Details of the Target

General Information of Target

Target ID LDTP19096
Target Name Zinc finger protein 865 (ZNF865)
Gene Name ZNF865
Gene ID 100507290
Synonyms
Zinc finger protein 865
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MTTRGFSCLLLLIREIDLSAKRRI
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
P0CJ78
Ensemble ID
ENST00000568956.2
HGNC ID
HGNC:38705

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		C822(13.28)  LDD0315  [1]
DBIA
 Probe Info  		C409(0.79); C412(0.79)  LDD0533  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0216  AC100 HCT 116 C409(0.79); C412(0.79)  LDD0533  [2]
 LDCM0217  AC101 HCT 116 C409(0.89); C412(0.89)  LDD0534  [2]
 LDCM0218  AC102 HCT 116 C409(0.87); C412(0.87)  LDD0535  [2]
 LDCM0219  AC103 HCT 116 C409(0.93); C412(0.93)  LDD0536  [2]
 LDCM0220  AC104 HCT 116 C409(0.87); C412(0.87)  LDD0537  [2]
 LDCM0221  AC105 HCT 116 C409(0.87); C412(0.87)  LDD0538  [2]
 LDCM0222  AC106 HCT 116 C409(1.00); C412(1.00)  LDD0539  [2]
 LDCM0223  AC107 HCT 116 C409(0.47); C412(1.06)  LDD0540  [2]
 LDCM0224  AC108 HCT 116 C409(0.57); C412(0.67)  LDD0541  [2]
 LDCM0225  AC109 HCT 116 C409(0.55); C412(0.70)  LDD0542  [2]
 LDCM0227  AC110 HCT 116 C409(0.49); C412(0.64)  LDD0544  [2]
 LDCM0228  AC111 HCT 116 C409(0.53); C412(0.70)  LDD0545  [2]
 LDCM0229  AC112 HCT 116 C409(0.48); C412(0.85)  LDD0546  [2]
 LDCM0263  AC143 HCT 116 C409(1.20); C412(1.20)  LDD0580  [2]
 LDCM0264  AC144 HCT 116 C412(1.03); C409(1.19)  LDD0581  [2]
 LDCM0265  AC145 HCT 116 C412(0.94); C409(1.22)  LDD0582  [2]
 LDCM0266  AC146 HCT 116 C412(0.90); C409(1.56)  LDD0583  [2]
 LDCM0267  AC147 HCT 116 C412(0.99); C409(1.05)  LDD0584  [2]
 LDCM0268  AC148 HCT 116 C412(0.95); C409(2.50)  LDD0585  [2]
 LDCM0269  AC149 HCT 116 C412(0.84); C409(2.12)  LDD0586  [2]
 LDCM0271  AC150 HCT 116 C412(0.91); C409(1.36)  LDD0588  [2]
 LDCM0272  AC151 HCT 116 C412(1.04); C409(1.41)  LDD0589  [2]
 LDCM0273  AC152 HCT 116 C412(0.98); C409(1.38)  LDD0590  [2]
 LDCM0274  AC153 HCT 116 C412(0.87); C409(1.80)  LDD0591  [2]
 LDCM0621  AC154 HCT 116 C409(1.37); C412(0.87)  LDD2158  [2]
 LDCM0622  AC155 HCT 116 C409(1.44); C412(0.97)  LDD2159  [2]
 LDCM0623  AC156 HCT 116 C409(1.23); C412(0.83)  LDD2160  [2]
 LDCM0624  AC157 HCT 116 C409(1.51); C412(1.03)  LDD2161  [2]
 LDCM0296  AC35 HCT 116 C409(0.99); C412(0.99)  LDD0613  [2]
 LDCM0297  AC36 HCT 116 C409(0.89); C412(0.89)  LDD0614  [2]
 LDCM0298  AC37 HCT 116 C409(0.75); C412(0.75)  LDD0615  [2]
 LDCM0299  AC38 HCT 116 C409(1.06); C412(1.06)  LDD0616  [2]
 LDCM0300  AC39 HCT 116 C409(0.98); C412(0.98)  LDD0617  [2]
 LDCM0302  AC40 HCT 116 C409(0.94); C412(0.94)  LDD0619  [2]
 LDCM0303  AC41 HCT 116 C409(1.13); C412(1.13)  LDD0620  [2]
 LDCM0304  AC42 HCT 116 C409(0.94); C412(0.94)  LDD0621  [2]
 LDCM0305  AC43 HCT 116 C409(1.13); C412(1.13)  LDD0622  [2]
 LDCM0306  AC44 HCT 116 C409(0.79); C412(0.79)  LDD0623  [2]
 LDCM0307  AC45 HCT 116 C409(0.94); C412(0.94)  LDD0624  [2]
 LDCM0332  AC68 HCT 116 C409(1.26); C412(1.26)  LDD0649  [2]
 LDCM0333  AC69 HCT 116 C409(1.27); C412(1.27)  LDD0650  [2]
 LDCM0335  AC70 HCT 116 C409(0.98); C412(0.98)  LDD0652  [2]
 LDCM0336  AC71 HCT 116 C409(1.24); C412(1.24)  LDD0653  [2]
 LDCM0337  AC72 HCT 116 C409(1.10); C412(1.10)  LDD0654  [2]
 LDCM0338  AC73 HCT 116 C409(1.32); C412(1.32)  LDD0655  [2]
 LDCM0339  AC74 HCT 116 C409(1.38); C412(1.38)  LDD0656  [2]
 LDCM0340  AC75 HCT 116 C409(1.29); C412(1.29)  LDD0657  [2]
 LDCM0341  AC76 HCT 116 C409(1.16); C412(1.16)  LDD0658  [2]
 LDCM0342  AC77 HCT 116 C409(1.73); C412(1.73)  LDD0659  [2]
 LDCM0343  AC78 HCT 116 C409(1.09); C412(1.09)  LDD0660  [2]
 LDCM0344  AC79 HCT 116 C409(1.13); C412(1.13)  LDD0661  [2]
 LDCM0346  AC80 HCT 116 C409(1.14); C412(1.14)  LDD0663  [2]
 LDCM0347  AC81 HCT 116 C409(1.13); C412(1.13)  LDD0664  [2]
 LDCM0348  AC82 HCT 116 C409(1.15); C412(1.15)  LDD0665  [2]
 LDCM0349  AC83 HCT 116 C409(1.13); C412(1.13)  LDD0666  [2]
 LDCM0350  AC84 HCT 116 C409(1.00); C412(1.00)  LDD0667  [2]
 LDCM0351  AC85 HCT 116 C409(1.28); C412(1.28)  LDD0668  [2]
 LDCM0352  AC86 HCT 116 C409(1.42); C412(1.42)  LDD0669  [2]
 LDCM0353  AC87 HCT 116 C409(1.25); C412(1.25)  LDD0670  [2]
 LDCM0354  AC88 HCT 116 C409(1.16); C412(1.16)  LDD0671  [2]
 LDCM0355  AC89 HCT 116 C409(1.20); C412(1.20)  LDD0672  [2]
 LDCM0357  AC90 HCT 116 C409(1.38); C412(1.38)  LDD0674  [2]
 LDCM0358  AC91 HCT 116 C409(1.20); C412(1.20)  LDD0675  [2]
 LDCM0359  AC92 HCT 116 C409(1.20); C412(1.20)  LDD0676  [2]
 LDCM0360  AC93 HCT 116 C409(0.99); C412(0.99)  LDD0677  [2]
 LDCM0361  AC94 HCT 116 C409(0.76); C412(0.76)  LDD0678  [2]
 LDCM0362  AC95 HCT 116 C409(1.31); C412(1.31)  LDD0679  [2]
 LDCM0363  AC96 HCT 116 C409(0.81); C412(0.81)  LDD0680  [2]
 LDCM0364  AC97 HCT 116 C409(1.26); C412(1.26)  LDD0681  [2]
 LDCM0365  AC98 HCT 116 C409(0.92); C412(0.92)  LDD0682  [2]
 LDCM0366  AC99 HCT 116 C409(0.77); C412(0.77)  LDD0683  [2]
 LDCM0387  CL117 HCT 116 C409(1.09); C412(1.09)  LDD0704  [2]
 LDCM0388  CL118 HCT 116 C409(1.02); C412(1.02)  LDD0705  [2]
 LDCM0389  CL119 HCT 116 C409(1.06); C412(1.06)  LDD0706  [2]
 LDCM0391  CL120 HCT 116 C409(0.96); C412(0.96)  LDD0708  [2]
 LDCM0453  CL61 HCT 116 C409(1.09); C412(1.09)  LDD0770  [2]
 LDCM0454  CL62 HCT 116 C409(0.98); C412(0.98)  LDD0771  [2]
 LDCM0455  CL63 HCT 116 C409(1.02); C412(1.02)  LDD0772  [2]
 LDCM0456  CL64 HCT 116 C409(1.23); C412(1.23)  LDD0773  [2]
 LDCM0457  CL65 HCT 116 C409(1.09); C412(1.09)  LDD0774  [2]
 LDCM0458  CL66 HCT 116 C409(1.44); C412(1.44)  LDD0775  [2]
 LDCM0459  CL67 HCT 116 C409(1.32); C412(1.32)  LDD0776  [2]
 LDCM0460  CL68 HCT 116 C409(1.09); C412(1.09)  LDD0777  [2]
 LDCM0461  CL69 HCT 116 C409(1.00); C412(1.00)  LDD0778  [2]
 LDCM0463  CL70 HCT 116 C409(1.18); C412(1.18)  LDD0780  [2]
 LDCM0464  CL71 HCT 116 C409(1.03); C412(1.03)  LDD0781  [2]
 LDCM0465  CL72 HCT 116 C409(1.05); C412(1.05)  LDD0782  [2]
 LDCM0466  CL73 HCT 116 C409(1.05); C412(1.05)  LDD0783  [2]
 LDCM0467  CL74 HCT 116 C409(0.94); C412(0.94)  LDD0784  [2]
 LDCM0468  Fragment33 HCT 116 C409(0.97); C412(0.97)  LDD0785  [2]
 LDCM0022  KB02 A2780 C869(1.46)  LDD2254  [3]
 LDCM0023  KB03 Jurkat C822(13.28)  LDD0315  [1]
 LDCM0024  KB05 A2780 C869(1.24)  LDD3088  [3]

References

1 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840