General Information of Target

Target ID LDTP18918
Target Name MORF4 family associated protein 1 like 2 (MRFAP1L2)
Gene Name MRFAP1L2
Synonyms
MORF4 family associated protein 1 like 2; MORF4 family-associated protein 1-like protein UPP; Unnamed protein product; UPP
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MACIENVLGGHAPSPLVVSVDKNGNQELHHDMPLQCLSSKPEDDAEPWGQPQVPLRPSVN
VLTDLDSKQLEWPSERTGSCIPLHSLRAHRHPYGPPPAVAEESLATAEVNSSDALAGWRQ
EGQDAINVSWEVSGGPPALIVGGTKVNNGGTERGSNNARLHVALPQGKGFFPPRGPQVRG
PSHIPTLRSGIVMEVPPGNTRIACRGKLAHVSFPLRGPCHPMHNWPRPIPLSSSTPGLPS
CSTVHCFIPPRPPIFNPFLTMPLPFAPPPIFGPPLPSYFAHFHSGGMPAPASPNREHS
Target Bioclass
Other
Family
MORF4 family-associated protein family
Function May play a role in cell proliferation.
Uniprot ID
B2RBV5
HGNC ID
HGNC:25109

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info 
C89(10.43)  LDD0205  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0103  BDHI 10 Jurkat C89(10.43)  LDD0205  [1]
 LDCM0106  BDHI 18 Jurkat C89(10.43)  LDD0208  [1]

References

1 Covalent Inhibition by a Natural Product-Inspired Latent Electrophile. J Am Chem Soc. 2023 May 24;145(20):11097-11109. doi: 10.1021/jacs.3c00598. Epub 2023 May 15.