Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name	IA-alkyne			Probe Info
Probe concentration	100 uM
Criteria	Quantification: Probe vs (Probe+Competitor)
Quantitative Method	LFQ
Competitor Name	EN4			Competitor Info
Competitor Concentration	50 uM
*In Vivo* Experiment Model**	Model Type		Living cell
	Derived Tissue		Breast
	Disease Model	Breast cancer [ICD-11:2C82]
	Model Name	Human breast cancer cells (231MFP)

Interaction Altas of This Experiment [1]

Transporter and channel

Click to Show/Hide to Show 2 Protein Related to This Bioclass

Target ID	Target Name				Binding Sites	Binding Ratio
LDTP12142	Exportin-5 (XPO5)				C941	6.9
LDTP03211	Integrin alpha-6 (ITGA6)				C175	3.9

Transcription factor

Click to Show/Hide to Show 1 Protein Related to This Bioclass

Target ID	Target Name				Binding Sites	Binding Ratio
LDTP02111	Transcription factor Jun (JUN)				C99	4.7

Other

Click to Show/Hide to Show 5 Protein Related to This Bioclass

Target ID	Target Name	Binding Sites	Binding Ratio
LDTP00843	Alpha-actinin-4 (ACTN4)	C879	5.6
LDTP03620	Protein S100-A11 (S100A11)	C13	4.6
LDTP05778	Chromobox protein homolog 3 (CBX3)	C160	3.8
LDTP13552	Protein HEG homolog 1 (HEG1)	C1360	3.3
LDTP14298	Actin-binding protein WASF2 (WASF2)	C27	3.1

References

1	Discovery of a Functional Covalent Ligand Targeting an Intrinsically Disordered Cysteine within MYC. Cell Chem Biol. 2021 Jan 21;28(1):4-13.e17. doi: 10.1016/j.chembiol.2020.09.001. Epub 2020 Sep 22.