Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name photo_BS  Probe Info 
Probe concentration 10 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
SILAC
Competitor Name Bromosprine  Competitor Info 
Competitor Concentration 10 mM
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Osteosarcoma [ICD-11:2B51]
Model Name Human osteosarcoma cells (U2OS)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP16070  Epimerase family protein SDR39U1 (SDR39U1) 2.1
 LDTP15370  Pseudouridylate synthase RPUSD2 (RPUSD2) 1.9
Other
Click to Show/Hide to Show 4 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03322  Bromodomain-containing protein 2 (BRD2) 2.7
 LDTP06304  Bromodomain-containing protein 3 (BRD3) 2.7
 LDTP12369  Bromodomain-containing protein 7 (BRD7) 2.4
 LDTP01074  Bromodomain-containing protein 4 (BRD4) 2.4

References

1 Chemical Proteomic Profiling of Bromodomains Enables the Wide-Spectrum Evaluation of Bromodomain Inhibitors in Living Cells. J Am Chem Soc. 2019 Jul 24;141(29):11497-11505. doi: 10.1021/jacs.9b02738. Epub 2019 Jul 9.