Details of the Target

General Information of Target

Target ID LDTP02705
Target Name Probable splicing factor YJU2B (YJU2B)
Gene Name YJU2B
Gene ID 81576
Synonyms
CCDC130; Probable splicing factor YJU2B; Coiled-coil domain-containing protein 130
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MGERKGVNKYYPPDFNPEKHGSLNRYHNSHPLRERARKLSQGILIIRFEMPYNIWCDGCK
NHIGMGVRYNAEKKKVGNYYTTPIYRFRMKCHLCVNYIEMQTDPANCDYVIVSGAQRKEE
RWDMADNEQVLTTEHEKKQKLETDAMFRLEHGEADRSTLKKALPTLSHIQEAQSAWKDDF
ALNSMLRRRFREKKKAIQEEEERDQALQAKASLTIPLVPETEDDRKLAALLKFHTLDSYE
DKQKLKRTEIISRSWFPSAPGSASSSKVSGVLKKLAQSRRTALATSPITVGDLGIVRRRS
RDVPESPQHAADTPKSGEPRVPEEAAQDRPMSPGDCPPETTETPKCSSPRGQEGSRQDKP
LSPAGSSQEAADTPDTRHPCSLGSSLVADYSDSESE
Target Bioclass
Other
Family
CWC16 family
Subcellular location
Nucleus
Function May be involved in mRNA splicing.
Uniprot ID
P13994
Ensemble ID
ENST00000221554.13
HGNC ID
HGNC:28118

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		13.16  LDD0402  [1]
DBIA
 Probe Info  		C56(0.52); C59(0.52)  LDD1093  [2]
AOyne
 Probe Info  		13.70  LDD0443  [3]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 PaTu 8988t C56(0.52); C59(0.52)  LDD1093  [2]
 LDCM0215  AC10 PaTu 8988t C56(0.81); C59(0.81)  LDD1094  [2]
 LDCM0226  AC11 PaTu 8988t C56(0.80); C59(0.80)  LDD1105  [2]
 LDCM0237  AC12 PaTu 8988t C56(0.67); C59(0.67)  LDD1116  [2]
 LDCM0259  AC14 PaTu 8988t C56(0.96); C59(0.96)  LDD1138  [2]
 LDCM0270  AC15 PaTu 8988t C56(0.85); C59(0.85)  LDD1149  [2]
 LDCM0279  AC2 PaTu 8988t C56(0.73); C59(0.73)  LDD1158  [2]
 LDCM0290  AC3 PaTu 8988t C56(0.72); C59(0.72)  LDD1169  [2]
 LDCM0301  AC4 PaTu 8988t C56(0.81); C59(0.81)  LDD1180  [2]
 LDCM0308  AC46 PaTu 8988t C56(0.74); C59(0.74)  LDD1187  [2]
 LDCM0309  AC47 PaTu 8988t C56(0.81); C59(0.81)  LDD1188  [2]
 LDCM0310  AC48 PaTu 8988t C56(0.69); C59(0.69)  LDD1189  [2]
 LDCM0311  AC49 PaTu 8988t C56(0.51); C59(0.51)  LDD1190  [2]
 LDCM0312  AC5 PaTu 8988t C56(0.54); C59(0.54)  LDD1191  [2]
 LDCM0313  AC50 PaTu 8988t C56(0.59); C59(0.59)  LDD1192  [2]
 LDCM0314  AC51 PaTu 8988t C56(0.18); C59(0.18)  LDD1193  [2]
 LDCM0315  AC52 PaTu 8988t C56(0.70); C59(0.70)  LDD1194  [2]
 LDCM0316  AC53 PaTu 8988t C56(0.56); C59(0.56)  LDD1195  [2]
 LDCM0317  AC54 PaTu 8988t C56(0.55); C59(0.55)  LDD1196  [2]
 LDCM0318  AC55 PaTu 8988t C56(0.50); C59(0.50)  LDD1197  [2]
 LDCM0319  AC56 PaTu 8988t C56(0.63); C59(0.63)  LDD1198  [2]
 LDCM0323  AC6 PaTu 8988t C56(0.69); C59(0.69)  LDD1202  [2]
 LDCM0334  AC7 PaTu 8988t C56(0.85); C59(0.85)  LDD1213  [2]
 LDCM0345  AC8 PaTu 8988t C56(0.89); C59(0.89)  LDD1224  [2]
 LDCM0248  AKOS034007472 PaTu 8988t C56(0.80); C59(0.80)  LDD1127  [2]
 LDCM0356  AKOS034007680 PaTu 8988t C56(0.75); C59(0.75)  LDD1235  [2]
 LDCM0275  AKOS034007705 PaTu 8988t C56(0.78); C59(0.78)  LDD1154  [2]
 LDCM0367  CL1 PaTu 8988t C56(0.95); C59(0.95)  LDD1246  [2]
 LDCM0368  CL10 PaTu 8988t C56(0.85); C59(0.85)  LDD1247  [2]
 LDCM0369  CL100 PaTu 8988t C56(0.66); C59(0.66)  LDD1248  [2]
 LDCM0370  CL101 PaTu 8988t C56(0.94); C59(0.94)  LDD1249  [2]
 LDCM0371  CL102 PaTu 8988t C56(0.76); C59(0.76)  LDD1250  [2]
 LDCM0372  CL103 PaTu 8988t C56(0.64); C59(0.64)  LDD1251  [2]
 LDCM0373  CL104 PaTu 8988t C56(0.96); C59(0.96)  LDD1252  [2]
 LDCM0379  CL11 PaTu 8988t C56(1.03); C59(1.03)  LDD1258  [2]
 LDCM0390  CL12 PaTu 8988t C56(0.90); C59(0.90)  LDD1269  [2]
 LDCM0392  CL121 PaTu 8988t C56(0.81); C59(0.81)  LDD1271  [2]
 LDCM0393  CL122 PaTu 8988t C56(0.82); C59(0.82)  LDD1272  [2]
 LDCM0394  CL123 PaTu 8988t C56(0.56); C59(0.56)  LDD1273  [2]
 LDCM0395  CL124 PaTu 8988t C56(0.52); C59(0.52)  LDD1274  [2]
 LDCM0400  CL13 PaTu 8988t C56(0.76); C59(0.76)  LDD1279  [2]
 LDCM0401  CL14 PaTu 8988t C56(0.75); C59(0.75)  LDD1280  [2]
 LDCM0402  CL15 PaTu 8988t C56(0.86); C59(0.86)  LDD1281  [2]
 LDCM0407  CL2 PaTu 8988t C56(0.85); C59(0.85)  LDD1286  [2]
 LDCM0418  CL3 PaTu 8988t C56(0.78); C59(0.78)  LDD1297  [2]
 LDCM0420  CL31 PaTu 8988t C56(0.66); C59(0.66)  LDD1299  [2]
 LDCM0421  CL32 PaTu 8988t C56(0.61); C59(0.61)  LDD1300  [2]
 LDCM0422  CL33 PaTu 8988t C56(0.64); C59(0.64)  LDD1301  [2]
 LDCM0423  CL34 PaTu 8988t C56(0.54); C59(0.54)  LDD1302  [2]
 LDCM0424  CL35 PaTu 8988t C56(0.53); C59(0.53)  LDD1303  [2]
 LDCM0425  CL36 PaTu 8988t C56(0.45); C59(0.45)  LDD1304  [2]
 LDCM0426  CL37 PaTu 8988t C56(0.67); C59(0.67)  LDD1305  [2]
 LDCM0428  CL39 PaTu 8988t C56(0.65); C59(0.65)  LDD1307  [2]
 LDCM0429  CL4 PaTu 8988t C56(0.74); C59(0.74)  LDD1308  [2]
 LDCM0430  CL40 PaTu 8988t C56(0.73); C59(0.73)  LDD1309  [2]
 LDCM0431  CL41 PaTu 8988t C56(0.53); C59(0.53)  LDD1310  [2]
 LDCM0432  CL42 PaTu 8988t C56(0.62); C59(0.62)  LDD1311  [2]
 LDCM0433  CL43 PaTu 8988t C56(0.51); C59(0.51)  LDD1312  [2]
 LDCM0434  CL44 PaTu 8988t C56(0.57); C59(0.57)  LDD1313  [2]
 LDCM0435  CL45 PaTu 8988t C56(0.57); C59(0.57)  LDD1314  [2]
 LDCM0436  CL46 PaTu 8988t C56(0.96); C59(0.96)  LDD1315  [2]
 LDCM0437  CL47 PaTu 8988t C56(0.92); C59(0.92)  LDD1316  [2]
 LDCM0438  CL48 PaTu 8988t C56(0.83); C59(0.83)  LDD1317  [2]
 LDCM0439  CL49 PaTu 8988t C56(0.80); C59(0.80)  LDD1318  [2]
 LDCM0440  CL5 PaTu 8988t C56(0.81); C59(0.81)  LDD1319  [2]
 LDCM0441  CL50 PaTu 8988t C56(0.84); C59(0.84)  LDD1320  [2]
 LDCM0442  CL51 PaTu 8988t C56(1.07); C59(1.07)  LDD1321  [2]
 LDCM0443  CL52 PaTu 8988t C56(0.86); C59(0.86)  LDD1322  [2]
 LDCM0444  CL53 PaTu 8988t C56(0.74); C59(0.74)  LDD1323  [2]
 LDCM0445  CL54 PaTu 8988t C56(0.85); C59(0.85)  LDD1324  [2]
 LDCM0446  CL55 PaTu 8988t C56(0.80); C59(0.80)  LDD1325  [2]
 LDCM0447  CL56 PaTu 8988t C56(0.74); C59(0.74)  LDD1326  [2]
 LDCM0448  CL57 PaTu 8988t C56(0.88); C59(0.88)  LDD1327  [2]
 LDCM0449  CL58 PaTu 8988t C56(0.82); C59(0.82)  LDD1328  [2]
 LDCM0450  CL59 PaTu 8988t C56(0.89); C59(0.89)  LDD1329  [2]
 LDCM0451  CL6 PaTu 8988t C56(0.83); C59(0.83)  LDD1330  [2]
 LDCM0452  CL60 PaTu 8988t C56(0.88); C59(0.88)  LDD1331  [2]
 LDCM0462  CL7 PaTu 8988t C56(0.97); C59(0.97)  LDD1341  [2]
 LDCM0473  CL8 PaTu 8988t C56(0.71); C59(0.71)  LDD1352  [2]
 LDCM0484  CL9 PaTu 8988t C56(0.72); C59(0.72)  LDD1363  [2]
 LDCM0486  CL91 PaTu 8988t C56(0.68); C59(0.68)  LDD1365  [2]
 LDCM0487  CL92 PaTu 8988t C56(0.59); C59(0.59)  LDD1366  [2]
 LDCM0488  CL93 PaTu 8988t C56(0.66); C59(0.66)  LDD1367  [2]
 LDCM0489  CL94 PaTu 8988t C56(0.59); C59(0.59)  LDD1368  [2]
 LDCM0490  CL95 PaTu 8988t C56(0.57); C59(0.57)  LDD1369  [2]
 LDCM0491  CL96 PaTu 8988t C56(0.59); C59(0.59)  LDD1370  [2]
 LDCM0492  CL97 PaTu 8988t C56(0.68); C59(0.68)  LDD1371  [2]
 LDCM0493  CL98 PaTu 8988t C56(0.56); C59(0.56)  LDD1372  [2]
 LDCM0494  CL99 PaTu 8988t C56(0.65); C59(0.65)  LDD1373  [2]
 LDCM0427  Fragment51 PaTu 8988t C56(0.48); C59(0.48)  LDD1306  [2]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Polyribonucleotide 5'-hydroxyl-kinase Clp1 (CLP1) Clp1 family Q92989
Testis-specific serine/threonine-protein kinase 3 (TSSK3) CAMK Ser/Thr protein kinase family Q96PN8
Transcription factor
Click To Hide/Show 13 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Zinc finger and SCAN domain-containing protein 23 (ZSCAN23) Krueppel C2H2-type zinc-finger protein family Q3MJ62
Zinc finger protein 165 (ZNF165) Krueppel C2H2-type zinc-finger protein family P49910
Zinc finger protein 17 (ZNF17) Krueppel C2H2-type zinc-finger protein family P17021
Zinc finger protein 24 (ZNF24) Krueppel C2H2-type zinc-finger protein family P17028
Zinc finger protein 3 (ZNF3) Krueppel C2H2-type zinc-finger protein family P17036
Zinc finger protein 3 homolog (ZFP3) Krueppel C2H2-type zinc-finger protein family Q96NJ6
Zinc finger protein 329 (ZNF329) Krueppel C2H2-type zinc-finger protein family Q86UD4
Zinc finger protein 35 (ZNF35) Krueppel C2H2-type zinc-finger protein family P13682
Zinc finger protein 572 (ZNF572) Krueppel C2H2-type zinc-finger protein family Q7Z3I7
Zinc finger protein 629 (ZNF629) Krueppel C2H2-type zinc-finger protein family Q9UEG4
Zinc finger protein 774 (ZNF774) Krueppel C2H2-type zinc-finger protein family Q6NX45
Zinc finger protein 79 (ZNF79) Krueppel C2H2-type zinc-finger protein family Q15937
Zinc finger protein 835 (ZNF835) Krueppel C2H2-type zinc-finger protein family Q9Y2P0
Other
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 (SMARCD1) SMARCD family Q96GM5
EF-hand domain-containing protein 1 (EFHC1) . Q5JVL4
Heat shock factor 2-binding protein (HSF2BP) . O75031

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.