Details of the Target

General Information of Target

Target ID LDTP12584
Target Name Zinc finger protein 275 (ZNF275)
Gene Name ZNF275
Synonyms
Zinc finger protein 275
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MRSCLWRCRHLSQGVQWSLLLAVLVFFLFALPSFIKEPQTKPSRHQRTENIKERSLQSLA
KPKSQAPTRARRTTIYAEPVPENNALNTQTQPKAHTTGDRGKEANQAPPEEQDKVPHTAQ
RAAWKSPEKEKTMVNTLSPRGQDAGMASGRTEAQSWKSQDTKTTQGNGGQTRKLTASRTV
SEKHQGKAATTAKTLIPKSQHRMLAPTGAVSTRTRQKGVTTAVIPPKEKKPQATPPPAPF
QSPTTQRNQRLKAANFKSEPRWDFEEKYSFEIGGLQTTCPDSVKIKASKSLWLQKLFLPN
LTLFLDSRHFNQSEWDRLEHFAPPFGFMELNYSLVQKVVTRFPPVPQQQLLLASLPAGSL
RCITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQ
SLLILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLMNQTVMSKNLFWFRHRPQEAFR
EALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSAYG
FITEGHERFSDHYYDTSWKRLIFYINHDFKLEREVWKRLHDEGIIRLYQRPGPGTAKAKN
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
Q9NSD4
Ensemble ID
ENST00000370249.3
HGNC ID
HGNC:13069

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C267(0.94); C270(0.94)  LDD0531  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C267(0.94); C270(0.94)  LDD0531  [1]
 LDCM0215  AC10 HCT 116 C267(1.08); C270(1.08)  LDD0532  [1]
 LDCM0216  AC100 HEK-293T C267(0.85); C270(0.85)  LDD0814  [1]
 LDCM0217  AC101 HEK-293T C267(0.92); C270(0.92)  LDD0815  [1]
 LDCM0218  AC102 HEK-293T C267(0.94); C270(0.94)  LDD0816  [1]
 LDCM0219  AC103 HEK-293T C267(0.85); C270(0.85)  LDD0817  [1]
 LDCM0220  AC104 HEK-293T C267(0.81); C270(0.81)  LDD0818  [1]
 LDCM0221  AC105 HEK-293T C267(0.93); C270(0.93)  LDD0819  [1]
 LDCM0222  AC106 HEK-293T C267(1.03); C270(1.03)  LDD0820  [1]
 LDCM0223  AC107 HEK-293T C267(0.90); C270(0.90)  LDD0821  [1]
 LDCM0224  AC108 HEK-293T C267(0.78); C270(0.78)  LDD0822  [1]
 LDCM0225  AC109 HEK-293T C267(0.85); C270(0.85)  LDD0823  [1]
 LDCM0226  AC11 HCT 116 C267(1.60); C270(1.60)  LDD0543  [1]
 LDCM0227  AC110 HEK-293T C267(0.78); C270(0.78)  LDD0825  [1]
 LDCM0228  AC111 HEK-293T C267(0.87); C270(0.87)  LDD0826  [1]
 LDCM0229  AC112 HEK-293T C267(0.74); C270(0.74)  LDD0827  [1]
 LDCM0230  AC113 HCT 116 C267(1.04); C270(1.04)  LDD0547  [1]
 LDCM0231  AC114 HCT 116 C267(0.93); C270(0.93)  LDD0548  [1]
 LDCM0232  AC115 HCT 116 C267(1.04); C270(1.04)  LDD0549  [1]
 LDCM0233  AC116 HCT 116 C267(0.98); C270(0.98)  LDD0550  [1]
 LDCM0234  AC117 HCT 116 C267(1.00); C270(1.00)  LDD0551  [1]
 LDCM0235  AC118 HCT 116 C267(0.98); C270(0.98)  LDD0552  [1]
 LDCM0236  AC119 HCT 116 C267(1.07); C270(1.07)  LDD0553  [1]
 LDCM0237  AC12 HCT 116 C267(1.19); C270(1.19)  LDD0554  [1]
 LDCM0238  AC120 HCT 116 C267(0.86); C270(0.86)  LDD0555  [1]
 LDCM0239  AC121 HCT 116 C267(0.79); C270(0.79)  LDD0556  [1]
 LDCM0240  AC122 HCT 116 C267(1.12); C270(1.12)  LDD0557  [1]
 LDCM0241  AC123 HCT 116 C267(0.78); C270(0.78)  LDD0558  [1]
 LDCM0242  AC124 HCT 116 C267(0.85); C270(0.85)  LDD0559  [1]
 LDCM0243  AC125 HCT 116 C267(0.85); C270(0.85)  LDD0560  [1]
 LDCM0244  AC126 HCT 116 C267(0.85); C270(0.85)  LDD0561  [1]
 LDCM0245  AC127 HCT 116 C267(0.83); C270(0.83)  LDD0562  [1]
 LDCM0259  AC14 HCT 116 C267(1.28); C270(1.28)  LDD0576  [1]
 LDCM0270  AC15 HCT 116 C267(1.31); C270(1.31)  LDD0587  [1]
 LDCM0279  AC2 HCT 116 C267(1.03); C270(1.03)  LDD0596  [1]
 LDCM0285  AC25 HEK-293T C211(0.76); C214(0.76); C267(0.76); C270(0.76)  LDD0883  [1]
 LDCM0286  AC26 HEK-293T C211(0.88); C214(0.88); C267(0.79); C270(0.79)  LDD0884  [1]
 LDCM0287  AC27 HEK-293T C211(0.83); C214(0.83); C267(1.04); C270(1.04)  LDD0885  [1]
 LDCM0288  AC28 HEK-293T C211(0.84); C214(0.84); C267(0.84); C270(0.84)  LDD0886  [1]
 LDCM0289  AC29 HEK-293T C211(0.75); C214(0.75); C267(1.06); C270(1.06)  LDD0887  [1]
 LDCM0290  AC3 HCT 116 C267(1.00); C270(1.00)  LDD0607  [1]
 LDCM0291  AC30 HEK-293T C211(0.93); C214(0.93); C267(0.89); C270(0.89)  LDD0889  [1]
 LDCM0292  AC31 HEK-293T C211(0.87); C214(0.87); C267(0.79); C270(0.79)  LDD0890  [1]
 LDCM0293  AC32 HEK-293T C211(0.88); C214(0.88); C267(0.89); C270(0.89)  LDD0891  [1]
 LDCM0294  AC33 HEK-293T C211(0.88); C214(0.88); C267(0.87); C270(0.87)  LDD0892  [1]
 LDCM0295  AC34 HEK-293T C211(0.92); C214(0.92); C267(0.82); C270(0.82)  LDD0893  [1]
 LDCM0296  AC35 HEK-293T C211(1.11); C214(1.11); C267(1.18); C270(1.18)  LDD0894  [1]
 LDCM0297  AC36 HEK-293T C211(0.69); C214(0.69); C267(0.76); C270(0.76)  LDD0895  [1]
 LDCM0298  AC37 HEK-293T C211(0.82); C214(0.82); C267(0.85); C270(0.85)  LDD0896  [1]
 LDCM0299  AC38 HEK-293T C211(1.30); C214(1.30); C267(1.16); C270(1.16)  LDD0897  [1]
 LDCM0300  AC39 HEK-293T C211(1.55); C214(1.55); C267(1.31); C270(1.31)  LDD0898  [1]
 LDCM0301  AC4 HCT 116 C267(0.92); C270(0.92)  LDD0618  [1]
 LDCM0302  AC40 HEK-293T C211(1.07); C214(1.07); C267(0.95); C270(0.95)  LDD0900  [1]
 LDCM0303  AC41 HEK-293T C211(1.01); C214(1.01); C267(1.24); C270(1.24)  LDD0901  [1]
 LDCM0304  AC42 HEK-293T C211(1.05); C214(1.05); C267(1.18); C270(1.18)  LDD0902  [1]
 LDCM0305  AC43 HEK-293T C211(0.94); C214(0.94); C267(1.10); C270(1.10)  LDD0903  [1]
 LDCM0306  AC44 HEK-293T C211(1.02); C214(1.02); C267(1.02); C270(1.02)  LDD0904  [1]
 LDCM0307  AC45 HEK-293T C211(0.95); C214(0.95); C267(1.19); C270(1.19)  LDD0905  [1]
 LDCM0308  AC46 HEK-293T C211(1.07); C214(1.07); C267(0.92); C270(0.92)  LDD0906  [1]
 LDCM0309  AC47 HEK-293T C211(1.13); C214(1.13); C267(0.84); C270(0.84)  LDD0907  [1]
 LDCM0310  AC48 HEK-293T C211(1.05); C214(1.05); C267(0.84); C270(0.84)  LDD0908  [1]
 LDCM0311  AC49 HEK-293T C211(1.04); C214(1.04); C267(0.85); C270(0.85)  LDD0909  [1]
 LDCM0312  AC5 HCT 116 C267(0.93); C270(0.93)  LDD0629  [1]
 LDCM0313  AC50 HEK-293T C211(0.97); C214(0.97); C267(0.93); C270(0.93)  LDD0911  [1]
 LDCM0314  AC51 HEK-293T C211(1.26); C214(1.26); C267(0.99); C270(0.99)  LDD0912  [1]
 LDCM0315  AC52 HEK-293T C211(1.23); C214(1.23); C267(0.86); C270(0.86)  LDD0913  [1]
 LDCM0316  AC53 HEK-293T C211(0.95); C214(0.95); C267(0.80); C270(0.80)  LDD0914  [1]
 LDCM0317  AC54 HEK-293T C211(1.27); C214(1.27); C267(1.06); C270(1.06)  LDD0915  [1]
 LDCM0318  AC55 HEK-293T C211(1.20); C214(1.20); C267(1.05); C270(1.05)  LDD0916  [1]
 LDCM0319  AC56 HEK-293T C211(1.10); C214(1.10); C267(0.90); C270(0.90)  LDD0917  [1]
 LDCM0323  AC6 HCT 116 C267(0.96); C270(0.96)  LDD0640  [1]
 LDCM0332  AC68 HCT 116 C267(0.79); C270(0.79)  LDD0649  [1]
 LDCM0333  AC69 HCT 116 C267(0.78); C270(0.78)  LDD0650  [1]
 LDCM0334  AC7 HCT 116 C267(0.99); C270(0.99)  LDD0651  [1]
 LDCM0335  AC70 HCT 116 C267(0.91); C270(0.91)  LDD0652  [1]
 LDCM0336  AC71 HCT 116 C267(0.97); C270(0.97)  LDD0653  [1]
 LDCM0337  AC72 HCT 116 C267(0.97); C270(0.97)  LDD0654  [1]
 LDCM0338  AC73 HCT 116 C267(1.11); C270(1.11)  LDD0655  [1]
 LDCM0339  AC74 HCT 116 C267(1.07); C270(1.07)  LDD0656  [1]
 LDCM0340  AC75 HCT 116 C267(0.91); C270(0.91)  LDD0657  [1]
 LDCM0341  AC76 HCT 116 C267(0.91); C270(0.91)  LDD0658  [1]
 LDCM0342  AC77 HCT 116 C267(0.92); C270(0.92)  LDD0659  [1]
 LDCM0343  AC78 HCT 116 C267(0.91); C270(0.91)  LDD0660  [1]
 LDCM0344  AC79 HCT 116 C267(0.98); C270(0.98)  LDD0661  [1]
 LDCM0345  AC8 HCT 116 C267(1.18); C270(1.18)  LDD0662  [1]
 LDCM0346  AC80 HCT 116 C267(1.03); C270(1.03)  LDD0663  [1]
 LDCM0347  AC81 HCT 116 C267(0.96); C270(0.96)  LDD0664  [1]
 LDCM0348  AC82 HCT 116 C267(1.03); C270(1.03)  LDD0665  [1]
 LDCM0349  AC83 HEK-293T C267(0.85); C270(0.85)  LDD0947  [1]
 LDCM0350  AC84 HEK-293T C267(0.79); C270(0.79)  LDD0948  [1]
 LDCM0351  AC85 HEK-293T C267(0.75); C270(0.75)  LDD0949  [1]
 LDCM0352  AC86 HEK-293T C267(0.86); C270(0.86)  LDD0950  [1]
 LDCM0353  AC87 HEK-293T C267(0.88); C270(0.88)  LDD0951  [1]
 LDCM0354  AC88 HEK-293T C267(0.72); C270(0.72)  LDD0952  [1]
 LDCM0355  AC89 HEK-293T C267(0.91); C270(0.91)  LDD0953  [1]
 LDCM0357  AC90 HEK-293T C267(0.84); C270(0.84)  LDD0955  [1]
 LDCM0358  AC91 HEK-293T C267(0.74); C270(0.74)  LDD0956  [1]
 LDCM0359  AC92 HEK-293T C267(0.71); C270(0.71)  LDD0957  [1]
 LDCM0360  AC93 HEK-293T C267(0.76); C270(0.76)  LDD0958  [1]
 LDCM0361  AC94 HEK-293T C267(0.74); C270(0.74)  LDD0959  [1]
 LDCM0362  AC95 HEK-293T C267(0.69); C270(0.69)  LDD0960  [1]
 LDCM0363  AC96 HEK-293T C267(0.75); C270(0.75)  LDD0961  [1]
 LDCM0364  AC97 HEK-293T C267(0.74); C270(0.74)  LDD0962  [1]
 LDCM0365  AC98 HEK-293T C267(0.81); C270(0.81)  LDD0963  [1]
 LDCM0366  AC99 HEK-293T C267(0.76); C270(0.76)  LDD0964  [1]
 LDCM0248  AKOS034007472 HCT 116 C267(1.21); C270(1.21)  LDD0565  [1]
 LDCM0356  AKOS034007680 HCT 116 C267(1.23); C270(1.23)  LDD0673  [1]
 LDCM0275  AKOS034007705 HCT 116 C267(1.35); C270(1.35)  LDD0592  [1]
 LDCM0369  CL100 HCT 116 C267(1.17); C270(1.17)  LDD0686  [1]
 LDCM0370  CL101 HCT 116 C267(1.36); C270(1.36)  LDD0687  [1]
 LDCM0371  CL102 HCT 116 C267(1.10); C270(1.10)  LDD0688  [1]
 LDCM0372  CL103 HCT 116 C267(1.24); C270(1.24)  LDD0689  [1]
 LDCM0373  CL104 HCT 116 C267(1.40); C270(1.40)  LDD0690  [1]
 LDCM0382  CL112 HEK-293T C211(0.85); C214(0.85); C267(0.93); C270(0.93)  LDD0980  [1]
 LDCM0383  CL113 HEK-293T C211(0.84); C214(0.84); C267(0.87); C270(0.87)  LDD0981  [1]
 LDCM0384  CL114 HEK-293T C211(0.89); C214(0.89); C267(0.84); C270(0.84)  LDD0982  [1]
 LDCM0385  CL115 HEK-293T C211(0.97); C214(0.97); C267(0.79); C270(0.79)  LDD0983  [1]
 LDCM0386  CL116 HEK-293T C211(0.78); C214(0.78); C267(0.78); C270(0.78)  LDD0984  [1]
 LDCM0387  CL117 HEK-293T C211(1.31); C214(1.31); C267(1.15); C270(1.15)  LDD0985  [1]
 LDCM0388  CL118 HEK-293T C211(1.00); C214(1.00); C267(0.94); C270(0.94)  LDD0986  [1]
 LDCM0389  CL119 HEK-293T C211(0.94); C214(0.94); C267(1.09); C270(1.09)  LDD0987  [1]
 LDCM0391  CL120 HEK-293T C211(0.97); C214(0.97); C267(1.33); C270(1.33)  LDD0989  [1]
 LDCM0392  CL121 HEK-293T C211(0.90); C214(0.90); C267(0.81); C270(0.81)  LDD0990  [1]
 LDCM0393  CL122 HEK-293T C211(1.15); C214(1.15); C267(0.88); C270(0.88)  LDD0991  [1]
 LDCM0394  CL123 HEK-293T C211(1.12); C214(1.12); C267(0.76); C270(0.76)  LDD0992  [1]
 LDCM0395  CL124 HEK-293T C211(1.12); C214(1.12); C267(0.97); C270(0.97)  LDD0993  [1]
 LDCM0403  CL16 HCT 116 C267(1.21); C270(1.21)  LDD0720  [1]
 LDCM0404  CL17 HCT 116 C267(0.71); C270(0.71)  LDD0721  [1]
 LDCM0405  CL18 HCT 116 C267(0.86); C270(0.86)  LDD0722  [1]
 LDCM0406  CL19 HCT 116 C267(0.92); C270(0.92)  LDD0723  [1]
 LDCM0408  CL20 HCT 116 C267(1.06); C270(1.06)  LDD0725  [1]
 LDCM0409  CL21 HCT 116 C267(0.75); C270(0.75)  LDD0726  [1]
 LDCM0410  CL22 HCT 116 C267(1.12); C270(1.12)  LDD0727  [1]
 LDCM0411  CL23 HCT 116 C267(1.25); C270(1.25)  LDD0728  [1]
 LDCM0412  CL24 HCT 116 C267(1.01); C270(1.01)  LDD0729  [1]
 LDCM0413  CL25 HCT 116 C267(1.18); C270(1.18)  LDD0730  [1]
 LDCM0414  CL26 HCT 116 C267(1.50); C270(1.50)  LDD0731  [1]
 LDCM0415  CL27 HCT 116 C267(1.09); C270(1.09)  LDD0732  [1]
 LDCM0416  CL28 HCT 116 C267(1.30); C270(1.30)  LDD0733  [1]
 LDCM0417  CL29 HCT 116 C267(1.17); C270(1.17)  LDD0734  [1]
 LDCM0419  CL30 HCT 116 C267(1.32); C270(1.32)  LDD0736  [1]
 LDCM0469  CL76 HEK-293T C211(0.70); C214(0.70)  LDD1067  [1]
 LDCM0470  CL77 HEK-293T C211(0.72); C214(0.72)  LDD1068  [1]
 LDCM0471  CL78 HEK-293T C211(1.10); C214(1.10)  LDD1069  [1]
 LDCM0472  CL79 HEK-293T C211(0.61); C214(0.61)  LDD1070  [1]
 LDCM0474  CL80 HEK-293T C211(0.81); C214(0.81)  LDD1072  [1]
 LDCM0475  CL81 HEK-293T C211(0.82); C214(0.82)  LDD1073  [1]
 LDCM0476  CL82 HEK-293T C211(0.69); C214(0.69)  LDD1074  [1]
 LDCM0477  CL83 HEK-293T C211(0.79); C214(0.79)  LDD1075  [1]
 LDCM0478  CL84 HEK-293T C211(0.84); C214(0.84)  LDD1076  [1]
 LDCM0479  CL85 HEK-293T C211(1.26); C214(1.26)  LDD1077  [1]
 LDCM0480  CL86 HEK-293T C211(0.80); C214(0.80)  LDD1078  [1]
 LDCM0481  CL87 HEK-293T C211(1.06); C214(1.06)  LDD1079  [1]
 LDCM0482  CL88 HEK-293T C211(1.32); C214(1.32)  LDD1080  [1]
 LDCM0483  CL89 HEK-293T C211(0.99); C214(0.99)  LDD1081  [1]
 LDCM0485  CL90 HEK-293T C211(0.96); C214(0.96)  LDD1083  [1]
 LDCM0486  CL91 HCT 116 C267(0.82); C270(0.82)  LDD0803  [1]
 LDCM0487  CL92 HCT 116 C267(0.74); C270(0.74)  LDD0804  [1]
 LDCM0488  CL93 HCT 116 C267(0.74); C270(0.74)  LDD0805  [1]
 LDCM0489  CL94 HCT 116 C267(1.21); C270(1.21)  LDD0806  [1]
 LDCM0490  CL95 HCT 116 C267(1.11); C270(1.11)  LDD0807  [1]
 LDCM0491  CL96 HCT 116 C267(1.01); C270(1.01)  LDD0808  [1]
 LDCM0492  CL97 HCT 116 C267(1.16); C270(1.16)  LDD0809  [1]
 LDCM0493  CL98 HCT 116 C267(0.79); C270(0.79)  LDD0810  [1]
 LDCM0494  CL99 HCT 116 C267(0.88); C270(0.88)  LDD0811  [1]

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.