Details of the Target

General Information of Target

Target ID LDTP18993
Target Name Transmembrane protein 178B (TMEM178B)
Gene Name TMEM178B
Gene ID 100507421
Synonyms
Transmembrane protein 178B
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MLSKGRSPRRKQVQTQRKAALVLSVTPMVPVGSVWLAMSSVLSAFMRELPGWFLFFGVFL
PVTLLLLLLIAYFRIKLIEVNEELSQNCDRQHNPKDGSSLYQRMKWT
Target Bioclass
Other
Family
TMEM178 family
Subcellular location
Membrane
Uniprot ID
H3BS89
Ensemble ID
ENST00000565468.6
HGNC ID
HGNC:44112

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C294(0.93)  LDD1492  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0259  AC14 HEK-293T C294(1.07)  LDD1512  [1]
 LDCM0281  AC21 HEK-293T C294(1.12)  LDD1520  [1]
 LDCM0282  AC22 HEK-293T C294(0.93)  LDD1521  [1]
 LDCM0284  AC24 HEK-293T C294(1.09)  LDD1523  [1]
 LDCM0289  AC29 HEK-293T C294(0.85)  LDD1528  [1]
 LDCM0291  AC30 HEK-293T C294(1.08)  LDD1530  [1]
 LDCM0293  AC32 HEK-293T C294(0.89)  LDD1532  [1]
 LDCM0298  AC37 HEK-293T C294(0.89)  LDD1537  [1]
 LDCM0299  AC38 HEK-293T C294(1.04)  LDD1538  [1]
 LDCM0302  AC40 HEK-293T C294(1.01)  LDD1541  [1]
 LDCM0307  AC45 HEK-293T C294(1.00)  LDD1546  [1]
 LDCM0308  AC46 HEK-293T C294(1.04)  LDD1547  [1]
 LDCM0310  AC48 HEK-293T C294(1.12)  LDD1549  [1]
 LDCM0312  AC5 HEK-293T C294(0.74)  LDD1551  [1]
 LDCM0316  AC53 HEK-293T C294(1.08)  LDD1555  [1]
 LDCM0317  AC54 HEK-293T C294(1.04)  LDD1556  [1]
 LDCM0319  AC56 HEK-293T C294(0.95)  LDD1558  [1]
 LDCM0323  AC6 HEK-293T C294(0.94)  LDD1562  [1]
 LDCM0325  AC61 HEK-293T C294(0.91)  LDD1564  [1]
 LDCM0326  AC62 HEK-293T C294(1.11)  LDD1565  [1]
 LDCM0328  AC64 HEK-293T C294(1.00)  LDD1567  [1]
 LDCM0345  AC8 HEK-293T C294(0.98)  LDD1569  [1]
 LDCM0248  AKOS034007472 HEK-293T C294(1.02)  LDD1511  [1]
 LDCM0275  AKOS034007705 HEK-293T C294(1.06)  LDD1514  [1]
 LDCM0368  CL10 HEK-293T C294(0.81)  LDD1572  [1]
 LDCM0390  CL12 HEK-293T C294(0.98)  LDD1594  [1]
 LDCM0409  CL21 HEK-293T C294(0.75)  LDD1613  [1]
 LDCM0410  CL22 HEK-293T C294(0.93)  LDD1614  [1]
 LDCM0412  CL24 HEK-293T C294(1.02)  LDD1616  [1]
 LDCM0422  CL33 HEK-293T C294(0.89)  LDD1626  [1]
 LDCM0423  CL34 HEK-293T C294(0.87)  LDD1627  [1]
 LDCM0425  CL36 HEK-293T C294(0.86)  LDD1629  [1]
 LDCM0435  CL45 HEK-293T C294(0.90)  LDD1639  [1]
 LDCM0436  CL46 HEK-293T C294(0.89)  LDD1640  [1]
 LDCM0438  CL48 HEK-293T C294(0.87)  LDD1642  [1]
 LDCM0448  CL57 HEK-293T C294(0.91)  LDD1651  [1]
 LDCM0449  CL58 HEK-293T C294(0.80)  LDD1652  [1]
 LDCM0452  CL60 HEK-293T C294(1.11)  LDD1655  [1]
 LDCM0461  CL69 HEK-293T C294(0.91)  LDD1664  [1]
 LDCM0463  CL70 HEK-293T C294(0.97)  LDD1666  [1]
 LDCM0465  CL72 HEK-293T C294(0.90)  LDD1668  [1]
 LDCM0475  CL81 HEK-293T C294(0.94)  LDD1678  [1]
 LDCM0476  CL82 HEK-293T C294(0.88)  LDD1679  [1]
 LDCM0478  CL84 HEK-293T C294(0.87)  LDD1681  [1]
 LDCM0484  CL9 HEK-293T C294(0.83)  LDD1687  [1]
 LDCM0488  CL93 HEK-293T C294(0.76)  LDD1691  [1]
 LDCM0489  CL94 HEK-293T C294(1.02)  LDD1692  [1]
 LDCM0491  CL96 HEK-293T C294(0.96)  LDD1694  [1]
 LDCM0022  KB02 HEK-293T C294(0.93)  LDD1492  [1]
 LDCM0023  KB03 HEK-293T C294(0.93)  LDD1497  [1]
 LDCM0024  KB05 HEK-293T C294(0.89)  LDD1502  [1]

References

1 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402