Details of the Target

General Information of Target

Target ID LDTP02607
Target Name Collagen alpha-3(VI) chain (COL6A3)
Gene Name COL6A3
Gene ID 1293
Synonyms
Collagen alpha-3(VI) chain
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MRKHRHLPLVAVFCLFLSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVRE
FLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTNQTGK
GLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDA
DEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDS
ADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYS
TKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSD
EIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIV
GVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQD
LIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSS
AGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSS
LVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRD
FVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTG
SALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQ
ANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILF
LFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEIL
NLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPA
SNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGA
PAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEF
YLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLT
ADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQV
ISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVD
YLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVS
RNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIARNADQEELVK
ISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFL
IDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVL
DAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFA
QVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATP
APPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGL
VQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLD
QRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVG
NVQELSELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGSRDQNVFVAQKGFES
KVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQ
HPYVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILV
GLERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQR
GDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFP
GEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNP
GQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGF
EGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPGP
KGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIR
GRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGDSIDQCALIQSIKDKCPCCYGPLECPVFP
TELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYNNEVTTEIRF
ADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPT
RASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLEN
VLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKK
YIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVD
FLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVIL
QAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKLVDKSTELNEEPLMRFGRLLPSFV
SSENAFYLSPDIRKQCDWFQGDQPTKNLVKFGHKQVNVPNNVTSSPTSNPVTTTKPVTTT
KPVTTTTKPVTTTTKPVTIINQPSVKPAAAKPAPAKPVAAKPVATKMATVRPPVAVKPAT
AAKPVAAKPAAVRPPAAAAAKPVATKPEVPRPQAAKPAATKPATTKPMVKMSREVQVFEI
TENSAKLHWERAEPPGPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGLLAGQTYHVAVVC
YLRSQVRATYHGSFSTKKSQPPPPQPARSASSSTINLMVSTEPLALTETDICKLPKDEGT
CRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAKPGVISVMGT
Target Type
Literature-reported
Target Bioclass
Other
Family
Type VI collagen family
Subcellular location
Secreted, extracellular space, extracellular matrix
Function Collagen VI acts as a cell-binding protein.
TTD ID
T83450
Uniprot ID
P12111
DrugMap ID
TT5WCAH
Ensemble ID
ENST00000295550.9
HGNC ID
HGNC:2213
ChEMBL ID
CHEMBL2364188

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
8505C Deletion: p.T2520KfsTer105 .
A2780 SNV: p.D979E .
AN3CA SNV: p.L1285P .
CCK81 SNV: p.P1630H; p.D2112G; p.C3137Y; p.C3158R .
DU145 SNV: p.P2682H .
EFO27 SNV: p.G1857D .
FUOV1 SNV: p.N1150S .
HCC44 SNV: p.N1684I .
HCT116 SNV: p.A2959V .
HCT15 SNV: p.V2963M .
HEC1 SNV: p.N84D; p.R2306H DBIA    Probe Info 
HEC1B SNV: p.N84D; p.R2306H .
HSC3 SNV: p.V1932A .
HT115 SNV: p.K120T .
IGROV1 Deletion: p.G339AfsTer15 .
IPC298 SNV: p.E1377Q .
K562 SNV: p.Q1811K .
KARPAS422 SNV: p.L2330I .
KYM1 SNV: p.P1366L .
LS513 SNV: p.V2778M .
MCC13 SNV: p.G559D; p.M1086I; p.E1333K .
MCC26 SNV: p.Q589Ter .
MEWO SNV: p.G1306R;p.G2210S;p.P2859S
Substitution: p.F2315_P2316delinsLS		 .
MFE296 SNV: p.G323D; p.G2276R .
MOLT4 SNV: p.S1860T .
NCIH1155 SNV: p.G1827D .
NCIH146 SNV: p.P2178L .
NCIH1993 SNV: p.P1428T .
NCIH2286 SNV: p.A923P; p.L1378M .
NCIH2291 SNV: p.S454C .
NCIH446 SNV: p.E1690Ter .
NCIH716 SNV: p.A2920G .
NCIH82 Deletion: p.Y1923CfsTer30 .
NUGC3 SNV: p.L2176F .
OPM2 SNV: p.I482N; p.F1439L .
PF382 Insertion: p.T2401NfsTer11 .
RKO Insertion: p.D670Ter
SNV: p.S668N;p.A1735T		 .
SNU1 SNV: p.V1060M .
T24 SNV: p.G2344R .
TE4 SNV: p.G2056R .
TOV21G SNV: p.K1694N .
U937 SNV: p.D360E .
WM2664 Insertion: p.H54TfsTer11
SNV: p.K3077N		 .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C775(1.23)  LDD3376  [1]
YN-1
 Probe Info  		N.A.  LDD0447  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C3162(1.05)  LDD1507  [3]
 LDCM0215  AC10 HEK-293T C3162(1.08)  LDD1508  [3]
 LDCM0226  AC11 HEK-293T C3162(1.08)  LDD1509  [3]
 LDCM0259  AC14 HEK-293T C3162(1.07)  LDD1512  [3]
 LDCM0270  AC15 HEK-293T C3162(1.05)  LDD1513  [3]
 LDCM0276  AC17 HEK-293T C3162(1.03)  LDD1515  [3]
 LDCM0277  AC18 HEK-293T C3162(1.04)  LDD1516  [3]
 LDCM0278  AC19 HEK-293T C3162(1.11)  LDD1517  [3]
 LDCM0279  AC2 HEK-293T C3162(1.06)  LDD1518  [3]
 LDCM0282  AC22 HEK-293T C3162(1.04)  LDD1521  [3]
 LDCM0283  AC23 HEK-293T C3162(1.07)  LDD1522  [3]
 LDCM0285  AC25 HEK-293T C3162(0.97)  LDD1524  [3]
 LDCM0286  AC26 HEK-293T C3162(1.00)  LDD1525  [3]
 LDCM0287  AC27 HEK-293T C3162(1.03)  LDD1526  [3]
 LDCM0290  AC3 HEK-293T C3162(1.05)  LDD1529  [3]
 LDCM0291  AC30 HEK-293T C3162(1.04)  LDD1530  [3]
 LDCM0292  AC31 HEK-293T C3162(1.05)  LDD1531  [3]
 LDCM0294  AC33 HEK-293T C3162(0.99)  LDD1533  [3]
 LDCM0295  AC34 HEK-293T C3162(1.07)  LDD1534  [3]
 LDCM0296  AC35 HEK-293T C3162(1.07)  LDD1535  [3]
 LDCM0299  AC38 HEK-293T C3162(1.10)  LDD1538  [3]
 LDCM0300  AC39 HEK-293T C3162(1.10)  LDD1539  [3]
 LDCM0303  AC41 HEK-293T C3162(1.07)  LDD1542  [3]
 LDCM0304  AC42 HEK-293T C3162(1.03)  LDD1543  [3]
 LDCM0305  AC43 HEK-293T C3162(1.16)  LDD1544  [3]
 LDCM0308  AC46 HEK-293T C3162(1.08)  LDD1547  [3]
 LDCM0309  AC47 HEK-293T C3162(1.13)  LDD1548  [3]
 LDCM0311  AC49 HEK-293T C3162(1.08)  LDD1550  [3]
 LDCM0313  AC50 HEK-293T C3162(1.06)  LDD1552  [3]
 LDCM0314  AC51 HEK-293T C3162(1.06)  LDD1553  [3]
 LDCM0317  AC54 HEK-293T C3162(1.02)  LDD1556  [3]
 LDCM0318  AC55 HEK-293T C3162(1.17)  LDD1557  [3]
 LDCM0320  AC57 HEK-293T C3162(1.07)  LDD1559  [3]
 LDCM0321  AC58 HEK-293T C3162(1.07)  LDD1560  [3]
 LDCM0322  AC59 HEK-293T C3162(1.00)  LDD1561  [3]
 LDCM0323  AC6 HEK-293T C3162(1.01)  LDD1562  [3]
 LDCM0326  AC62 HEK-293T C3162(1.00)  LDD1565  [3]
 LDCM0327  AC63 HEK-293T C3162(1.02)  LDD1566  [3]
 LDCM0334  AC7 HEK-293T C3162(1.11)  LDD1568  [3]
 LDCM0356  AKOS034007680 HEK-293T C3162(1.09)  LDD1570  [3]
 LDCM0367  CL1 HEK-293T C3162(0.98)  LDD1571  [3]
 LDCM0368  CL10 HEK-293T C3162(1.21)  LDD1572  [3]
 LDCM0369  CL100 HEK-293T C3162(1.13)  LDD1573  [3]
 LDCM0370  CL101 HEK-293T C3162(1.01)  LDD1574  [3]
 LDCM0371  CL102 HEK-293T C3162(1.24)  LDD1575  [3]
 LDCM0372  CL103 HEK-293T C3162(1.06)  LDD1576  [3]
 LDCM0373  CL104 HEK-293T C3162(1.15)  LDD1577  [3]
 LDCM0374  CL105 HEK-293T C3162(0.99)  LDD1578  [3]
 LDCM0375  CL106 HEK-293T C3162(1.04)  LDD1579  [3]
 LDCM0376  CL107 HEK-293T C3162(1.03)  LDD1580  [3]
 LDCM0377  CL108 HEK-293T C3162(1.02)  LDD1581  [3]
 LDCM0378  CL109 HEK-293T C3162(1.03)  LDD1582  [3]
 LDCM0379  CL11 HEK-293T C3162(1.08)  LDD1583  [3]
 LDCM0380  CL110 HEK-293T C3162(1.09)  LDD1584  [3]
 LDCM0381  CL111 HEK-293T C3162(1.01)  LDD1585  [3]
 LDCM0382  CL112 HEK-293T C3162(0.93)  LDD1586  [3]
 LDCM0383  CL113 HEK-293T C3162(0.99)  LDD1587  [3]
 LDCM0384  CL114 HEK-293T C3162(1.08)  LDD1588  [3]
 LDCM0385  CL115 HEK-293T C3162(1.03)  LDD1589  [3]
 LDCM0386  CL116 HEK-293T C3162(1.06)  LDD1590  [3]
 LDCM0387  CL117 HEK-293T C3162(1.02)  LDD1591  [3]
 LDCM0388  CL118 HEK-293T C3162(1.13)  LDD1592  [3]
 LDCM0389  CL119 HEK-293T C3162(1.05)  LDD1593  [3]
 LDCM0391  CL120 HEK-293T C3162(1.04)  LDD1595  [3]
 LDCM0392  CL121 HEK-293T C3162(0.95)  LDD1596  [3]
 LDCM0393  CL122 HEK-293T C3162(1.13)  LDD1597  [3]
 LDCM0394  CL123 HEK-293T C3162(1.15)  LDD1598  [3]
 LDCM0395  CL124 HEK-293T C3162(1.16)  LDD1599  [3]
 LDCM0396  CL125 HEK-293T C3162(0.98)  LDD1600  [3]
 LDCM0397  CL126 HEK-293T C3162(1.10)  LDD1601  [3]
 LDCM0398  CL127 HEK-293T C3162(1.01)  LDD1602  [3]
 LDCM0399  CL128 HEK-293T C3162(1.08)  LDD1603  [3]
 LDCM0400  CL13 HEK-293T C3162(0.96)  LDD1604  [3]
 LDCM0401  CL14 HEK-293T C3162(1.06)  LDD1605  [3]
 LDCM0402  CL15 HEK-293T C3162(1.11)  LDD1606  [3]
 LDCM0403  CL16 HEK-293T C3162(1.22)  LDD1607  [3]
 LDCM0404  CL17 HEK-293T C3162(1.16)  LDD1608  [3]
 LDCM0405  CL18 HEK-293T C3162(1.01)  LDD1609  [3]
 LDCM0406  CL19 HEK-293T C3162(1.24)  LDD1610  [3]
 LDCM0407  CL2 HEK-293T C3162(1.08)  LDD1611  [3]
 LDCM0410  CL22 HEK-293T C3162(1.09)  LDD1614  [3]
 LDCM0411  CL23 HEK-293T C3162(1.11)  LDD1615  [3]
 LDCM0413  CL25 HEK-293T C3162(1.03)  LDD1617  [3]
 LDCM0414  CL26 HEK-293T C3162(1.16)  LDD1618  [3]
 LDCM0415  CL27 HEK-293T C3162(1.00)  LDD1619  [3]
 LDCM0416  CL28 HEK-293T C3162(1.05)  LDD1620  [3]
 LDCM0417  CL29 HEK-293T C3162(1.05)  LDD1621  [3]
 LDCM0418  CL3 HEK-293T C3162(1.04)  LDD1622  [3]
 LDCM0419  CL30 HEK-293T C3162(1.03)  LDD1623  [3]
 LDCM0420  CL31 HEK-293T C3162(1.09)  LDD1624  [3]
 LDCM0423  CL34 HEK-293T C3162(1.15)  LDD1627  [3]
 LDCM0424  CL35 HEK-293T C3162(1.12)  LDD1628  [3]
 LDCM0426  CL37 HEK-293T C3162(0.98)  LDD1630  [3]
 LDCM0428  CL39 HEK-293T C3162(1.00)  LDD1632  [3]
 LDCM0429  CL4 HEK-293T C3162(1.23)  LDD1633  [3]
 LDCM0430  CL40 HEK-293T C3162(1.04)  LDD1634  [3]
 LDCM0431  CL41 HEK-293T C3162(1.08)  LDD1635  [3]
 LDCM0432  CL42 HEK-293T C3162(0.97)  LDD1636  [3]
 LDCM0433  CL43 HEK-293T C3162(1.00)  LDD1637  [3]
 LDCM0436  CL46 HEK-293T C3162(1.08)  LDD1640  [3]
 LDCM0437  CL47 HEK-293T C3162(1.06)  LDD1641  [3]
 LDCM0439  CL49 HEK-293T C3162(1.01)  LDD1643  [3]
 LDCM0440  CL5 HEK-293T C3162(1.02)  LDD1644  [3]
 LDCM0441  CL50 HEK-293T C3162(1.22)  LDD1645  [3]
 LDCM0443  CL52 HEK-293T C3162(1.12)  LDD1646  [3]
 LDCM0444  CL53 HEK-293T C3162(1.15)  LDD1647  [3]
 LDCM0445  CL54 HEK-293T C3162(1.43)  LDD1648  [3]
 LDCM0446  CL55 HEK-293T C3162(1.09)  LDD1649  [3]
 LDCM0449  CL58 HEK-293T C3162(1.27)  LDD1652  [3]
 LDCM0450  CL59 HEK-293T C3162(1.19)  LDD1653  [3]
 LDCM0451  CL6 HEK-293T C3162(1.08)  LDD1654  [3]
 LDCM0453  CL61 HEK-293T C3162(0.96)  LDD1656  [3]
 LDCM0454  CL62 HEK-293T C3162(1.11)  LDD1657  [3]
 LDCM0455  CL63 HEK-293T C3162(1.07)  LDD1658  [3]
 LDCM0456  CL64 HEK-293T C3162(1.14)  LDD1659  [3]
 LDCM0457  CL65 HEK-293T C3162(1.07)  LDD1660  [3]
 LDCM0458  CL66 HEK-293T C3162(1.07)  LDD1661  [3]
 LDCM0459  CL67 HEK-293T C3162(1.11)  LDD1662  [3]
 LDCM0462  CL7 HEK-293T C3162(1.22)  LDD1665  [3]
 LDCM0463  CL70 HEK-293T C3162(1.16)  LDD1666  [3]
 LDCM0464  CL71 HEK-293T C3162(1.16)  LDD1667  [3]
 LDCM0466  CL73 HEK-293T C3162(0.99)  LDD1669  [3]
 LDCM0467  CL74 HEK-293T C3162(1.07)  LDD1670  [3]
 LDCM0469  CL76 HEK-293T C3162(1.14)  LDD1672  [3]
 LDCM0470  CL77 HEK-293T C3162(1.15)  LDD1673  [3]
 LDCM0471  CL78 HEK-293T C3162(1.05)  LDD1674  [3]
 LDCM0472  CL79 HEK-293T C3162(1.13)  LDD1675  [3]
 LDCM0476  CL82 HEK-293T C3162(1.12)  LDD1679  [3]
 LDCM0477  CL83 HEK-293T C3162(1.15)  LDD1680  [3]
 LDCM0479  CL85 HEK-293T C3162(0.98)  LDD1682  [3]
 LDCM0480  CL86 HEK-293T C3162(1.13)  LDD1683  [3]
 LDCM0481  CL87 HEK-293T C3162(1.12)  LDD1684  [3]
 LDCM0482  CL88 HEK-293T C3162(1.15)  LDD1685  [3]
 LDCM0483  CL89 HEK-293T C3162(1.14)  LDD1686  [3]
 LDCM0485  CL90 HEK-293T C3162(1.35)  LDD1688  [3]
 LDCM0486  CL91 HEK-293T C3162(1.13)  LDD1689  [3]
 LDCM0489  CL94 HEK-293T C3162(1.07)  LDD1692  [3]
 LDCM0490  CL95 HEK-293T C3162(1.40)  LDD1693  [3]
 LDCM0492  CL97 HEK-293T C3162(0.99)  LDD1695  [3]
 LDCM0493  CL98 HEK-293T C3162(1.06)  LDD1696  [3]
 LDCM0494  CL99 HEK-293T C3162(0.96)  LDD1697  [3]
 LDCM0495  E2913 HEK-293T C3162(0.99)  LDD1698  [3]
 LDCM0468  Fragment33 HEK-293T C3162(1.03)  LDD1671  [3]
 LDCM0427  Fragment51 HEK-293T C3162(1.08)  LDD1631  [3]
 LDCM0022  KB02 HEK-293T C3162(0.92)  LDD1492  [3]
 LDCM0023  KB03 HEK-293T C3162(0.95)  LDD1497  [3]
 LDCM0024  KB05 ONS-76 C775(1.23)  LDD3376  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
2 Ynamide Electrophile for the Profiling of Ligandable Carboxyl Residues in Live Cells and the Development of New Covalent Inhibitors. J Med Chem. 2022 Aug 11;65(15):10408-10418. doi: 10.1021/acs.jmedchem.2c00272. Epub 2022 Jul 26.
3 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402