General Information of Experiment

Probe Name Cep-alkyne  Probe Info 
Probe concentration 10 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
LFQ
Competitor Name Cepafungin 1  Competitor Info 
Competitor Concentration 100 nM
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Plasma cell myeloma [ICD-11:2A83]
Model Name Human plasma cell myeloma cells (RPMI-8226)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 5 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03419  Proteasome subunit beta type-5 (PSMB5) 6.6
 LDTP03893  Proteasome subunit beta type-10 (PSMB10) 3.3
 LDTP03413  Proteasome subunit alpha type-5 (PSMA5) 2.4
 LDTP03060  Proteasome subunit beta type-1 (PSMB1) 2.1
 LDTP04285  Proteasome subunit beta type-2 (PSMB2) 2.1

References

1 Concise Chemoenzymatic Total Synthesis and Identification of Cellular Targets of Cepafungin I. Cell Chem Biol. 2020 Oct 15;27(10):1318-1326.e18. doi: 10.1016/j.chembiol.2020.07.012. Epub 2020 Aug 6.