Details of the Target

General Information of Target

Target ID LDTP19326
Target Name Putative ribosomal protein eL39-like 5 (RPL39P5)
Gene Name RPL39P5
Synonyms
Putative ribosomal protein eL39-like 5; 60S ribosomal protein L39 pseudogene 5; Putative 60S ribosomal protein L39-like 5
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MWILSNLMGTSEEGNLLSTVSPTVKALFGKTRVSPIFPFSPRSPFQPLIPRTPGSPWGPV
GPASPLGPGFPIGPMGPGKPVGPKGPMLPLGPSGPVGPTSPLFPFCP
Target Bioclass
Other
Family
Eukaryotic ribosomal protein eL39 family
Uniprot ID
Q59GN2
HGNC ID
HGNC:26015

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
P1
 Probe Info  		1.77  LDD0448  [1]
AF-2
 Probe Info  		2.29  LDD0422  [2]
Ox-W18
 Probe Info  		N.A.  LDD2175  [3]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0166  Afatinib A431 2.29  LDD0422  [2]

References

1 Comparison of Different Competitive Proteome Profiling Approaches in Target Identification of Covalent Inhibitors. Chembiochem. 2022 Dec 16;23(24):e202200389. doi: 10.1002/cbic.202200389. Epub 2022 Nov 22.
2 Minimalist linkers suitable for irreversible inhibitors in simultaneous proteome profiling, live-cell imaging and drug screening. Chem Commun (Camb). 2019 Jan 15;55(6):834-837. doi: 10.1039/c8cc08685k.
3 Oxidative cyclization reagents reveal tryptophan cation- interactions. Nature. 2024 Mar;627(8004):680-687. doi: 10.1038/s41586-024-07140-6. Epub 2024 Mar 6.
Mass spectrometry data entry: PXD001377 , PXD005252