General Information of Experiment

Probe Name C125  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 7 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP06375  Delta(24)-sterol reductase (DHCR24) 10.0
 LDTP01329  Lathosterol oxidase (SC5D) 8.5
 LDTP00428  Tripeptidyl-peptidase 1 (TPP1) 7.9
 LDTP02223  Cathepsin B (CTSB) 6.5
 LDTP13147  Cathepsin Z (CTSZ) 6.1
 LDTP10888  Legumain (LGMN) 5.0
 LDTP02141  Alpha-galactosidase A (GLA) 5.0
Cytokine and receptor
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP02775  Interferon gamma receptor 1 (IFNGR1) 7.3

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587