Details of the Target

General Information of Target

Target ID LDTP18799
Target Name Maestro heat-like repeat-containing protein family member 6 (MROH6)
Gene Name MROH6
Gene ID 642475
Synonyms
C8orf73; Maestro heat-like repeat-containing protein family member 6
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPPPAPGARLRLLAAAALAGLAVISRGLLSQSLEFNSPADNYTVCEGDNATLSCFIDEHV
TRVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQP
YTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFTSEGEIL
EISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEA
MAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGAS
SASMRLLRPGSLENSAPRPPGLLALLSALGWLWWRM
Target Bioclass
Other
Uniprot ID
A6NGR9
Ensemble ID
ENST00000398882.8
HGNC ID
HGNC:27814

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C281(0.92)  LDD0531  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C281(0.92)  LDD0531  [1]
 LDCM0263  AC143 HCT 116 C281(1.08)  LDD0580  [1]
 LDCM0264  AC144 HCT 116 C281(0.99)  LDD0581  [1]
 LDCM0265  AC145 HCT 116 C281(0.80)  LDD0582  [1]
 LDCM0266  AC146 HCT 116 C281(1.27)  LDD0583  [1]
 LDCM0267  AC147 HCT 116 C281(1.03)  LDD0584  [1]
 LDCM0268  AC148 HCT 116 C281(0.81)  LDD0585  [1]
 LDCM0269  AC149 HCT 116 C281(1.17)  LDD0586  [1]
 LDCM0271  AC150 HCT 116 C281(1.12)  LDD0588  [1]
 LDCM0272  AC151 HCT 116 C281(1.26)  LDD0589  [1]
 LDCM0273  AC152 HCT 116 C281(1.41)  LDD0590  [1]
 LDCM0274  AC153 HCT 116 C281(1.11)  LDD0591  [1]
 LDCM0621  AC154 HCT 116 C281(1.27)  LDD2158  [1]
 LDCM0622  AC155 HCT 116 C281(1.43)  LDD2159  [1]
 LDCM0623  AC156 HCT 116 C281(1.25)  LDD2160  [1]
 LDCM0624  AC157 HCT 116 C281(1.18)  LDD2161  [1]
 LDCM0279  AC2 HCT 116 C281(0.92)  LDD0596  [1]
 LDCM0290  AC3 HCT 116 C281(0.86)  LDD0607  [1]
 LDCM0296  AC35 HCT 116 C281(0.82)  LDD0613  [1]
 LDCM0297  AC36 HCT 116 C281(0.93)  LDD0614  [1]
 LDCM0298  AC37 HCT 116 C281(0.77)  LDD0615  [1]
 LDCM0299  AC38 HCT 116 C281(1.08)  LDD0616  [1]
 LDCM0300  AC39 HCT 116 C281(1.02)  LDD0617  [1]
 LDCM0301  AC4 HCT 116 C281(0.84)  LDD0618  [1]
 LDCM0302  AC40 HCT 116 C281(0.91)  LDD0619  [1]
 LDCM0303  AC41 HCT 116 C281(1.00)  LDD0620  [1]
 LDCM0304  AC42 HCT 116 C281(1.03)  LDD0621  [1]
 LDCM0305  AC43 HCT 116 C281(1.09)  LDD0622  [1]
 LDCM0306  AC44 HCT 116 C281(0.90)  LDD0623  [1]
 LDCM0307  AC45 HCT 116 C281(0.81)  LDD0624  [1]
 LDCM0312  AC5 HCT 116 C281(0.87)  LDD0629  [1]
 LDCM0349  AC83 HCT 116 C281(1.19)  LDD0666  [1]
 LDCM0350  AC84 HCT 116 C281(1.26)  LDD0667  [1]
 LDCM0351  AC85 HCT 116 C281(1.12)  LDD0668  [1]
 LDCM0352  AC86 HCT 116 C281(1.08)  LDD0669  [1]
 LDCM0353  AC87 HCT 116 C281(1.19)  LDD0670  [1]
 LDCM0354  AC88 HCT 116 C281(1.30)  LDD0671  [1]
 LDCM0355  AC89 HCT 116 C281(1.27)  LDD0672  [1]
 LDCM0357  AC90 HCT 116 C281(1.25)  LDD0674  [1]
 LDCM0358  AC91 HCT 116 C281(0.98)  LDD0675  [1]
 LDCM0359  AC92 HCT 116 C281(0.99)  LDD0676  [1]
 LDCM0360  AC93 HCT 116 C281(1.18)  LDD0677  [1]
 LDCM0361  AC94 HCT 116 C281(1.00)  LDD0678  [1]
 LDCM0362  AC95 HCT 116 C281(1.40)  LDD0679  [1]
 LDCM0363  AC96 HCT 116 C281(0.85)  LDD0680  [1]
 LDCM0364  AC97 HCT 116 C281(1.26)  LDD0681  [1]
 LDCM0367  CL1 HCT 116 C281(1.63)  LDD0684  [1]
 LDCM0368  CL10 HCT 116 C281(1.57)  LDD0685  [1]
 LDCM0369  CL100 HCT 116 C281(1.04)  LDD0686  [1]
 LDCM0379  CL11 HCT 116 C281(2.28)  LDD0696  [1]
 LDCM0387  CL117 HCT 116 C281(1.16)  LDD0704  [1]
 LDCM0388  CL118 HCT 116 C281(1.00)  LDD0705  [1]
 LDCM0389  CL119 HCT 116 C281(1.00)  LDD0706  [1]
 LDCM0390  CL12 HCT 116 C281(1.73)  LDD0707  [1]
 LDCM0391  CL120 HCT 116 C281(1.04)  LDD0708  [1]
 LDCM0400  CL13 HCT 116 C281(0.91)  LDD0717  [1]
 LDCM0401  CL14 HCT 116 C281(1.27)  LDD0718  [1]
 LDCM0402  CL15 HCT 116 C281(1.29)  LDD0719  [1]
 LDCM0407  CL2 HCT 116 C281(1.13)  LDD0724  [1]
 LDCM0418  CL3 HCT 116 C281(1.22)  LDD0735  [1]
 LDCM0429  CL4 HCT 116 C281(1.10)  LDD0746  [1]
 LDCM0440  CL5 HCT 116 C281(0.83)  LDD0757  [1]
 LDCM0451  CL6 HCT 116 C281(1.19)  LDD0768  [1]
 LDCM0462  CL7 HCT 116 C281(1.33)  LDD0779  [1]
 LDCM0473  CL8 HCT 116 C281(2.73)  LDD0790  [1]
 LDCM0484  CL9 HCT 116 C281(1.31)  LDD0801  [1]
 LDCM0486  CL91 HCT 116 C281(0.88)  LDD0803  [1]
 LDCM0487  CL92 HCT 116 C281(0.98)  LDD0804  [1]
 LDCM0488  CL93 HCT 116 C281(0.92)  LDD0805  [1]
 LDCM0489  CL94 HCT 116 C281(0.97)  LDD0806  [1]
 LDCM0490  CL95 HCT 116 C281(1.53)  LDD0807  [1]
 LDCM0491  CL96 HCT 116 C281(0.95)  LDD0808  [1]
 LDCM0492  CL97 HCT 116 C281(1.01)  LDD0809  [1]
 LDCM0493  CL98 HCT 116 C281(0.94)  LDD0810  [1]
 LDCM0494  CL99 HCT 116 C281(0.87)  LDD0811  [1]

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.