Details of the Competitor

General Information of Competitor

Competitor ID
LDCM0115
Competitor Name
Minimalist
Synonyms
1450754-41-2; 2-(3-but-3-ynyl-3H-diazirin-3-yl)-ethanol; 3-(3-Butyn-1-yl)-3H-diazirine-3-ethanol; 2-(3-but-3-ynyldiazirin-3-yl)ethanol; MFCD29918290; 2-(3-(but-3-yn-1-yl)-3H-diazirin-3-yl)ethan-1-ol; 3H-Diazirine-3-ethanol, 3-(3-butyn-1-yl)-; 2-[3-(but-3-yn-1-yl)-3H-diazirin-3-yl]ethan-1-ol; 3-(3-Butynyl)-3H-diazirine-3-ethanol; SCHEMBL20680946; DTXSID801278943; AKOS026720521; DS-19296; SY106324; DB-121580; CS-0106038; 2-(3-But-3-ynyl-3H-diazirin-3-yl)ethanol; EN300-227135; N11436; A920636; 2-[3-(BUT-3-YN-1-YL)DIAZIRIN-3-YL]ETHANOL; 2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol, >=95%; F2197-0240; Z1898593365
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 138.17
Lipid-water partition coefficient (xlogp) 0.8
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C7H10N2O
IUPAC Name
2-(3-but-3-ynyldiazirin-3-yl)ethanol
Canonical SMILES
C#CCCC1(N=N1)CCO
InChI
InChI=1S/C7H10N2O/c1-2-3-4-7(5-6-10)8-9-7/h1,10H,3-6H2
InChIKey
NMIZSJAOOMXKDJ-UHFFFAOYSA-N

The Competitor Interaction Atlas

Probe(s) Related This Competitor

PAL-AfBPP Probe
Click To Hide/Show 1 Probe Related to This Competitor
Probe Name Structure Concentration Cell-system Ref
pLen
 Probe Info  		50 uM Human normal cells (HEK-293T) [1]

Target(s) List of this Competitor

1 Enzyme Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 2.04  LDD0256 
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3 Other Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Eukaryotic translation initiation factor 1A, X-chromosomal (EIF1AX) LDTP04129 2.23  LDD0256 
Eukaryotic translation initiation factor 1A, Y-chromosomal (EIF1AY) LDTP14429 2.23  LDD0256 
Eukaryotic translation initiation factor 3 subunit I (EIF3I) LDTP05834 3.95  LDD0256 
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Full Information of The Labelling Profiles of This Competitor

Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 50 uM
Quantitative Method LFQ
Competitor Name Minimalist
Competitor Concentration 150 uM
In Vitro Experiment Model Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Interaction Atlas ID  LDD0256  Download The Altas

References

1 Development of Photolenalidomide for Cellular Target Identification. J Am Chem Soc. 2022 Jan 12;144(1):606-614. doi: 10.1021/jacs.1c11920. Epub 2022 Jan 3.