Details of the Target

General Information of Target

Target ID LDTP19855
Target Name Protein EOLA2 (EOLA2)
Gene Name EOLA2
Gene ID 541578
Synonyms
CXorf40B; Protein EOLA2; Protein CXorf40B
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MVALENPECGPEAAEGTPGGRRLLPLPSCLPALASSQVKRLSASRRKQHFINQAVRNSDL
VPKAKGRKSLQRLENTQYLLTLLETDGGLPGLEDGDLAPPASPGIFAEACNNATYVEVWN
DFMNRSGEEQERVLRYLEDEGRSKARRRGPGRGEDRRREDPAYTPRECFQRISRRLRAVL
KRSRIPMETLETWEERLLRFFSVSPQAVYTAMLDNSFERLLLHAVCQYMDLISASADLEG
KRQMKVSNRHLDFLPPGLLLSAYLEQHS
Target Bioclass
Other
Family
EOLA family
Uniprot ID
Q96DE9
Ensemble ID
ENST00000355203.6
HGNC ID
HGNC:17402

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C5(1.03)  LDD1514  [1]
IA-alkyne
 Probe Info  		N.A.  LDD0165  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0284  AC24 HEK-293T C5(0.86)  LDD1523  [1]
 LDCM0293  AC32 HEK-293T C5(0.96)  LDD1532  [1]
 LDCM0302  AC40 HEK-293T C5(1.06)  LDD1541  [1]
 LDCM0310  AC48 HEK-293T C5(1.01)  LDD1549  [1]
 LDCM0319  AC56 HEK-293T C5(1.00)  LDD1558  [1]
 LDCM0328  AC64 HEK-293T C5(1.01)  LDD1567  [1]
 LDCM0345  AC8 HEK-293T C5(1.22)  LDD1569  [1]
 LDCM0275  AKOS034007705 HEK-293T C5(1.03)  LDD1514  [1]
 LDCM0369  CL100 HEK-293T C5(1.23)  LDD1573  [1]
 LDCM0373  CL104 HEK-293T C5(0.99)  LDD1577  [1]
 LDCM0377  CL108 HEK-293T C5(1.02)  LDD1581  [1]
 LDCM0382  CL112 HEK-293T C5(1.11)  LDD1586  [1]
 LDCM0386  CL116 HEK-293T C5(1.01)  LDD1590  [1]
 LDCM0390  CL12 HEK-293T C5(1.41)  LDD1594  [1]
 LDCM0391  CL120 HEK-293T C5(0.97)  LDD1595  [1]
 LDCM0395  CL124 HEK-293T C5(0.94)  LDD1599  [1]
 LDCM0399  CL128 HEK-293T C5(0.89)  LDD1603  [1]
 LDCM0403  CL16 HEK-293T C5(0.88)  LDD1607  [1]
 LDCM0412  CL24 HEK-293T C5(0.89)  LDD1616  [1]
 LDCM0416  CL28 HEK-293T C5(1.00)  LDD1620  [1]
 LDCM0425  CL36 HEK-293T C5(1.13)  LDD1629  [1]
 LDCM0429  CL4 HEK-293T C5(1.13)  LDD1633  [1]
 LDCM0430  CL40 HEK-293T C5(0.96)  LDD1634  [1]
 LDCM0438  CL48 HEK-293T C5(1.04)  LDD1642  [1]
 LDCM0443  CL52 HEK-293T C5(1.14)  LDD1646  [1]
 LDCM0452  CL60 HEK-293T C5(0.94)  LDD1655  [1]
 LDCM0456  CL64 HEK-293T C5(1.42)  LDD1659  [1]
 LDCM0465  CL72 HEK-293T C5(0.94)  LDD1668  [1]
 LDCM0469  CL76 HEK-293T C5(0.92)  LDD1672  [1]
 LDCM0478  CL84 HEK-293T C5(1.00)  LDD1681  [1]
 LDCM0482  CL88 HEK-293T C5(1.08)  LDD1685  [1]
 LDCM0491  CL96 HEK-293T C5(1.22)  LDD1694  [1]

References

1 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
2 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060