Details of the Target

General Information of Target

Target ID LDTP11821
Target Name Golgin-45 (BLZF1)
Gene Name BLZF1
Gene ID 8548
Synonyms
JEM1; Golgin-45; Basic leucine zipper nuclear factor 1; JEM-1; p45 basic leucine-zipper nuclear factor
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MDRPDEGPPAKTRRLSSSESPQRDPPPPPPPPPLLRLPLPPPQQRPRLQEETEAAQVLAD
MRGVGLGPALPPPPPYVILEEGGIRAYFTLGAECPGWDSTIESGYGEAPPPTESLEALPT
PEASGGSLEIDFQVVQSSSFGGEGALETCSAVGWAPQRLVDPKSKEEAIIIVEDEDEDER
ESMRSSRRRRRRRRRKQRKVKRESRERNAERMESILQALEDIQLDLEAVNIKAGKAFLRL
KRKFIQMRRPFLERRDLIIQHIPGFWVKAFLNHPRISILINRRDEDIFRYLTNLQVQDLR
HISMGYKMKLYFQTNPYFTNMVIVKEFQRNRSGRLVSHSTPIRWHRGQEPQARRHGNQDA
SHSFFSWFSNHSLPEADRIAEIIKNDLWVNPLRYYLRERGSRIKRKKQEMKKRKTRGRCE
VVIMEDAPDYYAVEDIFSEISDIDETIHDIKISDFMETTDYFETTDNEITDINENICDSE
NPDHNEVPNNETTDNNESADDHETTDNNESADDNNENPEDNNKNTDDNEENPNNNENTYG
NNFFKGGFWGSHGNNQDSSDSDNEADEASDDEDNDGNEGDNEGSDDDGNEGDNEGSDDDD
RDIEYYEKVIEDFDKDQADYEDVIEIISDESVEEEGIEEGIQQDEDIYEEGNYEEEGSED
VWEEGEDSDDSDLEDVLQVPNGWANPGKRGKTG
Target Bioclass
Transcription factor
Subcellular location
Cytoplasm; Nucleus; Golgi apparatus membrane
Function Required for normal Golgi structure and for protein transport from the endoplasmic reticulum (ER) through the Golgi apparatus to the cell surface.
Uniprot ID
Q9H2G9
Ensemble ID
ENST00000329281.6
HGNC ID
HGNC:1065

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
AGS SNV: p.K162T .
HCT116 SNV: p.N191D .
NCIH1666 SNV: p.N128S .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info  		K218(10.00)  LDD0277  [1]
DBIA
 Probe Info  		C349(2.83)  LDD3312  [2]
IPM
 Probe Info  		N.A.  LDD0147  [3]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C349(1.03)  LDD1507  [4]
 LDCM0215  AC10 HEK-293T C349(1.02); C329(0.92)  LDD1508  [4]
 LDCM0226  AC11 HEK-293T C349(0.98)  LDD1509  [4]
 LDCM0237  AC12 HEK-293T C349(0.97)  LDD1510  [4]
 LDCM0259  AC14 HEK-293T C349(1.00); C329(0.80)  LDD1512  [4]
 LDCM0270  AC15 HEK-293T C349(1.04)  LDD1513  [4]
 LDCM0276  AC17 HEK-293T C349(1.05)  LDD1515  [4]
 LDCM0277  AC18 HEK-293T C349(1.03); C329(1.01)  LDD1516  [4]
 LDCM0278  AC19 HEK-293T C349(1.09)  LDD1517  [4]
 LDCM0279  AC2 HEK-293T C349(1.00); C329(0.99)  LDD1518  [4]
 LDCM0280  AC20 HEK-293T C349(1.01)  LDD1519  [4]
 LDCM0281  AC21 HEK-293T C349(1.07)  LDD1520  [4]
 LDCM0282  AC22 HEK-293T C349(1.00); C329(0.88)  LDD1521  [4]
 LDCM0283  AC23 HEK-293T C349(0.96)  LDD1522  [4]
 LDCM0285  AC25 HEK-293T C349(1.03)  LDD1524  [4]
 LDCM0286  AC26 HEK-293T C349(0.95); C329(0.90)  LDD1525  [4]
 LDCM0287  AC27 HEK-293T C349(0.98)  LDD1526  [4]
 LDCM0288  AC28 HEK-293T C349(0.94)  LDD1527  [4]
 LDCM0289  AC29 HEK-293T C349(0.92)  LDD1528  [4]
 LDCM0290  AC3 HEK-293T C349(1.13)  LDD1529  [4]
 LDCM0291  AC30 HEK-293T C349(0.99); C329(1.06)  LDD1530  [4]
 LDCM0292  AC31 HEK-293T C349(0.96)  LDD1531  [4]
 LDCM0294  AC33 HEK-293T C349(0.95)  LDD1533  [4]
 LDCM0295  AC34 HEK-293T C349(1.01); C329(0.99)  LDD1534  [4]
 LDCM0296  AC35 HEK-293T C349(1.04)  LDD1535  [4]
 LDCM0297  AC36 HEK-293T C349(0.92)  LDD1536  [4]
 LDCM0298  AC37 HEK-293T C349(0.95)  LDD1537  [4]
 LDCM0299  AC38 HEK-293T C349(1.01); C329(0.87)  LDD1538  [4]
 LDCM0300  AC39 HEK-293T C349(0.95)  LDD1539  [4]
 LDCM0301  AC4 HEK-293T C349(1.10)  LDD1540  [4]
 LDCM0303  AC41 HEK-293T C349(1.01)  LDD1542  [4]
 LDCM0304  AC42 HEK-293T C349(1.02); C329(0.97)  LDD1543  [4]
 LDCM0305  AC43 HEK-293T C349(1.01)  LDD1544  [4]
 LDCM0306  AC44 HEK-293T C349(1.12)  LDD1545  [4]
 LDCM0307  AC45 HEK-293T C349(0.94)  LDD1546  [4]
 LDCM0308  AC46 HEK-293T C349(1.05); C329(0.91)  LDD1547  [4]
 LDCM0309  AC47 HEK-293T C349(0.99)  LDD1548  [4]
 LDCM0311  AC49 HEK-293T C349(1.03)  LDD1550  [4]
 LDCM0312  AC5 HEK-293T C349(1.05)  LDD1551  [4]
 LDCM0313  AC50 HEK-293T C349(0.95); C329(1.11)  LDD1552  [4]
 LDCM0314  AC51 HEK-293T C349(1.04)  LDD1553  [4]
 LDCM0315  AC52 HEK-293T C349(1.08)  LDD1554  [4]
 LDCM0316  AC53 HEK-293T C349(0.99)  LDD1555  [4]
 LDCM0317  AC54 HEK-293T C349(0.97); C329(0.98)  LDD1556  [4]
 LDCM0318  AC55 HEK-293T C349(0.98)  LDD1557  [4]
 LDCM0320  AC57 HEK-293T C349(1.11)  LDD1559  [4]
 LDCM0321  AC58 HEK-293T C349(1.07); C329(1.07)  LDD1560  [4]
 LDCM0322  AC59 HEK-293T C349(0.94)  LDD1561  [4]
 LDCM0323  AC6 HEK-293T C349(1.16); C329(0.87)  LDD1562  [4]
 LDCM0324  AC60 HEK-293T C349(1.03)  LDD1563  [4]
 LDCM0325  AC61 HEK-293T C349(1.05)  LDD1564  [4]
 LDCM0326  AC62 HEK-293T C349(0.98); C329(0.99)  LDD1565  [4]
 LDCM0327  AC63 HEK-293T C349(0.99)  LDD1566  [4]
 LDCM0334  AC7 HEK-293T C349(0.96)  LDD1568  [4]
 LDCM0248  AKOS034007472 HEK-293T C349(1.00)  LDD1511  [4]
 LDCM0356  AKOS034007680 HEK-293T C349(0.98)  LDD1570  [4]
 LDCM0367  CL1 HEK-293T C349(0.86)  LDD1571  [4]
 LDCM0368  CL10 HEK-293T C349(1.03); C329(0.77)  LDD1572  [4]
 LDCM0369  CL100 HEK-293T C349(1.12)  LDD1573  [4]
 LDCM0370  CL101 HEK-293T C349(0.90)  LDD1574  [4]
 LDCM0371  CL102 HEK-293T C349(0.99)  LDD1575  [4]
 LDCM0372  CL103 HEK-293T C349(0.98)  LDD1576  [4]
 LDCM0373  CL104 HEK-293T C349(1.10)  LDD1577  [4]
 LDCM0374  CL105 HEK-293T C349(0.96)  LDD1578  [4]
 LDCM0375  CL106 HEK-293T C349(0.99)  LDD1579  [4]
 LDCM0376  CL107 HEK-293T C349(0.98)  LDD1580  [4]
 LDCM0377  CL108 HEK-293T C349(1.09)  LDD1581  [4]
 LDCM0378  CL109 HEK-293T C349(0.97)  LDD1582  [4]
 LDCM0379  CL11 HEK-293T C349(0.91)  LDD1583  [4]
 LDCM0380  CL110 HEK-293T C349(0.94)  LDD1584  [4]
 LDCM0381  CL111 HEK-293T C349(0.98)  LDD1585  [4]
 LDCM0382  CL112 HEK-293T C349(1.11)  LDD1586  [4]
 LDCM0383  CL113 HEK-293T C349(0.92)  LDD1587  [4]
 LDCM0384  CL114 HEK-293T C349(0.94)  LDD1588  [4]
 LDCM0385  CL115 HEK-293T C349(1.07)  LDD1589  [4]
 LDCM0386  CL116 HEK-293T C349(1.20)  LDD1590  [4]
 LDCM0387  CL117 HEK-293T C349(0.98)  LDD1591  [4]
 LDCM0388  CL118 HEK-293T C349(0.98)  LDD1592  [4]
 LDCM0389  CL119 HEK-293T C349(1.03)  LDD1593  [4]
 LDCM0391  CL120 HEK-293T C349(1.08)  LDD1595  [4]
 LDCM0392  CL121 HEK-293T C349(1.00)  LDD1596  [4]
 LDCM0393  CL122 HEK-293T C349(0.95)  LDD1597  [4]
 LDCM0394  CL123 HEK-293T C349(1.00)  LDD1598  [4]
 LDCM0395  CL124 HEK-293T C349(1.10)  LDD1599  [4]
 LDCM0396  CL125 HEK-293T C349(0.96)  LDD1600  [4]
 LDCM0397  CL126 HEK-293T C349(1.04)  LDD1601  [4]
 LDCM0398  CL127 HEK-293T C349(1.01)  LDD1602  [4]
 LDCM0399  CL128 HEK-293T C349(1.13)  LDD1603  [4]
 LDCM0400  CL13 HEK-293T C349(0.99)  LDD1604  [4]
 LDCM0401  CL14 HEK-293T C349(1.02)  LDD1605  [4]
 LDCM0402  CL15 HEK-293T C349(1.04)  LDD1606  [4]
 LDCM0403  CL16 HEK-293T C349(1.11)  LDD1607  [4]
 LDCM0404  CL17 HEK-293T C349(1.06)  LDD1608  [4]
 LDCM0405  CL18 HEK-293T C349(0.96); C329(1.25)  LDD1609  [4]
 LDCM0406  CL19 HEK-293T C349(0.97)  LDD1610  [4]
 LDCM0407  CL2 HEK-293T C349(0.98)  LDD1611  [4]
 LDCM0408  CL20 HEK-293T C349(0.94)  LDD1612  [4]
 LDCM0409  CL21 HEK-293T C349(1.02)  LDD1613  [4]
 LDCM0410  CL22 HEK-293T C349(0.96); C329(1.13)  LDD1614  [4]
 LDCM0411  CL23 HEK-293T C349(0.96)  LDD1615  [4]
 LDCM0413  CL25 HEK-293T C349(0.80)  LDD1617  [4]
 LDCM0414  CL26 HEK-293T C349(0.94)  LDD1618  [4]
 LDCM0415  CL27 HEK-293T C349(0.97)  LDD1619  [4]
 LDCM0416  CL28 HEK-293T C349(1.09)  LDD1620  [4]
 LDCM0417  CL29 HEK-293T C349(1.00)  LDD1621  [4]
 LDCM0418  CL3 HEK-293T C349(1.07)  LDD1622  [4]
 LDCM0419  CL30 HEK-293T C349(0.99); C329(0.99)  LDD1623  [4]
 LDCM0420  CL31 HEK-293T C349(0.94)  LDD1624  [4]
 LDCM0421  CL32 HEK-293T C349(0.94)  LDD1625  [4]
 LDCM0422  CL33 HEK-293T C349(0.98)  LDD1626  [4]
 LDCM0423  CL34 HEK-293T C349(0.98); C329(0.92)  LDD1627  [4]
 LDCM0424  CL35 HEK-293T C349(1.01)  LDD1628  [4]
 LDCM0426  CL37 HEK-293T C349(0.88)  LDD1630  [4]
 LDCM0428  CL39 HEK-293T C349(1.01)  LDD1632  [4]
 LDCM0429  CL4 HEK-293T C349(1.05)  LDD1633  [4]
 LDCM0430  CL40 HEK-293T C349(1.09)  LDD1634  [4]
 LDCM0431  CL41 HEK-293T C349(0.94)  LDD1635  [4]
 LDCM0432  CL42 HEK-293T C349(0.96); C329(1.05)  LDD1636  [4]
 LDCM0433  CL43 HEK-293T C349(0.89)  LDD1637  [4]
 LDCM0434  CL44 HEK-293T C349(1.12)  LDD1638  [4]
 LDCM0435  CL45 HEK-293T C349(1.17)  LDD1639  [4]
 LDCM0436  CL46 HEK-293T C349(1.01); C329(0.87)  LDD1640  [4]
 LDCM0437  CL47 HEK-293T C349(0.98)  LDD1641  [4]
 LDCM0439  CL49 HEK-293T C349(0.89)  LDD1643  [4]
 LDCM0440  CL5 HEK-293T C349(1.00)  LDD1644  [4]
 LDCM0441  CL50 HEK-293T C349(1.01)  LDD1645  [4]
 LDCM0443  CL52 HEK-293T C349(1.08)  LDD1646  [4]
 LDCM0444  CL53 HEK-293T C349(0.95)  LDD1647  [4]
 LDCM0445  CL54 HEK-293T C349(0.98); C329(0.99)  LDD1648  [4]
 LDCM0446  CL55 HEK-293T C349(0.96)  LDD1649  [4]
 LDCM0447  CL56 HEK-293T C349(0.95)  LDD1650  [4]
 LDCM0448  CL57 HEK-293T C349(1.07)  LDD1651  [4]
 LDCM0449  CL58 HEK-293T C349(1.05); C329(0.86)  LDD1652  [4]
 LDCM0450  CL59 HEK-293T C349(0.95)  LDD1653  [4]
 LDCM0451  CL6 HEK-293T C349(1.03); C329(1.08)  LDD1654  [4]
 LDCM0453  CL61 HEK-293T C349(0.88)  LDD1656  [4]
 LDCM0454  CL62 HEK-293T C349(0.97)  LDD1657  [4]
 LDCM0455  CL63 HEK-293T C349(0.95)  LDD1658  [4]
 LDCM0456  CL64 HEK-293T C349(1.07)  LDD1659  [4]
 LDCM0457  CL65 HEK-293T C349(1.02)  LDD1660  [4]
 LDCM0458  CL66 HEK-293T C349(0.99); C329(1.12)  LDD1661  [4]
 LDCM0459  CL67 HEK-293T C349(0.92)  LDD1662  [4]
 LDCM0460  CL68 HEK-293T C349(1.05)  LDD1663  [4]
 LDCM0461  CL69 HEK-293T C349(1.03)  LDD1664  [4]
 LDCM0462  CL7 HEK-293T C349(0.97)  LDD1665  [4]
 LDCM0463  CL70 HEK-293T C349(1.03); C329(0.88)  LDD1666  [4]
 LDCM0464  CL71 HEK-293T C349(1.02)  LDD1667  [4]
 LDCM0466  CL73 HEK-293T C349(0.85)  LDD1669  [4]
 LDCM0467  CL74 HEK-293T C349(0.96)  LDD1670  [4]
 LDCM0469  CL76 HEK-293T C349(1.12)  LDD1672  [4]
 LDCM0470  CL77 HEK-293T C349(1.13)  LDD1673  [4]
 LDCM0471  CL78 HEK-293T C349(0.98); C329(1.01)  LDD1674  [4]
 LDCM0472  CL79 HEK-293T C349(0.95)  LDD1675  [4]
 LDCM0473  CL8 HEK-293T C349(0.93)  LDD1676  [4]
 LDCM0474  CL80 HEK-293T C349(0.97)  LDD1677  [4]
 LDCM0475  CL81 HEK-293T C349(1.06)  LDD1678  [4]
 LDCM0476  CL82 HEK-293T C349(1.11); C329(0.95)  LDD1679  [4]
 LDCM0477  CL83 HEK-293T C349(0.99)  LDD1680  [4]
 LDCM0479  CL85 HEK-293T C349(0.91)  LDD1682  [4]
 LDCM0480  CL86 HEK-293T C349(0.98)  LDD1683  [4]
 LDCM0481  CL87 HEK-293T C349(0.99)  LDD1684  [4]
 LDCM0482  CL88 HEK-293T C349(1.11)  LDD1685  [4]
 LDCM0483  CL89 HEK-293T C349(1.08)  LDD1686  [4]
 LDCM0484  CL9 HEK-293T C349(1.18)  LDD1687  [4]
 LDCM0485  CL90 HEK-293T C349(1.03); C329(0.93)  LDD1688  [4]
 LDCM0486  CL91 HEK-293T C349(1.04)  LDD1689  [4]
 LDCM0487  CL92 HEK-293T C349(0.92)  LDD1690  [4]
 LDCM0488  CL93 HEK-293T C349(1.04)  LDD1691  [4]
 LDCM0489  CL94 HEK-293T C349(1.04); C329(0.90)  LDD1692  [4]
 LDCM0490  CL95 HEK-293T C349(1.04)  LDD1693  [4]
 LDCM0492  CL97 HEK-293T C349(0.92)  LDD1695  [4]
 LDCM0493  CL98 HEK-293T C349(0.96)  LDD1696  [4]
 LDCM0494  CL99 HEK-293T C349(0.98)  LDD1697  [4]
 LDCM0495  E2913 HEK-293T C349(1.01)  LDD1698  [4]
 LDCM0468  Fragment33 HEK-293T C349(0.97)  LDD1671  [4]
 LDCM0427  Fragment51 HEK-293T C349(1.02)  LDD1631  [4]
 LDCM0022  KB02 A2058 C349(2.32)  LDD2253  [2]
 LDCM0023  KB03 A2058 C349(4.05)  LDD2670  [2]
 LDCM0024  KB05 HMCB C349(2.83)  LDD3312  [2]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 23 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
5'-AMP-activated protein kinase subunit beta-2 (PRKAB2) 5'-AMP-activated protein kinase beta subunit family O43741
Replication factor C subunit 5 (RFC5) Activator 1 small subunits family P40937
DNA-directed RNA polymerases I and III subunit RPAC1 (POLR1C) Archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family O15160
Poly [ADP-ribose] polymerase tankyrase-1 (TNKS) ARTD/PARP family O95271
General transcription and DNA repair factor IIH helicase subunit XPB (ERCC3) Helicase family P19447
Histone acetyltransferase KAT5 (KAT5) MYST (SAS/MOZ) family Q92993
Protein N-terminal glutamine amidohydrolase (NTAQ1) NTAQ1 family Q96HA8
Proteasome subunit alpha type-1 (PSMA1) Peptidase T1A family P25786
Serine/threonine-protein kinase N1 (PKN1) AGC Ser/Thr protein kinase family Q16512
Cyclin-dependent kinase 18 (CDK18) CMGC Ser/Thr protein kinase family Q07002
Fibroblast growth factor receptor 3 (FGFR3) Tyr protein kinase family P22607
Tensin-2 (TNS2) PTEN phosphatase protein family Q63HR2
Ras-related protein Rab-2A (RAB2A) Rab family P61019
Ras-related protein Rab-2B (RAB2B) Rab family Q8WUD1
Ras-related protein Rab-39A (RAB39A) Rab family Q14964
GTPase HRas (HRAS) Ras family P01112
GTP-binding protein GEM (GEM) RGK family P55040
Rho-related GTP-binding protein RhoJ (RHOJ) Rho family Q9H4E5
Kinesin-like protein KIF9 (KIF9) Kinesin family Q9HAQ2
Tripartite motif-containing protein 59 (TRIM59) TRIM/RBCC family Q8IWR1
E3 ubiquitin-protein ligase LNX (LNX1) . Q8TBB1
Probable E3 ubiquitin-protein ligase makorin-3 (MKRN3) . Q13064
Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2 (TSTD2) . Q5T7W7
Transporter and channel
Click To Hide/Show 5 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Hsp90 co-chaperone Cdc37 (CDC37) CDC37 family Q16543
Exocyst complex component 8 (EXOC8) EXO84 family Q8IYI6
Glutamate receptor ionotropic, NMDA 2C (GRIN2C) Glutamate-gated ion channel family Q14957
Aquaporin-1 (AQP1) MIP/aquaporin (TC 1.A.8) family P29972
Sodium channel modifier 1 (SCNM1) . Q9BWG6
Transcription factor
Click To Hide/Show 15 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Homeobox protein Hox-C8 (HOXC8) Antp homeobox family P31273
Homeobox protein Hox-A1 (HOXA1) Antp homeobox family P49639
Mothers against decapentaplegic homolog 3 (SMAD3) Dwarfin/SMAD family P84022
Zinc finger protein ZIC 1 (ZIC1) GLI C2H2-type zinc-finger protein family Q15915
Zinc finger protein Aiolos (IKZF3) Ikaros C2H2-type zinc-finger protein family Q9UKT9
Zinc finger and BTB domain-containing protein 16 (ZBTB16) Krueppel C2H2-type zinc-finger protein family Q05516
Zinc finger and BTB domain-containing protein 24 (ZBTB24) Krueppel C2H2-type zinc-finger protein family O43167
Zinc finger imprinted 2 (ZIM2) Krueppel C2H2-type zinc-finger protein family Q9NZV7
Zinc finger protein 124 (ZNF124) Krueppel C2H2-type zinc-finger protein family Q15973
Zinc finger protein 417 (ZNF417) Krueppel C2H2-type zinc-finger protein family Q8TAU3
Zinc finger protein 76 (ZNF76) Krueppel C2H2-type zinc-finger protein family P36508
B-cell lymphoma 6 protein (BCL6) . P41182
Transcription factor 19 (TCF19) . Q9Y242
Zinc finger CCCH-type with G patch domain-containing protein (ZGPAT) . Q8N5A5
Zinc finger protein 410 (ZNF410) . Q86VK4
Other
Click To Hide/Show 42 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Protein BEX2 (BEX2) BEX family Q9BXY8
Cilia- and flagella-associated protein 206 (CFAP206) CFAP206 family Q8IYR0
Cyclin-dependent kinase 2-interacting protein (CINP) CINP family Q9BW66
Cyclin-H (CCNH) Cyclin family P51946
Protein FAM90A1 (FAM90A1) FAM90 family Q86YD7
Harmonin-binding protein USHBP1 (USHBP1) MCC family Q8N6Y0
Microfibrillar-associated protein 1 (MFAP1) MFAP1 family P55081
MICOS complex subunit MIC19 (CHCHD3) MICOS complex subunit Mic19 family Q9NX63
Mitotic interactor and substrate of PLK1 (MISP) MISP family Q8IVT2
Nuclear distribution protein nudE-like 1 (NDEL1) NudE family Q9GZM8
Ornithine decarboxylase antizyme 3 (OAZ3) ODC antizyme family Q9UMX2
Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) PI3K p85 subunit family Q92569
Pre-mRNA-splicing factor 18 (PRPF18) PRP18 family Q99633
Protein SSX2 (SSX2; SSX2B) SSX family Q16385
Synaptotagmin-17 (SYT17) Synaptotagmin family Q9BSW7
Tektin-4 (TEKT4) Tektin family Q8WW24
Trafficking protein particle complex subunit 2-like protein (TRAPPC2L) TRAPP small subunits family Q9UL33
Gelsolin (GSN) Villin/gelsolin family P06396
Vacuolar protein sorting-associated protein 28 homolog (VPS28) VPS28 family Q9UK41
BAG family molecular chaperone regulator 3 (BAG3) . O95817
BAG family molecular chaperone regulator 4 (BAG4) . O95429
BTB/POZ domain-containing protein KCTD9 (KCTD9) . Q7L273
Caspase recruitment domain-containing protein 9 (CARD9) . Q9H257
Coiled-coil domain-containing protein 120 (CCDC120) . Q96HB5
Enkurin domain-containing protein 1 (ENKD1) . Q9H0I2
FERM domain-containing protein 6 (FRMD6) . Q96NE9
Fibroblast growth factor receptor substrate 3 (FRS3) . O43559
Four and a half LIM domains protein 2 (FHL2) . Q14192
INO80 complex subunit B (INO80B) . Q9C086
IQ motif and ubiquitin-like domain-containing protein (IQUB) . Q8NA54
Kelch-like protein 38 (KLHL38) . Q2WGJ6
KN motif and ankyrin repeat domain-containing protein 2 (KANK2) . Q63ZY3
MORN repeat-containing protein 3 (MORN3) . Q6PF18
Placental protein 13-like (LGALS14) . Q8TCE9
Protocadherin beta-12 (PCDHB12) . Q9Y5F1
Rhombotin-1 (LMO1) . P25800
Rhombotin-2 (LMO2) . P25791
Sprouty-related, EVH1 domain-containing protein 1 (SPRED1) . Q7Z699
TBC1 domain family member 22B (TBC1D22B) . Q9NU19
TBC1 domain family member 7 (TBC1D7) . Q9P0N9
Telethonin (TCAP) . O15273
Ubiquilin-1 (UBQLN1) . Q9UMX0

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
2 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
3 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
4 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402