Details of the Target

General Information of Target

Target ID LDTP17674
Target Name Zinc finger protein 82 homolog (ZFP82)
Gene Name ZFP82
Gene ID 284406
Synonyms
KIAA1948; ZNF545; Zinc finger protein 82 homolog; Zfp-82; Zinc finger protein 545
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MGPVRLGILLFLFLAVHEAWAGMLKEEDDDTERLPSKCEVCKLLSTELQAELSRTGRSRE
VLELGQVLDTGKRKRHVPYSVSETRLEEALENLCERILDYSVHAERKGSLRYAKGQSQTM
ATLKGLVQKGVKVDLGIPLELWDEPSVEVTYLKKQCETMLEEFEDIVGDWYFHHQEQPLQ
NFLCEGHVLPAAETACLQETWTGKEITDGEEKTEGEEEQEEEEEEEEEEGGDKMTKTGSH
PKLDREDL
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
Q8N141
Ensemble ID
ENST00000392161.4
HGNC ID
HGNC:28682

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C321(13.30)  LDD0209  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0246  AC128 PaTu 8988t C321(1.15)  LDD1125  [2]
 LDCM0247  AC129 PaTu 8988t C321(1.22)  LDD1126  [2]
 LDCM0249  AC130 PaTu 8988t C321(1.03)  LDD1128  [2]
 LDCM0250  AC131 PaTu 8988t C321(0.95)  LDD1129  [2]
 LDCM0251  AC132 PaTu 8988t C321(1.17)  LDD1130  [2]
 LDCM0252  AC133 PaTu 8988t C321(1.54)  LDD1131  [2]
 LDCM0253  AC134 PaTu 8988t C321(1.32)  LDD1132  [2]
 LDCM0254  AC135 PaTu 8988t C321(1.36)  LDD1133  [2]
 LDCM0255  AC136 PaTu 8988t C321(1.30)  LDD1134  [2]
 LDCM0256  AC137 PaTu 8988t C321(1.42)  LDD1135  [2]
 LDCM0257  AC138 PaTu 8988t C321(1.01)  LDD1136  [2]
 LDCM0258  AC139 PaTu 8988t C321(1.19)  LDD1137  [2]
 LDCM0260  AC140 PaTu 8988t C321(1.12)  LDD1139  [2]
 LDCM0261  AC141 PaTu 8988t C321(0.98)  LDD1140  [2]
 LDCM0262  AC142 PaTu 8988t C321(1.07)  LDD1141  [2]
 LDCM0276  AC17 PaTu 8988t C321(0.90)  LDD1155  [2]
 LDCM0277  AC18 PaTu 8988t C321(1.02)  LDD1156  [2]
 LDCM0278  AC19 PaTu 8988t C321(0.86)  LDD1157  [2]
 LDCM0280  AC20 PaTu 8988t C321(1.02)  LDD1159  [2]
 LDCM0281  AC21 PaTu 8988t C321(0.94)  LDD1160  [2]
 LDCM0282  AC22 PaTu 8988t C321(1.03)  LDD1161  [2]
 LDCM0283  AC23 PaTu 8988t C321(1.28)  LDD1162  [2]
 LDCM0284  AC24 PaTu 8988t C321(1.26)  LDD1163  [2]
 LDCM0332  AC68 PaTu 8988t C321(0.90)  LDD1211  [2]
 LDCM0333  AC69 PaTu 8988t C321(1.04)  LDD1212  [2]
 LDCM0335  AC70 PaTu 8988t C321(1.29)  LDD1214  [2]
 LDCM0336  AC71 PaTu 8988t C321(0.83)  LDD1215  [2]
 LDCM0337  AC72 PaTu 8988t C321(0.78)  LDD1216  [2]
 LDCM0338  AC73 PaTu 8988t C321(1.10)  LDD1217  [2]
 LDCM0339  AC74 PaTu 8988t C321(0.61)  LDD1218  [2]
 LDCM0340  AC75 PaTu 8988t C321(0.94)  LDD1219  [2]
 LDCM0341  AC76 PaTu 8988t C321(1.11)  LDD1220  [2]
 LDCM0342  AC77 PaTu 8988t C321(0.89)  LDD1221  [2]
 LDCM0343  AC78 PaTu 8988t C321(0.82)  LDD1222  [2]
 LDCM0344  AC79 PaTu 8988t C321(0.82)  LDD1223  [2]
 LDCM0346  AC80 PaTu 8988t C321(0.97)  LDD1225  [2]
 LDCM0347  AC81 PaTu 8988t C321(1.19)  LDD1226  [2]
 LDCM0348  AC82 PaTu 8988t C321(0.93)  LDD1227  [2]
 LDCM0367  CL1 PaTu 8988t C321(1.08)  LDD1246  [2]
 LDCM0368  CL10 PaTu 8988t C321(1.32)  LDD1247  [2]
 LDCM0374  CL105 PaTu 8988t C321(1.00)  LDD1253  [2]
 LDCM0375  CL106 PaTu 8988t C321(0.92)  LDD1254  [2]
 LDCM0376  CL107 PaTu 8988t C321(1.02)  LDD1255  [2]
 LDCM0377  CL108 PaTu 8988t C321(1.01)  LDD1256  [2]
 LDCM0378  CL109 PaTu 8988t C321(1.17)  LDD1257  [2]
 LDCM0379  CL11 PaTu 8988t C321(1.12)  LDD1258  [2]
 LDCM0380  CL110 PaTu 8988t C321(1.11)  LDD1259  [2]
 LDCM0381  CL111 PaTu 8988t C321(1.33)  LDD1260  [2]
 LDCM0390  CL12 PaTu 8988t C321(1.23)  LDD1269  [2]
 LDCM0400  CL13 PaTu 8988t C321(1.57)  LDD1279  [2]
 LDCM0401  CL14 PaTu 8988t C321(1.41)  LDD1280  [2]
 LDCM0402  CL15 PaTu 8988t C321(1.22)  LDD1281  [2]
 LDCM0403  CL16 PaTu 8988t C321(1.04)  LDD1282  [2]
 LDCM0404  CL17 PaTu 8988t C321(1.19)  LDD1283  [2]
 LDCM0405  CL18 PaTu 8988t C321(1.07)  LDD1284  [2]
 LDCM0406  CL19 PaTu 8988t C321(1.08)  LDD1285  [2]
 LDCM0407  CL2 PaTu 8988t C321(1.34)  LDD1286  [2]
 LDCM0408  CL20 PaTu 8988t C321(1.07)  LDD1287  [2]
 LDCM0409  CL21 PaTu 8988t C321(1.30)  LDD1288  [2]
 LDCM0410  CL22 PaTu 8988t C321(1.19)  LDD1289  [2]
 LDCM0411  CL23 PaTu 8988t C321(1.23)  LDD1290  [2]
 LDCM0412  CL24 PaTu 8988t C321(1.16)  LDD1291  [2]
 LDCM0413  CL25 PaTu 8988t C321(1.10)  LDD1292  [2]
 LDCM0414  CL26 PaTu 8988t C321(1.22)  LDD1293  [2]
 LDCM0415  CL27 PaTu 8988t C321(1.27)  LDD1294  [2]
 LDCM0416  CL28 PaTu 8988t C321(1.18)  LDD1295  [2]
 LDCM0417  CL29 PaTu 8988t C321(1.18)  LDD1296  [2]
 LDCM0418  CL3 PaTu 8988t C321(1.23)  LDD1297  [2]
 LDCM0419  CL30 PaTu 8988t C321(1.20)  LDD1298  [2]
 LDCM0429  CL4 PaTu 8988t C321(1.25)  LDD1308  [2]
 LDCM0436  CL46 PaTu 8988t C321(1.10)  LDD1315  [2]
 LDCM0437  CL47 PaTu 8988t C321(1.34)  LDD1316  [2]
 LDCM0438  CL48 PaTu 8988t C321(1.23)  LDD1317  [2]
 LDCM0439  CL49 PaTu 8988t C321(1.17)  LDD1318  [2]
 LDCM0440  CL5 PaTu 8988t C321(1.41)  LDD1319  [2]
 LDCM0441  CL50 PaTu 8988t C321(1.32)  LDD1320  [2]
 LDCM0442  CL51 PaTu 8988t C321(1.16)  LDD1321  [2]
 LDCM0443  CL52 PaTu 8988t C321(1.25)  LDD1322  [2]
 LDCM0444  CL53 PaTu 8988t C321(1.46)  LDD1323  [2]
 LDCM0445  CL54 PaTu 8988t C321(1.28)  LDD1324  [2]
 LDCM0446  CL55 PaTu 8988t C321(1.26)  LDD1325  [2]
 LDCM0447  CL56 PaTu 8988t C321(0.53)  LDD1326  [2]
 LDCM0448  CL57 PaTu 8988t C321(2.20)  LDD1327  [2]
 LDCM0449  CL58 PaTu 8988t C321(1.38)  LDD1328  [2]
 LDCM0450  CL59 PaTu 8988t C321(2.04)  LDD1329  [2]
 LDCM0451  CL6 PaTu 8988t C321(1.28)  LDD1330  [2]
 LDCM0452  CL60 PaTu 8988t C321(1.82)  LDD1331  [2]
 LDCM0462  CL7 PaTu 8988t C321(1.45)  LDD1341  [2]
 LDCM0473  CL8 PaTu 8988t C321(1.58)  LDD1352  [2]
 LDCM0484  CL9 PaTu 8988t C321(1.32)  LDD1363  [2]
 LDCM0022  KB02 22RV1 C321(1.99)  LDD2243  [3]
 LDCM0023  KB03 Jurkat C321(13.30)  LDD0209  [1]
 LDCM0024  KB05 IGR37 C321(1.60)  LDD3314  [3]

References

1 Covalent Inhibition by a Natural Product-Inspired Latent Electrophile. J Am Chem Soc. 2023 May 24;145(20):11097-11109. doi: 10.1021/jacs.3c00598. Epub 2023 May 15.
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840