General Information of Experiment

Probe Name 7-N3  Probe Info 
Probe concentration 10 uM
Criteria Quantification: Probe vs DMSO
Quantitative Method
LFQ
In Vivo Experiment Model Model Type Living cell
Derived Tissue Colon
Disease Model Cecum adenocarcinoma [ICD-11:2B90]
Model Name Human cecum adenocarcinoma cells (NCI-H716)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP04876  Actin, cytoplasmic 1 (ACTB) 1.2
 LDTP02159  Alpha-enolase (ENO1) 0.8
 LDTP02672  Elongation factor 2 (EEF2) 0.8
Other
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03792  Keratin, type II cytoskeletal 2 epidermal (KRT2) 1.6
 LDTP13746  Serine/arginine repetitive matrix protein 2 (SRRM2) 1.2
 LDTP07954  Arginine/serine-rich coiled-coil protein 2 (RSRC2) 0.8

References

1 A Gut-Restricted Lithocholic Acid Analog as an Inhibitor of Gut Bacterial Bile Salt Hydrolases. ACS Chem Biol. 2021 Aug 20;16(8):1401-1412. doi: 10.1021/acschembio.1c00192. Epub 2021 Jul 19.