General Information of Experiment

Probe Name AR-1  Probe Info 
Probe concentration 100 nM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
SILAC
Competitor Name Arenobufagin  Competitor Info 
Competitor Concentration 1000 nM
In Vivo Experiment Model Model Type Living cell
Derived Tissue Liver
Disease Model Hepatoblastoma [ICD-11:DB91]
Model Name Human hepatoblastoma cells (Hep-G2)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP12538  Ras-related protein Rab-6B (RAB6B) 1.6
 LDTP02375  Poly [ADP-ribose] polymerase 1 (PARP1) 1.5
Other
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03554  Sorcin (SRI) 1.4

References

1 Affinity-Based Protein Profiling Reveals Cellular Targets of Photoreactive Anticancer Inhibitors. ACS Chem Biol. 2019 Dec 20;14(12):2546-2552. doi: 10.1021/acschembio.9b00784. Epub 2019 Nov 26.