Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name Propranolol-CA-4PAP  Probe Info 
Probe concentration 1 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
LFQ
Competitor Name Propranolol  Competitor Info 
Competitor Concentration 20 uM
In Vivo Experiment Model Model Type Cell lysate
Derived Tissue Peripheral blood
Disease Model Chronic myeloid leukemia [ICD-11:2A20]
Model Name Human chronic myeloid leukemia cell lysate (K562)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP15988  Probable serine carboxypeptidase CPVL (CPVL) 4.9
 LDTP06200  Delta(14)-sterol reductase LBR (LBR) 4.1
 LDTP04388  Palmitoyl-protein thioesterase 1 (PPT1) 4.0
Transporter and channel
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP11615  Protein tweety homolog 3 (TTYH3) 15.0
 LDTP06034  Lysosome membrane protein 2 (SCARB2) 4.6
 LDTP09547  Scavenger receptor class B member 1 (SCARB1) 4.2

References

1 Streamlined Target Deconvolution Approach Utilizing a Single Photoreactive Chloroalkane Capture Tag. ACS Chem Biol. 2021 Feb 19;16(2):404-413. doi: 10.1021/acschembio.0c00987. Epub 2021 Feb 5.