Details of the Target

General Information of Target

Target ID LDTP18439
Target Name Zinc finger protein 532 (ZNF532)
Gene Name ZNF532
Gene ID 55205
Synonyms
KIAA1629; Zinc finger protein 532
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPLTGVGPGSCRRQIIRALCLLLLLLHAGSAKNIWKRALPARLAEKSRAEEAGAPGGPRQ
PRADRCPPPPRTLPPGACQAARCQADSECPRHRRCCYNGCAYACLEAVPPPPVLDWLVQP
KPRWLGGNGWLLDGPEEVLQAEACSTTEDGAEPLLCPSGYECHILSPGDVAEGIPNRGQC
VKQRRQADGRILRHKLYKEYPEGDSKNVAEPGRGQQKHFQ
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
Q9HCE3
Ensemble ID
ENST00000336078.8
HGNC ID
HGNC:30940

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C833(1.07)  LDD3323  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0259  AC14 HEK-293T C872(1.27)  LDD1512  [2]
 LDCM0270  AC15 HEK-293T C875(1.04)  LDD1513  [2]
 LDCM0281  AC21 HEK-293T C875(0.90)  LDD1520  [2]
 LDCM0282  AC22 HEK-293T C872(1.00)  LDD1521  [2]
 LDCM0283  AC23 HEK-293T C875(0.97)  LDD1522  [2]
 LDCM0289  AC29 HEK-293T C875(1.08)  LDD1528  [2]
 LDCM0291  AC30 HEK-293T C872(0.95)  LDD1530  [2]
 LDCM0292  AC31 HEK-293T C875(0.93)  LDD1531  [2]
 LDCM0298  AC37 HEK-293T C875(1.22)  LDD1537  [2]
 LDCM0299  AC38 HEK-293T C872(1.11)  LDD1538  [2]
 LDCM0300  AC39 HEK-293T C875(0.99)  LDD1539  [2]
 LDCM0307  AC45 HEK-293T C875(1.03)  LDD1546  [2]
 LDCM0308  AC46 HEK-293T C872(0.96)  LDD1547  [2]
 LDCM0309  AC47 HEK-293T C875(1.40)  LDD1548  [2]
 LDCM0312  AC5 HEK-293T C875(1.13)  LDD1551  [2]
 LDCM0316  AC53 HEK-293T C875(1.12)  LDD1555  [2]
 LDCM0317  AC54 HEK-293T C872(1.01)  LDD1556  [2]
 LDCM0318  AC55 HEK-293T C875(1.17)  LDD1557  [2]
 LDCM0323  AC6 HEK-293T C872(1.06)  LDD1562  [2]
 LDCM0325  AC61 HEK-293T C875(1.01)  LDD1564  [2]
 LDCM0326  AC62 HEK-293T C872(0.96)  LDD1565  [2]
 LDCM0327  AC63 HEK-293T C875(0.97)  LDD1566  [2]
 LDCM0334  AC7 HEK-293T C875(1.10)  LDD1568  [2]
 LDCM0248  AKOS034007472 HEK-293T C875(1.08)  LDD1511  [2]
 LDCM0368  CL10 HEK-293T C872(1.41)  LDD1572  [2]
 LDCM0379  CL11 HEK-293T C875(1.49)  LDD1583  [2]
 LDCM0409  CL21 HEK-293T C875(0.96)  LDD1613  [2]
 LDCM0410  CL22 HEK-293T C872(1.54)  LDD1614  [2]
 LDCM0411  CL23 HEK-293T C875(1.28)  LDD1615  [2]
 LDCM0422  CL33 HEK-293T C875(0.96)  LDD1626  [2]
 LDCM0423  CL34 HEK-293T C872(1.30)  LDD1627  [2]
 LDCM0424  CL35 HEK-293T C875(1.21)  LDD1628  [2]
 LDCM0435  CL45 HEK-293T C875(1.05)  LDD1639  [2]
 LDCM0436  CL46 HEK-293T C872(1.50)  LDD1640  [2]
 LDCM0437  CL47 HEK-293T C875(1.25)  LDD1641  [2]
 LDCM0448  CL57 HEK-293T C875(0.93)  LDD1651  [2]
 LDCM0449  CL58 HEK-293T C872(1.26)  LDD1652  [2]
 LDCM0450  CL59 HEK-293T C875(1.27)  LDD1653  [2]
 LDCM0461  CL69 HEK-293T C875(1.15)  LDD1664  [2]
 LDCM0463  CL70 HEK-293T C872(1.33)  LDD1666  [2]
 LDCM0464  CL71 HEK-293T C875(1.01)  LDD1667  [2]
 LDCM0475  CL81 HEK-293T C875(1.13)  LDD1678  [2]
 LDCM0476  CL82 HEK-293T C872(1.23)  LDD1679  [2]
 LDCM0477  CL83 HEK-293T C875(0.88)  LDD1680  [2]
 LDCM0484  CL9 HEK-293T C875(0.86)  LDD1687  [2]
 LDCM0488  CL93 HEK-293T C875(1.00)  LDD1691  [2]
 LDCM0489  CL94 HEK-293T C872(1.38)  LDD1692  [2]
 LDCM0490  CL95 HEK-293T C875(1.14)  LDD1693  [2]
 LDCM0022  KB02 42-MG-BA C833(1.14)  LDD2244  [1]
 LDCM0023  KB03 769-P C270(1.70)  LDD2663  [1]
 LDCM0024  KB05 SKMEL24 C833(1.07)  LDD3323  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Importin subunit alpha-3 (KPNA4) Importin alpha family O00629

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
2 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402