General Information of Experiment

Probe Name IPM  Probe Info 
Probe concentration 100 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
LFQ
Competitor Name Abegg_cp(-)-10  Competitor Info 
Competitor Concentration 30 uM
In Vivo Experiment Model Model Type Cell lysate
Derived Tissue Cervix uteri
Disease Model Endocervical adenocarcinoma [ICD-11:2C77]
Model Name Human endocervical adenocarcinoma cell lysate (HeLa)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Sites Binding Ratio
 LDTP13904  Probable ATP-dependent RNA helicase DDX52 (DDX52) C536 2.3
 LDTP09819  Unconventional myosin-XVIIIa (MYO18A) C1699 2.1
 LDTP04251  Elongation factor Tu, mitochondrial (TUFM) C130 2.0
Transporter and channel
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Sites Binding Ratio
 LDTP00196  Unconventional myosin-Ic (MYO1C) C802 2.3
Transcription factor
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Sites Binding Ratio
 LDTP08216  Protein polybromo-1 (PBRM1) C1163 2.2
Other
Click to Show/Hide to Show 4 Protein Related to This Bioclass
Target ID Target Name Binding Sites Binding Ratio
 LDTP01252  Cold shock domain-containing protein E1 (CSDE1) C42 3.2
 LDTP02941  Integrin beta-5 (ITGB5) C211 2.1
 LDTP09969  Lipoma-preferred partner (LPP) C364 2.1
 LDTP16285  Transducin beta-like protein 2 (TBL2) C44 2.0

References

1 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255