):209-213. doi: 10.1039/d0cb00048e. eCollection 2020 Oct 1.
Mass spectrometry data entry: PXD018580