Details of the Target

General Information of Target

Target ID LDTP18521
Target Name Zinc finger protein 70 (ZNF70)
Gene Name ZNF70
Gene ID 7621
Synonyms
Zinc finger protein 70; Zinc finger protein N27C7-1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAEDKTKPSELDQGKYDADDNVKIICLGDSAVGKSKLMERFLMDGFQPQQLSTYALTLYK
HTATVDGKTILVDFWDTAGQERFQSMHASYYHKAHACIMVFDIQRKVTYRNLSTWYTELR
EFRPEIPCIVVANKIDDINVTQKSFNFAKKFSLPLYFVSAADGTNVVKLFNDAIRLAVSY
KQNSQDFMDEIFQELENFSLEQEEEDVPDQEQSSSIETPSEEVASPHS
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
Q9UC06
Ensemble ID
ENST00000341976.5
HGNC ID
HGNC:13140

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C374(1.02)  LDD1492  [1]
HHS-465
 Probe Info  		K334(0.00); K337(0.00); Y336(0.00)  LDD2240  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0226  AC11 HEK-293T C374(1.06)  LDD1509  [1]
 LDCM0259  AC14 HEK-293T C374(1.19)  LDD1512  [1]
 LDCM0278  AC19 HEK-293T C374(1.33)  LDD1517  [1]
 LDCM0282  AC22 HEK-293T C374(1.15)  LDD1521  [1]
 LDCM0284  AC24 HEK-293T C374(1.03)  LDD1523  [1]
 LDCM0287  AC27 HEK-293T C374(1.07)  LDD1526  [1]
 LDCM0290  AC3 HEK-293T C374(0.99)  LDD1529  [1]
 LDCM0291  AC30 HEK-293T C374(1.01)  LDD1530  [1]
 LDCM0293  AC32 HEK-293T C374(0.94)  LDD1532  [1]
 LDCM0296  AC35 HEK-293T C374(1.06)  LDD1535  [1]
 LDCM0299  AC38 HEK-293T C374(1.09)  LDD1538  [1]
 LDCM0302  AC40 HEK-293T C374(1.20)  LDD1541  [1]
 LDCM0305  AC43 HEK-293T C374(1.05)  LDD1544  [1]
 LDCM0308  AC46 HEK-293T C374(1.06)  LDD1547  [1]
 LDCM0310  AC48 HEK-293T C374(1.07)  LDD1549  [1]
 LDCM0314  AC51 HEK-293T C374(1.08)  LDD1553  [1]
 LDCM0317  AC54 HEK-293T C374(1.25)  LDD1556  [1]
 LDCM0319  AC56 HEK-293T C374(1.03)  LDD1558  [1]
 LDCM0322  AC59 HEK-293T C374(0.98)  LDD1561  [1]
 LDCM0323  AC6 HEK-293T C374(1.00)  LDD1562  [1]
 LDCM0326  AC62 HEK-293T C374(1.15)  LDD1565  [1]
 LDCM0328  AC64 HEK-293T C374(1.07)  LDD1567  [1]
 LDCM0345  AC8 HEK-293T C374(1.14)  LDD1569  [1]
 LDCM0275  AKOS034007705 HEK-293T C374(1.08)  LDD1514  [1]
 LDCM0367  CL1 HEK-293T C374(0.98)  LDD1571  [1]
 LDCM0368  CL10 HEK-293T C374(1.22)  LDD1572  [1]
 LDCM0370  CL101 HEK-293T C374(1.09)  LDD1574  [1]
 LDCM0374  CL105 HEK-293T C374(1.01)  LDD1578  [1]
 LDCM0378  CL109 HEK-293T C374(0.97)  LDD1582  [1]
 LDCM0383  CL113 HEK-293T C374(1.02)  LDD1587  [1]
 LDCM0387  CL117 HEK-293T C374(1.15)  LDD1591  [1]
 LDCM0390  CL12 HEK-293T C374(0.85)  LDD1594  [1]
 LDCM0392  CL121 HEK-293T C374(0.98)  LDD1596  [1]
 LDCM0396  CL125 HEK-293T C374(0.86)  LDD1600  [1]
 LDCM0400  CL13 HEK-293T C374(1.08)  LDD1604  [1]
 LDCM0406  CL19 HEK-293T C374(1.07)  LDD1610  [1]
 LDCM0410  CL22 HEK-293T C374(1.15)  LDD1614  [1]
 LDCM0412  CL24 HEK-293T C374(1.00)  LDD1616  [1]
 LDCM0413  CL25 HEK-293T C374(0.99)  LDD1617  [1]
 LDCM0420  CL31 HEK-293T C374(1.00)  LDD1624  [1]
 LDCM0423  CL34 HEK-293T C374(1.04)  LDD1627  [1]
 LDCM0425  CL36 HEK-293T C374(0.94)  LDD1629  [1]
 LDCM0426  CL37 HEK-293T C374(0.85)  LDD1630  [1]
 LDCM0433  CL43 HEK-293T C374(0.88)  LDD1637  [1]
 LDCM0436  CL46 HEK-293T C374(1.25)  LDD1640  [1]
 LDCM0438  CL48 HEK-293T C374(0.89)  LDD1642  [1]
 LDCM0439  CL49 HEK-293T C374(0.96)  LDD1643  [1]
 LDCM0446  CL55 HEK-293T C374(0.96)  LDD1649  [1]
 LDCM0449  CL58 HEK-293T C374(1.35)  LDD1652  [1]
 LDCM0452  CL60 HEK-293T C374(1.07)  LDD1655  [1]
 LDCM0453  CL61 HEK-293T C374(1.05)  LDD1656  [1]
 LDCM0459  CL67 HEK-293T C374(0.91)  LDD1662  [1]
 LDCM0462  CL7 HEK-293T C374(0.96)  LDD1665  [1]
 LDCM0463  CL70 HEK-293T C374(1.24)  LDD1666  [1]
 LDCM0465  CL72 HEK-293T C374(0.94)  LDD1668  [1]
 LDCM0466  CL73 HEK-293T C374(0.99)  LDD1669  [1]
 LDCM0472  CL79 HEK-293T C374(1.06)  LDD1675  [1]
 LDCM0476  CL82 HEK-293T C374(1.22)  LDD1679  [1]
 LDCM0478  CL84 HEK-293T C374(1.01)  LDD1681  [1]
 LDCM0479  CL85 HEK-293T C374(0.90)  LDD1682  [1]
 LDCM0486  CL91 HEK-293T C374(0.91)  LDD1689  [1]
 LDCM0489  CL94 HEK-293T C374(1.11)  LDD1692  [1]
 LDCM0491  CL96 HEK-293T C374(0.79)  LDD1694  [1]
 LDCM0492  CL97 HEK-293T C374(0.87)  LDD1695  [1]
 LDCM0022  KB02 HEK-293T C374(1.02)  LDD1492  [1]
 LDCM0023  KB03 HEK-293T C374(1.02)  LDD1497  [1]
 LDCM0024  KB05 HEK-293T C374(0.97)  LDD1502  [1]

References

1 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
2 Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation. Cell Chem Biol. 2022 Dec 15;29(12):1709-1720.e7. doi: 10.1016/j.chembiol.2022.11.008. Epub 2022 Dec 6.
Mass spectrometry data entry: PXD038010