Details of the Target

General Information of Target

Target ID LDTP03796
Target Name Vascular endothelial growth factor receptor 2 (KDR)
Gene Name KDR
Gene ID 3791
Synonyms
FLK1; VEGFR2; Vascular endothelial growth factor receptor 2; VEGFR-2; EC 2.7.10.1; Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; KDR; Protein-tyrosine kinase receptor flk-1; CD antigen CD309
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MQSKVLLAVALWLCVETRAASVGLPSVSLDLPRLSIQKDILTIKANTTLQITCRGQRDLD
WLWPNNQSGSEQRVEVTECSDGLFCKTLTIPKVIGNDTGAYKCFYRETDLASVIYVYVQD
YRSPFIASVSDQHGVVYITENKNKTVVIPCLGSISNLNVSLCARYPEKRFVPDGNRISWD
SKKGFTIPSYMISYAGMVFCEAKINDESYQSIMYIVVVVGYRIYDVVLSPSHGIELSVGE
KLVLNCTARTELNVGIDFNWEYPSSKHQHKKLVNRDLKTQSGSEMKKFLSTLTIDGVTRS
DQGLYTCAASSGLMTKKNSTFVRVHEKPFVAFGSGMESLVEATVGERVRIPAKYLGYPPP
EIKWYKNGIPLESNHTIKAGHVLTIMEVSERDTGNYTVILTNPISKEKQSHVVSLVVYVP
PQIGEKSLISPVDSYQYGTTQTLTCTVYAIPPPHHIHWYWQLEEECANEPSQAVSVTNPY
PCEEWRSVEDFQGGNKIEVNKNQFALIEGKNKTVSTLVIQAANVSALYKCEAVNKVGRGE
RVISFHVTRGPEITLQPDMQPTEQESVSLWCTADRSTFENLTWYKLGPQPLPIHVGELPT
PVCKNLDTLWKLNATMFSNSTNDILIMELKNASLQDQGDYVCLAQDRKTKKRHCVVRQLT
VLERVAPTITGNLENQTTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIVLKDGNR
NLTIRRVRKEDEGLYTCQACSVLGCAKVEAFFIIEGAQEKTNLEIIILVGTAVIAMFFWL
LLVIILRTVKRANGGELKTGYLSIVMDPDELPLDEHCERLPYDASKWEFPRDRLKLGKPL
GRGAFGQVIEADAFGIDKTATCRTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVN
LLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPYKTKGARFRQGKDYVGAIPVDLK
RRLDSITSSQSSASSGFVEEKSLSDVEEEEAPEDLYKDFLTLEHLICYSFQVAKGMEFLA
SRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDR
VYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTML
DCWHGEPSQRPTFSELVEHLGNLLQANAQQDGKDYIVLPISETLSMEEDSGLSLPTSPVS
CMEEEEVCDPKFHYDNTAGISQYLQNSKRKSRPVSVKTFEDIPLEEPEVKVIPDDNQTDS
GMVLASEELKTLEDRTKLSPSFGGMVPSKSRESVASEGSNQTSGYQSGYHSDDTDTTVYS
SEEAELLKLIEIGVQTGSTAQILQPDSGTTLSSPPV
Target Type
Successful
Target Bioclass
Enzyme
Family
Protein kinase superfamily, Tyr protein kinase family, CSF-1/PDGF receptor subfamily
Subcellular location
Secreted; Cell membrane; Cell junction
Function
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain, such as isoform 2 and isoform 3, may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. Isoform 2 plays an important role as negative regulator of VEGFA- and VEGFC-mediated lymphangiogenesis by limiting the amount of free VEGFA and/or VEGFC and preventing their binding to FLT4. Modulates FLT1 and FLT4 signaling by forming heterodimers. Binding of vascular growth factors to isoform 1 leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate and the activation of protein kinase C. Mediates activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Mediates phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, reorganization of the actin cytoskeleton and activation of PTK2/FAK1. Required for VEGFA-mediated induction of NOS2 and NOS3, leading to the production of the signaling molecule nitric oxide (NO) by endothelial cells. Phosphorylates PLCG1. Promotes phosphorylation of FYN, NCK1, NOS3, PIK3R1, PTK2/FAK1 and SRC.
TTD ID
T80975
Uniprot ID
P35968
DrugMap ID
TTPFN62
Ensemble ID
ENST00000263923.5
HGNC ID
HGNC:6307
ChEMBL ID
CHEMBL279

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
COLO792 SNV: p.S1037L .
DEL SNV: p.G255R .
DU145 SNV: p.C466F .
FTC133 SNV: p.P230L .
HCT15 SNV: p.S925F .
HEPG2 SNV: p.Y357N .
HS936T Deletion: p.K287del .
HT115 SNV: p.S1290N; p.D1312N .
KMRC1 SNV: p.S1037L .
LNCaP clone FGC SNV: p.A1065T .
LS180 SNV: p.A10T .
MCC13 SNV: p.G255E; p.G638E .
MDST8 SNV: p.R1032Q .
MEWO SNV: p.S1281F .
MFE319 SNV: p.A750T .
NOMO1 SNV: p.F1212C .
RL952 SNV: p.D710A .
SKMEL5 SNV: p.S633F .
SW756 SNV: p.G220V .
TCCSUP SNV: p.G1261D .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info  		K1120(4.76)  LDD0277  [1]
AHL-Pu-1
 Probe Info  		C103(2.15)  LDD0169  [2]
DBIA
 Probe Info  		C53(1.00)  LDD1514  [3]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0026  4SU-RNA+native RNA HEK-293T C103(2.15)  LDD0169  [2]
 LDCM0284  AC24 HEK-293T C53(0.98)  LDD1523  [3]
 LDCM0293  AC32 HEK-293T C53(1.00)  LDD1532  [3]
 LDCM0302  AC40 HEK-293T C53(1.17)  LDD1541  [3]
 LDCM0310  AC48 HEK-293T C53(1.08)  LDD1549  [3]
 LDCM0319  AC56 HEK-293T C53(1.02)  LDD1558  [3]
 LDCM0328  AC64 HEK-293T C53(1.07)  LDD1567  [3]
 LDCM0345  AC8 HEK-293T C53(1.03)  LDD1569  [3]
 LDCM0275  AKOS034007705 HEK-293T C53(1.00)  LDD1514  [3]
 LDCM0372  CL103 HEK-293T C53(1.13)  LDD1576  [3]
 LDCM0376  CL107 HEK-293T C53(1.10)  LDD1580  [3]
 LDCM0381  CL111 HEK-293T C53(1.11)  LDD1585  [3]
 LDCM0385  CL115 HEK-293T C53(1.17)  LDD1589  [3]
 LDCM0389  CL119 HEK-293T C53(1.19)  LDD1593  [3]
 LDCM0390  CL12 HEK-293T C53(1.08)  LDD1594  [3]
 LDCM0394  CL123 HEK-293T C53(0.90)  LDD1598  [3]
 LDCM0398  CL127 HEK-293T C53(1.08)  LDD1602  [3]
 LDCM0402  CL15 HEK-293T C53(1.13)  LDD1606  [3]
 LDCM0412  CL24 HEK-293T C53(1.17)  LDD1616  [3]
 LDCM0415  CL27 HEK-293T C53(1.07)  LDD1619  [3]
 LDCM0418  CL3 HEK-293T C53(1.10)  LDD1622  [3]
 LDCM0425  CL36 HEK-293T C53(1.00)  LDD1629  [3]
 LDCM0428  CL39 HEK-293T C53(1.06)  LDD1632  [3]
 LDCM0438  CL48 HEK-293T C53(0.99)  LDD1642  [3]
 LDCM0452  CL60 HEK-293T C53(1.14)  LDD1655  [3]
 LDCM0455  CL63 HEK-293T C53(1.17)  LDD1658  [3]
 LDCM0465  CL72 HEK-293T C53(1.13)  LDD1668  [3]
 LDCM0478  CL84 HEK-293T C53(1.07)  LDD1681  [3]
 LDCM0481  CL87 HEK-293T C53(1.04)  LDD1684  [3]
 LDCM0491  CL96 HEK-293T C53(1.09)  LDD1694  [3]
 LDCM0494  CL99 HEK-293T C53(1.14)  LDD1697  [3]
 LDCM0495  E2913 HEK-293T C53(1.12)  LDD1698  [3]
 LDCM0468  Fragment33 HEK-293T C53(1.05)  LDD1671  [3]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 7 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Hepatocyte growth factor receptor (MET) Tyr protein kinase family P08581
Platelet-derived growth factor receptor beta (PDGFRB) Tyr protein kinase family P09619
Vascular endothelial growth factor receptor 2 (KDR) Tyr protein kinase family P35968
Vascular endothelial growth factor receptor 3 (FLT4) Tyr protein kinase family P35916
Proto-oncogene tyrosine-protein kinase Src (SRC) Tyr protein kinase family P12931
Tyrosine-protein phosphatase non-receptor type 6 (PTPN6) Protein-tyrosine phosphatase family P29350
Receptor-type tyrosine-protein phosphatase eta (PTPRJ) Protein-tyrosine phosphatase family Q12913
Transporter and channel
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Importin subunit alpha-3 (KPNA4) Importin alpha family O00629
Neuropilin-1 (NRP1) Neuropilin family O14786
Vascular endothelial growth factor C (VEGFC) PDGF/VEGF growth factor family P49767
Programmed cell death protein 6 (PDCD6) . O75340
Immunoglobulin
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG2) . P98160
Other
Click To Hide/Show 5 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Gremlin-1 (GREM1) DAN family O60565
Integrin alpha-2 (ITGA2) Integrin alpha chain family P17301
Vascular endothelial growth factor A, long form (VEGFA) PDGF/VEGF growth factor family P15692
Galectin-1 (LGALS1) . P09382
SH2/SH3 adapter protein NCK1 (NCK1) . P16333

The Drug(s) Related To This Target

Approved
Click To Hide/Show 20 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Ramucirumab Monoclonal antibody D09HVD
Axitinib Small molecular drug D01ZRI
Cabozantinib Small molecular drug D0IQ6P
Fostamatinib Small molecular drug DB12010
Lenvatinib Small molecular drug D0R0FO
Midostaurin Small molecular drug DB06595
Nintedanib Small molecular drug DB09079
Pazopanib Small molecular drug DB06589
Pazopanib Hcl Small molecular drug D0F0ZY
Ponatinib Small molecular drug DB08901
Regorafenib Small molecular drug D09GDD
Romiplostim Small molecular drug D01PZD
Sorafenib Small molecular drug D0W5HK
Sunitinib Small molecular drug D0R0MW
Tivozanib Small molecular drug D0W7JZ
Vandetanib Small molecular drug D0G6QF
Yn-968d1 Small molecular drug D0SZ6E
Erdafitinib . DB12147
Pralsetinib . DB15822
Ripretinib . DB14840
Phase 3
Click To Hide/Show 9 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Rosiglitazone + Metformin Combination drug (small molecular drug) D0A1AQ
Brivanib Small molecular drug D0HS5V
Cediranib Small molecular drug D09VMI
E-3810 Small molecular drug D02WVT
Hki-272 Small molecular drug D0Q9CY
Rivoceranib Small molecular drug D0D7BX
Fruquintinib . D03JTG
Mgcd516 . D05BLN
Sulfatinib . D05PWX
Phase 2
Click To Hide/Show 15 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Alacizumab Pegol Antibody D0HN7I
Ttac-0001 Antibody D09LOZ
Bay-57-9352 Small molecular drug D07NOI
Bms-690514 Small molecular drug D0R6UV
Cp-547632 Small molecular drug D00YPR
Delphinidin Small molecular drug D0ZN1R
Famitinib Small molecular drug D0Z6MT
Mk-2461 Small molecular drug D00DRL
Raf265 Small molecular drug D03AND
Vatalanib Small molecular drug D0P6DJ
Xl880 Small molecular drug D0D1GF
Elpamotide Vaccine D0Q0HZ
Otsgc-a24 Vaccine D04NOE
Anti-vegfr2 Cd8 Cell Therapy . D0U6BQ
L-dos47 . DN3Z5D
Phase 1
Click To Hide/Show 11 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Cep-11981 Small molecular drug D0FD6D
Cyc116 Small molecular drug D0CY1B
E-7050 Small molecular drug D09ETH
Krn633 Small molecular drug D07HRU
Osi-930 Small molecular drug D0N8RV
Pf-00337210 Small molecular drug D0ZI5A
Plx-4720 Small molecular drug D0F5JZ
Tak-593 Small molecular drug D0T2ER
Altiratinib . D0FA6S
Pegdinetanib . D0GM6E
Xl999 . D07PNT
Investigative
Click To Hide/Show 91 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
R-84 Antibody D07OIZ
(2-methoxy-phenyl)-(5-phenyl-oxazol-2-yl)-amine Small molecular drug D06GJO
(3-phenoxy-phenyl)-(5-phenyl-oxazol-2-yl)-amine Small molecular drug D0A9ZQ
(4-phenoxy-phenyl)-quinazolin-4-yl-amine Small molecular drug D07AIB
(5-phenyl-oxazol-2-yl)-m-tolyl-amine Small molecular drug D0D3YL
2-(1h-indazol-3-yl)-1h-benzo[D]Imidazole Small molecular drug D0XC6G
2-(5-phenyl-oxazol-2-ylamino)-benzonitrile Small molecular drug D03HQK
2-(P-toluidino)-4-phenylpyrimidine-5-carbonitrile Small molecular drug D0E9DI
2-(Pyrimidin-4-ylamino)Thiazole-5-carbonitrile Small molecular drug D0J3OZ
3,4-di-(4-methoxyphenyl)-1h-pyrrole-2,5-dione Small molecular drug D00NYT
3,4-diphenyl-1h-pyrrole-2,5-dione Small molecular drug D0C3WY
3,6-di-pyridin-4-yl-pyrazolo[1,5-a]Pyrimidine Small molecular drug D0YN1E
3-((3-bromothiophen-2-yl)Methylene)Indolin-2-one Small molecular drug D01LEV
3-(1h-indol-2-yl)-1h-quinolin-2-one Small molecular drug D0M9OF
3-(4-aminophenyl)Thieno[3,2-c]Pyridin-4-amine Small molecular drug D00YWZ
3-(4-methoxyphenyl)-4-phenyl-1h-pyrrole-2,5-dione Small molecular drug D0EK0G
3-(5-phenyl-oxazol-2-ylamino)-benzonitrile Small molecular drug D0J2XD
3-(5-thiophen-3-yl-pyridin-3-yl)-1h-indole Small molecular drug D0UX3T
3-benzimidazol-2-ylhydroquinolin-2-one Small molecular drug D07QMC
3-methyl-1h-thieno[2,3-c]Pyrazole-5-carboxamide Small molecular drug D0F0AU
3-phenyl-1,4-dihydroindeno[1,2-c]Pyrazole Small molecular drug D09TQP
4-(4-aminophenyl)-1h-indazol-3yl-amine Small molecular drug D0Y9GK
4-(4-m-tolylamino-phthalazin-1-yl)-benzamide Small molecular drug D09AKX
4-(4-p-tolylamino-phthalazin-1-yl)-benzamide Small molecular drug D08JSJ
4-(5-phenyl-oxazol-2-ylamino)-benzenesulfonamide Small molecular drug D09LEK
4-(Isoquinolin-5-yl)-n-m-tolylphthalazin-1-amine Small molecular drug D0D3QA
4-(Isoquinolin-5-yl)-n-o-tolylphthalazin-1-amine Small molecular drug D03HTT
4-chloro-n-(2-chloro-benzoyl)-benzenesulfonamide Small molecular drug D0UZ5W
4-chloro-n-(2-methyl-benzoyl)-benzenesulfonamide Small molecular drug D0V4BR
4-chloro-n-(3-chloro-benzoyl)-benzenesulfonamide Small molecular drug D05THI
4-chloro-n-(4-chloro-benzoyl)-benzenesulfonamide Small molecular drug D09MSA
4-chloro-n-(4-nitro-benzoyl)-benzenesulfonamide Small molecular drug D0C6OD
4-phenyl-2-(Phenylamino)Pyrimidine-5-carbonitrile Small molecular drug D06BVH
4-[3-hydroxyanilino]-6,7-dimethoxyquinazoline Small molecular drug D0KH5T
5-(4-methoxy-phenyl)-1-phenyl-1h-benzoimidazole Small molecular drug D0U3ZP
6-(1h-benzoimidazol-2-yl)-benzocyclohepten-7-one Small molecular drug D00MCJ
6-o-tolylquinazolin-2-amine Small molecular drug D09HXU
8-methyl-4h,7h-indolo[6,5,4-cd]Indol-5-one Small molecular drug D04RQU
Aal-993 Small molecular drug D0EE6A
Ag-e-85378 Small molecular drug D07SRX
Ast-487 Small molecular drug D0N7AJ
Bibf-1202 Small molecular drug D05GMB
Bms-536924 Small molecular drug D0M4SY
Bms-645737 Small molecular drug D0Z7TM
Bx-795 Small molecular drug D0RG0Z
Bx-912 Small molecular drug D0IX7Y
Cb-676475 Small molecular drug D0C6KI
Cep-5104 Small molecular drug D09QBA
Foretinib Small molecular drug DB12307
Im-023911 Small molecular drug D0ST4P
Im-094261 Small molecular drug D0Z8TR
Im-094882 Small molecular drug D0A9ZP
Indolin-2-one Deriv. 4b Small molecular drug D00GVV
Isoindolinone Urea Derivative Small molecular drug D02AOT
Jnj-38158471 Small molecular drug D0Q4EQ
K-252a Analogue Small molecular drug D02RWK
Ki-20227 Small molecular drug D08BJR
L000021649 Small molecular drug D0E3HC
N-(2,4-dichloro-benzoyl)-benzenesulfonamide Small molecular drug D07XBW
N-(3-bromo-benzoyl)-4-chloro-benzenesulfonamide Small molecular drug D0M2QA
Phenyl-(5-phenyl-oxazol-2-yl)-amine Small molecular drug D0BM4F
Pmid22765894c8h Small molecular drug D0C2GE
Pmid23639540c13a Small molecular drug D0PP6Y
Pp121 Small molecular drug D03EHM
Pyrazolo[1,5-a]Pyrimidine 3g Small molecular drug D09LKM
Ro-4396686 Small molecular drug D09XIL
Su-11652 Small molecular drug D09LPL
Tg-100435 Small molecular drug D0H1OK
Tg-100801 Small molecular drug DB05075
Vatalanib Small molecular drug DB04879
Vegf Receptor 2 Kinase Inhibitor I Small molecular drug D07OSK
[3-(5-phenyl-oxazol-2-ylamino)-phenyl]-methanol Small molecular drug D0V9DQ
1-{4-[4-amino-6-(4-methoxyphenyl)Furo[23-d]Pyrimidin-5-yl]Phenyl}-3-[2-fluoro-5-(Trifluoromethyl)Phenyl]Urea . DB04727
3-(2-aminoquinazolin-6-yl)-1-(33-dimethylindolin-6-yl)-4-methylpyridin-2(1h)-one . DB07514
3-(2-aminoquinazolin-6-yl)-4-methyl-1-[3-(Trifluoromethyl)Phenyl]Pyridin-2(1h)-one . DB07528
4-[[2-[[4-chloro-3-(Trifluoromethyl)Phenyl]Amino]-3h-benzimidazol-5-yl]Oxy]-n-methyl-pyridine-2-carboxamide . DB06938
6-chloro-n-pyrimidin-5-yl-3-{[3-(Trifluoromethyl)Phenyl]Amino}-12-benzisoxazole-7-carboxamide . DB07326
Amg-429 . D0AK4H
Epi-0030 . D0R3IK
Linifanib . DB06080
N'-(6-aminopyridin-3-yl)-n-(2-cyclopentylethyl)-4-methyl-benzene-13-dicarboxamide . DB07537
N-(4-phenoxyphenyl)-2-[(Pyridin-4-ylmethyl)Amino]Nicotinamide . DB07183
N-(Cyclopropylmethyl)-4-(Methyloxy)-3-({5-[3-(3-pyridinyl)Phenyl]-13-oxazol-2-yl}Amino)Benzenesulfonamide . DB07333
N-cyclopropyl-6-[(67-dimethoxyquinolin-4-yl)Oxy]Naphthalene-1-carboxamide . DB07274
N-[5-(Ethylsulfonyl)-2-methoxyphenyl]-5-[3-(2-pyridinyl)Phenyl]-13-oxazol-2-amine . DB07334
N~4~-(3-methyl-1h-indazol-6-yl)-n~2~-(345-trimethoxyphenyl)Pyrimidine-24-diamine . DB08519
N~4~-methyl-n~4~-(3-methyl-1h-indazol-6-yl)-n~2~-(345-trimethoxyphenyl)Pyrimidine-24-diamine . DB08042
Olinvacimab . DB16265
Raf-265 . DB05984
Semaxanib . DB06436
Xl820 . DB05146
Patented
Click To Hide/Show 10 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Antibodie Derivative 10 Antibody D01AXK
Antibodie Derivative 6 Antibody D08XAY
Pyridine Derivative 18 Small molecular drug D0AK1F
Pyrimidine Derivative 12 Small molecular drug D0JU8E
Pyrimidine Derivative 13 Small molecular drug D0G1YI
Pyrimidine Derivative 14 Small molecular drug D06BTN
Pyrimidine Derivative 4 Small molecular drug D06HEO
Quinazoline Derivative 15 Small molecular drug D05PRG
Quinazoline Derivative 16 Small molecular drug D0DV4X
Quinoline And Quinazoline Derivative 1 Small molecular drug D08OXH
Discontinued
Click To Hide/Show 5 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Imc-1c11 Antibody D0E8VF
Ag1295 Small molecular drug D06GBK
Cep-5214 Small molecular drug D0H4GI
Motesanib Small molecular drug D00DQX
Su-14813 Small molecular drug D09DJU

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
2 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
3 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402