Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C190  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10215  Carboxymethylenebutenolidase homolog (CMBL) 6.6
 LDTP02342  Dihydropteridine reductase (QDPR) 5.9
 LDTP11321  Acetyl-CoA acetyltransferase, cytosolic (ACAT2) 5.4
Transporter and channel
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP04237  Protein ERGIC-53 (LMAN1) 6.5
 LDTP07885  Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) 5.0
Other
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP12025  UPF0488 protein C8orf33 (C8orf33) 7.9
 LDTP04926  Large ribosomal subunit protein eL43 (RPL37A) 5.7

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587