General Information of Experiment

Probe Name Kambe_3  Probe Info 
Probe concentration 10 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
SILAC
Competitor Name Kambe_cp66  Competitor Info 
Competitor Concentration 20 uM
In Vivo Experiment Model Model Type Living cell
Derived Tissue Prostate
Disease Model Prostate carcinoma [ICD-11:2C82]
Model Name Human prostate carcinoma cells (PC-3)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 7 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03976  Aldo-keto reductase family 1 member C3 (AKR1C3) 20.0
 LDTP05632  Mitochondrial-processing peptidase subunit alpha (PMPCA) 3.2
 LDTP03730  Sepiapterin reductase (SPR) 3.1
 LDTP06227  Prostaglandin reductase 1 (PTGR1) 2.7
 LDTP04134  Retinaldehyde dehydrogenase 3 (ALDH1A3) 2.3
 LDTP04051  Nicotinamide phosphoribosyltransferase (NAMPT) 2.2
 LDTP04884  Proteasome subunit alpha type-6 (PSMA6) 2.0
Transporter and channel
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03132  Voltage-dependent anion-selective channel protein 1 (VDAC1) 3.6
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) 2.5
 LDTP12533  Ubiquilin-4 (UBQLN4) 2.0
Other
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP04094  Large proline-rich protein BAG6 (BAG6) 20.0
 LDTP03520  Phosphatidylethanolamine-binding protein 1 (PEBP1) 2.0

References

1 Mapping the protein interaction landscape for fully functionalized small-molecule probes in human cells. J Am Chem Soc. 2014 Jul 30;136(30):10777-82. doi: 10.1021/ja505517t. Epub 2014 Jul 21.