Details of the Target

General Information of Target

Target ID LDTP14664
Target Name Homeobox protein Hox-A6 (HOXA6)
Gene Name HOXA6
Gene ID 3203
Synonyms
HOX1B; Homeobox protein Hox-A6; Homeobox protein Hox-1B
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MLLCFRFGNQSMKRENFTLITDFVFQGFSSFHEQQITLFGVFLALYILTLAGNIIIVTII
RMDLHLHTPMYFFLSMLSTSETVYTLVILPRMLSSLVGMSQPISLAGCATQMFFFVTFGI
TNCFLLTAMGYDRYVAICNPLRYMVIMNKRLRIQLVLGACSIGLIVAITQVTSVFRLPFC
ARKVPHFFCDIRPVMKLSCIDTTVNEILTLIISVLVLVVPMGLVFISYVLIISTILKIAS
VEGRKKAFATCASHLTVVIVHYSCASIAYLKPKSENTREHDQLISVTYTVITPLLNPVVY
TLRNKEVKDALCRAVGGKFS
Target Bioclass
Transcription factor
Family
Antp homeobox family
Subcellular location
Nucleus
Function Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Uniprot ID
P31267
Ensemble ID
ENST00000222728.3
HGNC ID
HGNC:5107

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
Acrolein
 Probe Info  		N.A.  LDD0225  [1]
DBIA
 Probe Info  		C146(0.87)  LDD1512  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0259  AC14 HEK-293T C146(0.87)  LDD1512  [2]
 LDCM0270  AC15 HEK-293T C146(1.29)  LDD1513  [2]
 LDCM0282  AC22 HEK-293T C146(1.02)  LDD1521  [2]
 LDCM0283  AC23 HEK-293T C146(0.95)  LDD1522  [2]
 LDCM0284  AC24 HEK-293T C146(0.85)  LDD1523  [2]
 LDCM0291  AC30 HEK-293T C146(0.89)  LDD1530  [2]
 LDCM0292  AC31 HEK-293T C146(1.37)  LDD1531  [2]
 LDCM0293  AC32 HEK-293T C146(0.94)  LDD1532  [2]
 LDCM0299  AC38 HEK-293T C146(1.05)  LDD1538  [2]
 LDCM0300  AC39 HEK-293T C146(1.03)  LDD1539  [2]
 LDCM0302  AC40 HEK-293T C146(1.07)  LDD1541  [2]
 LDCM0308  AC46 HEK-293T C146(1.00)  LDD1547  [2]
 LDCM0309  AC47 HEK-293T C146(1.00)  LDD1548  [2]
 LDCM0310  AC48 HEK-293T C146(1.07)  LDD1549  [2]
 LDCM0317  AC54 HEK-293T C146(0.87)  LDD1556  [2]
 LDCM0318  AC55 HEK-293T C146(0.98)  LDD1557  [2]
 LDCM0319  AC56 HEK-293T C146(0.99)  LDD1558  [2]
 LDCM0323  AC6 HEK-293T C146(1.06)  LDD1562  [2]
 LDCM0326  AC62 HEK-293T C146(0.86)  LDD1565  [2]
 LDCM0327  AC63 HEK-293T C146(0.83)  LDD1566  [2]
 LDCM0328  AC64 HEK-293T C146(1.16)  LDD1567  [2]
 LDCM0334  AC7 HEK-293T C146(0.96)  LDD1568  [2]
 LDCM0345  AC8 HEK-293T C146(0.82)  LDD1569  [2]
 LDCM0275  AKOS034007705 HEK-293T C146(1.15)  LDD1514  [2]
 LDCM0368  CL10 HEK-293T C146(1.18)  LDD1572  [2]
 LDCM0372  CL103 HEK-293T C146(1.35)  LDD1576  [2]
 LDCM0376  CL107 HEK-293T C146(0.97)  LDD1580  [2]
 LDCM0379  CL11 HEK-293T C146(0.92)  LDD1583  [2]
 LDCM0381  CL111 HEK-293T C146(1.25)  LDD1585  [2]
 LDCM0385  CL115 HEK-293T C146(0.93)  LDD1589  [2]
 LDCM0389  CL119 HEK-293T C146(0.99)  LDD1593  [2]
 LDCM0390  CL12 HEK-293T C146(1.12)  LDD1594  [2]
 LDCM0394  CL123 HEK-293T C146(1.02)  LDD1598  [2]
 LDCM0398  CL127 HEK-293T C146(1.19)  LDD1602  [2]
 LDCM0402  CL15 HEK-293T C146(1.13)  LDD1606  [2]
 LDCM0410  CL22 HEK-293T C146(0.86)  LDD1614  [2]
 LDCM0411  CL23 HEK-293T C146(0.91)  LDD1615  [2]
 LDCM0412  CL24 HEK-293T C146(1.18)  LDD1616  [2]
 LDCM0415  CL27 HEK-293T C146(1.36)  LDD1619  [2]
 LDCM0418  CL3 HEK-293T C146(1.10)  LDD1622  [2]
 LDCM0423  CL34 HEK-293T C146(1.10)  LDD1627  [2]
 LDCM0424  CL35 HEK-293T C146(1.30)  LDD1628  [2]
 LDCM0425  CL36 HEK-293T C146(0.92)  LDD1629  [2]
 LDCM0428  CL39 HEK-293T C146(1.39)  LDD1632  [2]
 LDCM0436  CL46 HEK-293T C146(0.87)  LDD1640  [2]
 LDCM0437  CL47 HEK-293T C146(1.79)  LDD1641  [2]
 LDCM0438  CL48 HEK-293T C146(0.99)  LDD1642  [2]
 LDCM0449  CL58 HEK-293T C146(0.95)  LDD1652  [2]
 LDCM0450  CL59 HEK-293T C146(0.97)  LDD1653  [2]
 LDCM0452  CL60 HEK-293T C146(1.24)  LDD1655  [2]
 LDCM0455  CL63 HEK-293T C146(1.34)  LDD1658  [2]
 LDCM0463  CL70 HEK-293T C146(0.78)  LDD1666  [2]
 LDCM0464  CL71 HEK-293T C146(1.05)  LDD1667  [2]
 LDCM0465  CL72 HEK-293T C146(1.10)  LDD1668  [2]
 LDCM0476  CL82 HEK-293T C146(1.15)  LDD1679  [2]
 LDCM0477  CL83 HEK-293T C146(0.91)  LDD1680  [2]
 LDCM0478  CL84 HEK-293T C146(0.75)  LDD1681  [2]
 LDCM0481  CL87 HEK-293T C146(0.92)  LDD1684  [2]
 LDCM0489  CL94 HEK-293T C146(1.28)  LDD1692  [2]
 LDCM0490  CL95 HEK-293T C146(1.40)  LDD1693  [2]
 LDCM0491  CL96 HEK-293T C146(1.57)  LDD1694  [2]
 LDCM0494  CL99 HEK-293T C146(1.23)  LDD1697  [2]
 LDCM0495  E2913 HEK-293T C146(1.11)  LDD1698  [2]
 LDCM0468  Fragment33 HEK-293T C146(1.16)  LDD1671  [2]
 LDCM0109  NEM HeLa N.A.  LDD0225  [1]

References

1 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
2 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402