Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name HM-2  Probe Info 
Probe concentration 5 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
SILAC
Competitor Name HM30181  Competitor Info 
Competitor Concentration 25 uM
In Vivo Experiment Model Model Type Living cell
Derived Tissue Liver
Disease Model Hepatoblastoma [ICD-11:DB91]
Model Name Human hepatoblastoma cells (Hep-G2)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP04084  Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase (NOP2) 3.4
 LDTP02254  ATP-dependent translocase ABCB1 (ABCB1) 2.2
 LDTP12469  Nucleolar RNA helicase 2 (DDX21) 1.8
Other
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10046  Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ERGIC1) 2.0

References

1 Affinity-Based Protein Profiling Reveals Cellular Targets of Photoreactive Anticancer Inhibitors. ACS Chem Biol. 2019 Dec 20;14(12):2546-2552. doi: 10.1021/acschembio.9b00784. Epub 2019 Nov 26.